fentanyl has been researched along with Cancer of Head in 16 studies
Fentanyl: A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078)
fentanyl : A monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of N-phenyl-1-(2-phenylethyl)piperidin-4-amine with propanoic acid.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This is the first study to show noninferiority of methadone compared to fentanyl at 1 and 3 weeks in the treatment of radiation-induced nociceptive pain in patients with head and neck cancer." | 9.27 | Methadone versus Fentanyl in Patients with Radiation-Induced Nociceptive Pain with Head and Neck Cancer: A Randomized Controlled Noninferiority Trial. ( Geurts, JW; Haumann, J; Hoebers, FJP; Joosten, EA; Kremer, B; van den Beuken-van Everdingen, MHJ; van Kuijk, SMJ, 2018) |
| "This study evaluated the efficacy and safety of transdermal fentanyl in the outpatient treatment of head and neck cancer patients with pain caused by radiotherapy." | 9.14 | Transdermal fentanyl for pain caused by radiotherapy in head and neck cancer patients treated in an outpatient setting: a multicenter trial in Taiwan. ( Chang, JT; Chen, YJ; Lee, MS; Lin, CY; Lin, JC; Wang, HM, 2010) |
| "A retrospective analysis was conduct on HNC patients during RT ± ChT that received fentanyl pectin na sal spray (FPNS) for incidental BTP due to painful mucositis 13 min before the main meals." | 7.85 | Fentanyl pectin nasal spray for painful mucositis in head and neck cancers during intensity-modulated radiation therapy with or without chemotherapy. ( Albanese, S; Alongi, F; Fersino, S; Fiorentino, A; Giaj-Levra, N; Gori, S; Mazzola, R; Ricchetti, F; Tebano, U, 2017) |
| "This is the first study to show noninferiority of methadone compared to fentanyl at 1 and 3 weeks in the treatment of radiation-induced nociceptive pain in patients with head and neck cancer." | 5.27 | Methadone versus Fentanyl in Patients with Radiation-Induced Nociceptive Pain with Head and Neck Cancer: A Randomized Controlled Noninferiority Trial. ( Geurts, JW; Haumann, J; Hoebers, FJP; Joosten, EA; Kremer, B; van den Beuken-van Everdingen, MHJ; van Kuijk, SMJ, 2018) |
| "This study evaluated the efficacy and safety of transdermal fentanyl in the outpatient treatment of head and neck cancer patients with pain caused by radiotherapy." | 5.14 | Transdermal fentanyl for pain caused by radiotherapy in head and neck cancer patients treated in an outpatient setting: a multicenter trial in Taiwan. ( Chang, JT; Chen, YJ; Lee, MS; Lin, CY; Lin, JC; Wang, HM, 2010) |
| "A retrospective analysis was conduct on HNC patients during RT ± ChT that received fentanyl pectin na sal spray (FPNS) for incidental BTP due to painful mucositis 13 min before the main meals." | 3.85 | Fentanyl pectin nasal spray for painful mucositis in head and neck cancers during intensity-modulated radiation therapy with or without chemotherapy. ( Albanese, S; Alongi, F; Fersino, S; Fiorentino, A; Giaj-Levra, N; Gori, S; Mazzola, R; Ricchetti, F; Tebano, U, 2017) |
| "Cancer pain is still inadequately treated in up to 60% of cancer patients." | 2.82 | Methadone is superior to fentanyl in treating neuropathic pain in patients with head-and-neck cancer. ( Geurts, JW; Haumann, J; Joosten, EA; Kremer, B; van den Beuken-van Everdingen, MH; van Kuijk, SM, 2016) |
| "Head and neck cancers (HNC) represent 5% of all malignancies worldwide with about 180,000 cancer deaths per year." | 2.66 | Is pain part of a systemic syndrome in head and neck cancer? ( Argenone, A; Bossi, P; Depenni, R; Ghiani, M, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (12.50) | 18.2507 |
| 2000's | 3 (18.75) | 29.6817 |
| 2010's | 9 (56.25) | 24.3611 |
| 2020's | 2 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Mercadante, S | 3 |
| Bossi, P | 2 |
| Ghiani, M | 1 |
| Argenone, A | 1 |
| Depenni, R | 1 |
| Haumann, J | 4 |
| van Kuijk, SMJ | 2 |
| Geurts, JW | 3 |
| Hoebers, FJP | 1 |
| Kremer, B | 3 |
| Joosten, EA | 4 |
| van den Beuken-van Everdingen, MHJ | 2 |
| Masedu, F | 1 |
| Valenti, M | 1 |
| Aielli, F | 1 |
| Locati, L | 1 |
| Bergamini, C | 1 |
| Mirabile, A | 1 |
| Granata, R | 1 |
| Imbimbo, M | 1 |
| Resteghini, C | 1 |
| Licitra, L | 1 |
| van Kuijk, SM | 2 |
| van den Beuken-van Everdingen, MH | 2 |
| Ruan, X | 1 |
| Luo, JJ | 1 |
| Kaye, AD | 1 |
| Mazzola, R | 1 |
| Ricchetti, F | 1 |
| Fiorentino, A | 1 |
| Giaj-Levra, N | 1 |
| Fersino, S | 1 |
| Tebano, U | 1 |
| Albanese, S | 1 |
| Gori, S | 1 |
| Alongi, F | 1 |
| Chang, JT | 1 |
| Lin, CY | 1 |
| Lin, JC | 1 |
| Lee, MS | 1 |
| Chen, YJ | 1 |
| Wang, HM | 1 |
| Villari, P | 1 |
| Ferrera, P | 1 |
| Macheta, A | 1 |
| Muszyński, T | 1 |
| Podziorny, H | 1 |
| Cebula, G | 1 |
| Andres, J | 1 |
| Shaiova, L | 1 |
| Lapin, J | 1 |
| Manco, LS | 1 |
| Shasha, D | 1 |
| Hu, K | 1 |
| Harrison, L | 1 |
| Portenoy, RK | 1 |
| Grond, S | 1 |
| Zech, D | 1 |
| Lehmann, KA | 1 |
| Radbruch, L | 1 |
| Breitenbach, H | 1 |
| Hertel, D | 1 |
| Nagase, K | 1 |
| Akamatsu, S | 1 |
| Ueda, N | 1 |
| Shimonaka, H | 1 |
| Dohi, S | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Methadone for 'Adenocarcinopathic' Pain Treatment: Methadone vs. Morphine Vanguard RCT[NCT05325164] | Phase 3 | 0 participants (Actual) | Interventional | 2022-09-30 | Withdrawn (stopped due to Trial not started; change in Sponsor and Principal Investigator, trial to be registered again by new Sponsor/Investigator if it is started.) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for fentanyl and Cancer of Head
| Article | Year |
|---|---|
Breakthrough cancer pain in the radiotherapy setting: a systematic and critical review.
Topics: Analgesics, Opioid; Breakthrough Pain; Cancer Pain; Fentanyl; Head and Neck Neoplasms; Humans; Neopl | 2023 |
Is pain part of a systemic syndrome in head and neck cancer?
Topics: Analgesics, Opioid; Breakthrough Pain; Cancer Pain; Depression; Exercise; Fatigue; Fentanyl; Head an | 2020 |
7 trials available for fentanyl and Cancer of Head
| Article | Year |
|---|---|
Methadone versus Fentanyl in Patients with Radiation-Induced Nociceptive Pain with Head and Neck Cancer: A Randomized Controlled Noninferiority Trial.
Topics: Adult; Aged; Analgesics, Opioid; Female; Fentanyl; Head and Neck Neoplasms; Humans; Male; Methadone; | 2018 |
Breakthrough pain in patients with head & neck cancer. A secondary analysis of IOPS MS study.
Topics: Administration, Intranasal; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Breakthr | 2019 |
Methadone is superior to fentanyl in treating neuropathic pain in patients with head-and-neck cancer.
Topics: Adult; Aged; Analgesics, Opioid; Cancer Pain; Female; Fentanyl; Head and Neck Neoplasms; Humans; Mal | 2016 |
Transdermal fentanyl for pain caused by radiotherapy in head and neck cancer patients treated in an outpatient setting: a multicenter trial in Taiwan.
Topics: Administration, Cutaneous; Adult; Aged; Analgesics, Opioid; Female; Fentanyl; Head and Neck Neoplasm | 2010 |
[Mivacurium--use for complications of facial-cranial surgery--personal experience].
Topics: Adolescent; Adult; Aged; Anesthesia, General; Facial Bones; Female; Fentanyl; Head and Neck Neoplasm | 2001 |
Tolerability and effects of two formulations of oral transmucosal fentanyl citrate (OTFC; ACTIQ) in patients with radiation-induced oral mucositis.
Topics: Administration, Oral; Adult; Aged; Analgesics, Opioid; Chemistry, Pharmaceutical; Cross-Over Studies | 2004 |
Transdermal fentanyl in the long-term treatment of cancer pain: a prospective study of 50 patients with advanced cancer of the gastrointestinal tract or the head and neck region.
Topics: Administration, Cutaneous; Analgesics, Opioid; Female; Fentanyl; Gastrointestinal Neoplasms; Head an | 1997 |
7 other studies available for fentanyl and Cancer of Head
| Article | Year |
|---|---|
The Association between Patient Characteristics and Opioid Treatment Response in Neuropathic and Nociceptive Pain due to Cancer.
Topics: Aged; Analgesics, Opioid; Cancer Pain; Female; Fentanyl; Head and Neck Neoplasms; Humans; Male; Midd | 2019 |
Fentanyl pectin nasal spray as treatment for incident predictable breakthrough pain (BTP) in oral mucositis induced by chemoradiotherapy in head and neck cancer.
Topics: Administration, Inhalation; Adult; Aged; Analgesics, Opioid; Breakthrough Pain; Combined Modality Th | 2014 |
Letter response: Methadone is superior to fentanyl in treating neuropathic pain in patients with head-and-neck cancer.
Topics: Analgesics, Opioid; Fentanyl; Head and Neck Neoplasms; Humans; Methadone; Neuralgia; Pain; Pain Meas | 2016 |
Methadone is superior to fentanyl in treating neuropathic pain in patients with head-and-neck cancer.
Topics: Analgesics, Opioid; Fentanyl; Head and Neck Neoplasms; Humans; Methadone; Neoplasms; Neuralgia; Pain | 2016 |
Fentanyl pectin nasal spray for painful mucositis in head and neck cancers during intensity-modulated radiation therapy with or without chemotherapy.
Topics: Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Antineoplastic Agents; Breakthrough Pain; Cispla | 2017 |
Itraconazole-fentanyl interaction in a cancer patient.
Topics: Aged; Analgesics, Opioid; Antifungal Agents; Drug Interactions; Fentanyl; Head and Neck Neoplasms; H | 2002 |
[Difficult tracheal intubation with von Recklinghausen disease].
Topics: Adolescent; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Combined; Anesthetics, Inh | 1998 |