fentanyl has been researched along with Brain Swelling in 7 studies
Fentanyl: A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078)
fentanyl : A monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of N-phenyl-1-(2-phenylethyl)piperidin-4-amine with propanoic acid.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In rabbits who had brain edema and intracranial hypertension induced by a combined cold lesion (over the left hemisphere) and a metabolic blocker (6-aminonicotinamide), the authors analyzed the response of multiple parameters following the administration of 6 mcg/kg/dose of fentanyl every 5 minutes for 1 hour (12 doses), combined with nitrous oxide anesthesia." | 7.67 | The effects of acute high dose fentanyl administration on experimental brain edema: analysis of intracranial pressure, systemic arterial pressure, central venous pressure and brain water content. ( James, HE; Moore, S; Tiznado, E, 1986) |
| "The study indicates that before as well as during hyperventilation, subdural ICP and AVDo2 are lower and CPP higher in propofol-anesthetized patients compared with patients anesthetized with isoflurane or sevoflurane." | 5.10 | Intracranial pressure and cerebral hemodynamic in patients with cerebral tumors: a randomized prospective study of patients subjected to craniotomy in propofol-fentanyl, isoflurane-fentanyl, or sevoflurane-fentanyl anesthesia. ( Cold, GE; Hauerberg, J; Holst, P; Landsfeldt, U; Mau, S; Olsen, KS; Petersen, CB; Petersen, KD, 2003) |
| "In rabbits who had brain edema and intracranial hypertension induced by a combined cold lesion (over the left hemisphere) and a metabolic blocker (6-aminonicotinamide), the authors analyzed the response of multiple parameters following the administration of 6 mcg/kg/dose of fentanyl every 5 minutes for 1 hour (12 doses), combined with nitrous oxide anesthesia." | 3.67 | The effects of acute high dose fentanyl administration on experimental brain edema: analysis of intracranial pressure, systemic arterial pressure, central venous pressure and brain water content. ( James, HE; Moore, S; Tiznado, E, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (28.57) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Jasne, AS | 1 |
| Alsherbini, KA | 1 |
| Smith, MS | 1 |
| Kuohn, LR | 1 |
| Pandhi, A | 1 |
| Vagal, A | 1 |
| Kanter, DS | 1 |
| Chen, CH | 1 |
| Mullen, AJ | 1 |
| Hofstede, D | 1 |
| Rizvi, T | 1 |
| Petersen, KD | 1 |
| Landsfeldt, U | 1 |
| Cold, GE | 1 |
| Petersen, CB | 1 |
| Mau, S | 1 |
| Hauerberg, J | 1 |
| Holst, P | 1 |
| Olsen, KS | 1 |
| Murr, R | 1 |
| Berger, S | 1 |
| Schürer, L | 1 |
| Peter, K | 1 |
| Baethmann, A | 1 |
| Hartung, J | 1 |
| Smith, AL | 1 |
| Marque, JJ | 1 |
| Tiznado, E | 1 |
| James, HE | 1 |
| Moore, S | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Influence of Vasopressors on Brain Oxygenation and Microcirculation in Anesthetized Patients With Cerebral Tumors[NCT02713087] | Phase 4 | 48 participants (Actual) | Interventional | 2015-09-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for fentanyl and Brain Swelling
| Article | Year |
|---|---|
Intracranial pressure and cerebral hemodynamic in patients with cerebral tumors: a randomized prospective study of patients subjected to craniotomy in propofol-fentanyl, isoflurane-fentanyl, or sevoflurane-fentanyl anesthesia.
Topics: Adolescent; Adult; Aged; Anesthesia, General; Anesthesia, Inhalation; Anesthetics, Inhalation; Anest | 2003 |
6 other studies available for fentanyl and Brain Swelling
| Article | Year |
|---|---|
Response to "Malignant cerebella edema in three-year-old girl following accidental opioid ingestion and fentanyl administration".
Topics: Analgesics, Opioid; Brain Edema; Cerebellum; Child, Preschool; Edema; Female; Fentanyl; Humans | 2020 |
Malignant cerebellar edema in three-year-old girl following accidental opioid ingestion and fentanyl administration.
Topics: Analgesics, Opioid; Brain Edema; Cerebellum; Child, Preschool; Drug Overdose; Female; Fentanyl; Huma | 2019 |
Influence of isoflurane, fentanyl, thiopental, and alpha-chloralose on formation of brain edema resulting from a focal cryogenic lesion.
Topics: Anesthetics; Animals; Brain; Brain Edema; Brain Injuries; Cerebrovascular Circulation; Chloralose; F | 1995 |
Isoflurane, fentanyl, thiopental, and brain edema.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Brain; Brain Edema; Chloralose; Fentanyl | 1996 |
Anesthetics and cerebral edema.
Topics: Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics; Animals; Brain; Brain Edema; Dogs; Dro | 1976 |
The effects of acute high dose fentanyl administration on experimental brain edema: analysis of intracranial pressure, systemic arterial pressure, central venous pressure and brain water content.
Topics: Animals; Behavior, Animal; Blood Pressure; Brain; Brain Chemistry; Brain Edema; Central Venous Press | 1986 |