Page last updated: 2024-10-27

fentanyl and Complex Regional Pain Syndromes

fentanyl has been researched along with Complex Regional Pain Syndromes in 6 studies

Fentanyl: A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078)
fentanyl : A monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of N-phenyl-1-(2-phenylethyl)piperidin-4-amine with propanoic acid.

Complex Regional Pain Syndromes: Conditions characterized by pain involving an extremity or other body region, HYPERESTHESIA, and localized autonomic dysfunction following injury to soft tissue or nerve. The pain is usually associated with ERYTHEMA; SKIN TEMPERATURE changes, abnormal sudomotor activity (i.e., changes in sweating due to altered sympathetic innervation) or edema. The degree of pain and other manifestations is out of proportion to that expected from the inciting event. Two subtypes of this condition have been described: type I; (REFLEX SYMPATHETIC DYSTROPHY) and type II; (CAUSALGIA). (From Pain 1995 Oct;63(1):127-33)

Research Excerpts

ExcerptRelevanceReference
"Complex regional pain syndrome is a chronic pain condition characterized by autonomic dysfunction, changes in sympathetic and vasomotor activity, and sensory and motor changes."1.72Atypical dermatologic manifestations in complex regional pain syndrome: a case report. ( Abcejo, AS; Langford, B; Pittelkow, TP, 2022)
"A 26-year-old man presented with severe complex regional pain syndrome type I of the affected limb after a work-related electrical injury."1.31Complex regional pain syndrome (type I) after electrical injury: a case report of treatment with continuous epidural block. ( Bryant, P; Kim, CT, 2001)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (16.67)29.6817
2010's4 (66.67)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Langford, B1
Pittelkow, TP1
Abcejo, AS1
Cohen, SP2
Hameed, H2
Kurihara, C1
Pasquina, PF2
Patel, AM1
Babade, M1
Griffith, SR1
Erdek, ME1
Jamison, DE1
Hurley, RW2
Wasan, AD1
Manchikanti, L1
Benyamin, RM1
Candido, KD1
Hirsch, JA1
Kim, CT1
Bryant, P1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Randomized, Cross-over Study Evaluating the Effect of Sedation on Pain Relief After Diagnostic Injections[NCT01472835]73 participants (Actual)Interventional2011-03-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Oswestry Disability Index

Measure of functional capacity on a scale ranging from 0% to 100%, with 0% signifying no disability (NCT01472835)
Timeframe: 1-month

Interventionunits on a scale (Mean)
Sedation34.8
Control40.6

Pain Score

0-10 numerical rating scale (NRS) pain scale. 0 being no pain and 10 being the worst possible pain. (NCT01472835)
Timeframe: 1-month

Interventionunits on a scale (Mean)
Sedation5.1
Control5.6

Pain Score

pain diary using 0-10 scale, with 0 being no pain and 10 being the worst pain imaginable (NCT01472835)
Timeframe: through 6 hours after injection

Interventionunits on a scale (Mean)
Sedation2.2
Control3.4

Procedure-related Pain Score

0-10 pain scale, with 0 being no pain and 10 being the worst pain imaginable (NCT01472835)
Timeframe: 1 day

Interventionunits on a scale (Mean)
Sedation3.1
Control5.5

Satisfaction

5-point Likert scale. The scale is from 1-5. 1 being very unsatisfied and 5 being very satisfied. (NCT01472835)
Timeframe: 1 day

Interventionunits on a scale (Mean)
Sedation4.0
Control3.6

Trials

1 trial available for fentanyl and Complex Regional Pain Syndromes

ArticleYear
The effect of sedation on the accuracy and treatment outcomes for diagnostic injections: a randomized, controlled, crossover study.
    Pain medicine (Malden, Mass.), 2014, Volume: 15, Issue:4

    Topics: Adult; Aged; Anesthetics, Intravenous; Autonomic Nerve Block; Complex Regional Pain Syndromes; Consc

2014

Other Studies

5 other studies available for fentanyl and Complex Regional Pain Syndromes

ArticleYear
Atypical dermatologic manifestations in complex regional pain syndrome: a case report.
    Journal of medical case reports, 2022, Jun-27, Volume: 16, Issue:1

    Topics: Adult; Complex Regional Pain Syndromes; Extremities; Fentanyl; Humans; Male; Pain; Pain Measurement

2022
Efficacy vs effectiveness and explanatory vs pragmatic: where is the balance point in pain medicine research?
    Pain medicine (Malden, Mass.), 2014, Volume: 15, Issue:4

    Topics: Anesthetics, Intravenous; Autonomic Nerve Block; Complex Regional Pain Syndromes; Conscious Sedation

2014
Sedation for diagnostic injections: prioritizing patient interests.
    Pain medicine (Malden, Mass.), 2014, Volume: 15, Issue:11

    Topics: Anesthetics, Intravenous; Autonomic Nerve Block; Complex Regional Pain Syndromes; Conscious Sedation

2014
Cohen et al. Reach inappropriate conclusions on the effect of sedation on the accuracy and treatment outcomes for diagnostic injections.
    Pain medicine (Malden, Mass.), 2014, Volume: 15, Issue:11

    Topics: Anesthetics, Intravenous; Autonomic Nerve Block; Complex Regional Pain Syndromes; Conscious Sedation

2014
Complex regional pain syndrome (type I) after electrical injury: a case report of treatment with continuous epidural block.
    Archives of physical medicine and rehabilitation, 2001, Volume: 82, Issue:7

    Topics: Adult; Analgesics, Opioid; Anesthetics, Local; Arm Injuries; Burns, Electric; Complex Regional Pain

2001