Page last updated: 2024-10-27

fentanyl and Cachexia

fentanyl has been researched along with Cachexia in 6 studies

Fentanyl: A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078)
fentanyl : A monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of N-phenyl-1-(2-phenylethyl)piperidin-4-amine with propanoic acid.

Cachexia: General ill health, malnutrition, and weight loss, usually associated with chronic disease.

Research Excerpts

ExcerptRelevanceReference
" The patient is a 50-year-old female with widely metastatic breast cancer who developed opioid toxicity when maintenance transdermal fentanyl patch therapy (100 μg patch applied every 72 h) was rotated to subcutaneous hydromorphone infusion to improve pain control."9.12Opioid rotation from transdermal fentanyl to continuous subcutaneous hydromorphone in a cachectic patient: A case report and review of the literature. ( Chua, D; Jackson, LD; Selby, D; Wortzman, R, 2021)
"It is recommended not to use transdermal fentanyl (Fe) patches (TFP) in cancer cachexia but TFP may be the only available option for pain."8.12Transdermal fentanyl to parenteral morphine route switch and drug rotation in refractory cancer cachexia. ( Alabdullateef, SH; Almashiakhi, M; Alsirafy, SA; Elyamany, AM; Hassan, AD, 2022)
"The objective of this study was to evaluate the influence of cancer cachexia on pain control in cancer patients receiving a transdermal fentanyl patch (FP) and to investigate whether dry skin was a factor related to cancer cachexia and uncontrolled pain."7.96Cancer Cachexia May Hinder Pain Control When Using Fentanyl Patch. ( Chiba, T; Kimura, S; Kudo, K; Tairabune, T; Takahashi, H; Ueda, H, 2020)
"Fentanyl is an opioid with high lipid solubility, suitable for intravenous, spinal, transmucosal and transdermal administration."6.74Transdermal fentanyl in cachectic cancer patients. ( Gergov, M; Haakana, S; Heiskanen, T; Kalso, E; Mätzke, S; Vuori, E, 2009)
"Fentanyl has a low molecular weight and is lipophilic making it suitable for transdermal administration."5.51Unusual case of transdermal fentanyl in cachexia. ( Harrison, S; Kay, S; Lam, D; Pickard, J, 2019)
" The patient is a 50-year-old female with widely metastatic breast cancer who developed opioid toxicity when maintenance transdermal fentanyl patch therapy (100 μg patch applied every 72 h) was rotated to subcutaneous hydromorphone infusion to improve pain control."5.12Opioid rotation from transdermal fentanyl to continuous subcutaneous hydromorphone in a cachectic patient: A case report and review of the literature. ( Chua, D; Jackson, LD; Selby, D; Wortzman, R, 2021)
"It is recommended not to use transdermal fentanyl (Fe) patches (TFP) in cancer cachexia but TFP may be the only available option for pain."4.12Transdermal fentanyl to parenteral morphine route switch and drug rotation in refractory cancer cachexia. ( Alabdullateef, SH; Almashiakhi, M; Alsirafy, SA; Elyamany, AM; Hassan, AD, 2022)
"The objective of this study was to evaluate the influence of cancer cachexia on pain control in cancer patients receiving a transdermal fentanyl patch (FP) and to investigate whether dry skin was a factor related to cancer cachexia and uncontrolled pain."3.96Cancer Cachexia May Hinder Pain Control When Using Fentanyl Patch. ( Chiba, T; Kimura, S; Kudo, K; Tairabune, T; Takahashi, H; Ueda, H, 2020)
"Fentanyl is an opioid with high lipid solubility, suitable for intravenous, spinal, transmucosal and transdermal administration."2.74Transdermal fentanyl in cachectic cancer patients. ( Gergov, M; Haakana, S; Heiskanen, T; Kalso, E; Mätzke, S; Vuori, E, 2009)
"Fentanyl has a low molecular weight and is lipophilic making it suitable for transdermal administration."1.51Unusual case of transdermal fentanyl in cachexia. ( Harrison, S; Kay, S; Lam, D; Pickard, J, 2019)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (33.33)29.6817
2010's1 (16.67)24.3611
2020's3 (50.00)2.80

Authors

AuthorsStudies
Alsirafy, SA1
Alabdullateef, SH1
Elyamany, AM1
Hassan, AD1
Almashiakhi, M1
Chiba, T1
Takahashi, H1
Tairabune, T1
Kimura, S1
Ueda, H1
Kudo, K1
Jackson, LD1
Wortzman, R1
Chua, D1
Selby, D1
Lam, D1
Kay, S1
Pickard, J1
Harrison, S1
Heiskanen, T1
Mätzke, S1
Haakana, S1
Gergov, M1
Vuori, E1
Kalso, E1
D'Olimpio, J1

Reviews

2 reviews available for fentanyl and Cachexia

ArticleYear
Opioid rotation from transdermal fentanyl to continuous subcutaneous hydromorphone in a cachectic patient: A case report and review of the literature.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2021, Volume: 27, Issue:1

    Topics: Administration, Cutaneous; Analgesics, Opioid; Cachexia; Canada; Female; Fentanyl; Humans; Hydromorp

2021
Contemporary drug therapy in palliative care: new directions.
    Cancer investigation, 2001, Volume: 19, Issue:4

    Topics: Adrenal Cortex Hormones; Analgesics; Anorexia; Antiemetics; Antitussive Agents; Cachexia; Cough; Dru

2001

Trials

1 trial available for fentanyl and Cachexia

ArticleYear
Transdermal fentanyl in cachectic cancer patients.
    Pain, 2009, Volume: 144, Issue:1-2

    Topics: Administration, Cutaneous; Adolescent; Adult; Aged; Analgesics, Opioid; Body Mass Index; Cachexia; C

2009

Other Studies

3 other studies available for fentanyl and Cachexia

ArticleYear
Transdermal fentanyl to parenteral morphine route switch and drug rotation in refractory cancer cachexia.
    BMJ supportive & palliative care, 2022, Volume: 12, Issue:e2

    Topics: Administration, Cutaneous; Analgesics, Opioid; Cachexia; Female; Fentanyl; Humans; Morphine; Neoplas

2022
Cancer Cachexia May Hinder Pain Control When Using Fentanyl Patch.
    Biological & pharmaceutical bulletin, 2020, Volume: 43, Issue:5

    Topics: Aged; Analgesics, Opioid; Cachexia; Cancer Pain; Female; Fentanyl; Humans; Male; Middle Aged; Morphi

2020
Unusual case of transdermal fentanyl in cachexia.
    BMJ supportive & palliative care, 2019, Volume: 9, Issue:4

    Topics: Analgesics, Opioid; Cachexia; Female; Fentanyl; Hospices; Humans; Middle Aged; Naloxone; Narcotic An

2019