Page last updated: 2024-10-27

fentanyl and Brain Damage, Chronic

fentanyl has been researched along with Brain Damage, Chronic in 4 studies

Fentanyl: A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078)
fentanyl : A monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of N-phenyl-1-(2-phenylethyl)piperidin-4-amine with propanoic acid.

Brain Damage, Chronic: A condition characterized by long-standing brain dysfunction or damage, usually of three months duration or longer. Potential etiologies include BRAIN INFARCTION; certain NEURODEGENERATIVE DISORDERS; CRANIOCEREBRAL TRAUMA; ANOXIA, BRAIN; ENCEPHALITIS; certain NEUROTOXICITY SYNDROMES; metabolic disorders (see BRAIN DISEASES, METABOLIC); and other conditions.

Research Excerpts

ExcerptRelevanceReference
"This study compares the effects of propofol and fentanyl/N2O on spontaneous brain electrical activity, neurologic outcome, and neuronal damage due to incomplete cerebral ischemia in rats."3.68The effects of propofol on brain electrical activity, neurologic outcome, and neuronal damage following incomplete ischemia in rats. ( Albrecht, RF; Hoffman, WE; Kochs, E; Schulte am Esch, J; Thomas, C; Werner, C, 1992)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (50.00)18.2507
2000's2 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
De Jonghe, B1
Bastuji-Garin, S1
Fangio, P1
Lacherade, JC1
Jabot, J1
Appéré-De-Vecchi, C1
Rocha, N1
Outin, H1
Kofke, WA1
Garman, RH1
Stiller, RL1
Rose, ME1
Garman, R1
Kochs, E1
Hoffman, WE1
Werner, C1
Thomas, C1
Albrecht, RF1
Schulte am Esch, J1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Prevention of Oversedation in Intensive Care Patients Under Mechanical Ventilation : the AWARE Multicentric Randomized Trial[NCT01617265]1,180 participants (Actual)Interventional2012-06-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for fentanyl and Brain Damage, Chronic

ArticleYear
Sedation algorithm in critically ill patients without acute brain injury.
    Critical care medicine, 2005, Volume: 33, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Algorithms; Arousal; Brain Damage, Chronic; Conscious Sedation; Crit

2005

Other Studies

3 other studies available for fentanyl and Brain Damage, Chronic

ArticleYear
Pediatric emergency medicine: legal briefs.
    Pediatric emergency care, 2007, Volume: 23, Issue:3

    Topics: Acidosis; Administration, Cutaneous; Adult; Asphyxia; Brain Damage, Chronic; Burns, Chemical; Child;

2007
Opioid neurotoxicity: fentanyl dose-response effects in rats.
    Anesthesia and analgesia, 1996, Volume: 83, Issue:6

    Topics: Anesthetics, Inhalation; Animals; Blood Pressure; Body Temperature; Brain; Brain Damage, Chronic; Ce

1996
The effects of propofol on brain electrical activity, neurologic outcome, and neuronal damage following incomplete ischemia in rats.
    Anesthesiology, 1992, Volume: 76, Issue:2

    Topics: Animals; Brain; Brain Damage, Chronic; Brain Diseases; Brain Ischemia; Depression, Chemical; Electro

1992