fentanyl has been researched along with Bone Neoplasms in 24 studies
Fentanyl: A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078)
fentanyl : A monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of N-phenyl-1-(2-phenylethyl)piperidin-4-amine with propanoic acid.
Bone Neoplasms: Tumors or cancer located in bone tissue or specific BONES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Patients with bone-cancer pain, already on opioids, obtain clinically important, additional pain-control, with regular oxycodone/paracetamol dosing." | 9.16 | Efficacy of oxycodone/paracetamol for patients with bone-cancer pain: a multicenter, randomized, double-blinded, placebo-controlled trial. ( Fang, WX; Li, F; Sima, L; Wu, XM, 2012) |
| "To compare the effects of providing analgesia with either transdermal fentanyl (TTS-fentanyl) or paracetamol and codeine (P/C) in addition to radiotherapy in patients with metastatic bone pain." | 9.11 | Radiotherapy plus either transdermal fentanyl or paracetamol and codeine for painful bone metastases: a randomised study of pain relief and quality of life. ( Eleftheriadis, N; Georgakopoulos, G; Gompakis, N; Kouloulias, VE; Kouvaris, J; Mystakidou, K; Pistevou-Gompaki, K; Varveris, C, 2004) |
| " We treated a 50s female with pain and dyspnea from bone metastasis and lymphangitis carcinomatosa after surgery for NSCLC in whom the optimal dosages of transdermal fentanyl (Durotep Patch) were determined by titration with fentanyl injection, and oxycodone hydrochloride (OxyContin) in a short period." | 7.76 | [Successful management of a patient with pain and dyspnea from bone metastasis and lymphangitis carcinomatosa after surgery for non-small cell lung cancer (NSCLC) in whom optimal dosages of transdermal fentanyl were determined by titration with fentanyl i ( Eguchi, K; Gika, M; Inoue, Y; Izawa, N; Nakayama, M; Takeuchi, K, 2010) |
| " Our aim was to examine whether, fentanyl as well as morphine, two potent analgesic opioids commonly used to treat cancer pain, would inhibit pain and bone lesion-related responses in a murine model of bone cancer pain." | 7.74 | The impact of the opioids fentanyl and morphine on nociception and bone destruction in a murine model of bone cancer pain. ( El Mouedden, M; Meert, TF, 2007) |
| "The present study was conducted to evaluate the pain development and bone destruction during bone cancer growth in a murine model of bone cancer pain and to evaluate the analgesic efficacy of fentanyl, sufentanil, and morphine in this model." | 7.73 | Evaluation of pain-related behavior, bone destruction and effectiveness of fentanyl, sufentanil, and morphine in a murine model of cancer pain. ( El Mouedden, M; Meert, TF, 2005) |
| "The femur bone cancer pain model was developed by implanting mouse osteolytic tumor cells (NCTC 2472) into the intramedulla of the femur in C3H/HeN mice." | 5.35 | Oxycodone-induced analgesic effects in a bone cancer pain model in mice. ( Ito, H; Kato, A; Kihara, T; Matsumoto, M; Minami, K; Narita, M; Orita, S; Suzuki, T; Tomii, T, 2008) |
| "Patients with bone-cancer pain, already on opioids, obtain clinically important, additional pain-control, with regular oxycodone/paracetamol dosing." | 5.16 | Efficacy of oxycodone/paracetamol for patients with bone-cancer pain: a multicenter, randomized, double-blinded, placebo-controlled trial. ( Fang, WX; Li, F; Sima, L; Wu, XM, 2012) |
| "To compare the effects of providing analgesia with either transdermal fentanyl (TTS-fentanyl) or paracetamol and codeine (P/C) in addition to radiotherapy in patients with metastatic bone pain." | 5.11 | Radiotherapy plus either transdermal fentanyl or paracetamol and codeine for painful bone metastases: a randomised study of pain relief and quality of life. ( Eleftheriadis, N; Georgakopoulos, G; Gompakis, N; Kouloulias, VE; Kouvaris, J; Mystakidou, K; Pistevou-Gompaki, K; Varveris, C, 2004) |
| " We describe the case of a patient suffering from breaktrough cancer pain treated with sublingual fentanyl." | 3.91 | [Breaktrough cancer pain in metastatic prostate adenocarcinoma: a case report.] ( Miolo, G; Santeufemia, DA, 2019) |
| "This case describes an incident where a patient with breast cancer and bone metastases, who was using a fentanyl patch, was started on a course of clarithromycin and experienced a respiratory arrest 2 days later." | 3.78 | Fentanyl-clarithromycin interaction. ( Cronnolly, B; Pegrum, H, 2012) |
| " We treated a 50s female with pain and dyspnea from bone metastasis and lymphangitis carcinomatosa after surgery for NSCLC in whom the optimal dosages of transdermal fentanyl (Durotep Patch) were determined by titration with fentanyl injection, and oxycodone hydrochloride (OxyContin) in a short period." | 3.76 | [Successful management of a patient with pain and dyspnea from bone metastasis and lymphangitis carcinomatosa after surgery for non-small cell lung cancer (NSCLC) in whom optimal dosages of transdermal fentanyl were determined by titration with fentanyl i ( Eguchi, K; Gika, M; Inoue, Y; Izawa, N; Nakayama, M; Takeuchi, K, 2010) |
| "We report a case of serotonin syndrome caused by interaction between nasal fentanyl, oxycodone and escitalopram." | 3.76 | [Serotoninergic antidepressants and opiate analgesics: a sometimes-painful association. A case report]. ( Lefebvre-Kuntz, D; Reich, M, 2010) |
| " Our aim was to examine whether, fentanyl as well as morphine, two potent analgesic opioids commonly used to treat cancer pain, would inhibit pain and bone lesion-related responses in a murine model of bone cancer pain." | 3.74 | The impact of the opioids fentanyl and morphine on nociception and bone destruction in a murine model of bone cancer pain. ( El Mouedden, M; Meert, TF, 2007) |
| "The present study was conducted to evaluate the pain development and bone destruction during bone cancer growth in a murine model of bone cancer pain and to evaluate the analgesic efficacy of fentanyl, sufentanil, and morphine in this model." | 3.73 | Evaluation of pain-related behavior, bone destruction and effectiveness of fentanyl, sufentanil, and morphine in a murine model of cancer pain. ( El Mouedden, M; Meert, TF, 2005) |
| "Pain is the most feared symptom for patients diagnosed with cancer." | 2.40 | Current strategies for pain control. ( Ahmedzai, S, 1997) |
| " 33 patients in terminal stage of carcinoma, who had been treated by transdermal fentanyl due to their excruciating pain (7-10 mark on numerical scale) with initial dosage of 25 microg as a strong opiate analgesic, were monitored within the time period of 10 days." | 1.36 | Treatment of severe cancer pain by transdermal fentanyl. ( Husić, S; Ljuca, D, 2010) |
| "The femur bone cancer pain model was developed by implanting mouse osteolytic tumor cells (NCTC 2472) into the intramedulla of the femur in C3H/HeN mice." | 1.35 | Oxycodone-induced analgesic effects in a bone cancer pain model in mice. ( Ito, H; Kato, A; Kihara, T; Matsumoto, M; Minami, K; Narita, M; Orita, S; Suzuki, T; Tomii, T, 2008) |
| " In addition, the total daily dose of ketorolac was reduced following a change from intermittent bolus dosing to a continuous infusion." | 1.30 | Prolonged central intravenous ketorolac continuous infusion in a cancer patient with intractable bone pain. ( Gordon, RL, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (8.33) | 18.2507 |
| 2000's | 9 (37.50) | 29.6817 |
| 2010's | 12 (50.00) | 24.3611 |
| 2020's | 1 (4.17) | 2.80 |
| Authors | Studies |
|---|---|
| Baamonde, A | 1 |
| Menéndez, L | 1 |
| González-Rodríguez, S | 1 |
| Lastra, A | 1 |
| Seitz, V | 1 |
| Stein, C | 1 |
| Machelska, H | 1 |
| Prieto, I | 1 |
| Pardo, J | 1 |
| Luna, J | 1 |
| Marin, JP | 1 |
| Olivera, J | 1 |
| Garcia, AJ | 1 |
| Perez, AM | 1 |
| Westdorp, H | 1 |
| Kuip, EJM | 1 |
| van Oort, IM | 2 |
| Kramers, C | 1 |
| Gerritsen, WR | 1 |
| Vissers, KCP | 1 |
| Benoist, GE | 1 |
| Burger, DM | 1 |
| Koch, BCP | 1 |
| Mehra, N | 1 |
| van Erp, NP | 1 |
| Yousef, AA | 1 |
| Alzeftawy, AE | 1 |
| Santeufemia, DA | 1 |
| Miolo, G | 1 |
| Yoshitake, A | 1 |
| Yamamoto, T | 1 |
| Susaki, S | 1 |
| Abe, E | 1 |
| Kato, A | 1 |
| Minami, K | 1 |
| Ito, H | 1 |
| Tomii, T | 1 |
| Matsumoto, M | 1 |
| Orita, S | 1 |
| Kihara, T | 1 |
| Narita, M | 1 |
| Suzuki, T | 1 |
| Gika, M | 1 |
| Eguchi, K | 1 |
| Inoue, Y | 1 |
| Izawa, N | 1 |
| Takeuchi, K | 1 |
| Nakayama, M | 1 |
| Ljuca, D | 1 |
| Husić, S | 1 |
| Reich, M | 1 |
| Lefebvre-Kuntz, D | 1 |
| Sima, L | 1 |
| Fang, WX | 1 |
| Wu, XM | 1 |
| Li, F | 1 |
| Núñez-Olarte, JM | 1 |
| Alvarez-Jiménez, P | 1 |
| Cronnolly, B | 1 |
| Pegrum, H | 1 |
| Pistevou-Gompaki, K | 1 |
| Kouloulias, VE | 1 |
| Varveris, C | 1 |
| Mystakidou, K | 1 |
| Georgakopoulos, G | 1 |
| Eleftheriadis, N | 1 |
| Gompakis, N | 1 |
| Kouvaris, J | 1 |
| Bozkurt, P | 1 |
| Bakan, M | 1 |
| Kilinç, LT | 1 |
| El Mouedden, M | 2 |
| Meert, TF | 2 |
| Weinbroum, AA | 1 |
| Kamiya, N | 1 |
| Yasogawa, Y | 1 |
| Nishi, Y | 1 |
| Takahashi, Y | 1 |
| Kondo, Y | 1 |
| Hirai, T | 1 |
| Sakurai, M | 1 |
| Masumizu, K | 1 |
| Onosato, W | 1 |
| Koyama, T | 1 |
| Sasson, M | 1 |
| Shvartzman, P | 1 |
| Chen, CW | 1 |
| Chan, KH | 1 |
| Hsieh, CF | 1 |
| Tsou, MY | 1 |
| Tsao, CM | 1 |
| Ahmedzai, S | 1 |
| Gordon, RL | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Efficacy of Epidural Analgesia Initiated in the Preoperative Period in Lower Extremity Osteosarcoma[NCT04945512] | 28 participants (Anticipated) | Interventional | 2021-11-07 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for fentanyl and Bone Neoplasms
| Article | Year |
|---|---|
Current strategies for pain control.
Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Bone Neoplasms; Fentanyl; Humans; Neoplasms; Pain; Pai | 1997 |
5 trials available for fentanyl and Bone Neoplasms
| Article | Year |
|---|---|
Facilitation of accurate and effective radiation therapy using fentanyl pectin nasal spray (FPNS) to reduce incidental breakthrough pain due to procedure positioning.
Topics: Analgesics, Opioid; Bone Neoplasms; Breakthrough Pain; Fentanyl; Humans; Nasal Sprays; Pectins; Radi | 2016 |
The efficacy of oral piroxicam fast-dissolving tablets versus sublingual fentanyl in incident breakthrough pain due to bone metastases: a double-blinded randomized study.
Topics: Administration, Sublingual; Anti-Inflammatory Agents, Non-Steroidal; Bone Neoplasms; Breakthrough Pa | 2019 |
Efficacy of oxycodone/paracetamol for patients with bone-cancer pain: a multicenter, randomized, double-blinded, placebo-controlled trial.
Topics: Acetaminophen; Administration, Oral; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Bone Neopla | 2012 |
Radiotherapy plus either transdermal fentanyl or paracetamol and codeine for painful bone metastases: a randomised study of pain relief and quality of life.
Topics: Acetaminophen; Activities of Daily Living; Administration, Cutaneous; Aged; Aged, 80 and over; Analg | 2004 |
Superiority of postoperative epidural over intravenous patient-controlled analgesia in orthopedic oncologic patients.
Topics: Adult; Amides; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthesia, G | 2005 |
18 other studies available for fentanyl and Bone Neoplasms
| Article | Year |
|---|---|
A low pKa ligand inhibits cancer-associated pain in mice by activating peripheral mu-opioid receptors.
Topics: Analgesics, Opioid; Animals; Bone Neoplasms; Cancer Pain; Cell Line, Tumor; Fentanyl; Hydrogen-Ion C | 2020 |
Difficulties in Pain Management Using Oxycodone and Fentanyl in Enzalutamide-Treated Patients With Advanced Prostate Cancer.
Topics: Aged; Analgesics, Opioid; Antineoplastic Agents; Benzamides; Bone Neoplasms; Drug Interactions; Fent | 2018 |
The Combination of Enzalutamide and Opioids: A Painful Pitfall?
Topics: Analgesics, Opioid; Androgen Antagonists; Antineoplastic Agents; Benzamides; Bone Neoplasms; Cytochr | 2019 |
[Breaktrough cancer pain in metastatic prostate adenocarcinoma: a case report.]
Topics: Adenocarcinoma; Administration, Sublingual; Analgesics, Opioid; Bone Neoplasms; Breakthrough Pain; C | 2019 |
[Opioid combination of transdermal fentanyl and oral oxycodone for pain in a patient with giant-cell tumor of the sacrum].
Topics: Administration, Cutaneous; Administration, Oral; Adult; Analgesics, Opioid; Bone Neoplasms; Drug Adm | 2014 |
Oxycodone-induced analgesic effects in a bone cancer pain model in mice.
Topics: Analgesics; Analgesics, Opioid; Animals; Behavior, Animal; Bone Neoplasms; Disease Models, Animal; F | 2008 |
[Successful management of a patient with pain and dyspnea from bone metastasis and lymphangitis carcinomatosa after surgery for non-small cell lung cancer (NSCLC) in whom optimal dosages of transdermal fentanyl were determined by titration with fentanyl i
Topics: Administration, Cutaneous; Bone Neoplasms; Carcinoma, Non-Small-Cell Lung; Dyspnea; Female; Fentanyl | 2010 |
Treatment of severe cancer pain by transdermal fentanyl.
Topics: Administration, Cutaneous; Adult; Aged; Analgesics, Opioid; Bone Neoplasms; Female; Fentanyl; Hemody | 2010 |
[Serotoninergic antidepressants and opiate analgesics: a sometimes-painful association. A case report].
Topics: Adenocarcinoma; Administration, Intranasal; Administration, Oral; Aged; Analgesics, Opioid; Antidepr | 2010 |
Emerging opioid abuse in terminal cancer patients taking oral transmucosal fentanyl citrate for breakthrough pain.
Topics: Adult; Analgesics, Opioid; Bone Neoplasms; Breakthrough Pain; Fatal Outcome; Female; Fentanyl; Human | 2011 |
Fentanyl-clarithromycin interaction.
Topics: Aged; Analgesics, Opioid; Anti-Bacterial Agents; Bone Neoplasms; Breast Neoplasms; Clarithromycin; D | 2012 |
[Challenges in the treatment of pain in children with cancer and tunneling of epidural catheter for long term infusion].
Topics: Analgesia, Epidural; Analgesics, Opioid; Anesthetics, Local; Bone Neoplasms; Bupivacaine; Catheteriz | 2005 |
Evaluation of pain-related behavior, bone destruction and effectiveness of fentanyl, sufentanil, and morphine in a murine model of cancer pain.
Topics: Analgesics, Opioid; Animals; Behavior, Animal; Bone Neoplasms; Disease Models, Animal; Fentanyl; Mic | 2005 |
[A case of long-term, high-dose transdermal fentanyl application for lung cancer pain].
Topics: Administration, Cutaneous; Analgesics, Opioid; Bone Neoplasms; Female; Fentanyl; Humans; Lung Neopla | 2006 |
Fentanyl patch sufficient analgesia for only one day.
Topics: Administration, Cutaneous; Aged; Analgesics, Opioid; Bone Neoplasms; Fentanyl; Humans; Male; Pain; P | 2006 |
Low-dose bupivacaine-fentanyl spinal anesthesia for lower extremity surgery in a nonparturient with Eisenmenger's syndrome.
Topics: Adult; Analgesics, Opioid; Anesthesia, Spinal; Anesthetics, Local; Bone Neoplasms; Bupivacaine; Eise | 2007 |
The impact of the opioids fentanyl and morphine on nociception and bone destruction in a murine model of bone cancer pain.
Topics: Analgesics, Opioid; Animals; Behavior, Animal; Body Weight; Bone and Bones; Bone Neoplasms; Femur; F | 2007 |
Prolonged central intravenous ketorolac continuous infusion in a cancer patient with intractable bone pain.
Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Bone Neoplasms; Carcinoma, Non-Small-Cell Lung; Cathet | 1998 |