Page last updated: 2024-10-27

fentanyl and Dizziness

fentanyl has been researched along with Dizziness in 19 studies

Fentanyl: A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078)
fentanyl : A monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of N-phenyl-1-(2-phenylethyl)piperidin-4-amine with propanoic acid.

Dizziness: An imprecise term which may refer to a sense of spatial disorientation, motion of the environment, or lightheadedness.

Research Excerpts

ExcerptRelevanceReference
"In this study, we aimed to compare the analgesic efficacy of intravenous dexketoprofen trometamol, fentanyl, and paracetamol in patients presenting to the emergency department with renal colic."9.27Comparison of IV dexketoprofen trometamol, fentanyl, and paracetamol in the treatment of renal colic in the ED: A randomized controlled trial. ( Al, B; Bogan, M; Can, B; Eren, SH; Kul, S; Murat Oktay, M; Sabak, M; Sunar, MM; Zengin, S, 2018)
"In this study we evaluated the efficacy and tolerability of sublingual fentanyl (SLF) for breakthrough pain (BTP) in adult opioid-tolerant cancer patients."9.14Sublingual administration of fentanyl to cancer patients is an effective treatment for breakthrough pain: results from a randomized phase II study. ( Derrick, R; Frank-Lissbrant, I; Howell, J; Kälkner, KM; Lennernäs, B; Lennernäs, H, 2010)
"Compared with fentanyl and oxycodone, butorphanol prolonged the recovery of bowel function with more severe somnolence and dizziness, suggesting that butorphanol is not well suitable for IV-PCA in patients undergoing laparoscopic hysterectomy."5.51The effects of fentanyl, oxycodone, and butorphanol on gastrointestinal function in patients undergoing laparoscopic hysterectomy: a prospective, double-blind, randomized controlled trial. ( Gao, J; Guo, M; Han, C; Liu, C; Liu, S; Yang, C, 2022)
"In this study, we aimed to compare the analgesic efficacy of intravenous dexketoprofen trometamol, fentanyl, and paracetamol in patients presenting to the emergency department with renal colic."5.27Comparison of IV dexketoprofen trometamol, fentanyl, and paracetamol in the treatment of renal colic in the ED: A randomized controlled trial. ( Al, B; Bogan, M; Can, B; Eren, SH; Kul, S; Murat Oktay, M; Sabak, M; Sunar, MM; Zengin, S, 2018)
"In this study we evaluated the efficacy and tolerability of sublingual fentanyl (SLF) for breakthrough pain (BTP) in adult opioid-tolerant cancer patients."5.14Sublingual administration of fentanyl to cancer patients is an effective treatment for breakthrough pain: results from a randomized phase II study. ( Derrick, R; Frank-Lissbrant, I; Howell, J; Kälkner, KM; Lennernäs, B; Lennernäs, H, 2010)
" There were no differences between the groups with respect to incidence of pruritus, sedation, and nausea; however, vomiting occurred more frequently with sufentanil than with fentanyl (12% vs."5.07Postcesarean delivery epidural patient-controlled analgesia. Fentanyl or sufentanil? ( Amar, D; Brady, JA; Cohen, S; Goodman, EJ; Kanas, RJ; Pantuck, CB; Pantuck, EJ; Widroff, JS, 1993)
"The rates of respiratory depression (1."3.11Effect of additional equipotent fentanyl or sufentanil administration on recovery profiles during propofol-remifentanil-based anaesthesia in patients undergoing gynaecologic laparoscopic surgery: a randomized clinical trial. ( Huang, D; Huang, J; Jian, Q; Li, P; Ma, J; Xie, H; Zeng, W; Zhang, C, 2022)
"Modafinil 200 mg was administered to the treatment group patients 1 h before sedation/analgesia."2.75Modafinil reduces patient-reported tiredness after sedation/analgesia but does not improve patient psychomotor skills. ( Boesjes, H; Galvin, E; Hol, J; Klein, J; Ubben, JF; Verbrugge, SJ, 2010)
"However, postoperative nausea and vomiting was significantly lower in groups II and III (p < 0."2.73Postoperative intravenous patient-controlled analgesia in thyroid surgery: comparison of fentanyl and ondansetron regimens with and without the nonsteriodal anti-inflammatory drug ketorolac. ( Chang, DJ; Kim, EM; Kim, KJ; Kim, SY; Nam, KH; Nam, SH, 2008)
"The hearing loss was unilateral in two and bilateral in four patients."2.73Hearing loss after spinal anesthesia: the effect of different infusion solutions. ( Iseri, M; Karaca, B; Solak, M; Toker, K; Yildiz, TS, 2007)
"Oral transmucosal fentanyl citrate (OTFC) is a novel lozenge dosage form of fentanyl used for premedication."2.67Oral transmucosal fentanyl citrate premedication in patients undergoing outpatient dermatologic procedures. ( Bezzant, JL; Gerwels, JW; Le Maire, L; Pauley, LF; Streisand, JB, 1994)
"Fentanyl utilisation was significantly lower in group FB (median 41 versus 53 micrograms/hr, P < 0."2.67Postoperative epidural fentanyl infusion--is the addition of 0.1% bupivacaine of benefit? ( Paech, MJ; Westmore, MD, 1994)
"The objectives of this study were to describe the type and frequency of postdischarge adverse events related to sedation for elective diagnostic imaging in children and to determine if any patient or drug characteristics were associated with such adverse events."1.38Postdischarge adverse events related to sedation for diagnostic imaging in children. ( Chen, X; Kaila, R; Kannikeswaran, N, 2012)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19901 (5.26)18.7374
1990's5 (26.32)18.2507
2000's3 (15.79)29.6817
2010's8 (42.11)24.3611
2020's2 (10.53)2.80

Authors

AuthorsStudies
Guo, M1
Liu, S1
Gao, J1
Han, C1
Yang, C1
Liu, C1
Zhang, C1
Huang, D2
Zeng, W1
Ma, J1
Li, P1
Jian, Q1
Huang, J1
Xie, H1
Al, B1
Sunar, MM1
Zengin, S1
Sabak, M1
Bogan, M1
Can, B1
Kul, S1
Murat Oktay, M1
Eren, SH1
Chew, KS1
Shaharudin, AH1
Kim, SY1
Kim, EM1
Nam, KH1
Chang, DJ1
Nam, SH1
Kim, KJ1
Galvin, E1
Boesjes, H1
Hol, J1
Ubben, JF1
Klein, J1
Verbrugge, SJ1
Lennernäs, B1
Frank-Lissbrant, I1
Lennernäs, H1
Kälkner, KM1
Derrick, R1
Howell, J1
Minkowski, CP1
Epstein, D1
Frost, JJ1
Gorelick, DA1
Hand, D1
Averley, P1
Lyne, J1
Girdler, N1
Kaila, R1
Chen, X1
Kannikeswaran, N1
Liao, Q1
Chen, DJ1
Zhang, F1
Li, L1
Hu, R1
Tang, YZ1
Ou-Yang, W1
Yildiz, TS1
Solak, M1
Iseri, M1
Karaca, B1
Toker, K1
Darwish, M1
Kirby, M1
Jiang, JG1
Tracewell, W1
Robertson, P1
Gerwels, JW1
Bezzant, JL1
Le Maire, L1
Pauley, LF1
Streisand, JB1
Morris, GF1
Gore-Hickman, W1
Lang, SA1
Yip, RW1
Paech, MJ1
Westmore, MD1
Hayashi, H1
Nishiuchi, T1
Tamura, H1
Takeda, K1
Cohen, S1
Amar, D1
Pantuck, CB1
Pantuck, EJ1
Goodman, EJ1
Widroff, JS1
Kanas, RJ1
Brady, JA1
Wetchler, BV1
Alexander, CD1
Shariff, MS1
Gaudzels, GM1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Comparison of the Effects of Fentanyl, Oxycodone, Butorphanol on Gastrointestinal Function in Patients Undergoing Laparoscopic Hysterectomy: a Double-blind, a Randomized Controlled Trial[NCT04295109]105 participants (Anticipated)Interventional2020-03-02Recruiting
A Randomized, Double Blind, Placebo Controlled Evaluation of Modafinil vs Placebo for the Treatment of General Anesthesia Related Delayed Emergence in Patients With the Diagnosis of Obstructive Sleep Apnea[NCT02494102]Phase 4105 participants (Actual)Interventional2016-02-29Terminated
Use of Sevoflurane, Midazolam and Ketamine in Children for Dental Sedation Treatment: Occurrence of Adverse Events[NCT02284204]Phase 227 participants (Actual)Interventional2012-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Length of Time From Extubation to Discharge From Postanesthesia Recovery Unit

Length of time of above compared between groups (NCT02494102)
Timeframe: 24 hours

Interventionminutes (Mean)
Placebo53.5
Modafinil61.0

Postanesthesia Quality Recovery Scale Score

Postanesthesia quality recovery scale (PQRS). Component and aggregate scoring on the scale. Measures physiology, nociceptive, emotional activities of daily living cognitive and overall patient perspective. The scale is dimensionless and the aggregate of all individually tested dimensions is scaled from 17-65. A higher value implies improved postanesthesia recovery. Mean difference was assessed in each patient and aggregated thus patients with no difference between pre- and post-operative scores were zeroed (received a zero score if the difference was zero). A negative value was associated with worse outcome. (NCT02494102)
Timeframe: baseline and 6 hours after surgery

Interventionunits on a scale (Mean)
Placebo-5.67
Modafinil-8.91

Trials

14 trials available for fentanyl and Dizziness

ArticleYear
The effects of fentanyl, oxycodone, and butorphanol on gastrointestinal function in patients undergoing laparoscopic hysterectomy: a prospective, double-blind, randomized controlled trial.
    BMC anesthesiology, 2022, 02-24, Volume: 22, Issue:1

    Topics: Analgesics, Opioid; Butorphanol; Dizziness; Double-Blind Method; Female; Fentanyl; Humans; Hysterect

2022
Effect of additional equipotent fentanyl or sufentanil administration on recovery profiles during propofol-remifentanil-based anaesthesia in patients undergoing gynaecologic laparoscopic surgery: a randomized clinical trial.
    BMC anesthesiology, 2022, 04-29, Volume: 22, Issue:1

    Topics: Anesthesia; Delirium; Dizziness; Female; Fentanyl; Humans; Laparoscopy; Nausea; Propofol; Remifentan

2022
Comparison of IV dexketoprofen trometamol, fentanyl, and paracetamol in the treatment of renal colic in the ED: A randomized controlled trial.
    The American journal of emergency medicine, 2018, Volume: 36, Issue:4

    Topics: Acetaminophen; Administration, Intravenous; Adolescent; Adult; Aged; Analgesics; Anti-Inflammatory A

2018
An open-label randomised controlled trial on the efficacy of adding intranasal fentanyl to intravenous tramadol in patients with moderate to severe pain following acute musculoskeletal injuries.
    Singapore medical journal, 2017, Volume: 58, Issue:10

    Topics: Administration, Intranasal; Administration, Intravenous; Adolescent; Adult; Aged; Analgesics, Opioid

2017
Postoperative intravenous patient-controlled analgesia in thyroid surgery: comparison of fentanyl and ondansetron regimens with and without the nonsteriodal anti-inflammatory drug ketorolac.
    Thyroid : official journal of the American Thyroid Association, 2008, Volume: 18, Issue:12

    Topics: Adult; Analgesia, Patient-Controlled; Anti-Inflammatory Agents, Non-Steroidal; Dizziness; Female; Fe

2008
Modafinil reduces patient-reported tiredness after sedation/analgesia but does not improve patient psychomotor skills.
    Acta anaesthesiologica Scandinavica, 2010, Volume: 54, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesia; Anesthesia Recovery Period; Anesthetics, Inha

2010
Sublingual administration of fentanyl to cancer patients is an effective treatment for breakthrough pain: results from a randomized phase II study.
    Palliative medicine, 2010, Volume: 24, Issue:3

    Topics: Administration, Sublingual; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Cross-Ov

2010
Hearing loss after spinal anesthesia: the effect of different infusion solutions.
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2007, Volume: 137, Issue:1

    Topics: Anesthesia, Spinal; Audiometry, Pure-Tone; Auditory Threshold; Bupivacaine; Dizziness; Female; Fenta

2007
Bioequivalence following buccal and sublingual placement of fentanyl buccal tablet 400 microg in healthy subjects.
    Clinical drug investigation, 2008, Volume: 28, Issue:1

    Topics: Administration, Buccal; Administration, Sublingual; Adult; Analgesics, Opioid; Area Under Curve; Chr

2008
Oral transmucosal fentanyl citrate premedication in patients undergoing outpatient dermatologic procedures.
    The Journal of dermatologic surgery and oncology, 1994, Volume: 20, Issue:12

    Topics: Administration, Oral; Adult; Aged; Ambulatory Surgical Procedures; Anti-Anxiety Agents; Anxiety; Blo

1994
Can parturients distinguish between intravenous and epidural fentanyl?
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1994, Volume: 41, Issue:8

    Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Anesthesia, Epidural; Anesthesia, Intravenous; A

1994
Postoperative epidural fentanyl infusion--is the addition of 0.1% bupivacaine of benefit?
    Anaesthesia and intensive care, 1994, Volume: 22, Issue:1

    Topics: Abdominal Neoplasms; Adult; Aged; Analgesia, Epidural; Bupivacaine; Dizziness; Double-Blind Method;

1994
Postcesarean delivery epidural patient-controlled analgesia. Fentanyl or sufentanil?
    Anesthesiology, 1993, Volume: 78, Issue:3

    Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analgesia, Patient-Controlled; Bupivacaine; Cesa

1993
A comparison of recovery in outpatients receiving fentanyl versus those receiving butorphanol.
    Journal of clinical anesthesia, 1989, Volume: 1, Issue:5

    Topics: Adult; Anesthesia Recovery Period; Anesthesia, Intravenous; Butorphanol; Dizziness; Double-Blind Met

1989

Other Studies

5 other studies available for fentanyl and Dizziness

ArticleYear
Differential response to IV carfentanil in chronic cocaine users and healthy controls.
    Addiction biology, 2012, Volume: 17, Issue:1

    Topics: Adult; Analgesics, Opioid; Brain; Cocaine-Related Disorders; Dizziness; Female; Fentanyl; Half-Life;

2012
Advanced paediatric conscious sedation: an alternative to dental general anaesthetic in the U.K.
    SAAD digest, 2011, Volume: 27

    Topics: Adolescent; Anesthesia, Dental; Anesthetics, General; Anesthetics, Inhalation; Anesthetics, Intraven

2011
Postdischarge adverse events related to sedation for diagnostic imaging in children.
    Pediatric emergency care, 2012, Volume: 28, Issue:8

    Topics: Child; Child, Preschool; Dizziness; Female; Fentanyl; Follow-Up Studies; Humans; Hypnotics and Sedat

2012
Effect of CYP3A4*18B polymorphisms and interactions with OPRM1 A118G on postoperative fentanyl requirements in patients undergoing radical gastrectomy.
    Molecular medicine reports, 2013, Volume: 7, Issue:3

    Topics: Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Cytochrome P-450 CYP3A; Dizziness; F

2013
[Comparison of buprenorphine and fentanyl for postoperative pain relief by continuous epidural infusion].
    Masui. The Japanese journal of anesthesiology, 1993, Volume: 42, Issue:12

    Topics: Abdomen; Aged; Buprenorphine; Dizziness; Female; Fentanyl; Humans; Injections, Epidural; Male; Middl

1993