Page last updated: 2024-10-27

fentanyl and Chronic Kidney Failure

fentanyl has been researched along with Chronic Kidney Failure in 25 studies

Fentanyl: A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078)
fentanyl : A monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of N-phenyl-1-(2-phenylethyl)piperidin-4-amine with propanoic acid.

Research Excerpts

ExcerptRelevanceReference
"This review evaluates current recommendations for pain management in chronic kidney disease (CKD) and end-stage kidney disease (ESKD) with a specific focus on evidence for opioid analgesia, including the partial agonist, buprenorphine."3.96Pain management in patients with chronic kidney disease and end-stage kidney disease. ( Dember, LM; Jhamb, M; Liebschutz, J; Roy, PJ; Weltman, M, 2020)
"We aim to describe management of a patient receiving renal transplantation for chronic renal failure due to Alport syndrome with low dose of intrathecal bupivacaine and continuous epidural infusion of local anesthetic."3.83Low-dose Spinal Block With Continuous Epidural Infusion for Renal Transplantation in a Patient With Alport Syndrome: A Case Report. ( Brazzi, L; Bretto, P; Donadio, PP; Gobbi, F; Sales, G, 2016)
" Anesthesia was maintained with fentanyl and midazolam."3.69[The anesthetic management of patients in chronic renal failure for coronary artery bypass surgery without cardiopulmonary bypass]. ( Gotou, K; Hashimoto, Y; Kimura, F; Kimura, N; Wakayama, S, 1997)
"He had chronic renal failure and on hemodialysis (HD) for 22 years."1.31[General anesthesia for a patient on hemodialysis with arteriosclerosis obliterans]. ( Hanaoka, K; Nishiyama, T; Otsuji, M; Yajima, C, 2000)
" Though both volume of distribution and elimination half-life increased in the posttransplantation period, only the decrease in clearance was statistically significant."1.28Effects of cholestatic hepatic disease and chronic renal failure on alfentanil pharmacokinetics in children. ( Brandom, BW; Cook, DR; Davis, JE; Davis, PJ; Scierka, AM; Stiller, RL, 1989)
" In a case of end stage renal failure, the pharmacokinetic parameters during cardiac surgery were similar to 18 children from the same age group with normal renal function."1.27Pharmacokinetics of fentanyl in children with renal disease. ( Crean, P; Goresky, GV; Klein, J; Koren, G; MacLeod, SM, 1984)
" The effects of chronic renal failure (CRF) on the pharmacokinetic profile of sufentanil were evaluated in six adolescent patients undergoing renal transplantation, and these findings were compared with data from age-matched control patients with normal renal function who were undergoing other surgical procedures."1.27Pharmacokinetics of sufentanil in adolescent patients with chronic renal failure. ( Brandom, BW; Cook, DR; Davin-Robinson, KA; Davis, PJ; Stiller, RL, 1988)
" These changes, in turn, may result in pharmacokinetic alterations in affected patients."1.27Pharmacokinetics of sufentanil in patients undergoing renal transplantation. ( Avitable, M; Butt, K; Casthely, PA; Fyman, PN; Moser, F; Reynolds, JR, 1988)
" Elimination half-life and plasma clearance were similar in both groups."1.27Pharmacokinetics of alfentanil in chronic renal failure. ( Chauvin, M; Duvaldestin, P; Lebrault, C; Levron, JC, 1987)
"In patients with chronic renal failure, a correlation of probability P less than 0."1.26Plasma protein binding of fentanyl: the effect of hyperlipoproteinaemia and chronic renal failure. ( Bower, S, 1982)

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-199012 (48.00)18.7374
1990's5 (20.00)18.2507
2000's3 (12.00)29.6817
2010's4 (16.00)24.3611
2020's1 (4.00)2.80

Authors

AuthorsStudies
Roy, PJ1
Weltman, M1
Dember, LM1
Liebschutz, J1
Jhamb, M1
Jun, JH1
Kim, GS1
Lee, JJ1
Ko, JS1
Kim, SJ1
Jeon, PH1
Sen, I1
Thomas, S1
Arya, VK1
Minz, M1
Han, J1
Saraf, SL1
Gordeuk, VR1
Gowhari, M1
Gobbi, F1
Sales, G1
Bretto, P1
Donadio, PP1
Brazzi, L1
Honda, A1
Arai, T1
Akiyama, M1
Masuda, E1
Kobayashi, M1
Hoka, S1
Dhir, S1
Fuller, J1
Koren, G1
Crean, P1
Goresky, GV1
Klein, J1
MacLeod, SM1
Bower, S1
Gramatikova, R1
Ianev, Ia1
Panchev, P1
Vitanova, S1
Takita, K1
Goda, Y1
Kemmotsu, O1
Mashio, H1
Okuyama, A1
Ito, Y1
Sakamoto, H1
Kawahigashi, H1
Kingsley, CP1
Chronister, T1
Cohen, DJ1
Parrish, JM1
Drew, R1
Bongiovanni, MB1
Mercadante, S1
Caligara, M1
Sapio, M1
Serretta, R1
Lodi, F1
Gotou, K1
Kimura, F1
Kimura, N1
Hashimoto, Y1
Wakayama, S1
Kurokawa, S1
Taga, K1
Tobita, T1
Kitahara, Y1
Fukuda, S1
Shimoji, K1
Otsuji, M1
Nishiyama, T1
Yajima, C1
Hanaoka, K1
Davis, PJ2
Stiller, RL2
Cook, DR2
Brandom, BW2
Davis, JE1
Scierka, AM1
Wiggum, DC1
Cork, RC1
Weldon, ST1
Gandolfi, AJ1
Perry, DS1
Davin-Robinson, KA1
Fyman, PN1
Reynolds, JR1
Moser, F1
Avitable, M1
Casthely, PA1
Butt, K1
Van Peer, A1
Vercauteren, M1
Noorduin, H1
Woestenborghs, R1
Heykants, J1
Chauvin, M1
Lebrault, C1
Levron, JC1
Duvaldestin, P1
Mostert, JW2
Evers, JL2
Hobika, GH2
Moore, RH2
Ambrus, JL1
Murphy, GP1
Kacki, J1
Mayzner, E1
Zawadzki, A1
Siedlecki, J1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Quadratus Lumborum Block for Analgesia After Living Donor Kidney Transplantation: A Randomized Controlled Trial[NCT04908761]88 participants (Actual)Interventional2021-06-03Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for fentanyl and Chronic Kidney Failure

ArticleYear
Preinduction hemodynamic fluctuations in renal transplant recipients--comparison of two combined anesthesia regimens.
    Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia, 2014, Volume: 25, Issue:6

    Topics: Adolescent; Adult; Allografts; Anesthesia, Epidural; Anesthesia, General; Anesthetics, Local; Bupiva

2014

Other Studies

24 other studies available for fentanyl and Chronic Kidney Failure

ArticleYear
Pain management in patients with chronic kidney disease and end-stage kidney disease.
    Current opinion in nephrology and hypertension, 2020, Volume: 29, Issue:6

    Topics: Analgesics, Opioid; Buprenorphine; Fentanyl; Humans; Hydromorphone; Kidney Failure, Chronic; Oxycodo

2020
Comparison of intrathecal morphine and surgical-site infusion of ropivacaine as adjuncts to intravenous patient-controlled analgesia in living-donor kidney transplant recipients.
    Singapore medical journal, 2017, Volume: 58, Issue:11

    Topics: Adult; Aged; Amides; Analgesia, Patient-Controlled; Analgesics, Opioid; Female; Fentanyl; Humans; In

2017
Safety of chronic transdermal fentanyl use in patients receiving hemodialysis.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2016, Jul-01, Volume: 73, Issue:13

    Topics: Administration, Cutaneous; Adult; Analgesics, Opioid; Female; Fentanyl; Humans; Kidney Failure, Chro

2016
Low-dose Spinal Block With Continuous Epidural Infusion for Renal Transplantation in a Patient With Alport Syndrome: A Case Report.
    Transplantation proceedings, 2016, Volume: 48, Issue:9

    Topics: Adult; Analgesia, Epidural; Anesthesia, Epidural; Anesthesia, General; Anesthesia, Spinal; Anestheti

2016
Anesthetic management of a patient with a history of Batista procedure for dilated cardiomyopathy undergoing gastric surgery.
    Journal of anesthesia, 2006, Volume: 20, Issue:3

    Topics: Anesthesia, Epidural; Anesthesia, General; Anesthetics, Intravenous; Anesthetics, Local; Bupivacaine

2006
Case report: pregnancy in hemodialysis-dependent end-stage renal disease: anesthetic considerations.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2007, Volume: 54, Issue:7

    Topics: Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Anesthetics, Intravenous; Anesthetics, Local;

2007
Pharmacokinetics of fentanyl in children with renal disease.
    Research communications in chemical pathology and pharmacology, 1984, Volume: 46, Issue:3

    Topics: Anesthesia, Intravenous; Cardiopulmonary Bypass; Child, Preschool; Female; Fentanyl; Humans; Infant;

1984
Plasma protein binding of fentanyl: the effect of hyperlipoproteinaemia and chronic renal failure.
    The Journal of pharmacy and pharmacology, 1982, Volume: 34, Issue:2

    Topics: Adult; Blood Proteins; Female; Fentanyl; Humans; Hyperlipoproteinemias; Kidney Failure, Chronic; Lip

1982
[Anesthesia in creating arteriovenous fistulae in chronic kidney failure patients].
    Khirurgiia, 1980, Volume: 33, Issue:4

    Topics: Adolescent; Adult; Anesthesia; Arteriovenous Shunt, Surgical; Droperidol; Drug Combinations; Female;

1980
Secondary hyperparathyroidism shortens the action of vecuronium in patients with chronic renal failure.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1995, Volume: 42, Issue:5 Pt 1

    Topics: Anesthesia, Inhalation; Anesthesia, Intravenous; Case-Control Studies; Electromyography; Female; Fen

1995
Case 2--1996. Anesthetic management of a patient with hemoglobin SS disease and mitral insufficiency for mitral valve repair.
    Journal of cardiothoracic and vascular anesthesia, 1996, Volume: 10, Issue:3

    Topics: Anemia, Sickle Cell; Anesthesia, Intravenous; Anesthetics, Intravenous; Cardiopulmonary Bypass; Eryt

1996
Subcutaneous fentanyl infusion in a patient with bowel obstruction and renal failure.
    Journal of pain and symptom management, 1997, Volume: 13, Issue:4

    Topics: Aged; Aged, 80 and over; Analgesics, Opioid; Female; Fentanyl; Humans; Injections, Subcutaneous; Int

1997
[The anesthetic management of patients in chronic renal failure for coronary artery bypass surgery without cardiopulmonary bypass].
    Masui. The Japanese journal of anesthesiology, 1997, Volume: 46, Issue:12

    Topics: Adult; Anesthesia; Cardiopulmonary Bypass; Coronary Artery Bypass; Coronary Disease; Fentanyl; Human

1997
[Anesthetic management for pericardial fenestration in a hypertrophic cardiomyopathy (HCM) patient with massive pericardial effusion].
    Masui. The Japanese journal of anesthesiology, 1999, Volume: 48, Issue:2

    Topics: Aged; Anesthesia, Intravenous; Anesthetics, Combined; Anesthetics, Intravenous; Atrial Fibrillation;

1999
[General anesthesia for a patient on hemodialysis with arteriosclerosis obliterans].
    Masui. The Japanese journal of anesthesiology, 2000, Volume: 49, Issue:11

    Topics: Anesthesia, General; Arteriosclerosis Obliterans; Blood Pressure; Carotid Arteries; Fentanyl; Humans

2000
Effects of cholestatic hepatic disease and chronic renal failure on alfentanil pharmacokinetics in children.
    Anesthesia and analgesia, 1989, Volume: 68, Issue:5

    Topics: Adolescent; Alfentanil; Child; Child, Preschool; Cholestasis; Fentanyl; Humans; Infant; Kidney Failu

1989
Postoperative respiratory depression and elevated sufentanil levels in a patient with chronic renal failure.
    Anesthesiology, 1985, Volume: 63, Issue:6

    Topics: Aged; Anesthesia, General; Anesthetics; Fentanyl; Humans; Kidney Failure, Chronic; Kinetics; Male; P

1985
Pharmacokinetics of sufentanil in adolescent patients with chronic renal failure.
    Anesthesia and analgesia, 1988, Volume: 67, Issue:3

    Topics: Adolescent; Child; Fentanyl; Half-Life; Humans; Kidney; Kidney Failure, Chronic; Sufentanil

1988
Pharmacokinetics of sufentanil in patients undergoing renal transplantation.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1988, Volume: 35, Issue:3 ( Pt 1)

    Topics: Adult; Blood Proteins; Fentanyl; Humans; Kidney Failure, Chronic; Kidney Transplantation; Male; Prot

1988
Alfentanil kinetics in renal insufficiency.
    European journal of clinical pharmacology, 1986, Volume: 30, Issue:2

    Topics: Adult; Aged; Alfentanil; Analgesics; Female; Fentanyl; Humans; Kidney Failure, Chronic; Kinetics; Ma

1986
Pharmacokinetics of alfentanil in chronic renal failure.
    Anesthesia and analgesia, 1987, Volume: 66, Issue:1

    Topics: Adult; Alfentanil; Anesthetics; Blood Proteins; Fentanyl; Glycoproteins; Half-Life; Humans; Injectio

1987
Cardiorespiratory effects of anaesthesia with morphine or fentanyl in chronic renal failure and cerebral toxicity after morphine.
    British journal of anaesthesia, 1971, Volume: 43, Issue:11

    Topics: Anesthesia, Intravenous; Blood Pressure; Blood Volume; Carbon Dioxide; Cardiac Output; Coma; Fentany

1971
Circulatory effects of analgesic and neuroleptic drugs in patients with chronic renal failure undergoing maintenance dialysis.
    British journal of anaesthesia, 1970, Volume: 42, Issue:6

    Topics: Analgesics; Benperidol; Blood Circulation; Blood Pressure; Cardiac Output; Fentanyl; Heart Rate; Hum

1970
Brachial plexus block in uremic patients.
    Polish medical journal, 1971, Volume: 10, Issue:2

    Topics: Anesthesia, Local; Anesthesia, Spinal; Arteriovenous Shunt, Surgical; Axilla; Brachial Plexus; Fenta

1971