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fentanyl and Decerebrate Posturing

fentanyl has been researched along with Decerebrate Posturing in 18 studies

Fentanyl: A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078)
fentanyl : A monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of N-phenyl-1-(2-phenylethyl)piperidin-4-amine with propanoic acid.

Research Excerpts

ExcerptRelevanceReference
" We report a case of a 19-month-old girl who presented in coma and who was later found to have a fentanyl patch adhered to her back."3.77Toxic leukoencephalopathy due to transdermal fentanyl overdose. ( Bradin, SA; Foy, L; Seeyave, DM, 2011)
" They also increased reactivity to CO(2) by lowering the phrenic nerve apnea threshold and shifting the phrenic nerve-CO(2) response curve to lower et(CO(2)) levels."3.72Dopamine1 receptor agonists reverse opioid respiratory network depression, increase CO2 reactivity. ( Lalley, PM, 2004)
" In this study, potential neuronal sites and mechanisms responsible for the disturbances were investigated, dose-response relationships were established, and it was determined whether general anesthesia plays a role."1.32Mu-opioid receptor agonist effects on medullary respiratory neurons in the cat: evidence for involvement in certain types of ventilatory disturbances. ( Lalley, PM, 2003)
" It appears that low intravenous doses of fentanyl act mainly in the spinal cord and that increasing the dosage recruits descending inhibition."1.30The involvement of bulbospinal pathways in fentanyl-induced inhibition of spinal withdrawal reflexes in the decerebrated rabbit. ( Clarke, RW; Houghton, AK; Ogilvie, J; Parry-Baggott, C, 1998)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19909 (50.00)18.7374
1990's3 (16.67)18.2507
2000's5 (27.78)29.6817
2010's1 (5.56)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Foy, L1
Seeyave, DM1
Bradin, SA1
Lalley, PM2
Lo, WC1
Jackson, E1
Merriman, A1
Harris, J2
Clarke, RW3
Janczewski, WA1
Feldman, JL1
Wu, KM1
Martin, WR1
Shingu, K1
Mori, K1
Komatsu, T1
Tomemori, N1
Osawa, M1
Parry-Baggott, C1
Houghton, AK1
Ogilvie, J1
Jenkins, S1
Witton, SK1
Schumacher, IG1
Arndt, JO1
Herrero, JF1
Headley, PM3
Noto, H1
Roppolo, JR1
de Groat, WC1
Nishizawa, O1
Sugaya, K1
Tsuchida, S1
Parsons, CG2
Tabatabai, M1
Kitahata, LM1
Collins, JG1
Maruyama, H1
Goto, K1
Sugai, N1
Rudatov, AG1
Sakai, Y1
Iwata, N1
Nishijima, Y1
Mori, M1

Reviews

1 review available for fentanyl and Decerebrate Posturing

ArticleYear
[Electrophysiological studies on the analgesic effects of general anesthetics (2)].
    Masui. The Japanese journal of anesthesiology, 1983, Volume: 32, Issue:2

    Topics: Analgesics; Anesthesia, General; Animals; Anterior Horn Cells; Cats; Decerebrate State; Fentanyl; Na

1983

Other Studies

17 other studies available for fentanyl and Decerebrate Posturing

ArticleYear
Toxic leukoencephalopathy due to transdermal fentanyl overdose.
    Pediatric emergency care, 2011, Volume: 27, Issue:9

    Topics: Accidents, Home; Administration, Cutaneous; Apnea; Child, Preschool; Coma; Decerebrate State; Delaye

2011
Mu-opioid receptor agonist effects on medullary respiratory neurons in the cat: evidence for involvement in certain types of ventilatory disturbances.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2003, Volume: 285, Issue:6

    Topics: Action Potentials; Analgesics, Opioid; Animals; Cats; Decerebrate State; Enkephalin, Ala(2)-MePhe(4)

2003
5-HT receptors involved in opioid-activated descending inhibition of spinal withdrawal reflexes in the decerebrated rabbit.
    Pain, 2004, Volume: 109, Issue:1-2

    Topics: Afferent Pathways; Analgesics, Opioid; Analysis of Variance; Animals; Blood Pressure; Decerebrate St

2004
Dopamine1 receptor agonists reverse opioid respiratory network depression, increase CO2 reactivity.
    Respiratory physiology & neurobiology, 2004, Feb-25, Volume: 139, Issue:3

    Topics: Action Potentials; Analgesics, Opioid; Analysis of Variance; Animals; Apnea; Carbon Dioxide; Cats; D

2004
Distinct rhythm generators for inspiration and expiration in the juvenile rat.
    The Journal of physiology, 2006, Jan-15, Volume: 570, Issue:Pt 2

    Topics: Aging; Animals; Biological Clocks; Decerebrate State; Exhalation; Female; Fentanyl; Inhalation; Lung

2006
An analysis of nicotinic and opioid processes in the medulla oblongata and nucleus ambiguus of the dog.
    The Journal of pharmacology and experimental therapeutics, 1983, Volume: 227, Issue:2

    Topics: Animals; Blood Pressure; Cyclazocine; Decerebrate State; Dogs; Electric Stimulation; Endorphins; Eth

1983
The involvement of bulbospinal pathways in fentanyl-induced inhibition of spinal withdrawal reflexes in the decerebrated rabbit.
    Pain, 1998, Volume: 78, Issue:3

    Topics: Adrenergic alpha-Antagonists; Analgesics, Opioid; Animals; Decerebrate State; Dose-Response Relation

1998
Cannabinoidergic and opioidergic inhibition of spinal reflexes in the decerebrated, spinalized rabbit.
    Neuropharmacology, 2001, Volume: 40, Issue:4

    Topics: Animals; Decerebrate State; Dose-Response Relationship, Drug; Dronabinol; Female; Fentanyl; Male; Na

2001
[The effect of methohexital, fentanyl, droperidol, and chloralose on the aortic baroceptor discharge of decerebrated cats (author's transl)].
    Der Anaesthesist, 1978, Volume: 27, Issue:1

    Topics: Animals; Aorta, Thoracic; Blood Pressure; Cats; Chloralose; Decerebrate State; Droperidol; Fentanyl;

1978
The effects of sham and full spinalization on the systemic potency of mu- and kappa-opioids on spinal nociceptive reflexes in rats.
    British journal of pharmacology, 1991, Volume: 104, Issue:1

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics

1991
Opioid modulation of the micturition reflex at the level of the pontine micturition center.
    Urologia internationalis, 1991, Volume: 47 Suppl 1

    Topics: Animals; Cats; Decerebrate State; Dogs; Endorphins; Fentanyl; Naloxone; Pons; Reflex; Urinary Bladde

1991
Spinal antinociceptive actions of mu- and kappa-opioids: the importance of stimulus intensity in determining 'selectivity' between reflexes to different modalities of noxious stimulus.
    British journal of pharmacology, 1989, Volume: 98, Issue:2

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics

1989
On the selectivity of intravenous mu- and kappa-opioids between nociceptive and non-nociceptive reflexes in the spinalized rat.
    British journal of pharmacology, 1989, Volume: 98, Issue:2

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Anesthetic

1989
Disruption of the rhythmic activity of the medullary inspiratory neurons and phrenic nerve by fentanyl and reversal with nalbuphine.
    Anesthesiology, 1989, Volume: 70, Issue:3

    Topics: Animals; Cats; Decerebrate State; Dose-Response Relationship, Drug; Female; Fentanyl; Male; Medulla

1989
[Effect of nitrous oxide alone or in combination with fentanyl on the spontaneous discharge of muscle nerves in the decerebrate cat].
    Masui. The Japanese journal of anesthesiology, 1986, Volume: 35, Issue:11

    Topics: Animals; Cats; Decerebrate State; Drug Interactions; Fentanyl; Neuromuscular Junction; Nitrous Oxide

1986
[Effect of substances used for neuroleptanalgesia on the synaptic transmission of stimulation in the spinal cord].
    Farmakologiia i toksikologiia, 1971, Volume: 34, Issue:1

    Topics: Animals; Benperidol; Cats; Decerebrate State; Depression, Chemical; Drug Synergism; Electric Stimula

1971
[Pharmacological studies on the effects of Thalamonal, a neuroleptanalgesic, on the motor system and the membrane].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1971, Volume: 46, Issue:5

    Topics: Action Potentials; Animals; Anura; Benperidol; Blood Pressure; Decerebrate State; Depression, Chemic

1971