fentanyl has been researched along with Craniocerebral Injuries in 21 studies
Fentanyl: A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078)
fentanyl : A monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of N-phenyl-1-(2-phenylethyl)piperidin-4-amine with propanoic acid.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We report a case of intraoperative fentanyl anaphylactic reaction." | 7.78 | [Fentanyl induced intraoperative anaphylactic reaction]. ( Makazu, H; Suzuki, T; Takahashi, H, 2012) |
| "We report a case of intraoperative fentanyl anaphylactic reaction." | 3.78 | [Fentanyl induced intraoperative anaphylactic reaction]. ( Makazu, H; Suzuki, T; Takahashi, H, 2012) |
| "The hemodynamic effects of a single dose of fentanyl (4 micrograms/kg) and of thiopental (5 mg/kg) were studied on cranial trauma patients who have hypertension and who are ventilated at constant volume and frequency." | 3.66 | [Single dose of thiopental or fentanyl. Hemodynamic effects after treatment by an anti-hypertensive drug: guanoxabenz (author's transl)]. ( Cavellat, M; Chapillon, M; Delhumeau, A; Leboulanger, J, 1981) |
| "Six patients with head trauma and ICP monitoring, sedated at the time of the study with propofol infusion and full neuromuscular blockade." | 2.69 | Sufentanil, fentanyl, and alfentanil in head trauma patients: a study on cerebral hemodynamics. ( Albanèse, J; Alliez, B; Martin, C; Potie, F; Rey, M; Viviand, X, 1999) |
| "The pharmacodynamic differences in time to onset and dissipation of effect of sufentanil, fentanyl, and alfentanil probably result from different rates of blood-brain equilibration." | 2.69 | Pharmacokinetics of human cerebral opioid extraction: a comparative study on sufentanil, fentanyl, and alfentanil in a patient after severe head injury. ( Göbel, L; Gruber, M; Hoerauf, KH; Metz, C; Taeger, K, 2000) |
| "Fentanyl was associated with an average ICP increase of 8 +/- 2 mmHg, and sufentanil with an increase of 6 +/- 1 mmHg." | 2.67 | Fentanyl and sufentanil increase intracranial pressure in head trauma patients. ( Bailey, PL; Pace, NL; Petersen, PB; Peterson, JC; Reichman, MV; Sperry, RJ, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (28.57) | 18.7374 |
| 1990's | 9 (42.86) | 18.2507 |
| 2000's | 5 (23.81) | 29.6817 |
| 2010's | 1 (4.76) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Makazu, H | 1 |
| Takahashi, H | 1 |
| Suzuki, T | 1 |
| Kondrat'ev, A | 1 |
| Paleĭ, DA | 1 |
| Kuzak, N | 1 |
| Harrison, DW | 1 |
| Zed, PJ | 1 |
| Delhumeau, A | 1 |
| Leboulanger, J | 1 |
| Chapillon, M | 1 |
| Cavellat, M | 1 |
| Hans, P | 1 |
| Martin, C | 2 |
| Bruder, N | 1 |
| Lassegue, D | 1 |
| Pelissier, D | 1 |
| Graziani, N | 1 |
| François, G | 1 |
| Tobias, JD | 1 |
| DeLima, LG | 1 |
| Kofke, WA | 1 |
| Tempelhoff, R | 1 |
| Weinstabl, C | 1 |
| Spiss, CK | 1 |
| Lauer, KK | 1 |
| Connolly, LA | 1 |
| Schmeling, WT | 1 |
| Albanèse, J | 1 |
| Viviand, X | 1 |
| Potie, F | 1 |
| Rey, M | 1 |
| Alliez, B | 1 |
| de Nadal, M | 1 |
| Munar, F | 1 |
| Poca, MA | 1 |
| Sahuquillo, J | 1 |
| Garnacho, A | 1 |
| Rosselló, J | 1 |
| Metz, C | 1 |
| Göbel, L | 1 |
| Gruber, M | 1 |
| Hoerauf, KH | 1 |
| Taeger, K | 1 |
| Lam, AM | 1 |
| Warner, DS | 1 |
| Sperry, RJ | 1 |
| Bailey, PL | 1 |
| Reichman, MV | 1 |
| Peterson, JC | 1 |
| Petersen, PB | 1 |
| Pace, NL | 1 |
| Jackson, FE | 1 |
| Fleming, PM | 1 |
| Wilcox, JR | 1 |
| Barbarick, DL | 1 |
| Cane, RD | 1 |
| Chrzanowski, R | 1 |
| Kamieniecka, B | 1 |
| Mańko, E | 1 |
| Moroz, J | 1 |
| Regieli, A | 1 |
| Szaroma, H | 1 |
| Brindle, GF | 1 |
| Fitch, W | 1 |
| Barker, J | 1 |
| Jennett, WB | 1 |
| McDowall, DG | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Early Lactate-Directed Therapy on the ICU: A Randomized Controlled Trial[NCT00270673] | Phase 3 | 350 participants (Anticipated) | Interventional | 2006-02-28 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 trials available for fentanyl and Craniocerebral Injuries
| Article | Year |
|---|---|
Opioid sedation does not alter intracranial pressure in head injured patients.
Topics: Adjuvants, Anesthesia; Adolescent; Adult; Analysis of Variance; Blood Pressure; Craniocerebral Traum | 1997 |
Sufentanil, fentanyl, and alfentanil in head trauma patients: a study on cerebral hemodynamics.
Topics: Adult; Alfentanil; Analgesics, Opioid; Analysis of Variance; Brain; Craniocerebral Trauma; Cross-Ove | 1999 |
Cerebral hemodynamic effects of morphine and fentanyl in patients with severe head injury: absence of correlation to cerebral autoregulation.
Topics: Adult; Analgesics, Opioid; Cerebrovascular Circulation; Craniocerebral Trauma; Female; Fentanyl; Hem | 2000 |
Pharmacokinetics of human cerebral opioid extraction: a comparative study on sufentanil, fentanyl, and alfentanil in a patient after severe head injury.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alfentanil; Analgesics, Opioid; Brain; Craniocerebral Tr | 2000 |
Fentanyl and sufentanil increase intracranial pressure in head trauma patients.
Topics: Adult; Craniocerebral Trauma; Double-Blind Method; Female; Fentanyl; Hemodynamics; Humans; Injection | 1992 |
Cerebral angiography: two anaesthetic techniques. A preliminary report.
Topics: Adolescent; Adult; Aged; Anesthesia, General; Brain Diseases; Brain Neoplasms; Carbon Dioxide; Cereb | 1973 |
15 other studies available for fentanyl and Craniocerebral Injuries
| Article | Year |
|---|---|
[Fentanyl induced intraoperative anaphylactic reaction].
Topics: Accidents, Traffic; Analgesics, Opioid; Anaphylaxis; Child; Craniocerebral Trauma; Fentanyl; Humans; | 2012 |
[Hemodynamic reaction attended safety in severe head injury patients at different periods of operative treatment].
Topics: Analgesics; Anesthetics, Combined; Anesthetics, Intravenous; Blood Circulation; Clonidine; Craniocer | 2005 |
Use of lidocaine and fentanyl premedication for neuroprotective rapid sequence intubation in the emergency department.
Topics: British Columbia; Cerebrovascular Disorders; Craniocerebral Trauma; Drug Utilization; Emergency Serv | 2006 |
[Single dose of thiopental or fentanyl. Hemodynamic effects after treatment by an anti-hypertensive drug: guanoxabenz (author's transl)].
Topics: Aged; Antihypertensive Agents; Craniocerebral Trauma; Drug Interactions; Fentanyl; Guanabenz; Guanid | 1981 |
[Sedation of patients with head injuries].
Topics: Craniocerebral Trauma; Critical Care; Fentanyl; Humans; Hypnotics and Sedatives | 1994 |
Energy expenditure and withdrawal of sedation in severe head-injured patients.
Topics: Acute Disease; Adult; Blood Pressure; Craniocerebral Trauma; Energy Metabolism; Fentanyl; Glasgow Co | 1994 |
Increased intracranial pressure after fentanyl administration in a child with closed head trauma.
Topics: Animals; Child; Craniocerebral Trauma; Fentanyl; Humans; Intracranial Pressure; Male; Pain; Wounds, | 1994 |
Cerebrovascular autoregulation may be the probable mechanism responsible for fentanyl- and sufentanil-induced increases in intracranial pressure in patients with head trauma.
Topics: Brain; Cerebrovascular Circulation; Craniocerebral Trauma; Fentanyl; Humans; Intracranial Pressure; | 1993 |
Increased intracranial pressure in head trauma patients given fentanyl or sufentanil.
Topics: Blood Pressure; Blood Volume; Brain; Craniocerebral Trauma; Fentanyl; Humans; Intracranial Pressure; | 1993 |
Fentanyl and sufentanil increase intracranial pressure in head trauma patients.
Topics: Craniocerebral Trauma; Fentanyl; Humans; Intracranial Pressure; Midazolam; Morphine; Pseudotumor Cer | 1993 |
Opiates, intracranial pressure, and autoregulation.
Topics: Craniocerebral Trauma; Fentanyl; Hemodynamics; Homeostasis; Humans; Intracranial Pressure; Morphine; | 2001 |
Neuroleptanalgesia for carotid angiography in neurosurgical patients.
Topics: Adult; Benperidol; Cerebral Angiography; Craniocerebral Trauma; Fentanyl; Humans; Male; Meningioma; | 1973 |
Neuroleptanalgesia in cerebral angiography.
Topics: Anesthetics; Benperidol; Bradycardia; Brain Injuries; Butyrophenones; Carotid Artery, Internal; Cere | 1973 |
The use of neuroleptic agents in a neurosurgical unit.
Topics: Benperidol; Cerebral Angiography; Chlorpromazine; Craniocerebral Trauma; Electrodes; Epilepsy; Fenta | 1969 |
The influence of neuroleptanalgesic drugs on cerebrospinal fluid pressure.
Topics: Adolescent; Adult; Analgesics; Arteries; Benperidol; Blood Pressure; Carbon Dioxide; Central Venous | 1969 |