Page last updated: 2024-10-27

fentanyl and Consciousness, Loss of

fentanyl has been researched along with Consciousness, Loss of in 18 studies

Fentanyl: A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078)
fentanyl : A monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of N-phenyl-1-(2-phenylethyl)piperidin-4-amine with propanoic acid.

Research Excerpts

ExcerptRelevanceReference
" Clinical features included typical opioid symptoms such as unconsciousness, respiratory depression, and apnea."3.81Opioid intoxications involving butyrfentanyl, 4-fluorobutyrfentanyl, and fentanyl from the Swedish STRIDA project. ( Bäckberg, M; Beck, O; Helander, A; Jönsson, KH, 2015)
"The mean BIS value at loss of consciousness was significantly different between the two groups (74."2.71Performance of bispectral index and auditory evoked potential monitors in detecting loss of consciousness during anaesthetic induction with propofol with and without fentanyl. ( Kudo, M; Kudo, T; Matsuki, A; Mi, WD; Sakai, T, 2004)
"Propofol and fentanyl were administered via computer-assisted continuous infusion to provide pseudo-steady-state concentrations and allow equilibration between plasma-blood concentration and their biophase concentration."2.67The interaction of fentanyl on the Cp50 of propofol for loss of consciousness and skin incision. ( Canada, AT; Glass, PS; Goodman, D; Jhaveri, R; McEwan, AI; Smith, C; Smith, LR; Wilkinson, M, 1994)
"Fentanyl was infused at a rate of 150 micrograms/min until a total of 15 micrograms/kg had been administered."1.29Fentanyl-induced rigidity and unconsciousness in human volunteers. Incidence, duration, and plasma concentrations. ( Ashburn, MA; Bailey, PL; LeMaire, L; Stanley, TH; Streisand, JB; Tarver, SD; Varvel, J, 1993)
"The effect of midazolam on the induction dose-response curve for alfentanil was studied in nonpremedicated ASA physical status I or II patients."1.28Midazolam-alfentanil synergism for anesthetic induction in patients. ( Bradley, EL; Kissin, I; Vinik, HR, 1989)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19904 (22.22)18.7374
1990's4 (22.22)18.2507
2000's6 (33.33)29.6817
2010's4 (22.22)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Yang, W1
Geng, Y1
Liu, Y1
Li, A1
Liu, J1
Xing, J1
Li, W1
Melcer, T2
Walker, J2
Sechriest, VF1
Lebedda, M2
Quinn, K2
Galarneau, M2
Bhatnagar, V1
Richard, E1
Han, P1
Sechriest, V1
Bäckberg, M1
Beck, O1
Jönsson, KH1
Helander, A1
Reeves, MD1
Ginifer, CJ1
Bauman, LA1
Cannon, ML1
McCloskey, J1
Allen, S1
James, RL1
Tobin, JR1
Politis, GD1
Regnard, C1
Pelham, A1
Gil-Gouveia, R1
Wilkinson, PA1
Kaube, H1
Mi, WD1
Sakai, T1
Kudo, T1
Kudo, M1
Matsuki, A1
Yanagawa, Y1
Sakamoto, T1
Okada, Y1
Tuzuki, N1
Katoh, H1
Hiroshi, N1
Shima, K1
Sebel, PS1
Bovill, JG1
Wauquier, A1
Rog, P1
Smith, C1
McEwan, AI1
Jhaveri, R1
Wilkinson, M1
Goodman, D1
Smith, LR1
Canada, AT1
Glass, PS1
Streisand, JB1
Bailey, PL1
LeMaire, L1
Ashburn, MA1
Tarver, SD1
Varvel, J1
Stanley, TH2
Sieber, FE1
Brown, PR1
Wu, Y1
Koehler, RC1
Traystman, RJ1
Haberham, ZL1
van den Brom, WE1
Venker-van Haagen, AJ1
Baumans, V1
de Groot, HN1
Hellebrekers, LJ1
Schaer, H1
Baasch, K1
Reist, F1
Vinik, HR1
Bradley, EL1
Kissin, I1
de Lange, S1

Reviews

1 review available for fentanyl and Consciousness, Loss of

ArticleYear
Severe hemiplegic migraine attack precipitated by fentanyl sedation for esophagogastroscopy.
    Neurology, 2004, Dec-28, Volume: 63, Issue:12

    Topics: Analgesics, Opioid; Esophagoscopy; Female; Fentanyl; Gastroscopy; Hemiplegia; Humans; Hypnotics and

2004

Trials

5 trials available for fentanyl and Consciousness, Loss of

ArticleYear
Comparison of effects of thoracic epidural and intravenous administration of lidocaine on target-controlled infusion of propofol and tracheal intubation response during induction of anesthesia.
    Journal of cardiothoracic and vascular anesthesia, 2013, Volume: 27, Issue:6

    Topics: Adult; Anesthesia, Epidural; Anesthesia, Intravenous; Anesthetics, Intravenous; Anesthetics, Local;

2013
Unconscious sedation in children: a prospective multi-arm clinical trial.
    Paediatric anaesthesia, 2002, Volume: 12, Issue:8

    Topics: Anesthesia Recovery Period; Anesthetics, Combined; Anesthetics, Intravenous; Child; Child, Preschool

2002
Performance of bispectral index and auditory evoked potential monitors in detecting loss of consciousness during anaesthetic induction with propofol with and without fentanyl.
    European journal of anaesthesiology, 2004, Volume: 21, Issue:10

    Topics: Adolescent; Adult; Analgesics, Opioid; Anesthesia, General; Anesthetics, Combined; Anesthetics, Intr

2004
The interaction of fentanyl on the Cp50 of propofol for loss of consciousness and skin incision.
    Anesthesiology, 1994, Volume: 81, Issue:4

    Topics: Adult; Anesthesia, Intravenous; Consciousness; Dose-Response Relationship, Drug; Drug Interactions;

1994
[Respiratory depression after fentanyl and antagonism by naloxone (author's transl)].
    Der Anaesthesist, 1978, Volume: 27, Issue:6

    Topics: Adolescent; Adult; Aged; Anesthesia, General; Fentanyl; Flunitrazepam; Humans; Meperidine; Middle Ag

1978

Other Studies

12 other studies available for fentanyl and Consciousness, Loss of

ArticleYear
Glasgow Coma Scores, early opioids, and posttraumatic stress disorder among combat amputees.
    Journal of traumatic stress, 2014, Volume: 27, Issue:2

    Topics: Afghan Campaign 2001-; Amnesia; Amputees; Analgesics, Opioid; Comorbidity; Drug Therapy, Combination

2014
Glasgow Coma Scale scores, early opioids, and 4-year psychological outcomes among combat amputees.
    Journal of rehabilitation research and development, 2014, Volume: 51, Issue:5

    Topics: Adult; Afghan Campaign 2001-; Amputation, Surgical; Amputation, Traumatic; Amputees; Analgesics, Opi

2014
Opioid intoxications involving butyrfentanyl, 4-fluorobutyrfentanyl, and fentanyl from the Swedish STRIDA project.
    Clinical toxicology (Philadelphia, Pa.), 2015, Volume: 53, Issue:7

    Topics: Adult; Analgesics, Opioid; Apnea; Chromatography, Liquid; Dose-Response Relationship, Drug; Emergenc

2015
Fatal intravenous misuse of transdermal fentanyl.
    The Medical journal of Australia, 2002, Nov-18, Volume: 177, Issue:10

    Topics: Administration, Cutaneous; Adult; Analgesics, Opioid; Blood Gas Analysis; Drug Overdose; Emergency T

2002
Severe respiratory depression and sedation with transdermal fentanyl: four case studies.
    Palliative medicine, 2003, Volume: 17, Issue:8

    Topics: Administration, Cutaneous; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Fatal Outcome; Female

2003
Intubation without premedication may worsen outcome for unconsciousness patients with intracranial hemorrhage.
    The American journal of emergency medicine, 2005, Volume: 23, Issue:2

    Topics: Analgesics, Opioid; Anesthetics, Local; Anti-Anxiety Agents; Diazepam; Emergency Medicine; Female; F

2005
Effects of high-dose fentanyl anesthesia on the electroencephalogram.
    Anesthesiology, 1981, Volume: 55, Issue:3

    Topics: Amnesia; Analgesia; Anesthesia, General; Cardiac Surgical Procedures; Electroencephalography; Fentan

1981
Fentanyl-induced rigidity and unconsciousness in human volunteers. Incidence, duration, and plasma concentrations.
    Anesthesiology, 1993, Volume: 78, Issue:4

    Topics: Adult; Fentanyl; Heart Rate; Humans; Male; Muscle Rigidity; Unconsciousness

1993
Cerebral blood flow responsivity to CO2 in anesthetized chronically diabetic dogs.
    The American journal of physiology, 1993, Volume: 264, Issue:4 Pt 2

    Topics: Animals; Blood Glucose; Carbon Dioxide; Cerebrovascular Circulation; Diabetes Mellitus, Experimental

1993
EEG evaluation of reflex testing as assessment of depth of pentobarbital anaesthesia in the rat.
    Laboratory animals, 1999, Volume: 33, Issue:1

    Topics: Analgesics, Opioid; Anesthesia; Anesthetics, Intravenous; Animals; Buprenorphine; Butyrophenones; El

1999
Midazolam-alfentanil synergism for anesthetic induction in patients.
    Anesthesia and analgesia, 1989, Volume: 69, Issue:2

    Topics: Adolescent; Adult; Alfentanil; Anesthesia, Intravenous; Anesthetics; Dose-Response Relationship, Dru

1989
Comparison of sufentanil-oxygen and fentanyl-oxygen anesthesia for mitral and aortic valvular surgery.
    Journal of cardiothoracic anesthesia, 1988, Volume: 2, Issue:1

    Topics: Anesthesia, Intravenous; Anesthetics; Aortic Valve; Blood Pressure; Cardiopulmonary Bypass; Fentanyl

1988