fentanyl has been researched along with Cancer of Cervix in 8 studies
Fentanyl: A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078)
fentanyl : A monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of N-phenyl-1-(2-phenylethyl)piperidin-4-amine with propanoic acid.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To report a case of high transdermal fentanyl dosage requirements in a patient with chronic cancer pain." | 7.68 | High transdermal fentanyl requirements in a patient with chronic cancer pain. ( Lehr, VT; Renaud, EA, 1993) |
| "To report a case of high transdermal fentanyl dosage requirements in a patient with chronic cancer pain." | 3.68 | High transdermal fentanyl requirements in a patient with chronic cancer pain. ( Lehr, VT; Renaud, EA, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (25.00) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Rezniczek, GA | 1 |
| Hecken, JM | 1 |
| Rehman, S | 1 |
| Dogan, A | 1 |
| Tempfer, CB | 1 |
| Hilal, Z | 1 |
| Thanthong, S | 1 |
| Rojthamarat, S | 1 |
| Worasawate, W | 1 |
| Vichitvejpaisal, P | 1 |
| Nantajit, D | 1 |
| Ieumwananontachai, N | 1 |
| Wang, X | 1 |
| Liu, W | 1 |
| Xu, Z | 1 |
| Wang, F | 1 |
| Zhang, C | 1 |
| Wang, B | 1 |
| Wang, K | 1 |
| Yu, J | 1 |
| George, R | 1 |
| Poonnoose, P | 1 |
| Isaiah, R | 1 |
| Chari, P | 1 |
| Ghai, B | 1 |
| Lehr, VT | 1 |
| Renaud, EA | 1 |
| Guliaev, GV | 1 |
| Iakobidze, MA | 1 |
| Mistakopulo, NF | 1 |
| Rylov, VV | 1 |
| Dudko, AN | 1 |
| Tasker, RR | 1 |
| Organ, LW | 1 |
| Smith, KC | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Large Loop Excision of the Transformation Zone (LLETZ) With Versus Without Intraoperative Application of Lugol's Iodine in Women With Cervical Dysplasia: a Prospective Randomized Trial[NCT05132114] | 216 participants (Anticipated) | Interventional | 2022-01-17 | Recruiting | |||
| Large Loop Excision of the Transformatione Zone Under General Versus Local Anesthesia: a Randomized Trial.[NCT03494686] | 229 participants (Actual) | Interventional | 2018-04-03 | Completed | |||
| Comparison of Meperidine and Fentanyl on Pain Scale and Quality of Life in Cervical Cancer Patients Receiving Brachytherapy: A Double-blind, Randomized Controlled Trial[NCT02684942] | Phase 4 | 40 participants (Actual) | Interventional | 2012-10-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Sum of fentanyl dose when finish each fraction of brachytherapy (NCT02684942)
Timeframe: after complete treatment.
| Intervention | ug. (Mean) |
|---|---|
| Fentanyl | 100.18 |
Sum of meperidine dose when finish each fraction of brachytherapy (NCT02684942)
Timeframe: after complete treatment.
| Intervention | mg. (Mean) |
|---|---|
| Meperidine | 50.13 |
Size of ovoids that a pair part of brachytherapy applicator insert in vagina trough cervix. (NCT02684942)
Timeframe: after complete applicator insertion.
| Intervention | Centimeter (Median) |
|---|---|
| Meperidine | 2 |
| Fentanyl | 2 |
Size of tumor at cervix measured by the doctor before insert applicator. (NCT02684942)
Timeframe: Before insert applicator in each fraction of brachytherapy.
| Intervention | CM. (Mean) |
|---|---|
| Meperidine | 2.23 |
| Fentanyl | 2.21 |
Perceived pain score according to standard 10-cm visual analog scales (VAS) was assessed before injection of medicine for every 15 minutes up to 120 minutes.The minimum and maximum scores were 0, 10. Score 0 means no pain, 1-3 mild pain, 4-6 moderate pain, 7-9 severe pain and 10 worst pain. (NCT02684942)
Timeframe: From date of the first fraction until date of the last fraction of brachytherapy, once a week for four weeks
| Intervention | units on a scale (Mean) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| baseline | 0 minute | 15 minute | 30 minute | 45 minute | 60 minute | 75 minute | 90 minute | 105 minute | 120 minute | |
| Fentanyl | 0.14 | 0.40 | 0.65 | 1.24 | 1.70 | 0.81 | 0.53 | 0.13 | 0.13 | 0.13 |
| Meperidine | 0.04 | 0.49 | 0.59 | 1.05 | 1.33 | 0.61 | 0.49 | 0.24 | 0.24 | 0.24 |
Perceived Quality of life (EQ-5D) was assessed before the first brachytherpy and immediately after completion of each of the 4 brachytherapy fractions. The EQ-5D have 5 dimensions: mobility, self-care, usual activities, topics each content 3 responses: no problems, some problems, extreme problems. (NCT02684942)
Timeframe: From date of the first fraction of brachytherapy until date of the last fraction of brachytherapy,once a week for 4 weeks
| Intervention | participants (Number) | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| No problems in mobility | Some problems in mobility | Severe problems in mobility | No problem in self-care | Some problem in self-care | Severe problem in self-care | No problem in usual activities | Some problem in usual activities | Severe problem in usual activities | No problem in pain/discomfort | Some problem in pain/discomfort | Severe problem in pain/discomfort | No problem in anxiety/depression | Some problem in anxiety/depression | Severe problem in anxiety/depression | |
| Fentanyl | 58 | 18 | 1 | 69 | 6 | 2 | 53 | 21 | 3 | 23 | 53 | 1 | 42 | 33 | 2 |
| Meperidine | 62 | 16 | 1 | 68 | 11 | 0 | 55 | 22 | 2 | 27 | 49 | 3 | 46 | 32 | 1 |
4 trials available for fentanyl and Cancer of Cervix
| Article | Year |
|---|---|
Syringe or mask? Loop electrosurgical excision procedure under local or general anesthesia: a randomized trial.
Topics: Adenocarcinoma in Situ; Adult; Anesthesia, General; Anesthesia, Local; Anesthetics, Inhalation; Anes | 2020 |
Syringe or mask? Loop electrosurgical excision procedure under local or general anesthesia: a randomized trial.
Topics: Adenocarcinoma in Situ; Adult; Anesthesia, General; Anesthesia, Local; Anesthetics, Inhalation; Anes | 2020 |
Syringe or mask? Loop electrosurgical excision procedure under local or general anesthesia: a randomized trial.
Topics: Adenocarcinoma in Situ; Adult; Anesthesia, General; Anesthesia, Local; Anesthetics, Inhalation; Anes | 2020 |
Syringe or mask? Loop electrosurgical excision procedure under local or general anesthesia: a randomized trial.
Topics: Adenocarcinoma in Situ; Adult; Anesthesia, General; Anesthesia, Local; Anesthetics, Inhalation; Anes | 2020 |
Comparison of efficacy of meperidine and fentanyl in terms of pain management and quality of life in patients with cervical cancer receiving intracavitary brachytherapy: a double-blind, randomized controlled trial.
Topics: Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Brachytherapy; Double-Blind Method; Female; Fent | 2017 |
Effect of Dexmedetomidine Alone for Intravenous Patient-Controlled Analgesia After Gynecological Laparoscopic Surgery: A Consort-Prospective, Randomized, Controlled Trial.
Topics: Administration, Intravenous; Adult; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analges | 2016 |
Comparison of butorphanol and thiopentone vs fentanyl and thiopentone for laryngeal mask airway insertion.
Topics: Adjuvants, Anesthesia; Analgesics, Opioid; Anesthesia, Intravenous; Anesthetics, Combined; Anestheti | 2006 |
4 other studies available for fentanyl and Cancer of Cervix
| Article | Year |
|---|---|
Dercum's disease (Adiposis dolorosa): delayed diagnosis in a patient with cervical cancer.
Topics: Adiposis Dolorosa; Adult; Amitriptyline; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Antide | 2004 |
High transdermal fentanyl requirements in a patient with chronic cancer pain.
Topics: Administration, Cutaneous; Adult; Carcinoma, Squamous Cell; Chronic Disease; Female; Fentanyl; Human | 1993 |
[Changes in the function of the kidney and water-salt metabolism in patients with extensive extirpation of the uterus with its appendages under neuroleptoanesthesia].
Topics: Adult; Aminophylline; Droperidol; Female; Fentanyl; Humans; Hysterectomy; Kidney; Middle Aged; Neuro | 1976 |
Physiological guidelines for the localization of lesions by percutaneous cordotomy.
Topics: Anesthesia, Local; Cordotomy; Electric Stimulation; Female; Fentanyl; Humans; Pain, Intractable; Rec | 1974 |