Page last updated: 2024-10-27

fentanyl and Cancer of Lung

fentanyl has been researched along with Cancer of Lung in 55 studies

Fentanyl: A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078)
fentanyl : A monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of N-phenyl-1-(2-phenylethyl)piperidin-4-amine with propanoic acid.

Research Excerpts

ExcerptRelevanceReference
"Our findings indicate the advantages of sedation with fentanyl and midazolam without oropharyngeal anesthesia for ultrathin bronchoscopy through nasal intubation."8.02Sedation with fentanyl and midazolam without oropharyngeal anesthesia compared with sedation with pethidine and midazolam with oropharyngeal anesthesia in ultrathin bronchoscopy for peripheral lung lesions. ( Chiba, H; Kamada, K; Mori, Y; Nakata, H; Sawai, T; Shijubou, N; Sumi, T; Yamada, Y, 2021)
" In a male patient with non-small cell lung cancer who received palliative radiotherapy, the hyperpigmentation related to radiotherapy was examined two months later except for fentanyl transdermal patch area."7.83Can fentanyl transdermal patches prevent the cutaneous hyperpigmentation related to radiotherapy in patients with cancer? ( Mutlu, H, 2016)
" We treated a 50s female with pain and dyspnea from bone metastasis and lymphangitis carcinomatosa after surgery for NSCLC in whom the optimal dosages of transdermal fentanyl (Durotep Patch) were determined by titration with fentanyl injection, and oxycodone hydrochloride (OxyContin) in a short period."7.76[Successful management of a patient with pain and dyspnea from bone metastasis and lymphangitis carcinomatosa after surgery for non-small cell lung cancer (NSCLC) in whom optimal dosages of transdermal fentanyl were determined by titration with fentanyl i ( Eguchi, K; Gika, M; Inoue, Y; Izawa, N; Nakayama, M; Takeuchi, K, 2010)
"To evaluate the efficacy and safety of oral transmucosal fentanyl citrate (OTFC) in terminally ill patients experiencing dyspnea."7.74Oral transmucosal fentanyl citrate for dyspnea in terminally ill patients: an observational case series. ( Gauna, AA; Kang, SK; Swatko, ER; Triano, ML; Vanston, VJ, 2008)
"These results suggest that steady-state serum concentrations are approached by the second dose of TTS(fentanyl) and that the kinetics are stable with repeated dosing."7.68Transdermal fentanyl for cancer pain. Repeated dose pharmacokinetics. ( Foley, KM; Gupta, SK; Inturrisi, CE; Lapin, J; Layman, M; Portenoy, RK; Southam, MA, 1993)
"Fentanyl is an appropriate drug because of its fast onset and short duration of action."6.45[Nasal application of fentanyl citrate as symptom control against breathlessness in palliative care--overview and case report]. ( Sitte, T, 2009)
"PCIA with sufentanil provides better efficacy of analgesia and sedation with lower incidence of nausea and vomiting than with fentanyl in postoperative patients with thoracotomy."5.12[Patient-controlled intravenous analgesia with sufentanil and fentanyl after thoracotomy: a comparative study]. ( Gu, MN; Lin, CS; Lu, G; Ruan, LY, 2006)
"Our findings indicate the advantages of sedation with fentanyl and midazolam without oropharyngeal anesthesia for ultrathin bronchoscopy through nasal intubation."4.02Sedation with fentanyl and midazolam without oropharyngeal anesthesia compared with sedation with pethidine and midazolam with oropharyngeal anesthesia in ultrathin bronchoscopy for peripheral lung lesions. ( Chiba, H; Kamada, K; Mori, Y; Nakata, H; Sawai, T; Shijubou, N; Sumi, T; Yamada, Y, 2021)
" In a male patient with non-small cell lung cancer who received palliative radiotherapy, the hyperpigmentation related to radiotherapy was examined two months later except for fentanyl transdermal patch area."3.83Can fentanyl transdermal patches prevent the cutaneous hyperpigmentation related to radiotherapy in patients with cancer? ( Mutlu, H, 2016)
" Postoperative pain levels after hybrid VATS, and the impact of postoperative continuous infusion of fentanyl on postoperative pain levels and the incidence of postoperative nausea and vomiting (PONV) were examined."3.81[Postoperative Pain after Hybrid Video-assisted Thoracic Surgery]. ( Fukuda, K; Mizota, T; Murata, Y, 2015)
" We treated a 50s female with pain and dyspnea from bone metastasis and lymphangitis carcinomatosa after surgery for NSCLC in whom the optimal dosages of transdermal fentanyl (Durotep Patch) were determined by titration with fentanyl injection, and oxycodone hydrochloride (OxyContin) in a short period."3.76[Successful management of a patient with pain and dyspnea from bone metastasis and lymphangitis carcinomatosa after surgery for non-small cell lung cancer (NSCLC) in whom optimal dosages of transdermal fentanyl were determined by titration with fentanyl i ( Eguchi, K; Gika, M; Inoue, Y; Izawa, N; Nakayama, M; Takeuchi, K, 2010)
"To evaluate the efficacy and safety of oral transmucosal fentanyl citrate (OTFC) in terminally ill patients experiencing dyspnea."3.74Oral transmucosal fentanyl citrate for dyspnea in terminally ill patients: an observational case series. ( Gauna, AA; Kang, SK; Swatko, ER; Triano, ML; Vanston, VJ, 2008)
"These results suggest that steady-state serum concentrations are approached by the second dose of TTS(fentanyl) and that the kinetics are stable with repeated dosing."3.68Transdermal fentanyl for cancer pain. Repeated dose pharmacokinetics. ( Foley, KM; Gupta, SK; Inturrisi, CE; Lapin, J; Layman, M; Portenoy, RK; Southam, MA, 1993)
"The degree of postoperative pain was assessed on the total dose of additional analgesics administered, a visual analog scale (VAS), a verbal pain score at rest (VPS-R) and on movement (VPS-M), from the day of surgery to the 2nd postoperative day (2 POD)."2.72The efficacy of epidural analgesia after video-assisted thoracoscopic surgery: a randomized control study. ( Iwatani, K; Kobayashi, H; Mori, T; Nomori, H; Terasaki, H; Yoshimoto, K; Yoshioka, M, 2006)
"Fentanyl is an appropriate drug because of its fast onset and short duration of action."2.45[Nasal application of fentanyl citrate as symptom control against breathlessness in palliative care--overview and case report]. ( Sitte, T, 2009)
"The postoperative pain was measured by visual analog scale (VAS)."1.51Correlation of P2RX7 gene rs1718125 polymorphism with postoperative fentanyl analgesia in patients with lung cancer. ( Chai, Q; Li, W; Ma, J; Tan, X; Zhang, K, 2019)
"Midazolam was administered to all patients."1.46Bronchoscopic diagnosis of peripheral pulmonary lung cancer employing sedation with fentanyl and midazolam. ( Ando, C; Fujiwara, K; Iwamoto Md, Y; Minami, D; Nakasuka, T; Sato, K; Sato, T; Shibayama, T; Yonei Md PhD, T, 2017)
" The median intraoperative fentanyl equivalents dosage was 10."1.40A retrospective analysis of the effect of intraoperative opioid dose on cancer recurrence after non-small cell lung cancer resection. ( Cata, JP; Engle, M; Feng, L; Gottumukkala, V; Keerty, D; Keerty, V; Mehran, JR; Norman, PH, 2014)
"Additionally, gabapentin was given for neuropathic pain uncontrolled by opioids."1.37[Oxycodone and pregabalin using transdermal fentanyl patch provided relief of symptoms for postherpetic neuropathic pain in a patient with non-small cell lung cancer]. ( Ando, A; Nishimura, D; Shibahara, H; Suzuki, S; Uematsu, N, 2011)
"Buprenorphine (0."1.34Buprenorphine ameliorates the effect of surgery on hypothalamus-pituitary-adrenal axis, natural killer cell activity and metastatic colonization in rats in comparison with morphine or fentanyl treatment. ( Franchi, S; Panerai, AE; Sacerdote, P, 2007)
"Fentanyl was discontinued, fluids were restricted, and 3% saline was started."1.31Fentanyl-associated syndrome of inappropriate antidiuretic hormone secretion. ( Afrin, LB; Hall, PD; Kokko, H, 2002)
" In addition, the total daily dose of ketorolac was reduced following a change from intermittent bolus dosing to a continuous infusion."1.30Prolonged central intravenous ketorolac continuous infusion in a cancer patient with intractable bone pain. ( Gordon, RL, 1998)
" Recommendations for managing opioid-induced muscle hyperactivity include reduction of the opioid dosage and/or administration of clonazepam therapy."1.29Opioid-induced muscle activity: implications for managing chronic pain. ( Levitt, R; Steen, PD; Sylvester, RK, 1995)

Research

Studies (55)

TimeframeStudies, this research(%)All Research%
pre-19903 (5.45)18.7374
1990's7 (12.73)18.2507
2000's21 (38.18)29.6817
2010's20 (36.36)24.3611
2020's4 (7.27)2.80

Authors

AuthorsStudies
Chung, HS1
Pak, K1
Lee, G1
Eom, JS1
Ohashi, K1
Suzuki, H1
Sata, Y1
Tanaka, K1
Yamamoto, T1
Sakairi, Y1
Wada, H1
Nakajima, T1
Nozaki-Taguchi, N1
Isono, S1
Shiko, Y1
Kawasaki, Y1
Yoshino, I1
Liu, W1
Chen, Y1
Xu, W1
Wang, W1
Tang, L1
Xia, R1
Zhu, Q1
Sumi, T1
Kamada, K1
Sawai, T1
Shijubou, N1
Yamada, Y1
Nakata, H1
Mori, Y1
Chiba, H1
Minami, D1
Nakasuka, T1
Ando, C1
Iwamoto Md, Y1
Sato, K1
Fujiwara, K1
Shibayama, T1
Yonei Md PhD, T1
Sato, T1
Conte, SC1
Spagnol, G1
Confalonieri, M1
Brizi, B1
Ma, J1
Li, W1
Chai, Q1
Tan, X1
Zhang, K1
Cata, JP3
Bauer, M1
Sokari, T1
Ramirez, MF1
Mason, D1
Plautz, G1
Kurz, A1
Gottumukkala, V2
Thakar, D1
Keerty, D2
Gebhardt, R1
Liu, DD1
Keerty, V1
Feng, L1
Norman, PH1
Mehran, JR1
Engle, M1
Kajiyama, S1
Miyoshi, H1
Kato, T1
Kawamoto, M1
Jeyabalan, A1
Medford, AR1
Mutlu, H1
Murata, Y1
Mizota, T1
Fukuda, K1
Huang, Z1
Liang, L1
Li, L1
Xu, M1
Li, X1
Sun, H1
He, S1
Lin, L1
Zhang, Y1
Song, Y1
Yang, M1
Luo, Y1
Loh, HH1
Law, PY1
Zheng, D1
Zheng, H1
Imajo, Y1
Komasawa, N1
Kusaka, Y1
Kido, H1
Minami, T1
Toki, K1
Yokose, M1
Miyashita, T1
Sato, H1
Fujimoto, H1
Yamamoto, S1
Goto, T1
Yao, J1
Ma, C1
Gao, W1
Liang, J1
Liu, C1
Yang, H1
Yan, Q1
Wen, Q1
Oztürk, T1
Karadibak, K1
Catal, D1
Cakan, A1
Tugsavul, F1
Cirak, K1
Yamamoto, Y1
Watanabe, S1
Kano, T1
Jiang, Z1
Dai, JQ1
Shi, C1
Zeng, WS1
Jiang, RC1
Tu, WF1
Sitte, T1
Shibuya, K1
Ishiyama, T1
Ichikawa, M1
Oguchi, T1
Matsukawa, T1
Gika, M1
Eguchi, K1
Inoue, Y1
Izawa, N1
Takeuchi, K1
Nakayama, M1
Tajitsu, T1
Matsuura, S1
Kawagoe, K1
Shibahara, H1
Ando, A1
Suzuki, S1
Uematsu, N1
Nishimura, D1
Füessl, HS1
Stiefelhagen, P1
Juba, KM1
Wahler, RG1
Daron, SM1
Takakuwa, O1
Oguri, T1
Maeno, K1
Yokoyama, M1
Hijikata, H1
Uemura, T1
Ozasa, H1
Ohkubo, H1
Miyazaki, M1
Niimi, A1
Kokko, H1
Hall, PD1
Afrin, LB1
Shavit, Y1
Ben-Eliyahu, S2
Zeidel, A1
Beilin, B1
Tikuisis, R1
Miliauskas, P1
Zurauskas, A1
Cicenas, S1
Eidukevicius, R1
Jackevicius, A1
Schultheis, CP1
Yu, SY1
Sun, Y1
Wu, YL1
Qin, SK1
Xie, GR1
Liu, SJ1
Sui, GJ1
Zhang, HC1
Shinjo, T1
Okada, M1
Takane, H1
Nosaka, A1
Wakushima, H1
Hosokawa, K1
Ieiri, I1
Benitez-Rosario, MA1
Martin, AS1
Feria, M1
Lin, CS1
Lu, G1
Ruan, LY1
Gu, MN1
Kamiya, N1
Yasogawa, Y1
Nishi, Y1
Takahashi, Y1
Kondo, Y1
Hirai, T1
Sakurai, M1
Masumizu, K1
Onosato, W1
Koyama, T1
Yoshioka, M1
Mori, T1
Kobayashi, H1
Iwatani, K1
Yoshimoto, K1
Terasaki, H1
Nomori, H1
Franchi, S1
Panerai, AE1
Sacerdote, P1
Jooste, EH1
Chalifoux, T1
Broadman, LM1
Gauna, AA1
Kang, SK1
Triano, ML1
Swatko, ER1
Vanston, VJ1
Giomarelli, PP1
Biagioli, B1
Sani, G1
Penza, B1
Portenoy, RK1
Southam, MA1
Gupta, SK1
Lapin, J1
Layman, M1
Inturrisi, CE1
Foley, KM1
Sylvester, RK1
Levitt, R1
Steen, PD1
Lilley, LL1
Guanci, R1
Gordon, RL1
Fujiwara, C1
Hirose, Y1
Gamo, M1
Harigae, M1
Matsuo, K1
Page, GG1
Blakely, WP1
Stoukides, CA1
Stegman, M1
Dewachter, P1
Boileau, S1
Laxenaire, MC1
Hughes, SA1
Benumof, JL1
Domenegati, E1
Ciccone, R1
Reali, F1
Reposi, C1
De Amici, D1
Rissotti, M1
Zeller, K1

Clinical Trials (6)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effects of Anesthetic Technique on Natural Killer Cell Population and Cytotoxicity[NCT02669186]20 participants (Anticipated)Interventional2019-07-10Enrolling by invitation
A Prospective Descriptive Study of the Individualized Capnography of Both Lungs During Single Lung Ventilation With Double-lumen Tube[NCT04962581]30 participants (Actual)Observational2021-07-04Completed
Randomized Prospective Study Comparing Paravertebral Catheters, Single Shot Paravertebral Block, Thoracic Epidural, for Postoperative Analgesia Following Video-assisted Thoracoscopic Surgery[NCT03151434]Phase 3147 participants (Actual)Interventional2017-02-07Completed
Supplementary Epidural Analgesia in Video-Assisted Thoracic Surgery (VATS) - The SEAVATS Study[NCT02359175]Phase 4161 participants (Actual)Interventional2015-02-28Completed
Effects of Epidural Anesthesia-analgesia on Long-term Survival in Patients After Lung Cancer Surgery: A Randomized Controlled Trial[NCT02801409]400 participants (Actual)Interventional2015-05-25Completed
Impact of Perioperative Dexmedetomidine on Long-term Survival in Older Patients After Cancer Surgery: a Multicenter Randomized Trial[NCT06030804]4,532 participants (Anticipated)Interventional2023-09-12Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Average Nausea Scores Over 72 Hours

Nausea scores will be collected by a study team member post operatively up to 3 days per protocol. Nausea will be recorded as 0=none, 1=mild, 2=moderate, or 3=severe (NCT03151434)
Timeframe: Nausea scores will be documented at 1 hour post op, 24,48,and 72 hours after the surgery.The scores will then be averaged.

Interventionunits on a scale (Mean)
Group #10.27
Group #20.27
Group #30.29

Average Sedation Scores Over 72 Hours

Sedation scores will be documented by a study team member post operatively up to 3 days per protocol requirements. Determining if patient is 0=awake and alert, 1=quietly awake, 2=asleep and arousable, or 3=deep sleep. (NCT03151434)
Timeframe: Sedation scores will be documented at 1 hour post op, 24,48,and 72 hours after the sugery. The scores will then be averaged.

Interventionunits on a scale (Mean)
Group #10.38
Group #20.32
Group #30.22

Secondary Endpoint Includes Total Intravenous Opioid Consumption at 72 Hours

Opioid consumption will be collected by a study team member post operatively up to 3 days per protocol time requirements (NCT03151434)
Timeframe: Opioid consumption will be measured at 1 hour post op, 24,48, and 72 hours post op. The total amount will be recorded.

Interventionmiligram morphine equivalent (Median)
Group #157
Group #235
Group #321.3

Subjects Overall Satisfaction Scores

Subjects will be followed up at 24 hours post operatively by a study team member to document patient overall satisfaction scores. Score was recorded as 0=dissatisfied, 1=satisfied, 2=very satisfied. (NCT03151434)
Timeframe: post operatively at hour 24

Interventionunits on a scale (Mean)
Group #10.89
Group #20.95
Group #31.33

Subjects Overall Satisfaction Scores

Subjects will be followed up at 48 hours post operatively by a study team member to document patient overall satisfaction scores. Scores will be recorded as 0=dissatisfied, 1=satisfied, 2=very satisfied. (NCT03151434)
Timeframe: post operatively at hour 48

Interventionunits on a scale (Mean)
Group #11.19
Group #21.05
Group #31.32

The Primary Endpoint of This Study Will be VAS Pain Score at 24 Hours

"The VAS score will be taken with both rest and movement (knee flexion) and will be measured by a study team investigator using Visual Analog Scale (VAS). Using units on a scale of 1-10 for documentation with 10 being the worst pain and 0 being no pain" (NCT03151434)
Timeframe: Pain scores will be measured 24 hours after surgery.

Interventionunits on a scale (Median)
US Guided Single Shot Paravertebral Block4.0
US Guided Paravertebral Catheter4.5
Thoracic Epidural3.0

The Primary Endpoint of This Study Will be VAS Pain Score at 48 Hours

"The VAS scores will be taken with both rest and movement (knee flexion) and will be measured by a study team investigator using Visual Analog Scale (VAS). Usingunits on a scale scale of 1-10 for documentation with 10 being the worst pain and 0 being no pain" (NCT03151434)
Timeframe: Pain scores will be measured 48 hours after surgery.

Interventionunits on a scale (Median)
US Guided Single Shot Paravertebral Block3.0
US Guided Paravertebral Catheter4.0
Thoracic Epidural2.0

Reviews

2 reviews available for fentanyl and Cancer of Lung

ArticleYear
[Involuntary Movement of Bilateral Lower Limbs Caused by Epidural Anesthesia: A Case Report].
    Masui. The Japanese journal of anesthesiology, 2016, Volume: 65, Issue:6

    Topics: Amides; Anesthesia, Epidural; Droperidol; Drug Combinations; Dyskinesia, Drug-Induced; Dyskinesias;

2016
[Nasal application of fentanyl citrate as symptom control against breathlessness in palliative care--overview and case report].
    Wiener medizinische Wochenschrift (1946), 2009, Volume: 159, Issue:23-24

    Topics: Acute Disease; Administration, Cutaneous; Administration, Intranasal; Aged, 80 and over; Ambulatory

2009

Trials

4 trials available for fentanyl and Cancer of Lung

ArticleYear
[Comparison of TD-fentanyl with sustained-release morphine in the pain treatment of patients with lung cancer].
    Agri : Agri (Algoloji) Dernegi'nin Yayin organidir = The journal of the Turkish Society of Algology, 2008, Volume: 20, Issue:3

    Topics: Administration, Cutaneous; Analgesics, Opioid; Chronic Disease; Delayed-Action Preparations; Female;

2008
Influence of patient-controlled i.v. analgesia with opioids on supraventricular arrhythmias after pulmonary resection.
    British journal of anaesthesia, 2009, Volume: 103, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opio

2009
[Patient-controlled intravenous analgesia with sufentanil and fentanyl after thoracotomy: a comparative study].
    Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2006, Volume: 26, Issue:2

    Topics: Adult; Analgesia, Patient-Controlled; Esophageal Neoplasms; Female; Fentanyl; Humans; Infusions, Int

2006
The efficacy of epidural analgesia after video-assisted thoracoscopic surgery: a randomized control study.
    Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia, 2006, Volume: 12, Issue:5

    Topics: Analgesia, Epidural; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Catheterization; Fentanyl;

2006
The efficacy of epidural analgesia after video-assisted thoracoscopic surgery: a randomized control study.
    Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia, 2006, Volume: 12, Issue:5

    Topics: Analgesia, Epidural; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Catheterization; Fentanyl;

2006
The efficacy of epidural analgesia after video-assisted thoracoscopic surgery: a randomized control study.
    Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia, 2006, Volume: 12, Issue:5

    Topics: Analgesia, Epidural; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Catheterization; Fentanyl;

2006
The efficacy of epidural analgesia after video-assisted thoracoscopic surgery: a randomized control study.
    Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia, 2006, Volume: 12, Issue:5

    Topics: Analgesia, Epidural; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Catheterization; Fentanyl;

2006

Other Studies

49 other studies available for fentanyl and Cancer of Lung

ArticleYear
Combined procedure with radial probe and convex probe endobronchial ultrasound.
    Thoracic cancer, 2022, Volume: 13, Issue:20

    Topics: Bronchoscopy; Endosonography; Fentanyl; Humans; Lung Neoplasms; Midazolam

2022
Postoperative pain and quality of life after lung cancer surgery: a prospective observational study.
    Annals of palliative medicine, 2023, Volume: 12, Issue:2

    Topics: Fentanyl; Humans; Lung Neoplasms; Pain Threshold; Pain, Postoperative; Quality of Life

2023
Fentanyl stimulates tumor angiogenesis via activating multiple pro-angiogenic signaling pathways.
    Biochemical and biophysical research communications, 2020, 11-05, Volume: 532, Issue:2

    Topics: Analgesics, Opioid; Cell Line, Tumor; Cell Movement; Cell Survival; Cells, Cultured; Endothelial Cel

2020
Sedation with fentanyl and midazolam without oropharyngeal anesthesia compared with sedation with pethidine and midazolam with oropharyngeal anesthesia in ultrathin bronchoscopy for peripheral lung lesions.
    Respiratory investigation, 2021, Volume: 59, Issue:2

    Topics: Adult; Anesthesia; Biopsy; Bronchoscopy; Conscious Sedation; Female; Fentanyl; Hemodynamics; Humans;

2021
Bronchoscopic diagnosis of peripheral pulmonary lung cancer employing sedation with fentanyl and midazolam.
    Respiratory investigation, 2017, Volume: 55, Issue:5

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Biopsy; Bronchoscopy; Carcinoma, Squamous Cell; Conscious S

2017
Deep sedation versus minimal sedation during endobronchial ultrasound transbronchial needle aspiration.
    Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace, 2018, 10-03, Volume: 88, Issue:3

    Topics: Adenocarcinoma; Adjuvants, Anesthesia; Adult; Aged; Aged, 80 and over; Anesthetics, Intravenous; Ant

2018
Correlation of P2RX7 gene rs1718125 polymorphism with postoperative fentanyl analgesia in patients with lung cancer.
    Medicine, 2019, Volume: 98, Issue:7

    Topics: Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Asian People; China; Female; Fentanyl; Geno

2019
Effects of surgery, general anesthesia, and perioperative epidural analgesia on the immune function of patients with non-small cell lung cancer.
    Journal of clinical anesthesia, 2013, Volume: 25, Issue:4

    Topics: Aged; Analgesia, Epidural; Analgesics, Opioid; Anesthesia, General; Carcinoma, Non-Small-Cell Lung;

2013
Effects of postoperative epidural analgesia on recurrence-free and overall survival in patients with nonsmall cell lung cancer.
    Journal of clinical anesthesia, 2014, Volume: 26, Issue:1

    Topics: Age Factors; Aged; Amides; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; A

2014
A retrospective analysis of the effect of intraoperative opioid dose on cancer recurrence after non-small cell lung cancer resection.
    Cancer medicine, 2014, Volume: 3, Issue:4

    Topics: Analgesics, Opioid; Carcinoma, Non-Small-Cell Lung; Disease-Free Survival; Dose-Response Relationshi

2014
[Evaluation of postoperative pain intensity related to post-thoracotomy pain syndrome occurring after video-assisted thoracic surgery lobectomy for lung cancer].
    Masui. The Japanese journal of anesthesiology, 2014, Volume: 63, Issue:4

    Topics: Aged; Amides; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics; Anti-Inflammatory Agen

2014
Endobronchial ultrasound-guided transbronchial needle aspiration: patient satisfaction under light conscious sedation.
    Respiration; international review of thoracic diseases, 2014, Volume: 88, Issue:3

    Topics: Anesthetics, Intravenous; Bronchoscopy; Carcinoma; Conscious Sedation; Endoscopic Ultrasound-Guided

2014
Can fentanyl transdermal patches prevent the cutaneous hyperpigmentation related to radiotherapy in patients with cancer?
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2016, Volume: 22, Issue:2

    Topics: Analgesics, Opioid; Carcinoma, Non-Small-Cell Lung; Fentanyl; Humans; Hyperpigmentation; Lung Neopla

2016
[Postoperative Pain after Hybrid Video-assisted Thoracic Surgery].
    Masui. The Japanese journal of anesthesiology, 2015, Volume: 64, Issue:12

    Topics: Aged; Analgesia; Female; Fentanyl; Humans; Lung Neoplasms; Male; Middle Aged; Nerve Block; Pain Mana

2015
Opioid doses required for pain management in lung cancer patients with different cholesterol levels: negative correlation between opioid doses and cholesterol levels.
    Lipids in health and disease, 2016, Mar-08, Volume: 15

    Topics: Analgesics, Opioid; Cholesterol; Female; Fentanyl; Humans; Lung Neoplasms; Male; Morphine; Oxycodone

2016
[Anesthetic Management for Lobectomy in a Patient with Pulmonary Arterial Hypertension].
    Masui. The Japanese journal of anesthesiology, 2016, Volume: 65, Issue:2

    Topics: Aged; Anesthesia; Dexmedetomidine; Female; Fentanyl; Humans; Hypertension, Pulmonary; Lung Neoplasms

2016
Fentanyl induces autophagy via activation of the ROS/MAPK pathway and reduces the sensitivity of cisplatin in lung cancer cells.
    Oncology reports, 2016, Volume: 36, Issue:6

    Topics: A549 Cells; Antineoplastic Agents; Autophagy; Cell Survival; Cisplatin; Drug Resistance, Neoplasm; F

2016
Gradient of bronchial end-tidal CO2 during two-lung ventilation in lateral decubitus position is predictive of oxygenation disorder during subsequent one-lung ventilation.
    Journal of anesthesia, 2009, Volume: 23, Issue:2

    Topics: Aged; Anesthesia, Intravenous; Anesthetics, Intravenous; Blood Gas Analysis; Carbon Dioxide; Female;

2009
[Mobitz type II block during one-lung ventilation].
    Masui. The Japanese journal of anesthesiology, 2010, Volume: 59, Issue:3

    Topics: Aged; Anesthesia, Epidural; Anesthesia, General; Atrioventricular Block; Fentanyl; Humans; Intraoper

2010
[Successful management of a patient with pain and dyspnea from bone metastasis and lymphangitis carcinomatosa after surgery for non-small cell lung cancer (NSCLC) in whom optimal dosages of transdermal fentanyl were determined by titration with fentanyl i
    Gan to kagaku ryoho. Cancer & chemotherapy, 2010, Volume: 37, Issue:3

    Topics: Administration, Cutaneous; Bone Neoplasms; Carcinoma, Non-Small-Cell Lung; Dyspnea; Female; Fentanyl

2010
[Home hospice care for the lung cancer patients].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2009, Volume: 36 Suppl 1

    Topics: Analgesics, Opioid; Dyspnea; Fentanyl; Home Care Services; Hospice Care; Humans; Lung Neoplasms; Mor

2009
[Oxycodone and pregabalin using transdermal fentanyl patch provided relief of symptoms for postherpetic neuropathic pain in a patient with non-small cell lung cancer].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2011, Volume: 38, Issue:10

    Topics: Aged; Analgesics, Opioid; Carcinoma, Non-Small-Cell Lung; Fentanyl; gamma-Aminobutyric Acid; Humans;

2011
[Breakthrough pain in a patient with bronchial carcinoma. Oral morphine hardly possible - what can help?].
    MMW Fortschritte der Medizin, 2012, Jun-11, Volume: 154, Issue:11

    Topics: Administration, Cutaneous; Administration, Oral; Analgesics, Opioid; Breakthrough Pain; Carcinoma, B

2012
Morphine and hydromorphone-induced hyperalgesia in a hospice patient.
    Journal of palliative medicine, 2013, Volume: 16, Issue:7

    Topics: Adult; Analgesics, Opioid; Carcinoma, Non-Small-Cell Lung; Delayed-Action Preparations; Female; Fent

2013
Analgesic effect of switching from oral opioids to a once-a-day fentanyl citrate transdermal patch in patients with lung cancer.
    The American journal of hospice & palliative care, 2013, Volume: 30, Issue:7

    Topics: Administration, Cutaneous; Analgesics, Opioid; Citric Acid; Fentanyl; Humans; Lung Neoplasms; Neopla

2013
Fentanyl-associated syndrome of inappropriate antidiuretic hormone secretion.
    Pharmacotherapy, 2002, Volume: 22, Issue:9

    Topics: Administration, Cutaneous; Adult; Analgesics, Opioid; Fatal Outcome; Female; Fentanyl; Humans; Inapp

2002
Effects of fentanyl on natural killer cell activity and on resistance to tumor metastasis in rats. Dose and timing study.
    Neuroimmunomodulation, 2004, Volume: 11, Issue:4

    Topics: Adenocarcinoma; Analgesics, Opioid; Animals; Cell Line, Tumor; Disease Models, Animal; Dose-Response

2004
[Hypotensive epidural anesthesia in thoracic surgery].
    Medicina (Kaunas, Lithuania), 2004, Volume: 40, Issue:12

    Topics: Adult; Aged; Analgesics, Opioid; Anesthesia, Epidural; Anesthesia, General; Anesthetics, Local; Bloo

2004
Nebulized fentanyl provides subjective improvements for patients with dyspnea.
    Oncology nursing forum, 2005, Volume: 32, Issue:1

    Topics: Administration, Inhalation; Dyspnea; Fentanyl; Humans; Lung Neoplasms; Narcotics; Nebulizers and Vap

2005
[Transdermal fentanyl for the management of cancer pain: a survey of 4492 patients].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 2005, Volume: 27, Issue:6

    Topics: Administration, Cutaneous; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Child; Ch

2005
[The opioid combination of transdermal fentanyl and sustained release morphine for refractory cancer pain--a case report].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2005, Volume: 32, Issue:12

    Topics: Administration, Cutaneous; Adult; Analgesics, Opioid; Delayed-Action Preparations; Drug Therapy, Com

2005
Rifampin reduces the analgesic effect of transdermal fentanyl.
    The Annals of pharmacotherapy, 2005, Volume: 39, Issue:12

    Topics: Adenocarcinoma; Administration, Cutaneous; Aged; Analgesics, Opioid; Antibiotics, Antitubercular; Dr

2005
Oral transmucosal fentanyl citrate in the management of dyspnea crises in cancer patients.
    Journal of pain and symptom management, 2005, Volume: 30, Issue:5

    Topics: Administration, Oral; Aged; Analgesics, Opioid; Dyspnea; Female; Fentanyl; Humans; Lung Neoplasms; M

2005
[A case of long-term, high-dose transdermal fentanyl application for lung cancer pain].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2006, Volume: 33, Issue:3

    Topics: Administration, Cutaneous; Analgesics, Opioid; Bone Neoplasms; Female; Fentanyl; Humans; Lung Neopla

2006
Buprenorphine ameliorates the effect of surgery on hypothalamus-pituitary-adrenal axis, natural killer cell activity and metastatic colonization in rats in comparison with morphine or fentanyl treatment.
    Brain, behavior, and immunity, 2007, Volume: 21, Issue:6

    Topics: Analgesics, Opioid; Analysis of Variance; Animals; Breast Neoplasms; Buprenorphine; Corticosterone;

2007
A perioperative strategy for the placement of a thoracic epidural catheter in a pediatric patient on high-dose enoxaprin.
    Paediatric anaesthesia, 2007, Volume: 17, Issue:9

    Topics: Adult; Anesthesia, Epidural; Anesthetics, Intravenous; Anticoagulants; Enoxaparin; Fentanyl; Hematom

2007
Oral transmucosal fentanyl citrate for dyspnea in terminally ill patients: an observational case series.
    Journal of palliative medicine, 2008, Volume: 11, Issue:4

    Topics: Aged; Aged, 80 and over; Analgesics, Opioid; Dyspnea; Female; Fentanyl; Heart Failure; Humans; Lung

2008
[Anesthesia problems in thoracic and lung surgery; the use of althesin as an alternative solution].
    Minerva anestesiologica, 1980, Volume: 46, Issue:2

    Topics: Adult; Alfaxalone Alfadolone Mixture; Anesthesia; Droperidol; Fentanyl; Hemodynamics; Humans; Lung N

1980
Transdermal fentanyl for cancer pain. Repeated dose pharmacokinetics.
    Anesthesiology, 1993, Volume: 78, Issue:1

    Topics: Administration, Cutaneous; Adult; Aged; Breast Neoplasms; Colonic Neoplasms; Female; Fentanyl; Human

1993
Opioid-induced muscle activity: implications for managing chronic pain.
    The Annals of pharmacotherapy, 1995, Volume: 29, Issue:11

    Topics: Adenocarcinoma, Mucinous; Aged; Analgesics, Opioid; Chronic Disease; Fentanyl; Humans; Hyperkinesis;

1995
Using high-dose fentanyl patches.
    The American journal of nursing, 1996, Volume: 96, Issue:7

    Topics: Administration, Cutaneous; Analgesics, Opioid; Chronic Disease; Fentanyl; Humans; Lung Neoplasms; Ma

1996
Prolonged central intravenous ketorolac continuous infusion in a cancer patient with intractable bone pain.
    The Annals of pharmacotherapy, 1998, Volume: 32, Issue:2

    Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Bone Neoplasms; Carcinoma, Non-Small-Cell Lung; Cathet

1998
[Anesthetic management for placement of tracheobronchial stents in patients with airway stenosis].
    Masui. The Japanese journal of anesthesiology, 2000, Volume: 49, Issue:5

    Topics: Adult; Aged; Anesthesia, Intravenous; Esophageal Neoplasms; Female; Fentanyl; Humans; Lung Neoplasms

2000
Evidence that postoperative pain is a mediator of the tumor-promoting effects of surgery in rats.
    Pain, 2001, Feb-01, Volume: 90, Issue:1-2

    Topics: Adenocarcinoma; Analgesics, Opioid; Anesthetics, Local; Animals; Antiviral Agents; Bupivacaine; Expl

2001
Evidence that postoperative pain is a mediator of the tumor-promoting effects of surgery in rats.
    Pain, 2001, Feb-01, Volume: 90, Issue:1-2

    Topics: Adenocarcinoma; Analgesics, Opioid; Anesthetics, Local; Animals; Antiviral Agents; Bupivacaine; Expl

2001
Evidence that postoperative pain is a mediator of the tumor-promoting effects of surgery in rats.
    Pain, 2001, Feb-01, Volume: 90, Issue:1-2

    Topics: Adenocarcinoma; Analgesics, Opioid; Anesthetics, Local; Animals; Antiviral Agents; Bupivacaine; Expl

2001
Evidence that postoperative pain is a mediator of the tumor-promoting effects of surgery in rats.
    Pain, 2001, Feb-01, Volume: 90, Issue:1-2

    Topics: Adenocarcinoma; Analgesics, Opioid; Anesthetics, Local; Animals; Antiviral Agents; Bupivacaine; Expl

2001
Diffuse rash associated with transdermal fentanyl.
    Clinical pharmacy, 1992, Volume: 11, Issue:3

    Topics: Administration, Cutaneous; Carcinoma; Drug Eruptions; Female; Fentanyl; Humans; Lung Neoplasms; Midd

1992
[The reduction of anesthetic risk by high frequency jet ventilation during endobronchial cryotherapy].
    Cahiers d'anesthesiologie, 1991, Volume: 39, Issue:6

    Topics: Adult; Aged; Anesthesia, Intravenous; Cryosurgery; Fentanyl; High-Frequency Jet Ventilation; Humans;

1991
Operative lung continuous positive airway pressure to minimize FIO2 during one-lung ventilation.
    Anesthesia and analgesia, 1990, Volume: 71, Issue:1

    Topics: Adult; Anesthesia, Inhalation; Fentanyl; Humans; Isoflurane; Lung; Lung Neoplasms; Male; Midazolam;

1990
[Anesthesiologic management for lower pulmonary lobectomy intervention in patients with heart transplant. A clinical case].
    Minerva anestesiologica, 1989, Volume: 55, Issue:11

    Topics: Adenocarcinoma; Anesthesia, General; Fentanyl; Heart Transplantation; Humans; Lung Neoplasms; Male;

1989
[Anesthesia in chronic patients].
    Bibliotheca tuberculosea, 1969, Volume: 25

    Topics: Adult; Aged; Anesthesia; Anesthetics; Anti-Bacterial Agents; Asthma; Benperidol; Chronic Disease; Fe

1969