fentanyl has been researched along with Hemorrhage in 29 studies
Fentanyl: A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078)
fentanyl : A monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of N-phenyl-1-(2-phenylethyl)piperidin-4-amine with propanoic acid.
Hemorrhage: Bleeding or escape of blood from a vessel.
Excerpt | Relevance | Reference |
---|---|---|
" alfentanil in 66 unpremedicated patients undergoing suction termination of pregnancy as outpatients." | 9.05 | Outpatient termination of pregnancy: halothane or alfentanil-supplemented anaesthesia. ( Collins, KM; Doyle, JP; Plantevin, OM; Whitburn, RH, 1985) |
"Sprague-Dawley rats (11-13 weeks) were randomly assigned to control (saline vehicle), fentanyl, or ketamine-treated groups with or without hemorrhage (n = 8 or 9 for each group)." | 7.96 | Fentanyl impairs but ketamine preserves the microcirculatory response to hemorrhage. ( Calderon, AS; Hinojosa-Laborde, C; Klemcke, HG; Ryan, KL; Scott, LL; Xiang, L, 2020) |
" Propofol-based anesthesia is favored in order to enhance TcMEP quality." | 7.88 | Changes in transcranial motor evoked potentials during hemorrhage are associated with increased serum propofol concentrations. ( Feiner, J; Jasiukaitis, P; Lieberman, JA; Lyon, R; Rollins, M, 2018) |
"Possible modulatory effects of mu-, delta-, and kappa-receptor agonists on the concurrent adrenal secretion of catecholamines and met-enkephalin evoked by staged hemorrhage were examined in four groups of cats (n = 5 in each group) anesthetized with halothane (1 MAC)." | 7.67 | Opioids preserve the adrenal medullary response evoked by severe hemorrhage: studies on adrenal catecholamine and met-enkephalin secretion in halothane anesthetized cats. ( Gaumann, DM; Lucas, DL; Tyce, GM; Yaksh, TL, 1988) |
"Hemorrhage is a leading cause of battlefield and civilian trauma deaths." | 7.11 | Low-dose fentanyl does not alter muscle sympathetic nerve activity, blood pressure, or tolerance during progressive central hypovolemia. ( Belval, LN; Cimino, FA; Crandall, CG; Fischer, M; Hendrix, JM; Huang, M; Jarrard, CP; Laborde, CH; Watso, JC, 2022) |
"Diffuse alveolar hemorrhage is a rare complication of fentanyl overdose." | 5.43 | Intranasal Fentanyl Intoxication Leading to Diffuse Alveolar Hemorrhage. ( Dunham, M; Ruzycki, S; Sadrzadeh, H; Tremblay, A; Yarema, M, 2016) |
" alfentanil in 66 unpremedicated patients undergoing suction termination of pregnancy as outpatients." | 5.05 | Outpatient termination of pregnancy: halothane or alfentanil-supplemented anaesthesia. ( Collins, KM; Doyle, JP; Plantevin, OM; Whitburn, RH, 1985) |
"Sprague-Dawley rats (11-13 weeks) were randomly assigned to control (saline vehicle), fentanyl, or ketamine-treated groups with or without hemorrhage (n = 8 or 9 for each group)." | 3.96 | Fentanyl impairs but ketamine preserves the microcirculatory response to hemorrhage. ( Calderon, AS; Hinojosa-Laborde, C; Klemcke, HG; Ryan, KL; Scott, LL; Xiang, L, 2020) |
" Propofol-based anesthesia is favored in order to enhance TcMEP quality." | 3.88 | Changes in transcranial motor evoked potentials during hemorrhage are associated with increased serum propofol concentrations. ( Feiner, J; Jasiukaitis, P; Lieberman, JA; Lyon, R; Rollins, M, 2018) |
"Possible modulatory effects of mu-, delta-, and kappa-receptor agonists on the concurrent adrenal secretion of catecholamines and met-enkephalin evoked by staged hemorrhage were examined in four groups of cats (n = 5 in each group) anesthetized with halothane (1 MAC)." | 3.67 | Opioids preserve the adrenal medullary response evoked by severe hemorrhage: studies on adrenal catecholamine and met-enkephalin secretion in halothane anesthetized cats. ( Gaumann, DM; Lucas, DL; Tyce, GM; Yaksh, TL, 1988) |
"Hemorrhage is a leading cause of preventable battlefield and civilian trauma deaths." | 3.30 | Comparing the Effects of Low-Dose Ketamine, Fentanyl, and Morphine on Hemorrhagic Tolerance and Analgesia in Humans. ( Belval, LN; Cramer, MN; Crandall, CG; Foster, J; Hendrix, JM; Hinojosa-Laborde, C; Huang, M; Moralez, G; Watso, JC, 2023) |
"Hemorrhage is a leading cause of battlefield and civilian trauma deaths." | 3.11 | Low-dose fentanyl does not alter muscle sympathetic nerve activity, blood pressure, or tolerance during progressive central hypovolemia. ( Belval, LN; Cimino, FA; Crandall, CG; Fischer, M; Hendrix, JM; Huang, M; Jarrard, CP; Laborde, CH; Watso, JC, 2022) |
"A fentanyl bolus was administered to 8 of 10 dogs treated with fentanyl and to none treated with TA." | 2.78 | Perioperative evaluation of tumescent anaesthesia technique in bitches submitted to unilateral mastectomy. ( Credie, Lde F; da Silva, LC; de Carvalho, LR; Futema, F; Garcia, JN; Gomes, GB; Luna, SP, 2013) |
"Diffuse alveolar hemorrhage is a rare complication of fentanyl overdose." | 1.43 | Intranasal Fentanyl Intoxication Leading to Diffuse Alveolar Hemorrhage. ( Dunham, M; Ruzycki, S; Sadrzadeh, H; Tremblay, A; Yarema, M, 2016) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 17 (58.62) | 18.7374 |
1990's | 1 (3.45) | 18.2507 |
2000's | 4 (13.79) | 29.6817 |
2010's | 4 (13.79) | 24.3611 |
2020's | 3 (10.34) | 2.80 |
Authors | Studies |
---|---|
Huang, M | 2 |
Watso, JC | 2 |
Belval, LN | 2 |
Cimino, FA | 1 |
Fischer, M | 1 |
Jarrard, CP | 1 |
Hendrix, JM | 2 |
Laborde, CH | 1 |
Crandall, CG | 2 |
Moralez, G | 1 |
Cramer, MN | 1 |
Foster, J | 1 |
Hinojosa-Laborde, C | 2 |
Xiang, L | 1 |
Calderon, AS | 1 |
Klemcke, HG | 1 |
Scott, LL | 1 |
Ryan, KL | 1 |
Lieberman, JA | 1 |
Feiner, J | 1 |
Rollins, M | 1 |
Lyon, R | 1 |
Jasiukaitis, P | 1 |
Credie, Lde F | 1 |
Luna, SP | 1 |
Futema, F | 1 |
da Silva, LC | 1 |
Gomes, GB | 1 |
Garcia, JN | 1 |
de Carvalho, LR | 1 |
Ruzycki, S | 1 |
Yarema, M | 1 |
Dunham, M | 1 |
Sadrzadeh, H | 1 |
Tremblay, A | 1 |
Silva, C | 1 |
Pinheiro, F | 1 |
Chieira, D | 1 |
Marques, S | 1 |
Órfão, MR | 1 |
O'Flaherty, JE | 1 |
Lin, CX | 1 |
Takizawa, D | 1 |
Sato, E | 1 |
Kurosaki, D | 1 |
Hiraoka, H | 1 |
Saito, S | 1 |
Goto, F | 1 |
Disma, N | 1 |
Astuto, M | 1 |
Giorgio, AD | 1 |
Russo, G | 1 |
Lehtinen, AM | 1 |
Meites, G | 1 |
Portecazaux, A | 1 |
Pessey, JJ | 1 |
Modig, J | 1 |
Borg, T | 1 |
Karlström, G | 1 |
Maripuu, E | 1 |
Sahlstedt, B | 1 |
Woodward, G | 1 |
Grigor'ev, MG | 1 |
Beliakov, VA | 1 |
Kalachev, SA | 1 |
Dilger, JA | 1 |
Tetzlaff, JE | 1 |
Bell, GR | 1 |
Kosmorsky, GS | 1 |
Agnor, RC | 1 |
O'Hara, JF | 1 |
Brookes, ZL | 1 |
Brown, NJ | 1 |
Reilly, CS | 1 |
Fishburne, JI | 1 |
Esclamado, RM | 1 |
Glenn, MG | 1 |
McCulloch, TM | 1 |
Cummings, CW | 1 |
Gaumann, DM | 1 |
Yaksh, TL | 1 |
Tyce, GM | 1 |
Lucas, DL | 1 |
Saini, V | 1 |
Carr, DB | 1 |
Hagestad, EL | 1 |
Lown, B | 1 |
Verrier, RL | 1 |
Collins, KM | 1 |
Plantevin, OM | 1 |
Whitburn, RH | 1 |
Doyle, JP | 1 |
Patel, S | 1 |
McNeill, TW | 1 |
DeWald, RL | 1 |
Kuo, KN | 1 |
Bennett, EJ | 1 |
Salem, MR | 1 |
Skoblin, AP | 1 |
Grabovoĭ, AF | 1 |
Semergeĭ, IK | 1 |
Skovsted, P | 1 |
Misfeldt, BB | 1 |
Mogensen, JV | 1 |
Brockner, J | 1 |
Bond, RF | 1 |
Roberts, DE | 1 |
Manning, ES | 1 |
Knape, H | 1 |
Pacelli, L | 1 |
Liverta, E | 1 |
Achilli, M | 1 |
Movilia, PG | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Evaluation of Treatment Effect of Cervical Collar in Moderate Obstructive Sleep Apnea[NCT03754270] | 100 participants (Actual) | Interventional | 2019-06-16 | Completed | |||
The Association of CPAP Compliance and Nocturnal Hypoxemia in the Perioperative Period[NCT02796846] | 158 participants (Actual) | Observational | 2015-06-30 | Completed | |||
Evaluation of Screening Tools for OSA in Hospitalized Medical Patients: A Validation Study[NCT01340781] | 110 participants (Actual) | Observational | 2012-02-29 | Completed | |||
The Effect of Acute Intravenous Morphine Administration on Sleep Disordered Breathing (SDB) in Patients With Moderate Obstructive Sleep Apnoea (OSA): A Paired Design Trial[NCT03127800] | Phase 3 | 6 participants (Actual) | Interventional | 2016-05-20 | Terminated (stopped due to Difficulties with recruitment) | ||
Sevoflurane as an Anesthetic During Dilation and Evacuation Procedures: Does it Increase Blood Loss and Interventions for Blood Loss and Why Do Anesthesiologists Choose to Use It?[NCT01048658] | Phase 4 | 160 participants (Actual) | Interventional | 2009-09-30 | Completed | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
(NCT01048658)
Timeframe: Post-procedure, within 30 minutes
Intervention | Participants (Count of Participants) |
---|---|
Sevoflurane | 13 |
No Sevoflurane | 11 |
Provider report for need to intervene due to blood loss (yes/no) (NCT01048658)
Timeframe: At time of uterine evacuation and immediately post-operatively, an average of 7.1 minutes
Intervention | Participants (Count of Participants) |
---|---|
Sevoflurane | 20 |
No Sevoflurane | 13 |
Procedural blood loss greater than 300 mL. Blood loss was measured in a standardized fashion (amniotic fluid was discarded, blood was separated from tissue, and all gauze surgical drapes weighed). (NCT01048658)
Timeframe: At time of uterine evacuation, an average of 7.1 minutes
Intervention | Participants (Count of Participants) |
---|---|
Sevoflurane | 12 |
No Sevoflurane | 6 |
Length of procedure from time of speculum placement to time of speculum removal, in minutes. (NCT01048658)
Timeframe: Time of speculum place to time of speculum removal, an average of 7.1 minutes
Intervention | minutes (Mean) |
---|---|
Sevoflurane | 7.0 |
No Sevoflurane | 7.3 |
Scores reported on 10-cm Visual Analog Scale (VAS anchors: 0= not satisfied at all, 10= completely satisfied) . Reported as mean +/- standard deviation. Subjects and providers were blinded to anesthesia method. Subjects and providers completed post-operative questionnaire within 30 minutes of procedure completion. (NCT01048658)
Timeframe: Post-procedure, within 30 minutes
Intervention | cm (Mean) | |
---|---|---|
Provider Satisfaction | Patient Satisfaction | |
No Sevoflurane | 9.3 | 8.2 |
Sevoflurane | 9.4 | 8.4 |
1 review available for fentanyl and Hemorrhage
Article | Year |
---|---|
Antifibrillatory action of the narcotic agonist fentanyl.
Topics: Animals; Atropine; Atropine Derivatives; Blood Pressure; Cardiac Pacing, Artificial; Dogs; Electric | 1988 |
7 trials available for fentanyl and Hemorrhage
Article | Year |
---|---|
Low-dose fentanyl does not alter muscle sympathetic nerve activity, blood pressure, or tolerance during progressive central hypovolemia.
Topics: Adult; Analgesics, Opioid; Blood Pressure; Cardiovascular System; Cross-Over Studies; Double-Blind M | 2022 |
Comparing the Effects of Low-Dose Ketamine, Fentanyl, and Morphine on Hemorrhagic Tolerance and Analgesia in Humans.
Topics: Adult; Analgesia; Analgesics; Analgesics, Opioid; Cross-Over Studies; Emergency Medical Services; Fe | 2023 |
Perioperative evaluation of tumescent anaesthesia technique in bitches submitted to unilateral mastectomy.
Topics: Analgesics, Opioid; Anesthetics, Local; Animals; Dog Diseases; Dogs; Female; Fentanyl; Hemorrhage; I | 2013 |
Does ketamine or magnesium affect posttonsillectomy pain in children?
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Dissociative; Child; Child | 2003 |
Thromboembolism after total hip replacement: role of epidural and general anesthesia.
Topics: Aged; Anesthesia, Epidural; Anesthesia, General; Bupivacaine; Epinephrine; Female; Fentanyl; Hemorrh | 1983 |
Intraoperative blood loss in midtrimester dilatation and extraction.
Topics: Abortion, Induced; Dilatation; Epinephrine; Female; Fentanyl; Hemorrhage; Humans; Intraoperative Com | 1983 |
Outpatient termination of pregnancy: halothane or alfentanil-supplemented anaesthesia.
Topics: Abortion, Induced; Adjuvants, Anesthesia; Adolescent; Adult; Alfentanil; Ambulatory Surgical Procedu | 1985 |
21 other studies available for fentanyl and Hemorrhage
Article | Year |
---|---|
Fentanyl impairs but ketamine preserves the microcirculatory response to hemorrhage.
Topics: Administration, Topical; Analgesics; Analgesics, Opioid; Animals; Blood Pressure; Fentanyl; Heart Ra | 2020 |
Changes in transcranial motor evoked potentials during hemorrhage are associated with increased serum propofol concentrations.
Topics: Anesthesia; Anesthetics, Intravenous; Animals; Arterial Pressure; Blood Pressure; Cardiac Output; El | 2018 |
Intranasal Fentanyl Intoxication Leading to Diffuse Alveolar Hemorrhage.
Topics: Administration, Inhalation; Alberta; Analgesics, Opioid; Combined Modality Therapy; Diagnosis, Diffe | 2016 |
Anesthetic Management of an Acute Bleeding Ventriculo-Cutaneous Fistula.
Topics: Aged, 80 and over; Androstanols; Anesthesia; Anesthetics, Inhalation; Anesthetics, Intravenous; Cuta | 2016 |
Changes in unbound concentration of propofol during hemorrhage.
Topics: Anesthesia; Blood Pressure; Blood Transfusion; Dopamine; Female; Fentanyl; Heart Rate; Hemorrhage; H | 2005 |
Scurvy: a disease of anesthetic interest? Scurvy and anesthesia.
Topics: Airway Obstruction; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Ascorbic | 2008 |
Opiate action on adenohypophyseal hormone secretion during anesthesia and gynecologic surgery in different phases of the menstrual cycle.
Topics: Adult; Anesthesia; Anesthesia, General; Anesthesia, Inhalation; Endorphins; Female; Fentanyl; Genita | 1981 |
[Importance of flunitrazepam for the reduction of bleeding in rhinoplasty].
Topics: Adolescent; Adult; Female; Fentanyl; Flunitrazepam; Hemorrhage; Humans; Intraoperative Complications | 1984 |
[Role of hypervolemic hemodilution and controlled hypotension in decreasing the blood loss during traumatic operations].
Topics: Adolescent; Adult; Blood Volume; Child; Child, Preschool; Female; Fentanyl; Hemodilution; Hemorrhage | 1980 |
Ischaemic optic neuropathy after spinal fusion.
Topics: Adult; Anesthesia, Intravenous; Anesthetics, Inhalation; Anesthetics, Intravenous; Blood Loss, Surgi | 1998 |
Differential effects of intravenous anaesthetic agents on the response of rat mesenteric microcirculation in vivo after haemorrhage.
Topics: Anesthetics, Combined; Anesthetics, Intravenous; Animals; Fentanyl; Hemodynamics; Hemorrhage; Ketami | 2002 |
Office laparoscopic sterilization with local anesthesia.
Topics: Adult; Anesthesia, Local; Bupivacaine; Female; Fentanyl; Hemorrhage; Humans; Laparoscopy; Middle Age | 1977 |
Perioperative complications and risk factors in the surgical treatment of obstructive sleep apnea syndrome.
Topics: Adjuvants, Anesthesia; Adult; Airway Obstruction; Arrhythmias, Cardiac; Chi-Square Distribution; Fem | 1989 |
Perioperative complications and risk factors in the surgical treatment of obstructive sleep apnea syndrome.
Topics: Adjuvants, Anesthesia; Adult; Airway Obstruction; Arrhythmias, Cardiac; Chi-Square Distribution; Fem | 1989 |
Perioperative complications and risk factors in the surgical treatment of obstructive sleep apnea syndrome.
Topics: Adjuvants, Anesthesia; Adult; Airway Obstruction; Arrhythmias, Cardiac; Chi-Square Distribution; Fem | 1989 |
Perioperative complications and risk factors in the surgical treatment of obstructive sleep apnea syndrome.
Topics: Adjuvants, Anesthesia; Adult; Airway Obstruction; Arrhythmias, Cardiac; Chi-Square Distribution; Fem | 1989 |
Perioperative complications and risk factors in the surgical treatment of obstructive sleep apnea syndrome.
Topics: Adjuvants, Anesthesia; Adult; Airway Obstruction; Arrhythmias, Cardiac; Chi-Square Distribution; Fem | 1989 |
Perioperative complications and risk factors in the surgical treatment of obstructive sleep apnea syndrome.
Topics: Adjuvants, Anesthesia; Adult; Airway Obstruction; Arrhythmias, Cardiac; Chi-Square Distribution; Fem | 1989 |
Perioperative complications and risk factors in the surgical treatment of obstructive sleep apnea syndrome.
Topics: Adjuvants, Anesthesia; Adult; Airway Obstruction; Arrhythmias, Cardiac; Chi-Square Distribution; Fem | 1989 |
Perioperative complications and risk factors in the surgical treatment of obstructive sleep apnea syndrome.
Topics: Adjuvants, Anesthesia; Adult; Airway Obstruction; Arrhythmias, Cardiac; Chi-Square Distribution; Fem | 1989 |
Perioperative complications and risk factors in the surgical treatment of obstructive sleep apnea syndrome.
Topics: Adjuvants, Anesthesia; Adult; Airway Obstruction; Arrhythmias, Cardiac; Chi-Square Distribution; Fem | 1989 |
Perioperative complications and risk factors in the surgical treatment of obstructive sleep apnea syndrome.
Topics: Adjuvants, Anesthesia; Adult; Airway Obstruction; Arrhythmias, Cardiac; Chi-Square Distribution; Fem | 1989 |
Perioperative complications and risk factors in the surgical treatment of obstructive sleep apnea syndrome.
Topics: Adjuvants, Anesthesia; Adult; Airway Obstruction; Arrhythmias, Cardiac; Chi-Square Distribution; Fem | 1989 |
Perioperative complications and risk factors in the surgical treatment of obstructive sleep apnea syndrome.
Topics: Adjuvants, Anesthesia; Adult; Airway Obstruction; Arrhythmias, Cardiac; Chi-Square Distribution; Fem | 1989 |
Perioperative complications and risk factors in the surgical treatment of obstructive sleep apnea syndrome.
Topics: Adjuvants, Anesthesia; Adult; Airway Obstruction; Arrhythmias, Cardiac; Chi-Square Distribution; Fem | 1989 |
Perioperative complications and risk factors in the surgical treatment of obstructive sleep apnea syndrome.
Topics: Adjuvants, Anesthesia; Adult; Airway Obstruction; Arrhythmias, Cardiac; Chi-Square Distribution; Fem | 1989 |
Perioperative complications and risk factors in the surgical treatment of obstructive sleep apnea syndrome.
Topics: Adjuvants, Anesthesia; Adult; Airway Obstruction; Arrhythmias, Cardiac; Chi-Square Distribution; Fem | 1989 |
Perioperative complications and risk factors in the surgical treatment of obstructive sleep apnea syndrome.
Topics: Adjuvants, Anesthesia; Adult; Airway Obstruction; Arrhythmias, Cardiac; Chi-Square Distribution; Fem | 1989 |
Opioids preserve the adrenal medullary response evoked by severe hemorrhage: studies on adrenal catecholamine and met-enkephalin secretion in halothane anesthetized cats.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adrenal Me | 1988 |
Intraoperative therapy for massive blood loss.
Topics: Adult; Anesthesia, Intravenous; Blood Coagulation Disorders; Blood Transfusion; Fentanyl; Fluid Ther | 1986 |
Controlled hypotensive anesthesia in scoliosis surgery.
Topics: Adjuvants, Anesthesia; Anesthesia, Inhalation; Benperidol; Child; Fentanyl; Halothane; Hemorrhage; H | 1974 |
[Resuscitative-anesthesiologic provisions in extensive surgical operations in the thorax and spine for scoliosis].
Topics: Adolescent; Adult; Anesthesia, Endotracheal; Child; Fentanyl; Hemorrhage; Humans; Hypotension, Contr | 1974 |
The effects of anesthesia on blood loss at caesarean section.
Topics: Adult; Anesthesia, General; Anesthesia, Obstetrical; Blood Transfusion; Cesarean Section; Droperidol | 1973 |
Effects of anesthetics on myocardial contractility and total body O2 consumption during hemorrhage.
Topics: Anesthesia, Intravenous; Anesthetics; Animals; Blood Pressure; Chloralose; Dogs; Droperidol; Female; | 1973 |
A comparison of neuroleptanesthesia and halothane in neurosurgery.
Topics: Adolescent; Adult; Aged; Anesthesia, Inhalation; Blood Pressure; Child; Consciousness; Female; Fenta | 1970 |
[Technics of general anesthesia to control bleeding in nasal surgery].
Topics: Adolescent; Adult; Aged; Anesthesia, General; Benperidol; Drainage; Fentanyl; Halothane; Hemorrhage; | 1968 |