Page last updated: 2024-10-27

fentanyl and Disc, Herniated

fentanyl has been researched along with Disc, Herniated in 19 studies

Fentanyl: A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078)
fentanyl : A monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of N-phenyl-1-(2-phenylethyl)piperidin-4-amine with propanoic acid.

Research Excerpts

ExcerptRelevanceReference
" Demographic data, visual analog scale (VAS) and Quebec Back Pain Disability Scale (QBPDS) scores, mean arterial pressure (MAP) and heart rate (HR), total dosage of fentanyl, satisfaction rate of anesthesia and complications were collected at different timepoints."4.31Effect of intradiscal local anesthetic injection on intraoperative pain during percutaneous transforaminal endoscopic discectomy: A retrospective study. ( Duan, L; Kang, JY; Zhang, JH; Zhang, JY; Zhou, HC, 2023)
"The authors treated 9 patients receiving intradiscal electrothermal therapy who were unable to tolerate the latter portion of their heating protocol secondary to axial low back pain despite high doses of opioids, with low dose ketamine."3.72Sedation with ketamine during intradiscal electrothermal therapy. ( Cohen, SP; Larkin, T, 2004)
"An observer masked to the treatment assessed pain, pre- and postoperatively, with the Glasgow (GCPS), the Colorado (CPS) pain scales and a Visual Analogue Scale (VAS); additionally, the mechanical thresholds (MT) were measured with the Electronic von Frey Anaesthesiometer (EVF) at four points located near the herniated disc."2.94Use of acupuncture as adjuvant analgesic technique in dogs undergoing thoracolumbar hemilaminectomy. ( Adami, C; Machin, H; Taylor-Brown, F, 2020)
"Isoflurane was titrated to maintain sedation on the basis of a target bispectral index range of 40-60, and 25-microg increments of fentanyl were administered in response to increases in heart rate and systolic arterial blood pressure."2.71The effect of hemispheric synchronization on intraoperative analgesia. ( Lewis, AK; Osborn, IP; Roth, R, 2004)
" It may be assumed, that with partial agonists the relation of agonistic and antagonistic activity may be different, depending on the dosage used and on the respective pharmacologic effect observed during investigation."2.66[Intra- and postoperative interactions between the 2 opioids fentanyl and buprenorphine]. ( Börner, U; Gerlach, H; Gips, H; Hempelmann, G; Müller, H; Richter, M, 1986)
" Data obtained from the electronic medical records included primary outcomes (visual analog scale [VAS] scores and anesthesia satisfaction rate) and secondary outcomes, including vital signs such as heart rate (HR), mean arterial pressure (MAP), total dosage of fentanyl, operation time, X-ray exposure time, Oswestry Disability Index (ODI) scores, and complications."1.72Analgesic effect of epidural anesthesia via the intervertebral foramen approach in percutaneous transforaminal endoscopic discectomy: a retrospective study. ( Cai, Z; Kang, J; Liu, Y; Nie, C; Wang, X; Zhang, J; Zhou, H, 2022)
"To compare severity of postoperative pain in dogs undergoing hemilaminectomy because of acute thoracolumbar intervertebral disk disease treated with a combination of conventional analgesics and electroacupuncture (EAP) or with conventional analgesics alone."1.35Effects of adjunct electroacupuncture on severity of postoperative pain in dogs undergoing hemilaminectomy because of acute thoracolumbar intervertebral disk disease. ( Aeschbacher, G; Doherr, MG; Forterre, F; Glardon, O; Jaggy, A; Laim, A, 2009)
"Fentanyl caused little increase in the latencies of middle-latency-SEPs and of peak P2 of the VEPs."1.27[Effect of fentanyl and enflurane on sensory evoked potentials in the human in basic flunitrazepam/N2O anesthesia]. ( Pasch, T; Schramm, J; Thurner, F, 1987)
"However in the acute postoperative pain group other factors such as depletion of endorphins by drugs used for anesthesia or due to surgical stress cannot be excluded."1.26[Measurement of endorphins in human cerebrospinal fluid. Comparative study of various groups of patients]. ( Laorden, ML; Miralles, F; Olaso, MJ; Puig, MM, 1982)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19908 (42.11)18.7374
1990's2 (10.53)18.2507
2000's4 (21.05)29.6817
2010's1 (5.26)24.3611
2020's4 (21.05)2.80

Authors

AuthorsStudies
Lovell, S1
Simon, B1
Boudreau, EC1
Mankin, J1
Jeffery, N1
Duan, L1
Zhang, JY1
Zhang, JH1
Kang, JY1
Zhou, HC1
Zhang, J1
Wang, X1
Cai, Z1
Kang, J1
Liu, Y1
Nie, C1
Zhou, H1
Machin, H1
Taylor-Brown, F1
Adami, C1
Attari, MA1
Najafabadi, FM1
Talakoob, R1
Abrishamkar, S1
Taravati, H1
Laim, A1
Jaggy, A1
Forterre, F1
Doherr, MG1
Aeschbacher, G1
Glardon, O1
Wallenborn, J1
Rudolph, C1
Gelbrich, G1
Goerlich, TM1
Döhnert, J1
Dörner, J1
Olthoff, D1
Lewis, AK1
Osborn, IP1
Roth, R1
Cohen, SP1
Larkin, T1
Noury, D1
Lavenac, G1
Milon, D1
Sauvage, J1
Bodin, JM1
Saint-Marc, C1
Krumholz, W1
Müller, H2
Gerlach, H2
Russ, W1
Hempelmann, G3
Weidler, B1
von Bormann, B1
Seim, M1
Sturm, G1
Schwanen, N1
Laorden, ML1
Miralles, F1
Olaso, MJ1
Puig, MM1
Rainov, NG1
Gutjahr, T1
Burkert, W1
Striebel, HW1
Koenigs, D1
Krämer, J1
Gips, H1
Richter, M1
Börner, U1
Tommasino, C1
Scafuro, M1
Di Gregorio, AM1
Miele, E1
Cafaggi, G1
Thurner, F1
Schramm, J1
Pasch, T1
Shields, CB1
Arpin, EJ1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Prospective Study Comparing the Efficacy and Safety of 100 mcg and 200 mcg of Intranasal Fentanyl Pectin Spray as an Analgesic in Adult Males Undergoing Outpatient Cystoscopic Procedures[NCT01756651]Phase 120 participants (Actual)Interventional2013-02-28Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for fentanyl and Disc, Herniated

ArticleYear
Update on chymopapain.
    Neurologic clinics, 1985, Volume: 3, Issue:2

    Topics: Adolescent; Adult; Aged; Anaphylaxis; Anesthesia, Local; Causalgia; Cerebral Hemorrhage; Chymopapain

1985

Trials

8 trials available for fentanyl and Disc, Herniated

ArticleYear
Randomized clinical trial comparing outcomes after fentanyl or ketamine-dexmedetomidine analgesia in thoracolumbar spinal surgery in dogs.
    Journal of veterinary internal medicine, 2022, Volume: 36, Issue:5

    Topics: Analgesia; Analgesics, Opioid; Animals; Dexmedetomidine; Dog Diseases; Dogs; Fentanyl; Intervertebra

2022
Use of acupuncture as adjuvant analgesic technique in dogs undergoing thoracolumbar hemilaminectomy.
    Veterinary journal (London, England : 1997), 2020, Volume: 264

    Topics: Acupuncture Therapy; Analgesia; Analgesics, Opioid; Animals; Dog Diseases; Dogs; Fentanyl; Intervert

2020
Comparison of the Effects of 3 Methods of Intrathecal Bupivacaine, Bupivacaine-Fentanyl, and Bupivacaine-Fentanyl-Magnesium Sulfate on Sensory Motor Blocks and Postoperative Pain in Patients Undergoing Lumbar Disk Herniation Surgery.
    Journal of neurosurgical anesthesiology, 2016, Volume: 28, Issue:1

    Topics: Adult; Analgesics; Analgesics, Opioid; Anesthesia, Spinal; Anesthetics, Local; Bupivacaine; Double-B

2016
The effect of hemispheric synchronization on intraoperative analgesia.
    Anesthesia and analgesia, 2004, Volume: 98, Issue:2

    Topics: Analgesia; Anesthetics, Inhalation; Anesthetics, Intravenous; Blood Pressure; Cortical Synchronizati

2004
[Modified neuroleptanalgesia with buprenorphine].
    Anasthesie, Intensivtherapie, Notfallmedizin, 1982, Volume: 17, Issue:6

    Topics: Adult; Buprenorphine; Carbon Dioxide; Electrolytes; Female; Fentanyl; Heart Rate; Humans; Hydrocorti

1982
Intra-operative epidural morphine, fentanyl, and droperidol for control of pain after spinal surgery. A prospective, randomized, placebo-controlled, and double-blind trial.
    Acta neurochirurgica, 1996, Volume: 138, Issue:1

    Topics: Analgesia, Epidural; Analgesics, Opioid; Dose-Response Relationship, Drug; Double-Blind Method; Drop

1996
Postoperative pain management by intranasal demand-adapted fentanyl titration.
    Anesthesiology, 1992, Volume: 77, Issue:2

    Topics: Administration, Intranasal; Adult; Double-Blind Method; Female; Fentanyl; Humans; Injections, Intrav

1992
[Intra- and postoperative interactions between the 2 opioids fentanyl and buprenorphine].
    Der Anaesthesist, 1986, Volume: 35, Issue:4

    Topics: Acid-Base Equilibrium; Adrenocorticotropic Hormone; Anesthesia, General; Blood Pressure; Buprenorphi

1986

Other Studies

10 other studies available for fentanyl and Disc, Herniated

ArticleYear
Effect of intradiscal local anesthetic injection on intraoperative pain during percutaneous transforaminal endoscopic discectomy: A retrospective study.
    Asian journal of surgery, 2023, Volume: 46, Issue:7

    Topics: Anesthetics, Local; Back Pain; Diskectomy, Percutaneous; Fentanyl; Humans; Intervertebral Disc Displ

2023
Analgesic effect of epidural anesthesia via the intervertebral foramen approach in percutaneous transforaminal endoscopic discectomy: a retrospective study.
    BMC anesthesiology, 2022, 12-20, Volume: 22, Issue:1

    Topics: Anesthesia, Epidural; Diskectomy; Endoscopy; Fentanyl; Humans; Intervertebral Disc Displacement; Lum

2022
Effects of adjunct electroacupuncture on severity of postoperative pain in dogs undergoing hemilaminectomy because of acute thoracolumbar intervertebral disk disease.
    Journal of the American Veterinary Medical Association, 2009, May-01, Volume: 234, Issue:9

    Topics: Acute Disease; Analgesics, Opioid; Animals; Dog Diseases; Dogs; Electroacupuncture; Female; Fentanyl

2009
[Metoclopramide and dexamethasone in prevention of postoperative nausea and vomiting after inhalational anaesthesia].
    Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS, 2003, Volume: 38, Issue:11

    Topics: Adjuvants, Anesthesia; Adult; Aged; Anesthesia, Inhalation; Anesthetics, Inhalation; Antiemetics; De

2003
Sedation with ketamine during intradiscal electrothermal therapy.
    Spine, 2004, Jul-15, Volume: 29, Issue:14

    Topics: Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Back Pain; Conscious Sedation; Dose-Response Re

2004
[Neuroleptanalgesia for chemical nucleolysis].
    Cahiers d'anesthesiologie, 1984, Volume: 32, Issue:5

    Topics: Adult; Chymopapain; Droperidol; Endopeptidases; Female; Fentanyl; Humans; Intervertebral Disc Displa

1984
[A case of anaphylactoid reaction following administration of etomidate].
    Der Anaesthesist, 1984, Volume: 33, Issue:3

    Topics: Alcuronium; Anaphylaxis; Anesthesia, Inhalation; Drug Interactions; Etomidate; Fentanyl; Halothane;

1984
[Measurement of endorphins in human cerebrospinal fluid. Comparative study of various groups of patients].
    Revista espanola de fisiologia, 1982, Volume: 38, Issue:3

    Topics: Adult; Aged; Anesthetics; Animals; Biological Assay; Chronic Disease; Droperidol; Endorphins; Female

1982
[Rigidity caused by fentanyl during recovery from anesthesia. Description of a clinical case].
    Minerva anestesiologica, 1987, Volume: 53, Issue:5

    Topics: Adult; Anesthesia Recovery Period; Anesthesia, General; Fentanyl; Humans; Intervertebral Disc Displa

1987
[Effect of fentanyl and enflurane on sensory evoked potentials in the human in basic flunitrazepam/N2O anesthesia].
    Der Anaesthesist, 1987, Volume: 36, Issue:10

    Topics: Anesthesia, General; Dose-Response Relationship, Drug; Enflurane; Evoked Potentials, Auditory; Evoke

1987