fentanyl has been researched along with Carcinoma in 14 studies
Fentanyl: A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078)
fentanyl : A monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of N-phenyl-1-(2-phenylethyl)piperidin-4-amine with propanoic acid.
Carcinoma: A malignant neoplasm made up of epithelial cells tending to infiltrate the surrounding tissues and give rise to metastases. It is a histological type of neoplasm and not a synonym for cancer.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In this prospective, randomized, placebo-controlled, double-blinded clinical trial we tested the hypothesis that preemptive analgesia with bupivacaine applied in the area of the surgical incision in patients undergoing mastectomy for breast cancer would reduce post-operative acute pain and would reduce the amount of analgesics used during surgery and in the post-operative period." | 9.15 | A randomized, double-blind, placebo-controlled trial of preemptive analgesia with bupivacaine in patients undergoing mastectomy for carcinoma of the breast. ( Irga, N; Jaskiewicz, J; Jaworski, R; Smietanska, I; Wujtewicz, M; Zielinski, J, 2011) |
| "This study evaluated the efficacy, safety, and quality of life (QoL) measure of transdermal fentanyl (TDF) for moderate-to-severe pain due to oral mucositis caused by chemoradiotherapy in patients with advanced nasopharyngeal carcinoma (NPC)." | 7.80 | Transdermal fentanyl for pain due to chemoradiotherapy-induced oral mucositis in nasopharyngeal cancer patients: evaluating efficacy, safety, and improvement in quality of life. ( Feng, HX; Guo, SP; He, ZY; Li, FY; Sun, JY; Wu, SG; Wu, YJ; Zhou, J, 2014) |
| "We experienced a patient with an ileal artificial anus who suffered from abdominal pain caused by peritoneal dissemination of ovarian cancer, for which slow-release oxycodone was ineffective, but fentanyl patch proved effective." | 7.77 | [A case of pain management using transdermal fentanyl patches for peritoneal carcinomatosis in a patient with small intestine stoma]. ( Iwazaki, M; Masuda, R; Mikami, M; Nishiumi, N; Saito, Y; Tokuda, Y; Yoshino, K, 2011) |
| "In this prospective, randomized, placebo-controlled, double-blinded clinical trial we tested the hypothesis that preemptive analgesia with bupivacaine applied in the area of the surgical incision in patients undergoing mastectomy for breast cancer would reduce post-operative acute pain and would reduce the amount of analgesics used during surgery and in the post-operative period." | 5.15 | A randomized, double-blind, placebo-controlled trial of preemptive analgesia with bupivacaine in patients undergoing mastectomy for carcinoma of the breast. ( Irga, N; Jaskiewicz, J; Jaworski, R; Smietanska, I; Wujtewicz, M; Zielinski, J, 2011) |
| "This study evaluated the efficacy, safety, and quality of life (QoL) measure of transdermal fentanyl (TDF) for moderate-to-severe pain due to oral mucositis caused by chemoradiotherapy in patients with advanced nasopharyngeal carcinoma (NPC)." | 3.80 | Transdermal fentanyl for pain due to chemoradiotherapy-induced oral mucositis in nasopharyngeal cancer patients: evaluating efficacy, safety, and improvement in quality of life. ( Feng, HX; Guo, SP; He, ZY; Li, FY; Sun, JY; Wu, SG; Wu, YJ; Zhou, J, 2014) |
| "We experienced a patient with an ileal artificial anus who suffered from abdominal pain caused by peritoneal dissemination of ovarian cancer, for which slow-release oxycodone was ineffective, but fentanyl patch proved effective." | 3.77 | [A case of pain management using transdermal fentanyl patches for peritoneal carcinomatosis in a patient with small intestine stoma]. ( Iwazaki, M; Masuda, R; Mikami, M; Nishiumi, N; Saito, Y; Tokuda, Y; Yoshino, K, 2011) |
| "We compared the intensity of postoperative pain experienced by patients who received conventional open thyroidectomy (n = 45) versus those who underwent robotic thyroidectomy (n = 45)." | 2.78 | A comparison of postoperative pain after conventional open thyroidectomy and transaxillary single-incision robotic thyroidectomy: a prospective study. ( Chung, WY; Hong, JY; Jeong, JJ; Kang, SW; Lee, J; Park, JH; Ryu, HR, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (28.57) | 18.2507 |
| 2000's | 2 (14.29) | 29.6817 |
| 2010's | 8 (57.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ryu, HR | 1 |
| Lee, J | 1 |
| Park, JH | 1 |
| Kang, SW | 1 |
| Jeong, JJ | 1 |
| Hong, JY | 1 |
| Chung, WY | 1 |
| Guo, SP | 1 |
| Wu, SG | 1 |
| Zhou, J | 1 |
| Feng, HX | 1 |
| Li, FY | 1 |
| Wu, YJ | 1 |
| Sun, JY | 1 |
| He, ZY | 1 |
| Jeyabalan, A | 1 |
| Medford, AR | 1 |
| Ahmed, S | 1 |
| Naumann, DN | 1 |
| Karandikar, S | 1 |
| Shin, S | 1 |
| Park, CH | 1 |
| Kim, HJ | 1 |
| Park, SH | 1 |
| Lee, SK | 1 |
| Yoo, YC | 1 |
| Dzambazovska-Trajkovska, V | 1 |
| Nojkov, J | 1 |
| Kartalov, A | 1 |
| Kuzmanovska, B | 1 |
| Spiroska, T | 1 |
| Seljmani, R | 1 |
| Trajkovski, G | 1 |
| Matevska-Geshkovska, N | 1 |
| Dimovski, A | 1 |
| Yoshino, K | 1 |
| Nishiumi, N | 1 |
| Masuda, R | 1 |
| Saito, Y | 1 |
| Iwazaki, M | 1 |
| Mikami, M | 1 |
| Tokuda, Y | 1 |
| Zielinski, J | 1 |
| Jaworski, R | 1 |
| Smietanska, I | 1 |
| Irga, N | 1 |
| Wujtewicz, M | 1 |
| Jaskiewicz, J | 1 |
| Ruppen, W | 1 |
| Ruesch, S | 1 |
| Shüpfer, G | 1 |
| Christen, P | 1 |
| Edinboro, LE | 1 |
| Poklis, A | 1 |
| Trautman, D | 1 |
| Lowry, S | 1 |
| Backer, R | 1 |
| Harvey, CM | 1 |
| Bleeker, CP | 1 |
| Bremer, RC | 1 |
| Dongelmans, DA | 1 |
| van Dongen, RT | 1 |
| Crul, BJ | 1 |
| Stoukides, CA | 1 |
| Stegman, M | 1 |
| Tsui, SL | 1 |
| Lee, TW | 1 |
| Chan, AS | 1 |
| Lo, JR | 1 |
| Patt, R | 1 |
| Jain, S | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Comparison of Controlled-release Oxycodone to Control Chemoradiotherapy-induced Moderate or Severe Oral Mucositis Pain in Nasopharyngeal Carcinoma Patients[NCT03045484] | 70 participants (Anticipated) | Interventional | 2016-05-31 | Recruiting | |||
| Pre-Emptive Analgesia in Ano-Rectal Surgery[NCT02402543] | 90 participants (Actual) | Interventional | 2014-06-30 | Completed | |||
| The Use of Liposomal Bupivacaine for Pain Control Following Mastectomy and Breast Reconstruction[NCT03722927] | Phase 4 | 3 participants (Actual) | Interventional | 2018-06-14 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Frequency of postoperative opioid related adverse effects within the first week of surgery will be recorded. This includes nausea, vomiting, pruritus, allergy, respiratory depression. (NCT03722927)
Timeframe: Postoperatively, 1 week
| Intervention | Participants (Count of Participants) |
|---|---|
| Bupivacaine Group | 0 |
| Liposomal Bupivacaine Group | 0 |
The length of stay for hospitalization after mastectomy and breast reconstruction will be recorded. (NCT03722927)
Timeframe: up to 47 Hours
| Intervention | days (Mean) |
|---|---|
| Bupivacaine Group | 1 |
| Liposomal Bupivacaine Group | 1 |
This will be measured by the number of doses within the first month postoperatively and recorded on pain medication daily diary kept by subject. (NCT03722927)
Timeframe: 1 Month
| Intervention | Number of morphine doses (Number) |
|---|---|
| Bupivacaine Group | 0 |
| Liposomal Bupivacaine Group | 20 |
Readmission rates to the hospital within 2 months after mastectomy and breast reconstruction will be recorded (NCT03722927)
Timeframe: Month 2
| Intervention | Participants (Count of Participants) |
|---|---|
| Bupivacaine Group | 0 |
| Liposomal Bupivacaine Group | 0 |
This will be measured every 12 hours for the first 48 hours postoperatively by the level of breast pain associated with arm movements while eating on a scale of 0-10 with higher scores denoting worse outcomes. (NCT03722927)
Timeframe: 48 hours
| Intervention | score on a scale (Mean) |
|---|---|
| 12 hours | |
| Bupivacaine Group | 4 |
This will be measured every 12 hours for the first 48 hours postoperatively by the level of breast pain associated with arm movements while eating on a scale of 0-10 with higher scores denoting worse outcomes. (NCT03722927)
Timeframe: 48 hours
| Intervention | score on a scale (Mean) | |||
|---|---|---|---|---|
| 12 hours | 24 hours | 36 hours | 48 hours | |
| Liposomal Bupivacaine Group | 3.5 | 4 | 3.5 | 2 |
3 trials available for fentanyl and Carcinoma
| Article | Year |
|---|---|
A comparison of postoperative pain after conventional open thyroidectomy and transaxillary single-incision robotic thyroidectomy: a prospective study.
Topics: Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Analysis of Variance; Carcinoma; Carcinoma, Pap | 2013 |
Patient satisfaction after endoscopic submucosal dissection under propofol-based sedation: a small premedication makes all the difference.
Topics: Adenoma; Aged; Anesthetics, Intravenous; Carcinoma; Conscious Sedation; Endoscopic Mucosal Resection | 2017 |
A randomized, double-blind, placebo-controlled trial of preemptive analgesia with bupivacaine in patients undergoing mastectomy for carcinoma of the breast.
Topics: Analgesia, Patient-Controlled; Anesthetics, Local; Breast Neoplasms; Bupivacaine; Carcinoma; Double- | 2011 |
A randomized, double-blind, placebo-controlled trial of preemptive analgesia with bupivacaine in patients undergoing mastectomy for carcinoma of the breast.
Topics: Analgesia, Patient-Controlled; Anesthetics, Local; Breast Neoplasms; Bupivacaine; Carcinoma; Double- | 2011 |
A randomized, double-blind, placebo-controlled trial of preemptive analgesia with bupivacaine in patients undergoing mastectomy for carcinoma of the breast.
Topics: Analgesia, Patient-Controlled; Anesthetics, Local; Breast Neoplasms; Bupivacaine; Carcinoma; Double- | 2011 |
A randomized, double-blind, placebo-controlled trial of preemptive analgesia with bupivacaine in patients undergoing mastectomy for carcinoma of the breast.
Topics: Analgesia, Patient-Controlled; Anesthetics, Local; Breast Neoplasms; Bupivacaine; Carcinoma; Double- | 2011 |
11 other studies available for fentanyl and Carcinoma
| Article | Year |
|---|---|
Transdermal fentanyl for pain due to chemoradiotherapy-induced oral mucositis in nasopharyngeal cancer patients: evaluating efficacy, safety, and improvement in quality of life.
Topics: Administration, Cutaneous; Adult; Carcinoma; Chemoradiotherapy; Female; Fentanyl; Humans; Male; Midd | 2014 |
Endobronchial ultrasound-guided transbronchial needle aspiration: patient satisfaction under light conscious sedation.
Topics: Anesthetics, Intravenous; Bronchoscopy; Carcinoma; Conscious Sedation; Endoscopic Ultrasound-Guided | 2014 |
Differences in screening vs non-screening colonoscopy: scope for improvement?
Topics: Adenoma; Adjuvants, Anesthesia; Aged; Anesthetics, Combined; Butylscopolammonium Bromide; Carcinoma; | 2016 |
Association of Single-Nucleotide Polymorhism C3435T in the ABCB1 Gene with Opioid Sensitivity in Treatment of Postoperative Pain.
Topics: Adult; Aged; Aged, 80 and over; Analgesics, Opioid; ATP Binding Cassette Transporter, Subfamily B; C | 2016 |
[A case of pain management using transdermal fentanyl patches for peritoneal carcinomatosis in a patient with small intestine stoma].
Topics: Administration, Cutaneous; Adult; Carcinoma; Fatal Outcome; Female; Fentanyl; Humans; Ileal Neoplasm | 2011 |
Propofol and questionable lack of sedation.
Topics: Alfentanil; Anesthetics, Intravenous; Atracurium; Blood Pressure; Carcinoma; Conscious Sedation; Dos | 2005 |
Fatal fentanyl intoxication following excessive transdermal application.
Topics: Administration, Cutaneous; Aged; Aged, 80 and over; Analgesics, Opioid; Carcinoma; Fatal Outcome; Fe | 1997 |
Inefficacy of high-dose transdermal fentanyl in a patient with neuropathic pain, a case report.
Topics: Administration, Cutaneous; Analgesia, Epidural; Analgesics, Opioid; Anesthetics, Local; Breast Neopl | 2001 |
Diffuse rash associated with transdermal fentanyl.
Topics: Administration, Cutaneous; Carcinoma; Drug Eruptions; Female; Fentanyl; Humans; Lung Neoplasms; Midd | 1992 |
High-frequency jet ventilation in the anesthetic management of a patient with tracheoesophageal fistula complicating carcinoma of the esophagus.
Topics: Aged; Carcinoma; Esophageal Neoplasms; Fentanyl; Hemodynamics; High-Frequency Jet Ventilation; Human | 1991 |
Epidural sufentanil for cancer pain.
Topics: Aged; Analgesia, Epidural; Analgesics; Carcinoma; Fentanyl; Humans; Infusion Pumps; Male; Pain; Rect | 1990 |