Page last updated: 2024-10-27

fentanyl and Brain Disorders

fentanyl has been researched along with Brain Disorders in 15 studies

Fentanyl: A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078)
fentanyl : A monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of N-phenyl-1-(2-phenylethyl)piperidin-4-amine with propanoic acid.

Research Excerpts

ExcerptRelevanceReference
"This study compares the effects of propofol and fentanyl/N2O on spontaneous brain electrical activity, neurologic outcome, and neuronal damage due to incomplete cerebral ischemia in rats."3.68The effects of propofol on brain electrical activity, neurologic outcome, and neuronal damage following incomplete ischemia in rats. ( Albrecht, RF; Hoffman, WE; Kochs, E; Schulte am Esch, J; Thomas, C; Werner, C, 1992)
"We considered that delayed encephalopathy due to periodic anoxia caused by fentanyl intoxication occurred in the present patient; however, the neurological sequelae were relatively mild as compared with reported cases of carbon monoxide intoxication."1.34[Delayed encephalopathy following acute fentanyl intoxicication]. ( Kanda, T; Kawai, M; Morimatsu, M; Negoro, K; Ogasawara, J; Shimizu, F, 2007)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19908 (53.33)18.7374
1990's2 (13.33)18.2507
2000's4 (26.67)29.6817
2010's1 (6.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
McPherson, C1
Haslam, M1
Pineda, R1
Rogers, C1
Neil, JJ1
Inder, TE1
Shimizu, F1
Kawai, M1
Ogasawara, J1
Negoro, K1
Morimatsu, M1
Kanda, T1
Zukic, A1
Kelly, PJ1
Rudehill, A1
Gordon, E1
Grepe, A1
Widén, L1
Chiaretti, A1
Viola, L1
Pietrini, D1
Piastra, M1
Savioli, A1
Tortorolo, L1
Caldarelli, M1
Stoppa, F1
Di Rocco, C1
Balakrishnan, G1
Raudzens, P1
Samra, SK1
Song, K1
Boening, JA1
Bosek, V1
Jamerson, BD1
Warner, DS1
Sinz, EH1
Kofke, WA1
Garman, RH1
Vernhiet, J1
Renou, AM1
Orgogozo, JM1
Constant, P1
Caille, JM1
Kochs, E1
Hoffman, WE1
Werner, C1
Thomas, C1
Albrecht, RF1
Schulte am Esch, J1
Mele, D1
Consoletti, L1
Lattanzio, A1
Carrillo, E1
Janssen, L1
Vercauteren, M1
Hanegreefs, G1
Noorduin, H1
Jennett, WB1
Barker, J1
Fitch, W1
McDowall, DG1
Hunter, AR1
Cane, RD1
Boedts, DA1
Vandenhove, PT1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Anesthesiological Strategies in Elective Craniotomy: Randomized, Equivalence, Open Trial[NCT00741351]Phase 3411 participants (Actual)Interventional2007-12-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for fentanyl and Brain Disorders

ArticleYear
Drugs for producing dissociative states.
    International anesthesiology clinics, 1973,Spring, Volume: 11, Issue:1

    Topics: Anesthesia, Dental; Anesthetics; Anesthetics, Dissociative; Brain Diseases; Cardiac Catheterization;

1973

Trials

4 trials available for fentanyl and Brain Disorders

ArticleYear
Preemptive analgesia with tramadol and fentanyl in pediatric neurosurgery.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2000, Volume: 16, Issue:2

    Topics: Adolescent; Analgesics, Opioid; Anesthesia, General; Brain Diseases; Brain Neoplasms; Child; Child,

2000
A comparison of remifentanil and fentanyl in patients undergoing surgery for intracranial mass lesions.
    Anesthesia and analgesia, 2000, Volume: 91, Issue:1

    Topics: Anesthesia Recovery Period; Anesthetics, Intravenous; Brain Diseases; Female; Fentanyl; Hemodynamics

2000
Effect of anaesthesia on intracranial pressure in patients with space-occupying lesions.
    Lancet (London, England), 1969, Jan-11, Volume: 1, Issue:7585

    Topics: Adolescent; Adult; Aged; Anesthesia, Endotracheal; Benperidol; Blood Pressure; Blood Volume; Brain A

1969
Cerebral angiography: two anaesthetic techniques. A preliminary report.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1973, May-12, Volume: 47, Issue:18

    Topics: Adolescent; Adult; Aged; Anesthesia, General; Brain Diseases; Brain Neoplasms; Carbon Dioxide; Cereb

1973

Other Studies

10 other studies available for fentanyl and Brain Disorders

ArticleYear
Brain Injury and Development in Preterm Infants Exposed to Fentanyl.
    The Annals of pharmacotherapy, 2015, Volume: 49, Issue:12

    Topics: Analgesics, Opioid; Brain Diseases; Child Development; Female; Fentanyl; Humans; Hypnotics and Sedat

2015
[Delayed encephalopathy following acute fentanyl intoxicication].
    Rinsho shinkeigaku = Clinical neurology, 2007, Volume: 47, Issue:5

    Topics: Aged, 80 and over; Analgesics, Opioid; Brain Diseases; Female; Fentanyl; Humans; Self Medication

2007
Neuroleptic analgesia for stereotactic surgery.
    Applied neurophysiology, 1983, Volume: 46, Issue:1-4

    Topics: Brain Diseases; Droperidol; Fentanyl; Humans; Neuroleptanalgesia; Stereotaxic Techniques; Tomography

1983
The epileptogenicity of neurolept anaesthesia in patients during and after neuroradiological examinations with metrizamide.
    Acta anaesthesiologica Scandinavica, 1983, Volume: 27, Issue:4

    Topics: Adolescent; Adult; Aged; Brain Diseases; Child; Child, Preschool; Electroencephalography; Epilepsy;

1983
Phenytoin, midazolam, and naloxone protect against fentanyl-induced brain damage in rats.
    Anesthesia and analgesia, 2000, Volume: 91, Issue:6

    Topics: Analgesics, Opioid; Animals; Anticonvulsants; Blood Gas Analysis; Body Weight; Brain Diseases; Elect

2000
Effects of a diazepam-fentanyl mixture on cerebral blood flow and oxygen consumption in man.
    British journal of anaesthesia, 1978, Volume: 50, Issue:2

    Topics: Brain; Brain Diseases; Cerebrovascular Circulation; Diazepam; Fentanyl; Humans; Oxygen Consumption

1978
The effects of propofol on brain electrical activity, neurologic outcome, and neuronal damage following incomplete ischemia in rats.
    Anesthesiology, 1992, Volume: 76, Issue:2

    Topics: Animals; Brain; Brain Damage, Chronic; Brain Diseases; Brain Ischemia; Depression, Chemical; Electro

1992
[Total intravenous anesthesia with propofol-fentanyl in patients undergoing neurosurgery].
    Minerva anestesiologica, 1990, Volume: 56, Issue:9

    Topics: Adult; Aged; Anesthesia, Intravenous; Brain Diseases; Electroencephalography; Electromyography; Fema

1990
Low dose sufentanil for major intracranial surgery.
    Acta anaesthesiologica Belgica, 1989, Volume: 40, Issue:1

    Topics: Adult; Aged; Anesthesia Recovery Period; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetic

1989
Droperidol-fentanyl citrate in equilibratory distrubances.
    Archives of otolaryngology (Chicago, Ill. : 1960), 1969, Volume: 89, Issue:5

    Topics: Adult; Aged; Benperidol; Brain Diseases; Citrates; Diagnosis, Differential; Female; Fentanyl; Humans

1969