Page last updated: 2024-10-27

fentanyl and Cocaine Abuse

fentanyl has been researched along with Cocaine Abuse in 14 studies

Fentanyl: A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078)
fentanyl : A monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of N-phenyl-1-(2-phenylethyl)piperidin-4-amine with propanoic acid.

Research Excerpts

ExcerptRelevanceReference
" Recently, drug overdoses caused by fentanyl-laced cocaine specifically are on the rise."3.91Computational Systems Pharmacology-Target Mapping for Fentanyl-Laced Cocaine Overdose. ( Chen, M; Cheng, J; Feng, Z; Lin, W; Wang, S; Wang, Y; Wu, N; Xie, XQ, 2019)
" Twenty-five individuals seeking outpatient treatment for cocaine abuse or dependence (DSM-IV) received up to 12 weeks of cognitive-behavioral therapy and cocaine abstinence reinforcement, whereby each cocaine-free urine was reinforced with vouchers redeemable for goods."3.76Brain mu-opioid receptor binding predicts treatment outcome in cocaine-abusing outpatients. ( Bencherif, B; Boyd, SJ; Copersino, ML; Endres, CJ; Epstein, DH; Frost, JJ; Ghitza, UE; Gorelick, DA; Kuwabara, H; Preston, KL, 2010)
"Synephrine was found in biological samples of these patients in high concentrations and was suspected to be an adulterant in illicitly obtained drugs."1.91Profound Hyperthermia Associated With Fentanyl and Cocaine Use With Suspected Synephrine Adulteration. ( Choe, AJ; Ellison, R; Gerona, R; Nacca, N; Ramaswamy, SR; Schult, RF, 2023)
"Carfentanil was detected along with other drugs in all cases with no alcohol detected in the post-mortem blood in any of the cases."1.48A Series of Deaths Involving Carfentanil in the UK and Associated Post-mortem Blood Concentrations. ( Elliott, SP; Hernandez Lopez, E, 2018)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (7.14)18.2507
2000's4 (28.57)29.6817
2010's7 (50.00)24.3611
2020's2 (14.29)2.80

Authors

AuthorsStudies
Choe, AJ1
Ellison, R1
Ramaswamy, SR1
Schult, RF1
Gerona, R1
Nacca, N1
Ciccarone, D1
Elliott, SP1
Hernandez Lopez, E1
Duru, UB1
Pawar, G1
Barash, JA1
Miller, LE1
Thiruselvam, IK1
Haut, MW1
Angela Parham, M1
Pomerleau, AC1
Peralta, G1
Drenzek, CL1
Edison, LS1
Khatri, UG1
Viner, K1
Perrone, J1
Cheng, J1
Wang, S1
Lin, W1
Wu, N1
Wang, Y1
Chen, M1
Xie, XQ1
Feng, Z1
Gorelick, DA4
Kim, YK2
Bencherif, B3
Boyd, SJ3
Nelson, R2
Copersino, ML2
Dannals, RF2
Frost, JJ4
Sharma, RK1
Ghitza, UE1
Preston, KL1
Epstein, DH1
Kuwabara, H1
Endres, CJ2
Minkowski, CP1
Epstein, D1
Copersino, M1
Kramer, C1
Tawney, M1
Morgan, AD1
Campbell, UC1
Fons, RD1
Carroll, ME1

Reviews

1 review available for fentanyl and Cocaine Abuse

ArticleYear
The rise of illicit fentanyls, stimulants and the fourth wave of the opioid overdose crisis.
    Current opinion in psychiatry, 2021, 07-01, Volume: 34, Issue:4

    Topics: Analgesics, Opioid; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Comorbidi

2021

Other Studies

13 other studies available for fentanyl and Cocaine Abuse

ArticleYear
Profound Hyperthermia Associated With Fentanyl and Cocaine Use With Suspected Synephrine Adulteration.
    The Journal of emergency medicine, 2023, Volume: 64, Issue:2

    Topics: Cocaine; Cocaine-Related Disorders; Female; Fentanyl; Humans; Hyperthermia, Induced; Male; Synephrin

2023
A Series of Deaths Involving Carfentanil in the UK and Associated Post-mortem Blood Concentrations.
    Journal of analytical toxicology, 2018, May-01, Volume: 42, Issue:4

    Topics: Adult; Analgesics, Opioid; Cocaine-Related Disorders; Female; Fentanyl; Forensic Toxicology; Heroin

2018
An Unusual Amnestic Syndrome Associated With Combined Fentanyl and Cocaine Use.
    Annals of internal medicine, 2018, 05-15, Volume: 168, Issue:10

    Topics: Adult; Amnesia; Cocaine-Related Disorders; Fentanyl; Globus Pallidus; Hippocampus; Humans; Male; Opi

2018
Fentanyl-associated illness among substance users - Fulton County, Georgia, 2015.
    The American journal of emergency medicine, 2018, Volume: 36, Issue:11

    Topics: Adolescent; Adult; Aged; Amphetamine-Related Disorders; Analgesics, Opioid; Case-Control Studies; Co

2018
Lethal Fentanyl and Cocaine Intoxication.
    The New England journal of medicine, 2018, 11-01, Volume: 379, Issue:18

    Topics: Cocaine; Cocaine-Related Disorders; Drug Overdose; Female; Fentanyl; Humans; Male; Middle Aged; Penn

2018
Computational Systems Pharmacology-Target Mapping for Fentanyl-Laced Cocaine Overdose.
    ACS chemical neuroscience, 2019, 08-21, Volume: 10, Issue:8

    Topics: Analgesics, Opioid; Cocaine; Cocaine-Related Disorders; Computer Simulation; Drug Overdose; Fentanyl

2019
Brain mu-opioid receptor binding: relationship to relapse to cocaine use after monitored abstinence.
    Psychopharmacology, 2008, Volume: 200, Issue:4

    Topics: Adult; Behavior, Addictive; Brain; Cocaine-Related Disorders; Female; Fentanyl; Follow-Up Studies; F

2008
Retrospective diagnosis of cocaine addiction: role of preoperative electrocardiogram.
    Anaesthesia and intensive care, 2008, Volume: 36, Issue:5

    Topics: Androstanols; Anesthetics, Intravenous; Cocaine-Related Disorders; Contracture; Electrocardiography;

2008
Brain mu-opioid receptor binding predicts treatment outcome in cocaine-abusing outpatients.
    Biological psychiatry, 2010, Oct-15, Volume: 68, Issue:8

    Topics: Adult; Brain; Cocaine; Cocaine-Related Disorders; Cognitive Behavioral Therapy; Female; Fentanyl; Hu

2010
Differential response to IV carfentanil in chronic cocaine users and healthy controls.
    Addiction biology, 2012, Volume: 17, Issue:1

    Topics: Adult; Analgesics, Opioid; Brain; Cocaine-Related Disorders; Dizziness; Female; Fentanyl; Half-Life;

2012
Imaging brain mu-opioid receptors in abstinent cocaine users: time course and relation to cocaine craving.
    Biological psychiatry, 2005, Jun-15, Volume: 57, Issue:12

    Topics: Adult; Analgesics, Opioid; Brain; Brain Mapping; Carbon Isotopes; Cocaine-Related Disorders; Female;

2005
A fatal overdose of transdermally administered fentanyl.
    The Journal of the American Osteopathic Association, 1998, Volume: 98, Issue:7

    Topics: Administration, Cutaneous; Adult; Analgesics, Opioid; Cocaine-Related Disorders; Drug Overdose; Fata

1998
Effects of agmatine on the escalation of intravenous cocaine and fentanyl self-administration in rats.
    Pharmacology, biochemistry, and behavior, 2002, Volume: 72, Issue:4

    Topics: Agmatine; Analgesics, Opioid; Animals; Body Weight; Cocaine-Related Disorders; Conditioning, Operant

2002