fentanyl has been researched along with Delirium in 60 studies
Fentanyl: A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078)
fentanyl : A monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of N-phenyl-1-(2-phenylethyl)piperidin-4-amine with propanoic acid.
Delirium: A disorder characterized by CONFUSION; inattentiveness; disorientation; ILLUSIONS; HALLUCINATIONS; agitation; and in some instances autonomic nervous system overactivity. It may result from toxic/metabolic conditions or structural brain lesions. (From Adams et al., Principles of Neurology, 6th ed, pp411-2)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Fentanyl is associated with a higher incidence of hospital inpatient delirium when used for analgosedation compared with morphine, and the dose of opioid is linearly related to the need for antipsychotic medication administration." | 9.69 | Delirium in ventilated patients receiving fentanyl and morphine for Analgosedation: Findings from the ANALGESIC trial. ( Bellomo, R; Browne, E; Casamento, A; Chudleigh, L; Eastwood, GM; Lawrence, M; Neto, AS; Taplin, C, 2023) |
| " One patient in the propofol group developed delirium compared to zero in desflurane." | 9.24 | The effect of desflurane versus propofol anesthesia on postoperative delirium in elderly obese patients undergoing total knee replacement: A randomized, controlled, double-blinded clinical trial. ( Goodman, S; Huddleston, J; Lemmens, HJ; Maloney, W; Sommer, BR; Tanaka, P, 2017) |
| " In this study, 42 patients (American Society of Anesthesiology physical status I and II) who underwent scoliosis surgery were divided into two groups according to sedation protocols: group dexmedetomidine (DEX) (n = 22) and group midazolam (MDZ) (n = 20)." | 9.17 | Pain, fentanyl consumption, and delirium in adolescents after scoliosis surgery: dexmedetomidine vs midazolam. ( Aydogan, MS; Colak, C; Durmus, M; Erdogan, MA; Karaman, A; Korkmaz, MF; Ozgül, U; Togal, T; Yucel, A, 2013) |
| "In 99 patients receiving IV fentanyl, midazolam, or both, we evaluated drug doses, covariates likely to influence drug effects (age, body mass index, and renal and hepatic dysfunction); delirium risk factors; concomitant administration of CYP3A and P-glycoprotein substrates/inhibitors; ABCB1, ABCG2, and CYP3A5 genetic polymorphisms; and fentanyl and midazolam plasma levels." | 7.79 | Factors predisposing to coma and delirium: fentanyl and midazolam exposure; CYP3A5, ABCB1, and ABCG2 genetic polymorphisms; and inflammatory factors. ( Cossette, M; Leger, C; Michaud, V; Skrobik, Y; Turgeon, J, 2013) |
| "Dexmedetomidine may help to eliminate the emergence of agitation and can be a good treatment choice for the delirium state after cardiac surgery." | 7.77 | Dexmedetomidine in cardiac surgery patients who fail extubation and present with a delirium state. ( Aykac, Z; Can, Y; Coruh, T; Kehlibar, T; Ozler, A; Tarhan, A; Yapici, F; Yapici, N, 2011) |
| "We hypothesized that better methods of postoperative pain control would decrease postoperative delirium." | 6.70 | [Patient-controlled epidural analgesia with bupivacaine and fentanyl suppresses postoperative delirium following hepatectomy]. ( Kawamoto, M; Tanaka, H; Tokita, K; Yuge, O, 2001) |
| "Fentanyl is associated with a higher incidence of hospital inpatient delirium when used for analgosedation compared with morphine, and the dose of opioid is linearly related to the need for antipsychotic medication administration." | 5.69 | Delirium in ventilated patients receiving fentanyl and morphine for Analgosedation: Findings from the ANALGESIC trial. ( Bellomo, R; Browne, E; Casamento, A; Chudleigh, L; Eastwood, GM; Lawrence, M; Neto, AS; Taplin, C, 2023) |
| " Emergency surgery, more doses of midazolam, and fentanyl may be independent risk factors for SAD in mechanically ventilated patients with sepsis." | 5.34 | Incidence, risk factors, and outcomes for sepsis-associated delirium in patients with mechanical ventilation: A sub-analysis of a multicenter randomized controlled trial. ( Kawazoe, Y; Miyamoto, K; Mizobata, Y; Morimoto, T; Ohta, Y; Yamamoto, T; Yamamura, H, 2020) |
| " One patient in the propofol group developed delirium compared to zero in desflurane." | 5.24 | The effect of desflurane versus propofol anesthesia on postoperative delirium in elderly obese patients undergoing total knee replacement: A randomized, controlled, double-blinded clinical trial. ( Goodman, S; Huddleston, J; Lemmens, HJ; Maloney, W; Sommer, BR; Tanaka, P, 2017) |
| "The sedative effects of dexmedetomidine in the ICU patients treated with ventilator bundle treatment are satisfactory, and it can shorten the duration of mechanical ventilation, extubation time and length of ICU stay, reduce the incidence of delirium." | 5.20 | [A study of using dexmedetomidine in ventilator bundle treatment in an ICU]. ( Dong, C; Li, J; Song, R; Yang, J, 2015) |
| " In this study, 42 patients (American Society of Anesthesiology physical status I and II) who underwent scoliosis surgery were divided into two groups according to sedation protocols: group dexmedetomidine (DEX) (n = 22) and group midazolam (MDZ) (n = 20)." | 5.17 | Pain, fentanyl consumption, and delirium in adolescents after scoliosis surgery: dexmedetomidine vs midazolam. ( Aydogan, MS; Colak, C; Durmus, M; Erdogan, MA; Karaman, A; Korkmaz, MF; Ozgül, U; Togal, T; Yucel, A, 2013) |
| "In this double-blind, double-dummy study, there was no difference in the efficacy of intranasal fentanyl, IM and IV morphine in controlling postoperative pain and emergence delirium in children undergoing BMT placement." | 5.16 | Postoperative analgesic and behavioral effects of intranasal fentanyl, intravenous morphine, and intramuscular morphine in pediatric patients undergoing bilateral myringotomy and placement of ventilating tubes. ( Friedman, EM; Giannoni, C; Govindan, K; Hippard, HK; Larrier, D; Minard, CG; Sulek, M; Watcha, MF, 2012) |
| "In this post hoc analysis, larger doses of fentanyl administered intraoperatively and longer duration of mechanical ventilation were associated with postoperative delirium in the elderly after cardiac surgery." | 5.14 | Modifiable and nonmodifiable risk factors for postoperative delirium after cardiac surgery with cardiopulmonary bypass. ( Burkhart, CS; Dell-Kuster, S; Filipovic, M; Gamberini, M; Grapow, M; Moeckli, A; Monsch, AU; Seeberger, MD; Steiner, LA; Strebel, SP, 2010) |
| "Although recent studies suggest that opioid rotation could be an effective treatment strategy for morphine-induced delirium, there have been no prospective studies to investigate the treatment effects of opioid rotation using fentanyl." | 5.11 | Opioid rotation from morphine to fentanyl in delirious cancer patients: an open-label trial. ( Akechi, T; Ikenaga, M; Matsubara, T; Miyoshi, I; Morita, T; Onishi, H; Tajima, T; Takigawa, C; Tani, K; Uchitomi, Y, 2005) |
| " We evaluated doses of fentanyl, midazolam and clonidine, time of extubation, length of PICU stay and occurrence of withdrawal symptoms and delirium." | 4.12 | Sedation practices during high dose rate brachytherapy for children with urogenital and perianal rhabdomyosarcoma. ( Fuchs, J; Hofbeck, M; Kumpf, M; Michel, J; Neunhoeffer, F; Paulsen, F; Sauter, L; Schmidt, A, 2022) |
| "This study evaluated the difference in days alive without delirium or coma and the sedative requirements in patients receiving fentanyl versus hydromorphone in ECMO patients." | 3.96 | Comparison of Hydromorphone versus Fentanyl-based Sedation in Extracorporeal Membrane Oxygenation: A Propensity-Matched Analysis. ( Goméz, H; Harano, T; Landolf, KM; Murray, HN; Padmanabhan, RR; Rivosecchi, RM; Sanchez, PG; Sappington, PL; Sciortino, CM, 2020) |
| " Fentanyl (77%) and hydromorphone (48%) were the most common intravenous opioids used to manage pain." | 3.91 | Current practice and perceptions regarding pain, agitation and delirium management in patients receiving venovenous extracorporeal membrane oxygenation. ( Abrams, D; Agerstrand, C; Brodie, D; Dzierba, AL; Madahar, P; Muir, J, 2019) |
| "The incidence of delirium was compared among 114 patients who had started morphine, oxycodone, or fentanyl injection at Shizuoka Cancer Center between June 2012 and September 2014." | 3.85 | Incidence of Delirium Among Patients Having Cancer Injected With Different Opioids for the First Time. ( Ishikawa, H; Matsumoto, T; Mori, K; Omae, K; Osaka, I; Sato, T; Shino, M; Tanaka, R, 2017) |
| " Fentanyl, midazolam, and dexmedetomidine were the first choices of agents for analgesic, sedation, and delirium treatment." | 3.85 | A National Multicenter Survey on Management of Pain, Agitation, and Delirium in Intensive Care Units in China. ( Hu, B; Li, JG; Peng, ZY; Rao, X; Wang, J; Zhou, WH, 2017) |
| "Older age, higher SOFA score, regular smoking, and higher maintenance dose of midazolam and fentanyl when patients met sequential criteria were independent risk factors of delirium in sequential sedation patients." | 3.85 | Risk Factors of Delirium in Sequential Sedation Patients in Intensive Care Units. ( Kang, Y; Lv, Y; Wang, P; Wang, Z; Xu, B; Yang, J; Zhou, Y, 2017) |
| "In 99 patients receiving IV fentanyl, midazolam, or both, we evaluated drug doses, covariates likely to influence drug effects (age, body mass index, and renal and hepatic dysfunction); delirium risk factors; concomitant administration of CYP3A and P-glycoprotein substrates/inhibitors; ABCB1, ABCG2, and CYP3A5 genetic polymorphisms; and fentanyl and midazolam plasma levels." | 3.79 | Factors predisposing to coma and delirium: fentanyl and midazolam exposure; CYP3A5, ABCB1, and ABCG2 genetic polymorphisms; and inflammatory factors. ( Cossette, M; Leger, C; Michaud, V; Skrobik, Y; Turgeon, J, 2013) |
| "Dexmedetomidine may help to eliminate the emergence of agitation and can be a good treatment choice for the delirium state after cardiac surgery." | 3.77 | Dexmedetomidine in cardiac surgery patients who fail extubation and present with a delirium state. ( Aykac, Z; Can, Y; Coruh, T; Kehlibar, T; Ozler, A; Tarhan, A; Yapici, F; Yapici, N, 2011) |
| "Partial opioid substitution with fentanyl and moderate levels of hydration had no significant preventive effects on the occurrence of agitated delirium in the last week on a mass level." | 3.72 | Agitated terminal delirium and association with partial opioid substitution and hydration. ( Inoue, S; Morita, T; Tei, Y, 2003) |
| "Five cases of post narcotic delirium, somnolence or coma are interpreted as central anticholinergic syndromes as they were reversed by physostigmine." | 3.66 | [Physostigmine reversal of central anticholinergic syndrome induced by midazolam/fentanyl, benzoctamine/buprenorphine and etomidate/carticaine or by atropine/promethazine/pethidine for premedication? (author's transl)]. ( Jost, U; Ruppert, M; Schmid, A, 1982) |
| "The dosage of fentanyl-nefopam IV-PCA was significantly less in C group than R group for postoperative 24 h." | 3.11 | Effect of remifentanil on post-operative analgesic consumption in patients undergoing shoulder arthroplasty after interscalene brachial plexus block: a randomized controlled trial. ( Bae, H; Kim, JT; Kim, Y; Lim, YJ; Park, SK; Sakura, S; Yoo, S, 2022) |
| "The rates of respiratory depression (1." | 3.11 | Effect of additional equipotent fentanyl or sufentanil administration on recovery profiles during propofol-remifentanil-based anaesthesia in patients undergoing gynaecologic laparoscopic surgery: a randomized clinical trial. ( Huang, D; Huang, J; Jian, Q; Li, P; Ma, J; Xie, H; Zeng, W; Zhang, C, 2022) |
| "Fentanyl did not increase the incidence of severe adverse events (RR, 0." | 2.82 | Effects of fentanyl administration in mechanically ventilated patients in the intensive care unit: a systematic review and meta-analysis. ( Aoki, Y; Doi, M; Fujimura, N; Kato, H; Sakuraya, M; Suzuki, Y, 2022) |
| " (4) Compared with control group with the same sedative, the duration of mechanical ventilation, extubation time, length of ICU stay were significantly shortened, and the dosage of sedative drugs used was reduced in study group (all P < 0." | 2.82 | [Study of prevention and control of delirium in ventilated patients by simulating blockage of circadian rhythm with sedative in intensive care unit]. ( Dong, C; Feng, F; Li, J; Qi, Y; Song, R; Yang, J; Yang, Z; Zhang, H, 2016) |
| " The average Ramsay score, the frequency of propofol, the highest score of NRS, the total dosage of fentanyl and recovery time were compared." | 2.79 | [Sedative effects of dexmedetomidine in post-operative elder patients on mechanical ventilation]. ( Huang, F; Jin, J; Kong, J; Liu, S; Wang, J; Xu, H; Yang, X, 2014) |
| "Remifentanil hydrochloride is an ultra-short acting m-opioid receptor agonist." | 2.72 | Remifentanil vs fentanyl with a target controlled propofol infusion in patients undergoing craniotomy for supratentorial lesions. ( Ciritella, P; De Vivo, P; Del Gaudio, A; Lauta, E; Mastronardi, P; Perrotta, F; Puopolo, M, 2006) |
| "We hypothesized that better methods of postoperative pain control would decrease postoperative delirium." | 2.70 | [Patient-controlled epidural analgesia with bupivacaine and fentanyl suppresses postoperative delirium following hepatectomy]. ( Kawamoto, M; Tanaka, H; Tokita, K; Yuge, O, 2001) |
| " We rated the severity of AEs based on the Common Terminology Criteria for Adverse Events version 5." | 1.91 | Prevalence of opioid-induced adverse events across opioids commonly used for analgesic treatment in Japan: a multicenter prospective longitudinal study. ( Arakawa, S; Chiu, SW; Hiratsuka, Y; Hirayama, H; Inoue, A; Ishiki, H; Kosugi, K; Kubo, E; Matsuda, Y; Miyashita, M; Morita, T; Natsume, M; Nishijima, K; Ouchi, K; Sato, M; Satomi, E; Shigeno, T; Shimizu, M; Shimoda, M; Shimoi, T; Tagami, K; Yamaguchi, T; Yokomichi, N, 2023) |
| "Ketamine was used for 33." | 1.72 | Safety and feasibility of continuous ketamine infusion for analgosedation in medical and cardiac ICU patients who received mechanical ventilation support: A retrospective cohort study. ( Ahn, HY; Chung, CR; Jung, H; Ko, RE; Lee, J; Suh, GY; Yang, JH, 2022) |
| "Propofol and fentanyl were the sedative agents of choice in the early and late periods, respectively." | 1.56 | Singapore SPICE: sedation practices in intensive care evaluation in Singapore - a prospective cohort study of the public healthcare system. ( Bailey, MJ; Chia, N; Ho, BCH; Kalyanasundaram, G; Lim, D; Mukhopadhyay, A; Ng, SY; Phua, J; Shehabi, Y; Ti, LK; Wong, YL, 2020) |
| "Infant delirium is an under-recognized clinical entity in neonatal intensive care, and earlier identification and treatment could minimize morbidities associated with this condition." | 1.46 | A case of infant delirium in the neonatal intensive care unit. ( Bidegain, M; Cotten, CM; Edwards, LE; Hornik, CD; Hutchison, LB; Smith, PB, 2017) |
| "Propofol (89%) use was common, followed by midazolam (49%)." | 1.42 | A web-based survey of United Kingdom sedation practice in the intensive care unit. ( McKenzie, CA; Terblanche, M; Yassin, J; Yassin, SM, 2015) |
| "To determine the dosing patterns and total doses of fentanyl, lorazepam, and haloperidol according to nursing shift in a cohort of older patients in a medical intensive care unit." | 1.39 | Patterns of opiate, benzodiazepine, and antipsychotic drug dosing in older patients in a medical intensive care unit. ( Akgün, KM; Araujo, KL; Bramley, K; Murphy, TE; Pisani, MA; Vest, MT, 2013) |
| "ICU-delirium is common and occurred in all age groups in the present study." | 1.35 | [Incidence of intensive care unit delirium]. ( Svenningsen, H; Tønnesen, E, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (6.67) | 18.7374 |
| 1990's | 4 (6.67) | 18.2507 |
| 2000's | 13 (21.67) | 29.6817 |
| 2010's | 28 (46.67) | 24.3611 |
| 2020's | 11 (18.33) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, C | 1 |
| Huang, D | 1 |
| Zeng, W | 1 |
| Ma, J | 1 |
| Li, P | 1 |
| Jian, Q | 1 |
| Huang, J | 1 |
| Xie, H | 1 |
| Kim, Y | 1 |
| Bae, H | 1 |
| Yoo, S | 1 |
| Park, SK | 1 |
| Lim, YJ | 1 |
| Sakura, S | 1 |
| Kim, JT | 2 |
| Jung, H | 1 |
| Lee, J | 1 |
| Ahn, HY | 1 |
| Yang, JH | 1 |
| Suh, GY | 1 |
| Ko, RE | 1 |
| Chung, CR | 1 |
| Aoki, Y | 1 |
| Kato, H | 1 |
| Fujimura, N | 1 |
| Suzuki, Y | 1 |
| Sakuraya, M | 1 |
| Doi, M | 1 |
| Casamento, A | 1 |
| Neto, AS | 1 |
| Lawrence, M | 1 |
| Chudleigh, L | 1 |
| Browne, E | 1 |
| Taplin, C | 1 |
| Eastwood, GM | 1 |
| Bellomo, R | 1 |
| Hiratsuka, Y | 1 |
| Tagami, K | 1 |
| Inoue, A | 1 |
| Sato, M | 1 |
| Matsuda, Y | 1 |
| Kosugi, K | 1 |
| Kubo, E | 1 |
| Natsume, M | 1 |
| Ishiki, H | 1 |
| Arakawa, S | 1 |
| Shimizu, M | 1 |
| Yokomichi, N | 1 |
| Chiu, SW | 1 |
| Shimoda, M | 1 |
| Hirayama, H | 1 |
| Nishijima, K | 1 |
| Ouchi, K | 1 |
| Shimoi, T | 1 |
| Shigeno, T | 1 |
| Yamaguchi, T | 1 |
| Miyashita, M | 1 |
| Morita, T | 3 |
| Satomi, E | 1 |
| Hao, J | 1 |
| Dong, B | 1 |
| Zhang, J | 2 |
| Luo, Z | 1 |
| Yamamoto, T | 1 |
| Mizobata, Y | 1 |
| Kawazoe, Y | 1 |
| Miyamoto, K | 1 |
| Ohta, Y | 1 |
| Morimoto, T | 1 |
| Yamamura, H | 1 |
| Landolf, KM | 1 |
| Rivosecchi, RM | 1 |
| Goméz, H | 1 |
| Sciortino, CM | 1 |
| Murray, HN | 1 |
| Padmanabhan, RR | 1 |
| Sanchez, PG | 1 |
| Harano, T | 1 |
| Sappington, PL | 1 |
| Bastos, AS | 1 |
| Beccaria, LM | 1 |
| Silva, DCD | 1 |
| Barbosa, TP | 1 |
| Michel, J | 1 |
| Sauter, L | 1 |
| Neunhoeffer, F | 1 |
| Hofbeck, M | 1 |
| Kumpf, M | 1 |
| Paulsen, F | 1 |
| Schmidt, A | 1 |
| Fuchs, J | 1 |
| Wang, J | 2 |
| Peng, ZY | 1 |
| Zhou, WH | 1 |
| Hu, B | 1 |
| Rao, X | 1 |
| Li, JG | 1 |
| Tanaka, P | 1 |
| Goodman, S | 1 |
| Sommer, BR | 1 |
| Maloney, W | 1 |
| Huddleston, J | 1 |
| Lemmens, HJ | 1 |
| Yang, J | 3 |
| Zhou, Y | 1 |
| Kang, Y | 1 |
| Xu, B | 1 |
| Wang, P | 1 |
| Lv, Y | 1 |
| Wang, Z | 1 |
| Ng, SY | 1 |
| Phua, J | 1 |
| Wong, YL | 1 |
| Kalyanasundaram, G | 1 |
| Mukhopadhyay, A | 1 |
| Lim, D | 1 |
| Chia, N | 1 |
| Ho, BCH | 1 |
| Bailey, MJ | 1 |
| Shehabi, Y | 1 |
| Ti, LK | 1 |
| Dzierba, AL | 1 |
| Abrams, D | 1 |
| Madahar, P | 1 |
| Muir, J | 1 |
| Agerstrand, C | 1 |
| Brodie, D | 1 |
| Aydogan, MS | 1 |
| Korkmaz, MF | 1 |
| Ozgül, U | 1 |
| Erdogan, MA | 1 |
| Yucel, A | 1 |
| Karaman, A | 1 |
| Togal, T | 1 |
| Durmus, M | 1 |
| Colak, C | 1 |
| Pisani, MA | 1 |
| Bramley, K | 1 |
| Vest, MT | 1 |
| Akgün, KM | 1 |
| Araujo, KL | 1 |
| Murphy, TE | 1 |
| Patel, SB | 2 |
| Poston, JT | 1 |
| Pohlman, A | 1 |
| Hall, JB | 2 |
| Kress, JP | 2 |
| Takala, J | 2 |
| Ely, EW | 1 |
| Pandharipande, PP | 1 |
| Hughes, CG | 1 |
| Girard, TD | 1 |
| Yassin, SM | 1 |
| Terblanche, M | 1 |
| Yassin, J | 1 |
| McKenzie, CA | 1 |
| Huang, F | 1 |
| Yang, X | 1 |
| Xu, H | 1 |
| Kong, J | 1 |
| Liu, S | 2 |
| Jin, J | 1 |
| Jiang, L | 1 |
| Ding, S | 1 |
| Yan, H | 1 |
| Li, Y | 1 |
| Zhang, L | 1 |
| Chen, X | 1 |
| Yin, X | 1 |
| Tang, X | 1 |
| Li, J | 2 |
| Dong, C | 2 |
| Zhang, H | 2 |
| Song, R | 2 |
| Yang, Z | 1 |
| Feng, F | 1 |
| Qi, Y | 1 |
| Song, IK | 1 |
| Park, YH | 1 |
| Lee, JH | 1 |
| Choi, IH | 1 |
| Kim, HS | 1 |
| Tanaka, R | 1 |
| Ishikawa, H | 1 |
| Sato, T | 1 |
| Shino, M | 1 |
| Matsumoto, T | 1 |
| Mori, K | 1 |
| Omae, K | 1 |
| Osaka, I | 1 |
| Gagnon, DJ | 1 |
| Fontaine, GV | 1 |
| Smith, KE | 1 |
| Riker, RR | 1 |
| Miller, RR | 1 |
| Lerwick, PA | 1 |
| Lucas, FL | 1 |
| Dziodzio, JT | 1 |
| Sihler, KC | 1 |
| Fraser, GL | 1 |
| Edwards, LE | 1 |
| Hutchison, LB | 1 |
| Hornik, CD | 1 |
| Smith, PB | 1 |
| Cotten, CM | 1 |
| Bidegain, M | 1 |
| Shiiba, M | 1 |
| Takei, M | 1 |
| Nakatsuru, M | 1 |
| Bukawa, H | 1 |
| Yokoe, H | 1 |
| Uzawa, K | 1 |
| Tanzawa, H | 1 |
| Svenningsen, H | 1 |
| Tønnesen, E | 1 |
| Burkhart, CS | 1 |
| Dell-Kuster, S | 1 |
| Gamberini, M | 1 |
| Moeckli, A | 1 |
| Grapow, M | 1 |
| Filipovic, M | 1 |
| Seeberger, MD | 1 |
| Monsch, AU | 1 |
| Strebel, SP | 1 |
| Steiner, LA | 1 |
| Chen, J | 1 |
| Li, W | 1 |
| Hu, X | 1 |
| Wang, D | 1 |
| Yapici, N | 1 |
| Coruh, T | 1 |
| Kehlibar, T | 1 |
| Yapici, F | 1 |
| Tarhan, A | 1 |
| Can, Y | 1 |
| Ozler, A | 1 |
| Aykac, Z | 1 |
| Bilotta, F | 1 |
| Doronzio, A | 1 |
| Stazi, E | 1 |
| Titi, L | 1 |
| Zeppa, IO | 1 |
| Cianchi, A | 1 |
| Rosa, G | 1 |
| Paoloni, FP | 1 |
| Bergese, S | 1 |
| Asouhidou, I | 1 |
| Ioannou, P | 1 |
| Abramowicz, AE | 1 |
| Spinelli, A | 1 |
| Delphin, E | 1 |
| Ayrian, E | 1 |
| Zelman, V | 1 |
| Lumb, P | 1 |
| Hippard, HK | 1 |
| Govindan, K | 1 |
| Friedman, EM | 1 |
| Sulek, M | 1 |
| Giannoni, C | 1 |
| Larrier, D | 1 |
| Minard, CG | 1 |
| Watcha, MF | 1 |
| Skrobik, Y | 1 |
| Leger, C | 1 |
| Cossette, M | 1 |
| Michaud, V | 1 |
| Turgeon, J | 1 |
| Grace, RF | 1 |
| Tei, Y | 1 |
| Inoue, S | 1 |
| Micek, ST | 1 |
| Anand, NJ | 1 |
| Laible, BR | 1 |
| Shannon, WD | 1 |
| Kollef, MH | 1 |
| Takigawa, C | 1 |
| Onishi, H | 1 |
| Tajima, T | 1 |
| Tani, K | 1 |
| Matsubara, T | 1 |
| Miyoshi, I | 1 |
| Ikenaga, M | 1 |
| Akechi, T | 1 |
| Uchitomi, Y | 1 |
| Del Gaudio, A | 1 |
| Ciritella, P | 1 |
| Perrotta, F | 1 |
| Puopolo, M | 1 |
| Lauta, E | 1 |
| Mastronardi, P | 1 |
| De Vivo, P | 1 |
| van Rijswijk, R | 1 |
| van Guldener, C | 1 |
| Jost, U | 1 |
| Schmid, A | 1 |
| Ruppert, M | 1 |
| Crawford, RD | 1 |
| Baskoff, JD | 1 |
| Kuzma, PJ | 1 |
| Kline, MD | 1 |
| Stamatos, JM | 1 |
| Auth, DA | 1 |
| Link, J | 1 |
| Weiss, AP | 1 |
| Murray, GB | 1 |
| del Rosario, MA | 1 |
| Feria, M | 1 |
| Martín, AS | 1 |
| Ortega, JJ | 1 |
| del Castillo, LP | 1 |
| Vielvoye-Kerkmeer, AP | 1 |
| van der Weide, M | 1 |
| Tokita, K | 1 |
| Tanaka, H | 1 |
| Kawamoto, M | 1 |
| Yuge, O | 1 |
| Granberg Axèll, AI | 1 |
| Malmros, CW | 1 |
| Bergbom, IL | 1 |
| Lundberg, DB | 1 |
| Steinberg, RB | 1 |
| Gilman, DE | 1 |
| Johnson, F | 1 |
| Williams-Russo, P | 1 |
| Urquhart, BL | 1 |
| Sharrock, NE | 1 |
| Charlson, ME | 1 |
| Weinger, MB | 1 |
| Swerdlow, NR | 1 |
| Millar, WL | 1 |
| Coppel, DL | 1 |
| Bovill, JG | 1 |
| Dundee, JW | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized Controlled Trial to Evaluate the Impact of Integrated Preoperative Fascia Iliaca Compartment Block (FICB) for Fast-track Surgery in Elderly Hip Fracture[NCT05857462] | 420 participants (Anticipated) | Interventional | 2023-05-31 | Recruiting | |||
| Modified Hospital Elder Life Program at Intensive Care Unit: A Stepped-Wedge Cluster Randomized Controlled Trial[NCT06054828] | 266 participants (Anticipated) | Interventional | 2023-09-05 | Recruiting | |||
| A Survey of Management of Analgesia, Sedation and Delirium in ICU Patients in China[NCT04217915] | 800 participants (Anticipated) | Observational | 2021-07-12 | Recruiting | |||
| Effect of Flumazenil on Hypoactive Delirium in the ICU: A Double-Blind, Placebo-Controlled Pilot Study[NCT02899156] | Phase 4 | 22 participants (Actual) | Interventional | 2016-03-31 | Terminated (stopped due to A planned interim analysis led to the trial being stopped early based on the observed size effect and power analysis.) | ||
| An Assessment of Delirium in Mechanically Ventilated Patients Undergoing Daily Awakening From Sedation[NCT00919698] | 102 participants (Actual) | Observational | 2010-06-30 | Completed | |||
| Perioperative Multimodal General Anesthesia Focusing on Specific CNS Targets in Patients Undergoing Cardiac Surgeries[NCT04016740] | Early Phase 1 | 22 participants (Actual) | Interventional | 2019-08-20 | Completed | ||
| Impact of Dexmedetomidine on the Incidence of Postoperative Delirium in Patients After Cardiac Surgery: a Randomized, Double-blinded, and Placebo-controlled Clinical Trial[NCT02267538] | Phase 4 | 285 participants (Actual) | Interventional | 2014-11-30 | Completed | ||
| [NCT01506622] | 222 participants (Actual) | Interventional | 2011-01-31 | Completed | |||
| Effect of Clonidine vs. Dexmedetomidine in Addition to Standard Treatment in Agitated Delirium in Intensive Care Patients: Pilot Study.[NCT04758936] | Phase 4 | 50 participants (Anticipated) | Interventional | 2021-02-01 | Recruiting | ||
| Post Operative Cognitive Recovery and Neuropsychological Complications After General Anesthesia. A Comparison Between Different Techniques of Anesthesia: A Multi-Center Observational Study[NCT00507195] | 1,200 participants (Anticipated) | Observational | 2007-05-31 | Recruiting | |||
| Postoperative Analgesic and Behavioral Effects of Intranasal Fentanyl, Intravenous Morphine and Intramuscular Morphine in Pediatric Patients Undergoing Bilateral Myringotomy and Placement of Ventilating Tubes[NCT01244126] | Phase 4 | 171 participants (Actual) | Interventional | 2008-05-31 | Completed | ||
| Risk Factors for Delirium in Critically Ill Surgical Patients[NCT03050021] | 251 participants (Actual) | Observational | 2013-04-01 | Completed | |||
| Awakening-Breathing Coordination, Delirium Monitoring/Management & Early Mobility (ABCDE) Protocol[NCT01413009] | 200 participants (Actual) | Observational | 2010-12-29 | Completed | |||
| Anesthesiological Strategies in Elective Craniotomy: Randomized, Equivalence, Open Trial[NCT00741351] | Phase 3 | 411 participants (Actual) | Interventional | 2007-12-31 | Completed | ||
| Prevention of Nicotine Abstinence in Critically Ill Patients After Major Surgery[NCT03847155] | 52 participants (Actual) | Interventional | 2015-09-23 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
average duration of time patient was randomized to each infusion up to 72 hours (NCT02899156)
Timeframe: up to 72 hours after the start of the infusion
| Intervention | hours (Mean) |
|---|---|
| Flumazenil Group | 54.8 |
| Placebo Group | 58.2 |
average maximum rate (ml/hr) during the 72 hours after study infusion (NCT02899156)
Timeframe: up to 72 hours after the start of the infusion
| Intervention | milliliters per hour (Mean) |
|---|---|
| Flumazenil Group | 5 |
| Placebo Group | 5.2 |
length of time that the patient was admitted to an intensive care unit service during the hospital stay (NCT02899156)
Timeframe: duration of admission to the intensive care unit
| Intervention | days (Mean) |
|---|---|
| Flumazenil Group | 7.8 |
| Placebo Group | 7 |
Defined by the number of days in the 14-day period after randomization that the patient was alive and not delirious (i.e. CAM-ICU negative). Zero delirium-free days will be observed for patients that die within the 14-day period. (NCT02899156)
Timeframe: up to 14 days after randomization
| Intervention | days (Median) |
|---|---|
| Flumazenil Group | 12.7 |
| Placebo Group | 9.2 |
number of days within the first 28 days after enrollment that the patient was free from needing mechanical ventilation (NCT02899156)
Timeframe: up to 28 days after randomization
| Intervention | days (Mean) |
|---|---|
| Flumazenil Group | 23.6 |
| Placebo Group | 24.9 |
defined by the proportion of patients who were delirium free at 14 days after randomization (NCT02899156)
Timeframe: up to 14 days after randomization
| Intervention | Participants (Count of Participants) |
|---|---|
| Flumazenil Group | 9 |
| Placebo Group | 7 |
number of times that a RASS score of + 2 to +4 occurred that did not resolve with decreasing study infusion (NCT02899156)
Timeframe: up to 72 hours after the start of the infusion
| Intervention | Participants (Count of Participants) |
|---|---|
| Flumazenil Group | 0 |
| Placebo Group | 0 |
Delirium was assessed with the Confusion Assessment Method for the Intensive Care Unit (CAM-ICU) twice daily during the first five days after surgery. (NCT02267538)
Timeframe: During the first five days after surgery
| Intervention | Participants (Count of Participants) |
|---|---|
| DEX Group | 7 |
| CTRL Group | 11 |
Results was presented as median (95% confidence interval). (NCT02267538)
Timeframe: From end of surgery until discharge from hospital or 30 days after surgery
| Intervention | days (Median) |
|---|---|
| DEX Group | 9 |
| CTRL Group | 9 |
Results was presented as median (95% confidence interval). (NCT02267538)
Timeframe: From end of surgery until discharge from Intensive Care Unit or 30 days after surgery
| Intervention | hours (Median) |
|---|---|
| DEX Group | 45.0 |
| CTRL Group | 46.0 |
"Cognitive function was assessed with the Mini Mental State Examination (MMSE) at baseline (the day before surgery) and on the sixth day after surgery, and with modified telephone interview for cognitive status (m-TICS) on the 30th day after surgery.~The introduction of MMSE scale has been explained in the baseline part in the result section.~The Telephone Interview for Cognitive Status-modified scale(m-TICS) is one of the most popular telephone interview-based screening instruments for mild cognitive impairment and dementia. It consists 11 items including wordlist memory, orientation, attention, repetition, conceptual knowledge and nonverbal praxis, which score ranges from 0 to 48, with higher scores indicating better cognitive function" (NCT02267538)
Timeframe: on the sixth day after surgery, and on the 30th day after surgery
| Intervention | units on a scale (Median) | |
|---|---|---|
| MMSE score on postoperative day 6 | m-TICS score on postoperative day 30 | |
| CTRL Group | 29 | 34 |
| DEX Group | 29 | 34 |
Non-delirium complications was defined as any conditions other than delirium that occurred during the first 30 days after surgery and required therapeutic intervention.Complications listed here were not considered adverse events in this study. (NCT02267538)
Timeframe: Occurrence of non-delirium complications will be monitored until 30 days after surgery.
| Intervention | Participants (Count of Participants) | |||||||
|---|---|---|---|---|---|---|---|---|
| Stroke | New onset arrythmia | Pulmonary complications | Upper gastrointestinal bleeding | Surgical bleeding | Wound dehiscence or infection | Acute kidney injury | IABP assistance | |
| CTRL Group | 3 | 51 | 27 | 4 | 3 | 7 | 44 | 12 |
| DEX Group | 3 | 42 | 15 | 2 | 3 | 11 | 37 | 6 |
Pain intensity was assessed daily at 8 am during the first five days after surgery with the Numeric Rating Scale (NRS, 0 = no pain, 10 = the worst possible pain). (NCT02267538)
Timeframe: During the first five days after surgery
| Intervention | units on a scale (Median) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Pain score after surgery(d1), at rest | Pain score after surgery(d2), at rest | Pain score after surgery(d3), at rest | Pain score after surgery(d4), at rest | Pain score after surgery(d5), at rest | Pain score after surgery(d1), with coughing | Pain score after surgery(d2), with coughing | Pain score after surgery(d3), with coughing | Pain score after surgery(d4), with coughing | Pain score after surgery(d5), with coughing | |
| CTRL Group | 3 | 3 | 2 | 2 | 1 | 4 | 4 | 4 | 3 | 2 |
| DEX Group | 3 | 4 | 3 | 2 | 2 | 4 | 5 | 4 | 3 | 2 |
Subjective sleep quality was assessed daily at 8 am during the first five days after surgery with the Numeric Rating Scale (NRS, 0 = best sleep, 10 = the worst possible sleep). (NCT02267538)
Timeframe: During the first five days after surgery
| Intervention | units on a scale (Median) | ||||
|---|---|---|---|---|---|
| Subjective sleep quality after surgery(d1), score | Subjective sleep quality after surgery(d2), score | Subjective sleep quality after surgery(d3), score | Subjective sleep quality after surgery(d4), score | Subjective sleep quality after surgery(d5), score | |
| CTRL Group | 2 | 3 | 2 | 2 | 2 |
| DEX Group | 2 | 3 | 2 | 2 | 2 |
"Maximum score on the Pediatric Anesthesia Emergence delirium scale. This has 5 items ranging from 1-4 and higher scores indicate greater emergence delirium.~1. eye contact with care giver ,score 1-4, purposeful actions 1-4, aware of surrounding 1-4,restless 1-4, inconsolable 1-4, Maximum score 20." (NCT01244126)
Timeframe: Upon arrival in the PACU, and at 5, 10, 15, 30, 45, 60 minutes and at discharge
| Intervention | units on a scale (Mean) |
|---|---|
| IM Morphine | 6.1 |
| IV Morphine | 6.3 |
| Fentanyl IN | 4.6 |
FLACC assigns 0-2 points for each of 5 categories (face, legs, activity, cry, consolability)and sums these points to give a total score where high scores indicate worse pain (Paediatr Anaesth 2006; 16: 258-65) (NCT01244126)
Timeframe: Upon arrival in the PACU, and at 5, 10, 15, 30, 45, 60 minutes and at discharge
| Intervention | units on a scale (Mean) |
|---|---|
| IM Morphine | 2.9 |
| IV Morphine | 2.7 |
| Fentanyl IN | 2.0 |
1 review available for fentanyl and Delirium
| Article | Year |
|---|---|
Effects of fentanyl administration in mechanically ventilated patients in the intensive care unit: a systematic review and meta-analysis.
Topics: Analgesics, Opioid; Delirium; Fentanyl; Humans; Intensive Care Units; Morphine Derivatives; Remifent | 2022 |
21 trials available for fentanyl and Delirium
| Article | Year |
|---|---|
Effect of additional equipotent fentanyl or sufentanil administration on recovery profiles during propofol-remifentanil-based anaesthesia in patients undergoing gynaecologic laparoscopic surgery: a randomized clinical trial.
Topics: Anesthesia; Delirium; Dizziness; Female; Fentanyl; Humans; Laparoscopy; Nausea; Propofol; Remifentan | 2022 |
Effect of remifentanil on post-operative analgesic consumption in patients undergoing shoulder arthroplasty after interscalene brachial plexus block: a randomized controlled trial.
Topics: Analgesics; Analgesics, Opioid; Arthroplasty, Replacement, Shoulder; Brachial Plexus Block; Delirium | 2022 |
Delirium in ventilated patients receiving fentanyl and morphine for Analgosedation: Findings from the ANALGESIC trial.
Topics: Analgesics; Analgesics, Opioid; Antipsychotic Agents; Delirium; Fentanyl; Humans; Morphine; Respirat | 2023 |
Pre-emptive analgesia with continuous fascia iliaca compartment block reduces postoperative delirium in elderly patients with hip fracture. A randomized controlled trial.
Topics: Aged; Analgesia, Epidural; Analgesics, Opioid; Anesthetics, Local; Delirium; Double-Blind Method; Fe | 2019 |
Incidence, risk factors, and outcomes for sepsis-associated delirium in patients with mechanical ventilation: A sub-analysis of a multicenter randomized controlled trial.
Topics: Aged; Aged, 80 and over; Critical Care; Delirium; Female; Fentanyl; Hospital Mortality; Humans; Hypn | 2020 |
The effect of desflurane versus propofol anesthesia on postoperative delirium in elderly obese patients undergoing total knee replacement: A randomized, controlled, double-blinded clinical trial.
Topics: Aged; Anesthesia, General; Arthroplasty, Replacement, Knee; Cognitive Dysfunction; Delirium; Desflur | 2017 |
Pain, fentanyl consumption, and delirium in adolescents after scoliosis surgery: dexmedetomidine vs midazolam.
Topics: Adolescent; Analgesics, Opioid; Anesthesia, General; Arterial Pressure; Child; Conscious Sedation; C | 2013 |
[Sedative effects of dexmedetomidine in post-operative elder patients on mechanical ventilation].
Topics: Aged; Analgesics; Delirium; Dexmedetomidine; Fentanyl; Humans; Hypnotics and Sedatives; Intensive Ca | 2014 |
[Study of prevention and control of delirium in ventilated patients by simulating blockage of circadian rhythm with sedative in intensive care unit].
Topics: Analgesics; Circadian Rhythm; Critical Care; Delirium; Dexmedetomidine; Fentanyl; Humans; Hypnotics | 2016 |
Randomized controlled trial on preemptive analgesia for acute postoperative pain management in children.
Topics: Acute Pain; Administration, Intravenous; Analgesia; Analgesia, Patient-Controlled; Analgesics, Opioi | 2016 |
[A study of using dexmedetomidine in ventilator bundle treatment in an ICU].
Topics: Arterial Pressure; Blood Pressure; Delirium; Dexmedetomidine; Fentanyl; Humans; Hypnotics and Sedati | 2015 |
Modifiable and nonmodifiable risk factors for postoperative delirium after cardiac surgery with cardiopulmonary bypass.
Topics: Aged; Aged, 80 and over; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Delirium; Female; Fent | 2010 |
Modifiable and nonmodifiable risk factors for postoperative delirium after cardiac surgery with cardiopulmonary bypass.
Topics: Aged; Aged, 80 and over; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Delirium; Female; Fent | 2010 |
Modifiable and nonmodifiable risk factors for postoperative delirium after cardiac surgery with cardiopulmonary bypass.
Topics: Aged; Aged, 80 and over; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Delirium; Female; Fent | 2010 |
Modifiable and nonmodifiable risk factors for postoperative delirium after cardiac surgery with cardiopulmonary bypass.
Topics: Aged; Aged, 80 and over; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Delirium; Female; Fent | 2010 |
Emergence agitation after cataract surgery in children: a comparison of midazolam, propofol and ketamine.
Topics: Anesthesia Recovery Period; Anesthesia, General; Anesthetics, Dissociative; Anesthetics, Inhalation; | 2010 |
Early postoperative cognitive dysfunction and postoperative delirium after anaesthesia with various hypnotics: study protocol for a randomised controlled trial--the PINOCCHIO trial.
Topics: Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Cognition; Cognition Disorde | 2011 |
Postoperative analgesic and behavioral effects of intranasal fentanyl, intravenous morphine, and intramuscular morphine in pediatric patients undergoing bilateral myringotomy and placement of ventilating tubes.
Topics: Administration, Intranasal; Age Factors; Analgesics, Opioid; Anesthesia Recovery Period; Chest Tubes | 2012 |
The effect of variable-dose diazepam on dreaming and emergence phenomena in 400 cases of ketamine-fentanyl anaesthesia.
Topics: Adjuvants, Anesthesia; Adult; Anesthesia Recovery Period; Anesthetics, Combined; Anesthetics, Dissoc | 2003 |
Opioid rotation from morphine to fentanyl in delirious cancer patients: an open-label trial.
Topics: Aged; Analgesics, Opioid; Delirium; Dose-Response Relationship, Drug; Drug Administration Schedule; | 2005 |
Remifentanil vs fentanyl with a target controlled propofol infusion in patients undergoing craniotomy for supratentorial lesions.
Topics: Adult; Aged; Anesthesia Recovery Period; Anesthesia, Intravenous; Anesthetics, Intravenous; Cranioto | 2006 |
[Patient-controlled epidural analgesia with bupivacaine and fentanyl suppresses postoperative delirium following hepatectomy].
Topics: Aged; Analgesia, Epidural; Bupivacaine; Delirium; Female; Fentanyl; Hepatectomy; Humans; Male; Mepiv | 2001 |
Post-operative delirium: predictors and prognosis in elderly orthopedic patients.
Topics: Age Factors; Aged; Aged, 80 and over; Alcohol Drinking; Analgesia, Epidural; Bupivacaine; Comorbidit | 1992 |
The taming of ketamine.
Topics: Adjuvants, Anesthesia; Adult; Anesthesia, Intravenous; Atropine; Delirium; Diazepam; Dreams; Droperi | 1973 |
38 other studies available for fentanyl and Delirium
| Article | Year |
|---|---|
Safety and feasibility of continuous ketamine infusion for analgosedation in medical and cardiac ICU patients who received mechanical ventilation support: A retrospective cohort study.
Topics: Adult; Analgesics; Analgesics, Opioid; Antipsychotic Agents; Delirium; Feasibility Studies; Fentanyl | 2022 |
Prevalence of opioid-induced adverse events across opioids commonly used for analgesic treatment in Japan: a multicenter prospective longitudinal study.
Topics: Analgesics, Opioid; Cancer Pain; Constipation; Delirium; Fentanyl; Humans; Hydromorphone; Japan; Lon | 2023 |
Comparison of Hydromorphone versus Fentanyl-based Sedation in Extracorporeal Membrane Oxygenation: A Propensity-Matched Analysis.
Topics: Adult; Delirium; Extracorporeal Membrane Oxygenation; Female; Fentanyl; Humans; Hydromorphone; Hypno | 2020 |
Prevalence of delirium in intensive care patients and association with sedoanalgesia, severity and mortality.
Topics: Analgesics; Chi-Square Distribution; Clonidine; Critical Care; Cross-Sectional Studies; Delirium; Fe | 2020 |
Sedation practices during high dose rate brachytherapy for children with urogenital and perianal rhabdomyosarcoma.
Topics: Brachytherapy; Child; Child, Preschool; Delirium; Fentanyl; Humans; Hypnotics and Sedatives; Infant; | 2022 |
A National Multicenter Survey on Management of Pain, Agitation, and Delirium in Intensive Care Units in China.
Topics: Delirium; Dexmedetomidine; Fentanyl; Haloperidol; Humans; Hypnotics and Sedatives; Intensive Care Un | 2017 |
Risk Factors of Delirium in Sequential Sedation Patients in Intensive Care Units.
Topics: Adult; Aged; Anesthesia; Conscious Sedation; Critical Care; Delirium; Dexmedetomidine; Female; Fenta | 2017 |
Singapore SPICE: sedation practices in intensive care evaluation in Singapore - a prospective cohort study of the public healthcare system.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Intravenous; Cohort Studies; Critical Care; Delirium; F | 2020 |
Current practice and perceptions regarding pain, agitation and delirium management in patients receiving venovenous extracorporeal membrane oxygenation.
Topics: Adult; Analgesics, Opioid; Anesthesia; Anesthetics, Intravenous; Attitude of Health Personnel; Benzo | 2019 |
Patterns of opiate, benzodiazepine, and antipsychotic drug dosing in older patients in a medical intensive care unit.
Topics: Aged; Analgesics, Opioid; Antipsychotic Agents; Bayes Theorem; Benzodiazepines; Cohort Studies; Conn | 2013 |
Rapidly reversible, sedation-related delirium versus persistent delirium in the intensive care unit.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Conscious Sedation; Critical Care; Delirium; Female; Fen | 2014 |
Rapidly reversible, sedation-related delirium versus persistent delirium in the intensive care unit.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Conscious Sedation; Critical Care; Delirium; Female; Fen | 2014 |
Rapidly reversible, sedation-related delirium versus persistent delirium in the intensive care unit.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Conscious Sedation; Critical Care; Delirium; Female; Fen | 2014 |
Rapidly reversible, sedation-related delirium versus persistent delirium in the intensive care unit.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Conscious Sedation; Critical Care; Delirium; Female; Fen | 2014 |
Of delirium and sedation.
Topics: Conscious Sedation; Delirium; Female; Fentanyl; Humans; Hypnotics and Sedatives; Intensive Care Unit | 2014 |
Our enlightened understanding of the risks of persistent delirium.
Topics: Conscious Sedation; Delirium; Female; Fentanyl; Humans; Hypnotics and Sedatives; Intensive Care Unit | 2014 |
Only a small subset of sedation-related delirium is innocuous: we cannot let our guard down.
Topics: Conscious Sedation; Delirium; Female; Fentanyl; Humans; Hypnotics and Sedatives; Intensive Care Unit | 2014 |
Reply: Is the glass of delirium half full or half empty?
Topics: Conscious Sedation; Delirium; Female; Fentanyl; Humans; Hypnotics and Sedatives; Intensive Care Unit | 2014 |
Reply: The importance of determining the reason for intensive care unit delirium.
Topics: Conscious Sedation; Delirium; Female; Fentanyl; Humans; Hypnotics and Sedatives; Intensive Care Unit | 2014 |
A web-based survey of United Kingdom sedation practice in the intensive care unit.
Topics: Alfentanil; Analgesics, Opioid; Conscious Sedation; Critical Care; Data Collection; Deep Sedation; D | 2015 |
A retrospective comparison of dexmedetomidine versus midazolam for pediatric patients with congenital heart disease requiring postoperative sedation.
Topics: Anesthetics, Intravenous; Child, Preschool; Delirium; Dexmedetomidine; Dose-Response Relationship, D | 2015 |
Incidence of Delirium Among Patients Having Cancer Injected With Different Opioids for the First Time.
Topics: Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Cancer Pain; Delirium; Drug-Related Side Effects | 2017 |
Valproate for agitation in critically ill patients: A retrospective study.
Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Delirium; Dexmedetomidine; Female; Fentanyl; GABA | 2017 |
A case of infant delirium in the neonatal intensive care unit.
Topics: Amines; Analgesics, Opioid; Anti-Anxiety Agents; Cardiac Catheterization; Cyclohexanecarboxylic Acid | 2017 |
Clinical observations of postoperative delirium after surgery for oral carcinoma.
Topics: Age Factors; Analgesia, Patient-Controlled; Analgesics, Opioid; Carcinoma, Squamous Cell; Delirium; | 2009 |
[Incidence of intensive care unit delirium].
Topics: Adult; Aged; Analgesics, Opioid; Confusion; Critical Care; Delirium; Denmark; Fentanyl; Humans; Hypn | 2009 |
Dexmedetomidine in cardiac surgery patients who fail extubation and present with a delirium state.
Topics: Adrenergic alpha-2 Receptor Agonists; Anti-Anxiety Agents; Cardiac Surgical Procedures; Continuous P | 2011 |
Factors predisposing to coma and delirium: fentanyl and midazolam exposure; CYP3A5, ABCB1, and ABCG2 genetic polymorphisms; and inflammatory factors.
Topics: ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member | 2013 |
Agitated terminal delirium and association with partial opioid substitution and hydration.
Topics: Analgesics, Opioid; Delirium; Drug Administration Schedule; Female; Fentanyl; Humans; Japan; Male; M | 2003 |
Delirium as detected by the CAM-ICU predicts restraint use among mechanically ventilated medical patients.
Topics: Adult; Aged; Analgesics, Opioid; Delirium; Female; Fentanyl; Hospital Mortality; Humans; Hypnotics a | 2005 |
Delirium as detected by the CAM-ICU predicts restraint use among mechanically ventilated medical patients.
Topics: Adult; Aged; Analgesics, Opioid; Delirium; Female; Fentanyl; Hospital Mortality; Humans; Hypnotics a | 2005 |
Delirium as detected by the CAM-ICU predicts restraint use among mechanically ventilated medical patients.
Topics: Adult; Aged; Analgesics, Opioid; Delirium; Female; Fentanyl; Hospital Mortality; Humans; Hypnotics a | 2005 |
Delirium as detected by the CAM-ICU predicts restraint use among mechanically ventilated medical patients.
Topics: Adult; Aged; Analgesics, Opioid; Delirium; Female; Fentanyl; Hospital Mortality; Humans; Hypnotics a | 2005 |
A delirious patient with opioid intoxication after chewing a fentanyl patch.
Topics: Aged, 80 and over; Analgesics, Opioid; Delirium; Fentanyl; Humans; Male; Mastication; Risk Factors | 2006 |
[Physostigmine reversal of central anticholinergic syndrome induced by midazolam/fentanyl, benzoctamine/buprenorphine and etomidate/carticaine or by atropine/promethazine/pethidine for premedication? (author's transl)].
Topics: Adult; Aged; Anthracenes; Atropine; Benzodiazepines; Buprenorphine; Carticaine; Coma; Delirium; Etom | 1982 |
Fentanyl-associated delirium in man.
Topics: Adult; Delirium; Fentanyl; Humans; Male; Physostigmine | 1980 |
Acute toxic delirium: an uncommon reaction to transdermal fentanyl.
Topics: Acute Disease; Administration, Cutaneous; Adolescent; Analgesics, Opioid; Delirium; Fentanyl; Humans | 1995 |
After transdermal fentanyl: acute toxic delirium or central anticholinergic syndrome?
Topics: Acute Disease; Administration, Cutaneous; Adolescent; Analgesics, Opioid; Cholinergic Antagonists; C | 1996 |
Abuse of topical analgesic.
Topics: Administration, Topical; Alcoholism; Analgesics, Non-Narcotic; Delirium; Fentanyl; Humans; Infusions | 2001 |
Reversible delirium during opiod switching from transdermal fentanyl to methadone.
Topics: Administration, Cutaneous; Analgesics, Opioid; Delirium; Fentanyl; Humans; Male; Methadone; Middle A | 2001 |
Re: Reversible delirium during opioid switching.
Topics: Analgesics, Opioid; Delirium; Fentanyl; Humans; Methadone | 2001 |
Intensive care unit syndrome/delirium is associated with anemia, drug therapy and duration of ventilation treatment.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Analgesics, Opioid; Anemia; Delirium; Female; Fentanyl; | 2002 |
Acute toxic delirium in a patient using transdermal fentanyl.
Topics: Acute Disease; Aged; Delirium; Drug Delivery Systems; Female; Fentanyl; Humans | 1992 |
Acute postoperative delirium and extrapyramidal signs in a previously healthy parturient.
Topics: Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Cesarean Section; Delirium; Dyskinesia, Drug-I | 1988 |