fentanyl has been researched along with Cardiovascular Stroke in 47 studies
Fentanyl: A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078)
fentanyl : A monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of N-phenyl-1-(2-phenylethyl)piperidin-4-amine with propanoic acid.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In this retrospective study, the effect on ventricular arrhythmia incidence during ligation and infarct size following in vivo reperfusion of two anaesthetic regimens, sufentanil-medetomidine (SM) and fentanyl/fluanisone-midazolam (FFM) was evaluated in rats." | 7.88 | Sufentanil-medetomidine anaesthesia compared with fentanyl/fluanisone-midazolam is associated with fewer ventricular arrhythmias and death during experimental myocardial infarction in rats and limits infarct size following reperfusion. ( Flecknell, P; Kramer, K; Krijnen, PAJ; Meyer, KW; Niessen, HWM; Piek, JJ; Ter Horst, EN; van der Laan, AM, 2018) |
| "We examined the effects of intravenous anesthetics (thiopental, fentanyl and morphine) on the ventricular activation in a canine myocardial infarction model." | 7.68 | Effects of intravenous anesthetics, thiopental, fentanyl, and morphine on ventricular delayed activation in a canine myocardial infarction model. ( Hashimoto, H; Ikeda, K; Imamura, S; Nakashima, M, 1993) |
| "We compared the action of alfentanil on experimental myocardial infarction size with two widely used anesthetic drugs: fentanyl and halothane." | 7.67 | The effect of alfentanil on experimental myocardial infarction size: a comparison with fentanyl and halothane. ( Birkhan, J; Finberg, JP; Lichtig, H; Markiewicz, W, 1986) |
| "Myocardial infarction is a rare and lethal event during pregnancy with an incidence of 1 in 10,000 pregnancies." | 5.28 | Anaesthetic management of a parturient with myocardial infarction related to cocaine use. ( Chen, K; Forrester, RM; Glassenberg, R; Liu, SS; Murphy, GS, 1992) |
| " Cardiac morbidity (postoperative myocardial ischemia, postoperative myocardial infarction, and perioperative sympathoadrenal stress response), respiratory morbidity (postextubation apnea, alveolar-arterial oxygen gradient, pulmonary shunting, oxygen consumption, atelectasis, and reintubation), hemodynamic values and vasoactive medication requirements, intraoperative awareness, postoperative cognitive function, 30 day mortality, and intensive care unit and hospital lengths of stay were compared between the two groups." | 5.08 | Morbidity outcome in early versus conventional tracheal extubation after coronary artery bypass grafting: a prospective randomized controlled trial. ( Asokumar, B; Carroll, J; Cheng, DC; David, T; Karski, J; Mickle, D; Nierenberg, H; Peniston, C; Raveendran, G; Roger, S; Sandler, A; Tong, J; Zelovitsky, J, 1996) |
| " In this retrospective study, the effect on ventricular arrhythmia incidence during ligation and infarct size following in vivo reperfusion of two anaesthetic regimens, sufentanil-medetomidine (SM) and fentanyl/fluanisone-midazolam (FFM) was evaluated in rats." | 3.88 | Sufentanil-medetomidine anaesthesia compared with fentanyl/fluanisone-midazolam is associated with fewer ventricular arrhythmias and death during experimental myocardial infarction in rats and limits infarct size following reperfusion. ( Flecknell, P; Kramer, K; Krijnen, PAJ; Meyer, KW; Niessen, HWM; Piek, JJ; Ter Horst, EN; van der Laan, AM, 2018) |
| "We investigated the involvement of central and peripheral opioid receptors (OR) in the cardioprotective effects of fentanyl (FENT) in a model of myocardial ischemia/reperfusion injury associated with pharmacologically induced sympathetic overactivity in anesthetized rabbits." | 3.73 | Pharmacologic evidence for the involvement of central and peripheral opioid receptors in the cardioprotective effects of fentanyl. ( Lessa, MA; Tibiriçá, E, 2006) |
| "We examined the effects of intravenous anesthetics (thiopental, fentanyl and morphine) on the ventricular activation in a canine myocardial infarction model." | 3.68 | Effects of intravenous anesthetics, thiopental, fentanyl, and morphine on ventricular delayed activation in a canine myocardial infarction model. ( Hashimoto, H; Ikeda, K; Imamura, S; Nakashima, M, 1993) |
| "We compared the action of alfentanil on experimental myocardial infarction size with two widely used anesthetic drugs: fentanyl and halothane." | 3.67 | The effect of alfentanil on experimental myocardial infarction size: a comparison with fentanyl and halothane. ( Birkhan, J; Finberg, JP; Lichtig, H; Markiewicz, W, 1986) |
| "Fentanyl (0." | 1.40 | Spinal neuronal NOS activation mediates intrathecal fentanyl preconditioning induced remote cardioprotection in rats. ( Dong, C; Hu, J; Lu, Y; Zhang, Y, 2014) |
| "Myocardial infarction is rare during pregnancy." | 1.31 | [Myocardial infarction, pregnancy and anesthesia]. ( Diar, N; Rezig, K; Walcker, JL, 2000) |
| "Because the patient developed acute renal failure and furosemide did not show diuretic effect, hemodialysis was used." | 1.30 | [Perioperative management for acute abdominal aortic obstruction in a patient with acute myocardial reinfarction associated with acute renal failure]. ( Ishiyama, T; Tsujitou, T, 1997) |
| "Myocardial infarction is a rare and lethal event during pregnancy with an incidence of 1 in 10,000 pregnancies." | 1.28 | Anaesthetic management of a parturient with myocardial infarction related to cocaine use. ( Chen, K; Forrester, RM; Glassenberg, R; Liu, SS; Murphy, GS, 1992) |
| "Halothane produced lower blood pressures, fewer ECG changes, and lower heart rates than those seen in conscious or fentanyl anesthetized rats." | 1.27 | Effects of halothane anesthesia compared with fentanyl anesthesia and no anesthesia during coronary ligation in rats. ( Augereau, P; MacLeod, BA; Walker, MJ, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 32 (68.09) | 18.7374 |
| 1990's | 7 (14.89) | 18.2507 |
| 2000's | 6 (12.77) | 29.6817 |
| 2010's | 2 (4.26) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ter Horst, EN | 1 |
| Krijnen, PAJ | 1 |
| Flecknell, P | 1 |
| Meyer, KW | 1 |
| Kramer, K | 1 |
| van der Laan, AM | 1 |
| Piek, JJ | 1 |
| Niessen, HWM | 1 |
| Lu, Y | 1 |
| Hu, J | 1 |
| Zhang, Y | 1 |
| Dong, C | 1 |
| Palomero Rodríguez, MA | 1 |
| Suarez Gonzalo, L | 1 |
| Villar Alvarez, F | 1 |
| Varela Crespo, C | 1 |
| Moreno Gomez Limon, I | 1 |
| Criado Jimenez, A | 1 |
| Gross, ER | 2 |
| Peart, JN | 1 |
| Hsu, AK | 2 |
| Auchampach, JA | 1 |
| Gross, GJ | 2 |
| Lessa, MA | 1 |
| Tibiriçá, E | 1 |
| MacLeod, BA | 1 |
| Augereau, P | 1 |
| Walker, MJ | 1 |
| Furuya, Y | 2 |
| Tanaka, S | 2 |
| Yokoyama, S | 1 |
| Nagara, M | 2 |
| Ohe, Y | 2 |
| Fujita, M | 2 |
| Zakin, AM | 1 |
| Cheoban, VN | 1 |
| Hashimoto, H | 1 |
| Imamura, S | 1 |
| Ikeda, K | 1 |
| Nakashima, M | 1 |
| Cheng, DC | 1 |
| Karski, J | 1 |
| Peniston, C | 1 |
| Asokumar, B | 1 |
| Raveendran, G | 1 |
| Carroll, J | 1 |
| Nierenberg, H | 1 |
| Roger, S | 1 |
| Mickle, D | 1 |
| Tong, J | 1 |
| Zelovitsky, J | 1 |
| David, T | 1 |
| Sandler, A | 1 |
| Ishiyama, T | 1 |
| Tsujitou, T | 1 |
| Kato, R | 1 |
| Foëx, P | 1 |
| Rezig, K | 1 |
| Diar, N | 1 |
| Walcker, JL | 1 |
| Schaer, H | 1 |
| Liu, SS | 1 |
| Forrester, RM | 1 |
| Murphy, GS | 1 |
| Chen, K | 1 |
| Glassenberg, R | 1 |
| Noble, WH | 1 |
| Baker, A | 1 |
| Côté, D | 1 |
| Martin, R | 1 |
| Tétrault, JP | 1 |
| Tuman, KJ | 1 |
| McCarthy, RJ | 1 |
| el-Ganzouri, AR | 1 |
| Spiess, BD | 1 |
| Ivankovich, AD | 1 |
| Butterworth, JF | 1 |
| Bean, VE | 1 |
| Royster, RL | 1 |
| Hess, L | 2 |
| Vrána, M | 2 |
| Vránová, Z | 2 |
| Fejfar, Z | 2 |
| Wood, M | 1 |
| Markiewicz, W | 1 |
| Finberg, JP | 1 |
| Lichtig, H | 1 |
| Birkhan, J | 1 |
| Hunt, GB | 1 |
| Ross, DL | 1 |
| Vender, JS | 1 |
| Matthew, EB | 1 |
| Silverman, IM | 1 |
| Konowitz, H | 1 |
| Dau, PC | 1 |
| Godet, G | 1 |
| Coriat, P | 1 |
| Baron, JF | 1 |
| Bertrand, M | 1 |
| Diquet, B | 1 |
| Sebag, C | 1 |
| Viars, P | 1 |
| Mergner, GW | 1 |
| Mergner, WJ | 1 |
| Stoiko, M | 1 |
| Kipshidze, NN | 1 |
| Chapidze, GE | 1 |
| Marsagishvili, LA | 1 |
| Naess, K | 1 |
| Vermeire, P | 1 |
| van den Bogaert, P | 1 |
| Bossaert, L | 1 |
| Heyndrickx, G | 1 |
| van Durme, JP | 1 |
| Pannier, R | 1 |
| Zminkowska, U | 1 |
| Woyda, J | 1 |
| Lukicheva, TI | 1 |
| Litovchenko, VS | 1 |
| Freye, E | 1 |
| Wakabayashi, A | 1 |
| Connolly, JE | 1 |
| Stemmer, EA | 1 |
| Nakamura, Y | 1 |
| Dyduszynski, A | 1 |
| Luczak, J | 2 |
| Gvatua, NA | 1 |
| Kravtsov, VL | 1 |
| Tsyganii, AA | 1 |
| Pomerantsev, IuV | 1 |
| Ianovskii, AD | 1 |
| Szulc, EJ | 1 |
| Miturzyńska-Stryjecka, H | 1 |
| Widomska-Czekajska, T | 1 |
| Tevelenok, IuA | 1 |
| Brodzińska, K | 1 |
| Skubiszyńska, A | 1 |
| Szmydt, W | 1 |
| Kedra, M | 1 |
| Pitera, A | 1 |
| Popov, VG | 1 |
| Syrkin, AL | 1 |
| Flerov, EV | 1 |
| Lazutin, VK | 1 |
| Lazebnik, LB | 1 |
| Kaniak, J | 2 |
| Suchnicka, R | 2 |
| Zagrobelny, Z | 2 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Prospective Study Comparing the Efficacy and Safety of 100 mcg and 200 mcg of Intranasal Fentanyl Pectin Spray as an Analgesic in Adult Males Undergoing Outpatient Cystoscopic Procedures[NCT01756651] | Phase 1 | 20 participants (Actual) | Interventional | 2013-02-28 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for fentanyl and Cardiovascular Stroke
| Article | Year |
|---|---|
Plasma drug binding: implications for anesthesiologists.
Topics: Age Factors; Alfentanil; Alprenolol; Anesthesia; Anesthetics; Blood Proteins; Bupivacaine; Burns; Ca | 1986 |
[Management of cardiogenic shock].
Topics: Bradycardia; Dextrans; Digitalis Glycosides; Droperidol; Electric Countershock; Electroconvulsive Th | 1973 |
7 trials available for fentanyl and Cardiovascular Stroke
| Article | Year |
|---|---|
Thoracic epidural anesthesia decreases C-reactive protein levels in patients undergoing elective coronary artery bypass graft surgery with cardiopulmonary bypass.
Topics: Aged; Analgesia, Epidural; Anesthesia Recovery Period; Anesthesia, Epidural; Anesthesia, General; An | 2008 |
Morbidity outcome in early versus conventional tracheal extubation after coronary artery bypass grafting: a prospective randomized controlled trial.
Topics: Aged; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Apnea; Catecholamines; | 1996 |
Haemodynamic interactions of muscle relaxants and sufentanil in coronary artery surgery.
Topics: Adrenergic beta-Antagonists; Aged; Anesthetics; Atracurium; Blood Pressure; Cardiac Output; Central | 1991 |
Sufentanil is preferable to etomidate during rapid-sequence anesthesia induction for aortocoronary bypass surgery.
Topics: Anesthesia, Intravenous; Anesthetics; Blood Pressure; Coronary Artery Bypass; Coronary Disease; Drug | 1989 |
An experimental contribution to the treatment of acute myocardial infarction.
Topics: Adult; Analgesics; Animals; Benzodiazepines; Clinical Trials as Topic; Dogs; Drug Evaluation; Electr | 1987 |
Prevention of intraoperative myocardial ischemia during noncardiac surgery with intravenous diltiazem: a randomized trial versus placebo.
Topics: Aged; Diltiazem; Double-Blind Method; Drug Evaluation; Electrocardiography; Fentanyl; Flunitrazepam; | 1987 |
[Analgesic effects and hemodynamic and respiratory repercussions of the fentanyl-droperidol combination in the acute stage of myocardial infarction].
Topics: Adult; Aged; Benperidol; Blood Gas Analysis; Blood Pressure; Butyrophenones; Cardiac Output; Clinica | 1973 |
38 other studies available for fentanyl and Cardiovascular Stroke
| Article | Year |
|---|---|
Sufentanil-medetomidine anaesthesia compared with fentanyl/fluanisone-midazolam is associated with fewer ventricular arrhythmias and death during experimental myocardial infarction in rats and limits infarct size following reperfusion.
Topics: Anesthetics, Combined; Animals; Arrhythmias, Cardiac; Butyrophenones; Fentanyl; Male; Medetomidine; | 2018 |
Spinal neuronal NOS activation mediates intrathecal fentanyl preconditioning induced remote cardioprotection in rats.
Topics: Adjuvants, Anesthesia; Analgesics, Opioid; Animals; Blood Pressure; Cardiotonic Agents; Fentanyl; He | 2014 |
Extending the cardioprotective window using a novel delta-opioid agonist fentanyl isothiocyanate via the PI3-kinase pathway.
Topics: Analgesics, Opioid; Animals; Blood Pressure; Disease Models, Animal; Fentanyl; Heart Rate; Hemodynam | 2005 |
The JAK/STAT pathway is essential for opioid-induced cardioprotection: JAK2 as a mediator of STAT3, Akt, and GSK-3 beta.
Topics: Animals; Cardiotonic Agents; Cell Line; Enzyme Inhibitors; Fentanyl; Glycogen Synthase Kinase 3; Gly | 2006 |
Pharmacologic evidence for the involvement of central and peripheral opioid receptors in the cardioprotective effects of fentanyl.
Topics: Animals; Arrhythmias, Cardiac; Cardiotonic Agents; Dose-Response Relationship, Drug; Female; Fentany | 2006 |
Effects of halothane anesthesia compared with fentanyl anesthesia and no anesthesia during coronary ligation in rats.
Topics: Anesthesia, General; Animals; Arrhythmias, Cardiac; Blood Pressure; Coronary Disease; Coronary Vesse | 1983 |
[Effects of morphine anesthesia and thalamonal anesthesia on myocardial blood flow after coronary artery ligation (author's transl)].
Topics: Anesthesia, Intravenous; Animals; Coronary Circulation; Dogs; Droperidol; Drug Combinations; Fentany | 1982 |
[Analgesia in the acute period of myocardial infarct under hemodynamic and respiratory functional control].
Topics: Adult; Aged; Dipyrone; Droperidol; Electronarcosis; Female; Fentanyl; Hemodynamics; Humans; Male; Mi | 1981 |
[Effects of halothane, morphine and thalamonal anesthesia on myocardial ischemia (author's transl)].
Topics: Anesthesia, Inhalation; Animals; Coronary Circulation; Dogs; Droperidol; Drug Combinations; Fentanyl | 1980 |
Effects of intravenous anesthetics, thiopental, fentanyl, and morphine on ventricular delayed activation in a canine myocardial infarction model.
Topics: Action Potentials; Animals; Blood Pressure; Disease Models, Animal; Dogs; Electrocardiography; Fenta | 1993 |
[Perioperative management for acute abdominal aortic obstruction in a patient with acute myocardial reinfarction associated with acute renal failure].
Topics: Acute Disease; Acute Kidney Injury; Aged; Anesthesia, General; Anesthetics, Combined; Aorta, Abdomin | 1997 |
Fentanyl reduces infarction but not stunning via delta-opioid receptors and protein kinase C in rats.
Topics: Analgesics, Opioid; Animals; Coloring Agents; Fentanyl; Male; Myocardial Infarction; Myocardial Stun | 2000 |
[Myocardial infarction, pregnancy and anesthesia].
Topics: Adrenergic beta-Antagonists; Adult; Analgesia, Obstetrical; Analgesia, Patient-Controlled; Analgesic | 2000 |
[The coronary patient, a challenge to the anesthesist].
Topics: Adrenergic beta-Antagonists; Anesthesia, General; Angina Pectoris; Coronary Disease; Etomidate; Fent | 1977 |
Anaesthetic management of a parturient with myocardial infarction related to cocaine use.
Topics: Adult; Anesthesia, Intravenous; Anesthesia, Obstetrical; Crack Cocaine; Female; Fentanyl; Humans; La | 1992 |
MAO inhibitors and coronary artery surgery: a patient death.
Topics: Acidosis; Anesthesia, Intravenous; Angina, Unstable; Cause of Death; Coronary Artery Bypass; Fentany | 1992 |
Sufentanil-midazolam anesthesia for coronary artery surgery.
Topics: Adrenergic beta-Antagonists; Anesthesia, Intravenous; Anesthetics; Blood Pressure; Cardiac Output; C | 1990 |
The electrostabilizing effect of a combination of midazolam and fentanyl: an experimental study in the dog.
Topics: Animals; Blood Pressure; Dogs; Drug Combinations; Electrocardiography; Fentanyl; Heart Conduction Sy | 1989 |
The effect of alfentanil on experimental myocardial infarction size: a comparison with fentanyl and halothane.
Topics: Alfentanil; Anesthetics; Animals; Fentanyl; Halothane; Male; Myocardial Infarction; Rats; Rats, Inbr | 1986 |
Comparison of effects of three anesthetic agents on induction of ventricular tachycardia in a canine model of myocardial infarction.
Topics: Animals; Dogs; Droperidol; Drug Combinations; Electric Stimulation; Electrophysiology; Fentanyl; Hal | 1988 |
Heparin-associated thrombocytopenia: alternative managements.
Topics: Coronary Artery Bypass; Fentanyl; Heparin; Humans; Male; Middle Aged; Myocardial Infarction; Plasmap | 1986 |
Anesthetics influence myocardial infarct size.
Topics: Anesthetics; Animals; Coronary Circulation; Coronary Vessels; Dogs; Fentanyl; Halothane; Heart Rate; | 1985 |
[Experimental basis for using long-term controlled artificial pulmonary ventilation in acute myocardial infarction].
Topics: Acid-Base Equilibrium; Acute Disease; Anesthesia, General; Animals; Dogs; Ether; Fentanyl; Hemodynam | 1985 |
[Petidin as a histamine releases--how much analgesics in heart infarct? (Fortralin and Leptanal)].
Topics: Blood Pressure; Fentanyl; Histamine Release; Humans; Meperidine; Myocardial Infarction; Pentazocine | 1970 |
[Value of neuroleptoanalgesia II in the treatment of pain during myocardial infarct].
Topics: Acute Disease; Adult; Aged; Droperidol; Female; Fentanyl; Humans; Male; Middle Aged; Myocardial Infa | 1974 |
[Effect of anesthesia with preparations for neuroleptanalgesia type II (phentanyl and droperidol) on the concentration of catecholamines in the blood plasma of patients with macrofocal myocardial infarct].
Topics: Adult; Aged; Droperidol; Epinephrine; Female; Fentanyl; Humans; Male; Middle Aged; Myocardial Infarc | 1974 |
Effect of high doses of Fentanyl on myocardial infarction and cardiogenic shock in the dog.
Topics: Animals; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Drug Evaluation, Preclinica | 1974 |
Clinical experience with heparinless venoarterial bypass without oxygenation for the treatment of acute cardiogenic shock.
Topics: Adult; Aged; Autopsy; Blood Pressure; Cardiac Output; Central Venous Pressure; Coronary Artery Bypas | 1974 |
[Clinical evaluation of fentanyl and dehydrobenzperidol in acute myocardial infarct].
Topics: Acute Disease; Adult; Aged; Benperidol; Butyrophenones; Droperidol; Evaluation Studies as Topic; Fem | 1972 |
[Some aspects of the use of prolonged neuroplegia in treating acute myocardial infarct].
Topics: Acute Disease; Aminopyrine; Analgesics; Anti-Arrhythmia Agents; Anticoagulants; Autonomic Agents; Be | 1973 |
[Clinical evaluation of agents used in type II neuroleptoanalgesia (NLA II) in acute myocardial infarct].
Topics: Acute Disease; Adult; Aged; Droperidol; Drug Synergism; Female; Fentanyl; Humans; Male; Middle Aged; | 1973 |
The effect of neuroleptanalgesia II on acid-base balance and blood oxygenation in patients with myocardial infarction.
Topics: Acid-Base Equilibrium; Adult; Aged; Benperidol; Blood; Carbon Dioxide; Fentanyl; Humans; Hydrogen-Io | 1971 |
[Use of drugs for neuroleptoanalgesia in the acute period of a myocardial infarct].
Topics: Acid-Base Equilibrium; Acute Disease; Aged; Benperidol; Blood Volume; Carbon Dioxide; Female; Fentan | 1971 |
Neuroleptanalgesia II in recent myocardial infarction.
Topics: Adult; Aged; Anxiety; Butyrophenones; Female; Fentanyl; Humans; Injections, Intravenous; Male; Middl | 1969 |
[Neuroleptoanalgesia in management of pain in myocardial infarct].
Topics: Adult; Aged; Benperidol; Female; Fentanyl; Humans; Male; Middle Aged; Myocardial Infarction; Nalorph | 1970 |
[Talamonal therapy of patients with lung edema and myocardial infarct].
Topics: Adult; Aged; Benperidol; Female; Fentanyl; Humans; Male; Middle Aged; Myocardial Infarction; Pulmona | 1970 |
Treatment of myocardial infarction with agents used in type II (NLA II) neuroleptoanalgesia.
Topics: Benperidol; Fentanyl; Humans; Male; Middle Aged; Myocardial Infarction; Neuroleptanalgesia | 1969 |
[Treatment of myocardial infarction with agents used in neuroleptoanalgesia type II (NLA II)].
Topics: Adult; Aged; Benperidol; Fentanyl; Humans; Male; Middle Aged; Myocardial Infarction; Neuroleptanalge | 1969 |