fentanyl has been researched along with Body Weight in 77 studies
Fentanyl: A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078)
fentanyl : A monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of N-phenyl-1-(2-phenylethyl)piperidin-4-amine with propanoic acid.
Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In this prospective, randomized, double-blind study, we compared the efficacy and safety of ondansetron and metoclopramide in the treatment of postoperative nausea and vomiting (PONV)." | 9.08 | Ondansetron versus metoclopramide in the treatment of postoperative nausea and vomiting. ( Finco, G; Gottin, L; Grosso, S; Ischia, S; Mosaner, W; Pinaroli, AM; Polati, E; Verlato, G, 1997) |
| "Transdermal fentanyl is effective and well tolerated for the treatment of chronic pain caused by malignancy and non-malignant conditions when administered according to the manufacturer's recommendations." | 8.82 | Benefit-risk assessment of transdermal fentanyl for the treatment of chronic pain. ( Kornick, CA; Moryl, N; Obbens, EA; Payne, R; Santiago-Palma, J, 2003) |
| "We carried out a retrospective investigation on the effect of obesity on dexmedetomidine (DEX) requirements when administered with fentanyl (FEN) during mechanical ventilation after major surgeries." | 7.81 | THE EFFECT OF OBESITY ON DOSE OF DEXMEDETOMIDINE WHEN ADMINISTERED WITH FENTANYL DURING POSTOPERATIVE MECHANICAL VENTILATION--RETROSPECTIVE. ( Hakozaki, T; Hosono, A; Imaizumi, T; Iseki, Y; Isosu, T; Mogami, M; Morimoto, I; Murakawa, M; Nakano, Y; Obara, S; Oishi, R, 2015) |
| " Our aim was to examine whether, fentanyl as well as morphine, two potent analgesic opioids commonly used to treat cancer pain, would inhibit pain and bone lesion-related responses in a murine model of bone cancer pain." | 7.74 | The impact of the opioids fentanyl and morphine on nociception and bone destruction in a murine model of bone cancer pain. ( El Mouedden, M; Meert, TF, 2007) |
| "During a fixed infusion rate, plasma propofol concentration may be dependent on total body weight." | 7.70 | Is total body weight an appropriate predictor for propofol maintenance dose? ( Ebina, T; Hirota, K; Ishihara, H; Matsuki, A; Sato, T, 1999) |
| " NMDA receptor antagonists versus no treatment, placebo, oral sweet solution, or non-pharmacological intervention One RCT evaluated using oral ketamine (10 mg/kg body weight) versus sugar syrup (66." | 5.41 | Non-opioid analgesics for procedural pain in neonates. ( Bruschettini, M; Persad, E; Pizarro, AB, 2023) |
| " Total dose of fentanyl per body weight in the post-anesthesia care unit was also higher in the HYPO (0." | 5.34 | Effect of intraoperative Hartmann's versus hypotonic solution administration on FLACC pain scale scores in children: A prospective randomized controlled trial. ( Chae, MS; Kim, M; Lee, H; Lee, J; Lee, M; Yang, S, 2020) |
| "Actual body weight overestimates fentanyl dose requirements in obese patients." | 5.11 | Accuracy of pharmacokinetic models for predicting plasma fentanyl concentrations in lean and obese surgical patients: derivation of dosing weight ("pharmacokinetic mass"). ( Bairamian, M; Inchiosa, MA; Sawada, K; Shibutani, K, 2004) |
| " fentanyl (50 micrograms/kg of body weight) and transdermal fentanyl (50 micrograms/h) administrations." | 5.08 | Disposition of transdermally administered fentanyl in dogs. ( Hardie, EM; Kyles, AE; Papich, M, 1996) |
| " Despite the same duration of preoxygenation, younger children were more susceptible than elder ones to the risk of hypoxemia during apnea." | 5.08 | Study of the safe threshold of apneic period in children during anesthesia induction. ( An, G; Deng, XM; Liao, X; Luo, LK; Tong, SY; Xue, FS, 1996) |
| "In this prospective, randomized, double-blind study, we compared the efficacy and safety of ondansetron and metoclopramide in the treatment of postoperative nausea and vomiting (PONV)." | 5.08 | Ondansetron versus metoclopramide in the treatment of postoperative nausea and vomiting. ( Finco, G; Gottin, L; Grosso, S; Ischia, S; Mosaner, W; Pinaroli, AM; Polati, E; Verlato, G, 1997) |
| "Transdermal fentanyl is effective and well tolerated for the treatment of chronic pain caused by malignancy and non-malignant conditions when administered according to the manufacturer's recommendations." | 4.82 | Benefit-risk assessment of transdermal fentanyl for the treatment of chronic pain. ( Kornick, CA; Moryl, N; Obbens, EA; Payne, R; Santiago-Palma, J, 2003) |
| "We carried out a retrospective investigation on the effect of obesity on dexmedetomidine (DEX) requirements when administered with fentanyl (FEN) during mechanical ventilation after major surgeries." | 3.81 | THE EFFECT OF OBESITY ON DOSE OF DEXMEDETOMIDINE WHEN ADMINISTERED WITH FENTANYL DURING POSTOPERATIVE MECHANICAL VENTILATION--RETROSPECTIVE. ( Hakozaki, T; Hosono, A; Imaizumi, T; Iseki, Y; Isosu, T; Mogami, M; Morimoto, I; Murakawa, M; Nakano, Y; Obara, S; Oishi, R, 2015) |
| "Thus, the present preclinical study assessed the effectiveness of chronic fentanyl administration to produce antinociception in aging rats (16, 20, and 24 months)." | 3.80 | Thermal sensitivity across ages and during chronic fentanyl administration in rats. ( Carter, CS; Mitzelfelt, JD; Morgan, D, 2014) |
| " Our aim was to examine whether, fentanyl as well as morphine, two potent analgesic opioids commonly used to treat cancer pain, would inhibit pain and bone lesion-related responses in a murine model of bone cancer pain." | 3.74 | The impact of the opioids fentanyl and morphine on nociception and bone destruction in a murine model of bone cancer pain. ( El Mouedden, M; Meert, TF, 2007) |
| "We previously proposed dosing weights for fentanyl, termed 'pharmacokinetic mass', that span the total body weight (TBW) range from 40 to 210 kg." | 3.73 | Pharmacokinetic mass of fentanyl for postoperative analgesia in lean and obese patients. ( Bairamian, M; Inchiosa, MA; Sawada, K; Shibutani, K, 2005) |
| "During a fixed infusion rate, plasma propofol concentration may be dependent on total body weight." | 3.70 | Is total body weight an appropriate predictor for propofol maintenance dose? ( Ebina, T; Hirota, K; Ishihara, H; Matsuki, A; Sato, T, 1999) |
| "To investigate the relationship between total body weight (TBW) or body mass index (BMI) and atracurium reversal time." | 3.70 | Antagonism of atracurium-induced block in obese patients. ( Kirkegaard-Nielsen, H; Lindholm, P; Petersen, HS; Severinsen, IK, 1998) |
| "The extent of atelectasis was correlated to constitutional factors in 38 patients who underwent computed tomography prior to and during general anaesthesia with halothane." | 3.67 | Constitutional factors promoting development of atelectasis during anaesthesia. ( Brismar, B; Hedenstierna, G; Lundquist, H; Strandberg, A; Tokics, L, 1987) |
| "Fentanyl 25 microg was then delivered via this system twice during the first 20 minutes of every hour for 24 hours." | 2.71 | Effects of application site and subject demographics on the pharmacokinetics of fentanyl HCl patient-controlled transdermal system (PCTS). ( Gupta, SK; Hwang, S; Sathyan, G; Southam, M, 2005) |
| "Midazolam was associated with impairment of performance on the TDT and DSST after premedication administration and 15 (TDT and DSST) and 30 (DSST) min after postanesthesia care unit (PACU) arrival." | 2.68 | Midazolam premedication increases sedation but does not prolong discharge times after brief outpatient general anesthesia for laparoscopic tubal sterilization. ( Hussain, A; Richardson, MG; Wu, CL, 1997) |
| "The combination of fentanyl and droperidol, Innovar, was compared to flunitrazepam (1-2 mg) in a higher dosage (2." | 2.65 | [High-dose thalamonal-rohypnol for premedication. A randomized double-blind study]. ( Schmidt, R; Tolksdorf, W; Wagener, M, 1984) |
| "Drug dosing in infants frequently depends on body weight as a crude indicator for maturation." | 2.58 | Drug metabolism in early infancy: opioids as an illustration. ( Allegaert, K; Mian, P; Tibboel, D; Van Den Anker, J; Van Donge, T, 2018) |
| " Given the limited pharmacokinetic information across the entire neonatal age range, we characterized the pharmacokinetics of fentanyl across preterm and term neonates to individualize dosing." | 1.72 | Pre- and Postnatal Maturation are Important for Fentanyl Exposure in Preterm and Term Newborns: A Pooled Population Pharmacokinetic Study. ( Allegaert, K; Fellman, V; Flint, RB; Knibbe, CAJ; Simons, SHP; Völler, S; Wu, Y, 2022) |
| "Fentanyl (20 μg/kg) was administered IV." | 1.48 | Pharmacokinetics of fentanyl after intravenous administration in isoflurane-anesthetized red-tailed hawks (Buteo jamaicensis) and Hispaniolan Amazon parrots (Amazona ventralis). ( DiMaio Knych, HK; Hawkins, MG; Pascoe, PJ; Pavez Phillips, JC; Pypendop, BH; Sanchez-Migallon Guzman, D, 2018) |
| "No significant decrease in dosing between age groups was observed for fentanyl and midazolam." | 1.43 | Does intravenous induction dosing among patients undergoing gastrointestinal surgical procedures follow current recommendations: a study of contemporary practice. ( Akhtar, S; Burg, MM; Dai, F; Heng, J; Liu, J; Schonberger, RB, 2016) |
| " Initial dosage regimens in this population are often empirically derived from adults on a body weight basis." | 1.39 | A predictive pharmacokinetic/pharmacodynamic model of fentanyl for analgesia/sedation in neonates based on a semi-physiologic approach. ( Calvo, R; Encinas, E; Lukas, JC; Rodriguez, M; Suarez, E; Vozmediano, V, 2013) |
| " Mean (SD) peak concentration of fentanyl was 1." | 1.31 | Pharmacokinetics of transdermal fentanyl in the peri-operative period in young children. ( Camboulives, J; Lemoing, JP; Levron, JC; Paut, O; Viard, L, 2000) |
| " The pharmacokinetic differences may be related to the differences in the sensitivity to vecuronium between genders." | 1.30 | The pharmacokinetics of vecuronium in male and female patients. ( An, G; Liao, X; Luo, LK; Xue, FS; Zou, Q, 1998) |
| "The fentanyl infusion was decreased by 1 microg/kg/hr every 12-24 hrs and the midazolam infusion was decreased by 0." | 1.30 | Subcutaneous administration of fentanyl and midazolam to prevent withdrawal after prolonged sedation in children. ( Tobias, JD, 1999) |
| "Sensitivity and specificity were 50% and 97%, respectively." | 1.29 | Factors associated with hypotension and bradycardia after epidural blockade. ( Curatolo, M; Orlando, A; Scaramozzino, P; Venuti, FS; Zbinden, AM, 1996) |
| " One week later, 24 hr after removing the osmotic pumps, cumulative dose-response curves for fentanyl analgesia were generated in the presence of 0." | 1.28 | Apparent pA2 value of naltrexone is not changed in rats following continuous exposure to morphine or naloxone. ( Holtzman, SG; Paronis, CA, 1992) |
| "Morphine and fentanyl treatment, beginning at postnatal day 22, delayed the time of the first ovulation/vaginal opening (VO)." | 1.28 | Occurrence of sexual maturation in chronic opiate-treated female rats. ( MacDonald, MC; Wilkinson, M, 1991) |
| " Pharmacokinetic parameters were estimated by a model-independent approach and by curve-fitting." | 1.28 | Pharmacokinetics of alfentanil during and after a fixed rate infusion. ( Crul, J; Gasparini, R; Heykants, J; Noorduin, H; Van Beem, H; Van Egmond, J; Van Peer, A; Woestenborghs, R, 1989) |
| "Naloxone did, however, suppress FI and WI following deprivation and inhibited the recovery of body weight thereafter." | 1.27 | Long-term blockade of mu-opioid receptors suggests a role in control of ingestive behaviour, body weight and core temperature in the rat. ( Millan, MJ; Morris, BJ, 1988) |
| " Maintenance dosage of propofol sufficient to abolish movement decreased with increasing age (p less than 0." | 1.27 | Intravenous anaesthesia with propofol and alfentanil. The influence of age and weight. ( Dev, VJ; Hilton, P; Major, E, 1986) |
| "The population pharmacokinetic parameters describing the plasma concentration versus time profile of alfentanil in patients undergoing general anesthesia were determined from 614 plasma concentration measurements collected in four previously reported studies with a total of 45 patients." | 1.27 | Population pharmacokinetics of alfentanil: the average dose-plasma concentration relationship and interindividual variability in patients. ( Heykants, J; Maitre, PO; Stanski, DR; Thomson, DA; Vozeh, S, 1987) |
| " Pharmacokinetic values were independent of dose." | 1.27 | The pharmacokinetics of alfentanil in children. ( Goresky, GV; Koren, G; Sabourin, MA; Sale, JP; Strunin, L, 1987) |
| "The calculation of pharmacokinetic parameters after a bolus injection of fentanyl allowed an i." | 1.26 | Infusion model for fentanyl based on pharmacokinetic analysis. ( Hengstmann, JH; Schüttler, J; Stoeckel, H, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 25 (32.47) | 18.7374 |
| 1990's | 18 (23.38) | 18.2507 |
| 2000's | 17 (22.08) | 29.6817 |
| 2010's | 14 (18.18) | 24.3611 |
| 2020's | 3 (3.90) | 2.80 |
| Authors | Studies |
|---|---|
| Wu, Y | 1 |
| Völler, S | 1 |
| Flint, RB | 1 |
| Simons, SHP | 1 |
| Allegaert, K | 2 |
| Fellman, V | 1 |
| Knibbe, CAJ | 1 |
| Persad, E | 1 |
| Pizarro, AB | 1 |
| Bruschettini, M | 1 |
| Kim, M | 1 |
| Lee, J | 1 |
| Yang, S | 1 |
| Lee, M | 1 |
| Chae, MS | 1 |
| Lee, H | 1 |
| Van Donge, T | 1 |
| Mian, P | 1 |
| Tibboel, D | 1 |
| Van Den Anker, J | 1 |
| Trifa, M | 1 |
| Tumin, D | 1 |
| Whitaker, EE | 1 |
| Bhalla, T | 1 |
| Jayanthi, VR | 1 |
| Tobias, JD | 2 |
| Pascoe, PJ | 1 |
| Pypendop, BH | 1 |
| Pavez Phillips, JC | 1 |
| DiMaio Knych, HK | 1 |
| Sanchez-Migallon Guzman, D | 1 |
| Hawkins, MG | 1 |
| Encinas, E | 1 |
| Calvo, R | 1 |
| Lukas, JC | 1 |
| Vozmediano, V | 1 |
| Rodriguez, M | 1 |
| Suarez, E | 1 |
| Mitzelfelt, JD | 2 |
| Carter, CS | 2 |
| Morgan, D | 2 |
| Nath, SS | 1 |
| Tripathi, M | 1 |
| Banerjee, S | 1 |
| Nacitarhan, C | 1 |
| Minareci, E | 1 |
| Sadan, G | 1 |
| Baumunk, D | 1 |
| Strang, CM | 1 |
| Kropf, S | 1 |
| Schäfer, M | 1 |
| Schrader, M | 1 |
| Weikert, S | 1 |
| Cash, H | 1 |
| Breckwoldt, J | 1 |
| Miller, K | 1 |
| Hachenberg, T | 1 |
| Schostak, M | 1 |
| Obara, S | 1 |
| Morimoto, I | 1 |
| Iseki, Y | 1 |
| Oishi, R | 1 |
| Mogami, M | 1 |
| Imaizumi, T | 1 |
| Hosono, A | 1 |
| Hakozaki, T | 1 |
| Nakano, Y | 1 |
| Isosu, T | 1 |
| Murakawa, M | 1 |
| Akhtar, S | 1 |
| Liu, J | 1 |
| Heng, J | 1 |
| Dai, F | 1 |
| Schonberger, RB | 1 |
| Burg, MM | 1 |
| Herd, D | 1 |
| Borland, M | 1 |
| Dupree, JP | 1 |
| Seo, DO | 1 |
| Tramullas, M | 1 |
| Dinan, TG | 1 |
| Cryan, JF | 1 |
| Yucel, A | 1 |
| Gulhas, N | 1 |
| Aydogan, MS | 1 |
| Erdogan, MA | 1 |
| Beytur, A | 1 |
| Tasdemir, C | 1 |
| Ersoy, MO | 1 |
| Nardi, GM | 1 |
| Bet, AC | 1 |
| Sordi, R | 1 |
| Fernandes, D | 1 |
| Assreuy, J | 1 |
| Tamura, M | 1 |
| Nakamura, K | 1 |
| Kitamura, R | 1 |
| Kitagawa, S | 1 |
| Mori, N | 1 |
| Ueda, Y | 1 |
| Kornick, CA | 1 |
| Santiago-Palma, J | 1 |
| Moryl, N | 1 |
| Payne, R | 1 |
| Obbens, EA | 1 |
| Shibutani, K | 2 |
| Inchiosa, MA | 2 |
| Sawada, K | 2 |
| Bairamian, M | 2 |
| Lepere, AJ | 1 |
| Slack-Smith, LM | 1 |
| Pandey, CK | 1 |
| Navkar, DV | 1 |
| Giri, PJ | 1 |
| Raza, M | 1 |
| Behari, S | 1 |
| Singh, RB | 1 |
| Singh, U | 1 |
| Singh, PK | 1 |
| Gupta, SK | 1 |
| Hwang, S | 1 |
| Southam, M | 1 |
| Sathyan, G | 1 |
| El Mouedden, M | 1 |
| Meert, TF | 1 |
| Ishiyama, T | 1 |
| Iijima, T | 1 |
| Sugawara, T | 1 |
| Shibuya, K | 1 |
| Sato, H | 1 |
| Terada, Y | 1 |
| Ichikawa, M | 1 |
| Sessler, DI | 1 |
| Matsukawa, T | 1 |
| Boulard, G | 1 |
| Nicod, J | 1 |
| Scontrini, G | 1 |
| Sabathié, M | 1 |
| Tolksdorf, W | 1 |
| Wagener, M | 1 |
| Schmidt, R | 1 |
| Colpaert, FC | 1 |
| Meert, T | 1 |
| De Witte, P | 1 |
| Schmitt, P | 1 |
| Gelfman, SS | 1 |
| Gracely, RH | 1 |
| Driscoll, EJ | 1 |
| Butler, D | 1 |
| Sweet, JB | 1 |
| Wirdzek, PR | 1 |
| Marty, J | 1 |
| Desmonts, JM | 1 |
| Hengstmann, JH | 1 |
| Stoeckel, H | 1 |
| Schüttler, J | 1 |
| Danel, V | 1 |
| Gonod, E | 1 |
| Pomet, D | 1 |
| Curatolo, M | 2 |
| Orlando, A | 2 |
| Zbinden, AM | 2 |
| Scaramozzino, P | 2 |
| Venuti, FS | 2 |
| Shaham, Y | 1 |
| Klein, LC | 2 |
| Alvares, K | 1 |
| Grunberg, NE | 1 |
| Kyles, AE | 1 |
| Papich, M | 1 |
| Hardie, EM | 1 |
| Chan, A | 1 |
| Nickoll, E | 1 |
| Thornton, C | 1 |
| Doré, C | 1 |
| Newton, DE | 1 |
| Xue, FS | 2 |
| Luo, LK | 2 |
| Tong, SY | 1 |
| Liao, X | 2 |
| Deng, XM | 1 |
| An, G | 2 |
| Richardson, MG | 1 |
| Wu, CL | 1 |
| Hussain, A | 1 |
| Polati, E | 1 |
| Verlato, G | 1 |
| Finco, G | 1 |
| Mosaner, W | 1 |
| Grosso, S | 1 |
| Gottin, L | 1 |
| Pinaroli, AM | 1 |
| Ischia, S | 1 |
| Miller, DK | 1 |
| Nation, JR | 1 |
| Kirkegaard-Nielsen, H | 1 |
| Lindholm, P | 1 |
| Petersen, HS | 1 |
| Severinsen, IK | 1 |
| Zou, Q | 1 |
| Dunbar, PJ | 1 |
| Visco, E | 1 |
| Lam, AM | 1 |
| Hirota, K | 1 |
| Ebina, T | 1 |
| Sato, T | 1 |
| Ishihara, H | 1 |
| Matsuki, A | 1 |
| Skehan, SJ | 1 |
| Malone, DE | 1 |
| Buckley, N | 1 |
| Matsumoto, S | 1 |
| Rawlinson, J | 1 |
| Ting, G | 1 |
| Graham, D | 1 |
| Alexander, J | 1 |
| Somers, S | 1 |
| Stevenson, GW | 1 |
| Sinz, EH | 1 |
| Kofke, WA | 1 |
| Garman, RH | 1 |
| Paut, O | 1 |
| Camboulives, J | 1 |
| Viard, L | 1 |
| Lemoing, JP | 1 |
| Levron, JC | 1 |
| Fendt, M | 1 |
| Mucha, RF | 2 |
| Morgan, AD | 1 |
| Campbell, UC | 1 |
| Fons, RD | 1 |
| Carroll, ME | 1 |
| Lehmann, KA | 1 |
| Daub, D | 1 |
| Schuermans, V | 1 |
| Dom, J | 1 |
| Dony, J | 1 |
| Scheijgrond, H | 1 |
| Brugmans, J | 1 |
| Moraga Ramos, I | 1 |
| García Montero, A | 1 |
| Pérez del Palomar, R | 1 |
| Goñi Benzunegi, A | 1 |
| Sánchez García, A | 1 |
| Belloso Monguillot, M | 1 |
| Paronis, CA | 1 |
| Holtzman, SG | 1 |
| Walker, MJ | 1 |
| Fassos, FF | 1 |
| MacDonald, MC | 1 |
| Wilkinson, M | 1 |
| Hall, GM | 1 |
| Lacoumenta, S | 1 |
| Hart, GR | 1 |
| Burrin, JM | 1 |
| Van Beem, H | 1 |
| Van Peer, A | 1 |
| Gasparini, R | 1 |
| Woestenborghs, R | 1 |
| Heykants, J | 2 |
| Noorduin, H | 1 |
| Van Egmond, J | 1 |
| Crul, J | 1 |
| Eisenach, JC | 1 |
| Plevak, DJ | 1 |
| Van Dyke, RA | 1 |
| Southorn, PA | 1 |
| Danielson, DR | 1 |
| Krom, RA | 1 |
| Nagorney, DM | 1 |
| Rettke, SR | 1 |
| Millan, MJ | 1 |
| Morris, BJ | 1 |
| Hilton, P | 1 |
| Dev, VJ | 1 |
| Major, E | 1 |
| Maitre, PO | 1 |
| Vozeh, S | 1 |
| Thomson, DA | 1 |
| Stanski, DR | 1 |
| Goresky, GV | 1 |
| Koren, G | 1 |
| Sabourin, MA | 1 |
| Sale, JP | 1 |
| Strunin, L | 1 |
| Mazze, RI | 1 |
| Fujinaga, M | 1 |
| Baden, JM | 1 |
| Strandberg, A | 1 |
| Tokics, L | 1 |
| Brismar, B | 1 |
| Lundquist, H | 1 |
| Hedenstierna, G | 1 |
| Leiman, BC | 1 |
| Braude, BM | 1 |
| Galloway, PA | 1 |
| Van Hasselt, CH | 1 |
| Moyes, DG | 1 |
| Luis Ceraso, O | 1 |
| Carlos Giménez, J | 1 |
| Ceraso, OL | 1 |
| Guzzo, FJ | 1 |
| Guatta Cescuni, GH | 1 |
| Gimenez, JC | 1 |
| Curtis, JL | 1 |
| Browne, RA | 1 |
| Catton, DV | 1 |
| McIntyre, JW | 1 |
| Pichlmayr, I | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Comparison of Oral Gabapentin and Pregabalin in Postoperative Pain Control After Photorefractive Keratectomy: a Prospective, Randomized Study.[NCT00954187] | 8 participants (Actual) | Interventional | 2009-11-30 | Terminated (stopped due to PI left institution) | |||
| Gabapentin Regimens and Their Effects on Opioid Consumption[NCT03334903] | Phase 4 | 77 participants (Actual) | Interventional | 2018-05-15 | Completed | ||
| Gabapentin as a Pre-emptive Analgesic in Oral and Maxillofacial Surgical Procedures[NCT02957097] | Phase 4 | 0 participants (Actual) | Interventional | 2019-09-30 | Withdrawn (stopped due to Original PI left institution and the PI who took over was not able to initiate the study so it was never started.) | ||
| The Effect of Gabapentin on Acute Pain and PONV in Bariatric Surgical Patients[NCT00886236] | 62 participants (Actual) | Interventional | 2008-02-29 | Completed | |||
| Comparison of the Analgesic Effects of Scalp Nerve Block and Intravenous Ibuprofen Applications Under the Guidance of Nociception Level Index (NoL) in Patients Undergoing Elective Supratentorial Craniotomy[NCT05763836] | Phase 4 | 102 participants (Anticipated) | Interventional | 2022-11-01 | Recruiting | ||
| Continous Intravenous Lidocaine Infusion Intraoperative for Craniotomy Tumor Removal Surgery: Effect to Brain Relaxation, Opioid Consumption and Postoperative Cognitive Status[NCT04773093] | Phase 1/Phase 2 | 50 participants (Anticipated) | Interventional | 2021-01-01 | Recruiting | ||
| A Hydromorphone High Resolution Pharmacokinetic-Pharmacodynamic Fingerprint as the Basis for Identifying Sex Differences in Opioid Pharmacokinetics and Pharmacodynamics[NCT01123486] | 0 participants (Actual) | Interventional | 2015-01-31 | Withdrawn (stopped due to PI relocated to new university) | |||
| Feasibility of Upright Bed Position in ARDS Patients[NCT02160561] | 10 participants (Actual) | Interventional | 2013-04-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Surgical site pain. Scale 0-10, with 0 best and 10 worst (NCT03334903)
Timeframe: 2-3 months after surgery (at 2nd postoperative appointment)
| Intervention | score on 10-point scale (Mean) |
|---|---|
| Standard of Care | 2.26 |
| Postoperative Gabapentin Regimen | 2.46 |
Surgical site pain. Scale 0-10, with 0 best and 10 worst. (NCT03334903)
Timeframe: 2-3 months following surgery (measured at second postoperative appointment).
| Intervention | score on a 10-point scale (Mean) |
|---|---|
| Standard of Care | 3.84 |
| Postoperative Gabapentin Regimen | 3.54 |
Sleep quality. Scale 0-10 with 0 worst and 10 best. (NCT03334903)
Timeframe: 2-3 months following surgery (measured at second postoperative appointment).
| Intervention | score on a 10-point scale (Mean) |
|---|---|
| Standard of Care | 5.73 |
| Postoperative Gabapentin Regimen | 6.38 |
Nausea. Scale 0-10, with 0 best and 10 worst. (NCT03334903)
Timeframe: 2-3 months following surgery (measured at second postoperative appointment).
| Intervention | score on a 10-point scale (Mean) |
|---|---|
| Standard of Care | 0.36 |
| Postoperative Gabapentin Regimen | 0.17 |
Satisfaction. Scale 0-10 with 0 worst and 10 best. (NCT03334903)
Timeframe: 2-3 months following surgery (measured at second postoperative appointment).
| Intervention | score on a 10-point scale (Mean) |
|---|---|
| Standard of Care | 7.83 |
| Postoperative Gabapentin Regimen | 8.48 |
Number of days until patients are finished consuming opioid medications after discharge. (NCT03334903)
Timeframe: 2-3 months following surgery (measured at second postoperative appointment).
| Intervention | days (Mean) |
|---|---|
| Standard of Care | 14.8 |
| Postoperative Gabapentin Regimen | 18.7 |
Mean opioid consumption, measured in mg of morphine equivalents. (NCT03334903)
Timeframe: 2-3 months following surgery (total amount measured at second postoperative appointment; means assessed afterwards).
| Intervention | morphine equivalents (Mean) |
|---|---|
| Standard of Care | 287.0 |
| Postoperative Gabapentin Regimen | 281.1 |
(NCT00886236)
Timeframe: 48 hours
| Intervention | % oxygen saturation (Mean) |
|---|---|
| 1 Preoperative Gabapentin Liquid | 93 |
| 2 Preoperative and Postoperative Gabapentin Liquid | 94 |
| 3 Preoperative and Postoperative Placebo Liquid | 95 |
The amount of intraoperative and postoperative opioids used will be collected and analyzed for the three different arms. (NCT00886236)
Timeframe: 120 hours
| Intervention | ml (Mean) |
|---|---|
| 1 Preoperative Gabapentin Liquid | 11.035 |
| 2 Preoperative and Postoperative Gabapentin Liquid | 8.7 |
| 3 Preoperative and Postoperative Placebo Liquid | 12.4 |
(NCT00886236)
Timeframe: 120 hours
| Intervention | Participants (Count of Participants) |
|---|---|
| 1 Preoperative Gabapentin Liquid | 12 |
| 2 Preoperative and Postoperative Gabapentin Liquid | 11 |
| 3 Preoperative and Postoperative Placebo Liquid | 12 |
3 reviews available for fentanyl and Body Weight
| Article | Year |
|---|---|
Non-opioid analgesics for procedural pain in neonates.
Topics: Aged; Analgesics; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Apnea; Body Wei | 2023 |
Drug metabolism in early infancy: opioids as an illustration.
Topics: Age Factors; Analgesics, Opioid; Body Weight; Cytochrome P-450 CYP3A; Dose-Response Relationship, Dr | 2018 |
Benefit-risk assessment of transdermal fentanyl for the treatment of chronic pain.
Topics: Administration, Cutaneous; Analgesics, Opioid; Body Weight; Chronic Disease; Female; Fentanyl; Human | 2003 |
15 trials available for fentanyl and Body Weight
| Article | Year |
|---|---|
Effect of intraoperative Hartmann's versus hypotonic solution administration on FLACC pain scale scores in children: A prospective randomized controlled trial.
Topics: Blood Glucose; Body Weight; Child; Child, Preschool; Female; Fentanyl; Humans; Hypotonic Solutions; | 2020 |
Impact of thoracic epidural analgesia on blood loss in radical retropubic prostatectomy.
Topics: Administration, Intravenous; Aged; Analgesia, Epidural; Analgesics, Opioid; Anesthesia, General; Ane | 2014 |
Single intrathecal fentanyl for combined spinal epidural anesthesia confers no advantage over hemodynamic effects in elderly patients.
Topics: Aged; Aged, 80 and over; Aging; Anesthesia, Epidural; Anesthesia, Spinal; Anesthetics, Intravenous; | 2012 |
Oral premedication with fentanyl may be a safe and effective alternative to oral midazolam.
Topics: Adjuvants, Anesthesia; Administration, Oral; Age Distribution; Body Weight; Child, Preschool; Consci | 2003 |
Accuracy of pharmacokinetic models for predicting plasma fentanyl concentrations in lean and obese surgical patients: derivation of dosing weight ("pharmacokinetic mass").
Topics: Aged; Anesthesia, Intravenous; Anesthetics, Intravenous; Body Mass Index; Body Surface Area; Body We | 2004 |
Evaluation of the optimal preemptive dose of gabapentin for postoperative pain relief after lumbar diskectomy: a randomized, double-blind, placebo-controlled study.
Topics: Adult; Amines; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Body Weight; Cyclohexa | 2005 |
Evaluation of the optimal preemptive dose of gabapentin for postoperative pain relief after lumbar diskectomy: a randomized, double-blind, placebo-controlled study.
Topics: Adult; Amines; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Body Weight; Cyclohexa | 2005 |
Evaluation of the optimal preemptive dose of gabapentin for postoperative pain relief after lumbar diskectomy: a randomized, double-blind, placebo-controlled study.
Topics: Adult; Amines; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Body Weight; Cyclohexa | 2005 |
Evaluation of the optimal preemptive dose of gabapentin for postoperative pain relief after lumbar diskectomy: a randomized, double-blind, placebo-controlled study.
Topics: Adult; Amines; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Body Weight; Cyclohexa | 2005 |
Evaluation of the optimal preemptive dose of gabapentin for postoperative pain relief after lumbar diskectomy: a randomized, double-blind, placebo-controlled study.
Topics: Adult; Amines; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Body Weight; Cyclohexa | 2005 |
Evaluation of the optimal preemptive dose of gabapentin for postoperative pain relief after lumbar diskectomy: a randomized, double-blind, placebo-controlled study.
Topics: Adult; Amines; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Body Weight; Cyclohexa | 2005 |
Evaluation of the optimal preemptive dose of gabapentin for postoperative pain relief after lumbar diskectomy: a randomized, double-blind, placebo-controlled study.
Topics: Adult; Amines; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Body Weight; Cyclohexa | 2005 |
Evaluation of the optimal preemptive dose of gabapentin for postoperative pain relief after lumbar diskectomy: a randomized, double-blind, placebo-controlled study.
Topics: Adult; Amines; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Body Weight; Cyclohexa | 2005 |
Evaluation of the optimal preemptive dose of gabapentin for postoperative pain relief after lumbar diskectomy: a randomized, double-blind, placebo-controlled study.
Topics: Adult; Amines; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Body Weight; Cyclohexa | 2005 |
Evaluation of the optimal preemptive dose of gabapentin for postoperative pain relief after lumbar diskectomy: a randomized, double-blind, placebo-controlled study.
Topics: Adult; Amines; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Body Weight; Cyclohexa | 2005 |
Evaluation of the optimal preemptive dose of gabapentin for postoperative pain relief after lumbar diskectomy: a randomized, double-blind, placebo-controlled study.
Topics: Adult; Amines; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Body Weight; Cyclohexa | 2005 |
Evaluation of the optimal preemptive dose of gabapentin for postoperative pain relief after lumbar diskectomy: a randomized, double-blind, placebo-controlled study.
Topics: Adult; Amines; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Body Weight; Cyclohexa | 2005 |
Evaluation of the optimal preemptive dose of gabapentin for postoperative pain relief after lumbar diskectomy: a randomized, double-blind, placebo-controlled study.
Topics: Adult; Amines; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Body Weight; Cyclohexa | 2005 |
Evaluation of the optimal preemptive dose of gabapentin for postoperative pain relief after lumbar diskectomy: a randomized, double-blind, placebo-controlled study.
Topics: Adult; Amines; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Body Weight; Cyclohexa | 2005 |
Evaluation of the optimal preemptive dose of gabapentin for postoperative pain relief after lumbar diskectomy: a randomized, double-blind, placebo-controlled study.
Topics: Adult; Amines; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Body Weight; Cyclohexa | 2005 |
Evaluation of the optimal preemptive dose of gabapentin for postoperative pain relief after lumbar diskectomy: a randomized, double-blind, placebo-controlled study.
Topics: Adult; Amines; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Body Weight; Cyclohexa | 2005 |
Effects of application site and subject demographics on the pharmacokinetics of fentanyl HCl patient-controlled transdermal system (PCTS).
Topics: Administration, Cutaneous; Adolescent; Adult; Aging; Analgesics, Opioid; Area Under Curve; Body Weig | 2005 |
[High-dose thalamonal-rohypnol for premedication. A randomized double-blind study].
Topics: Adolescent; Adult; Aged; Anesthetics; Anxiety; Blood Pressure; Body Weight; Clinical Trials as Topic | 1984 |
Recovery following intravenous sedation during dental surgery performed under local anesthesia.
Topics: Adolescent; Adult; Anesthesia, Dental; Anesthesia, Local; Body Weight; Diazepam; Female; Fentanyl; H | 1980 |
Disposition of transdermally administered fentanyl in dogs.
Topics: Absorption; Administration, Cutaneous; Analgesics, Opioid; Animals; Body Weight; Cross-Over Studies; | 1996 |
Study of the safe threshold of apneic period in children during anesthesia induction.
Topics: Age Factors; Anesthesia, Intravenous; Anesthetics, Intravenous; Apnea; Body Height; Body Weight; Bra | 1996 |
Midazolam premedication increases sedation but does not prolong discharge times after brief outpatient general anesthesia for laparoscopic tubal sterilization.
Topics: Adult; Age Factors; Ambulatory Surgical Procedures; Analgesics, Opioid; Anesthesia Recovery Period; | 1997 |
Ondansetron versus metoclopramide in the treatment of postoperative nausea and vomiting.
Topics: Adolescent; Adult; Age Factors; Aged; Anesthesia Recovery Period; Anesthetics, Intravenous; Antiemet | 1997 |
Site of action of fentanyl in inhibiting the pituitary-adrenal response to surgery in man.
Topics: Arginine Vasopressin; Body Weight; Corticotropin-Releasing Hormone; Fallopian Tubes; Female; Fentany | 1990 |
[Relative potency of morphine, meperidine and fentanyl during anesthesia with nitrous oxide].
Topics: Adjuvants, Anesthesia; Adult; Aged; Anesthesia, Inhalation; Body Weight; Clinical Trials as Topic; D | 1972 |
59 other studies available for fentanyl and Body Weight
| Article | Year |
|---|---|
Pre- and Postnatal Maturation are Important for Fentanyl Exposure in Preterm and Term Newborns: A Pooled Population Pharmacokinetic Study.
Topics: Analgesics, Opioid; Birth Weight; Body Weight; Fentanyl; Gestational Age; Humans; Infant; Infant, Ne | 2022 |
Spinal anesthesia for surgery longer than 60 min in infants: experience from the first 2 years of a spinal anesthesia program.
Topics: Anesthesia, General; Anesthesia, Spinal; Body Weight; Bupivacaine; Clonidine; Dexmedetomidine; Fenta | 2018 |
Pharmacokinetics of fentanyl after intravenous administration in isoflurane-anesthetized red-tailed hawks (Buteo jamaicensis) and Hispaniolan Amazon parrots (Amazona ventralis).
Topics: Administration, Intravenous; Amazona; Anesthesia; Animals; Body Weight; Female; Fentanyl; Hawks; Inj | 2018 |
A predictive pharmacokinetic/pharmacodynamic model of fentanyl for analgesia/sedation in neonates based on a semi-physiologic approach.
Topics: Analgesics, Opioid; Body Weight; Fentanyl; Growth; Humans; Hypnotics and Sedatives; Infant, Newborn; | 2013 |
Thermal sensitivity across ages and during chronic fentanyl administration in rats.
Topics: Aging; Analgesics, Opioid; Animals; Body Weight; Chronic Pain; Data Interpretation, Statistical; Fen | 2014 |
Propofol and fentanyl take longer for induction of anesthesia in aortic regurgitation: a case-controlled prospective study.
Topics: Adult; Aged; Anesthesia, General; Anesthesia, Intravenous; Anesthetics, Intravenous; Aortic Valve In | 2014 |
The effect of benfotiamine on mu-opioid receptor mediated antinociception in experimental diabetes.
Topics: Analgesics; Analgesics, Opioid; Animals; Body Weight; Diabetes Mellitus, Experimental; Fentanyl; For | 2014 |
THE EFFECT OF OBESITY ON DOSE OF DEXMEDETOMIDINE WHEN ADMINISTERED WITH FENTANYL DURING POSTOPERATIVE MECHANICAL VENTILATION--RETROSPECTIVE.
Topics: Body Mass Index; Body Weight; Dexmedetomidine; Fentanyl; Humans; Obesity; Respiration, Artificial; R | 2015 |
Does intravenous induction dosing among patients undergoing gastrointestinal surgical procedures follow current recommendations: a study of contemporary practice.
Topics: Adult; Aged; Aged, 80 and over; Aging; Algorithms; Anesthesia, Intravenous; Anesthetics, Intravenous | 2016 |
Intranasal fentanyl paediatric clinical practice guidelines.
Topics: Administration, Intranasal; Body Weight; Child, Preschool; Emergency Medicine; Fentanyl; Humans; Inf | 2009 |
Effects of chronic fentanyl administration on physical performance of aged rats.
Topics: Aging; Analgesics, Opioid; Animals; Behavior, Animal; Body Composition; Body Weight; Drug Evaluation | 2011 |
Chronic psychosocial stress induces visceral hyperalgesia in mice.
Topics: Adrenal Glands; Analgesics, Opioid; Animals; Anxiety; Atropine; Body Weight; Chronic Disease; Colon; | 2012 |
Opioid analgesics in experimental sepsis: effects on physiological, biochemical, and haemodynamic parameters.
Topics: Analgesics, Opioid; Animals; Biochemical Phenomena; Body Temperature; Body Weight; Cardiovascular Sy | 2013 |
Average recovery time from a standardized intravenous sedation protocol and standardized discharge criteria in the general dental practice setting.
Topics: Adolescent; Adult; Aged; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, Intravenous; An | 2002 |
[Should the dosage of fentanyl be based on the body weight when the patient is obese? A proposal of the appropriate "pharmacokinetic body mass"].
Topics: Analgesics, Opioid; Anesthetics, Intravenous; Body Weight; Fentanyl; Humans; Obesity | 2004 |
Pharmacokinetic mass of fentanyl for postoperative analgesia in lean and obese patients.
Topics: Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Anthropometry; Body Weight; Dose-Response Relati | 2005 |
The impact of the opioids fentanyl and morphine on nociception and bone destruction in a murine model of bone cancer pain.
Topics: Analgesics, Opioid; Animals; Behavior, Animal; Body Weight; Bone and Bones; Bone Neoplasms; Femur; F | 2007 |
The use of patient-controlled epidural fentanyl in elderly patients.
Topics: Abdomen; Adult; Age Factors; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Body Weight; C | 2007 |
[Neuroanesthesiology in the child weighing less than 10 kilos: use of Alfatesine combined with a morphinomimetic].
Topics: Alfaxalone Alfadolone Mixture; Anesthetics; Body Weight; Child, Preschool; Drug Therapy, Combination | 1980 |
Further evidence validating adjuvant arthritis as an experimental model of chronic pain in the rat.
Topics: Animals; Arthritis; Arthritis, Experimental; Body Weight; Chronic Disease; Disease Models, Animal; D | 1982 |
Effects of fentanyl on respiratory pressure-volume relationship in supine anesthetized children.
Topics: Anesthesia, General; Body Weight; Child; Fentanyl; Humans; Lung Compliance; Lung Volume Measurements | 1981 |
Infusion model for fentanyl based on pharmacokinetic analysis.
Topics: Adult; Anesthesia, Intravenous; Body Weight; Drug Administration Schedule; Female; Fentanyl; Half-Li | 1980 |
[Anaesthesia by administration at a constant rate of fentanyl and methohexitone (300 patients). Clinical study (author's transl)].
Topics: Aging; Analgesia; Anesthesia, General; Body Weight; Bone and Bones; Female; Fentanyl; Humans; Male; | 1980 |
A multifactorial analysis to explain inadequate surgical analgesia after extradural block.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesia, Epidural; Anesthesia, Epidural; Anesthetics, | 1995 |
Effect of stress on oral fentanyl consumption in rats in an operant self-administration paradigm.
Topics: Animals; Body Weight; Conditioning, Operant; Drinking; Electroshock; Fentanyl; Male; Naloxone; Rats; | 1993 |
Spontaneous movement after injection of propofol.
Topics: Adult; Anesthetics, Intravenous; Asian People; Body Weight; Dose-Response Relationship, Drug; Female | 1996 |
Factors associated with hypotension and bradycardia after epidural blockade.
Topics: Adjuvants, Anesthesia; Adult; Aged; Analgesia, Epidural; Anesthesia, Epidural; Anesthetics, Local; B | 1996 |
Chronic cadmium exposure attenuates the conditioned reinforcing properties of morphine and fentanyl.
Topics: Animals; Body Weight; Cadmium; Conditioning, Psychological; Diet; Drug Synergism; Eating; Fentanyl; | 1997 |
Antagonism of atracurium-induced block in obese patients.
Topics: Adult; Anesthetics, Inhalation; Anesthetics, Intravenous; Atracurium; Body Mass Index; Body Weight; | 1998 |
The pharmacokinetics of vecuronium in male and female patients.
Topics: Adolescent; Adult; Anesthetics, Inhalation; Anesthetics, Intravenous; Area Under Curve; Blood Loss, | 1998 |
Craniotomy procedures are associated with less analgesic requirements than other surgical procedures.
Topics: Analgesics; Analgesics, Opioid; Anesthesia Recovery Period; Anesthetics, Intravenous; Body Weight; B | 1999 |
Craniotomy procedures are associated with less analgesic requirements than other surgical procedures.
Topics: Analgesics; Analgesics, Opioid; Anesthesia Recovery Period; Anesthetics, Intravenous; Body Weight; B | 1999 |
Craniotomy procedures are associated with less analgesic requirements than other surgical procedures.
Topics: Analgesics; Analgesics, Opioid; Anesthesia Recovery Period; Anesthetics, Intravenous; Body Weight; B | 1999 |
Craniotomy procedures are associated with less analgesic requirements than other surgical procedures.
Topics: Analgesics; Analgesics, Opioid; Anesthesia Recovery Period; Anesthetics, Intravenous; Body Weight; B | 1999 |
Is total body weight an appropriate predictor for propofol maintenance dose?
Topics: Anesthetics, Dissociative; Anesthetics, Intravenous; Body Height; Body Mass Index; Body Weight; Chro | 1999 |
Subcutaneous administration of fentanyl and midazolam to prevent withdrawal after prolonged sedation in children.
Topics: Analgesics, Opioid; Body Weight; Child; Child, Preschool; Conscious Sedation; Fentanyl; Humans; Hypn | 1999 |
Sedation and analgesia in adult patients: evaluation of a staged-dose system based on body weight for use in abdominal interventional radiology.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesia; Analgesics, Opioid; Body Weight; Conscious Se | 2000 |
Phenytoin, midazolam, and naloxone protect against fentanyl-induced brain damage in rats.
Topics: Analgesics, Opioid; Animals; Anticonvulsants; Blood Gas Analysis; Body Weight; Brain Diseases; Elect | 2000 |
Pharmacokinetics of transdermal fentanyl in the peri-operative period in young children.
Topics: Administration, Cutaneous; Age Factors; Analgesics, Opioid; Area Under Curve; Body Weight; Child, Pr | 2000 |
Anxiogenic-like effects of opiate withdrawal seen in the fear-potentiated startle test, an interdisciplinary probe for drug-related motivational states.
Topics: Acoustic Stimulation; Analgesics, Opioid; Animals; Anxiety; Behavior, Animal; Body Weight; Fear; Fen | 2001 |
Effects of adolescent nicotine exposure on opioid consumption and neuroendocrine responses in adult male and female rats.
Topics: Adrenocorticotropic Hormone; Aging; Analgesics, Opioid; Animals; Body Weight; Corticosterone; Drinki | 2001 |
Effects of agmatine on the escalation of intravenous cocaine and fentanyl self-administration in rats.
Topics: Agmatine; Analgesics, Opioid; Animals; Body Weight; Cocaine-Related Disorders; Conditioning, Operant | 2002 |
[An attempt to determine optimum dosage of fentanyl in neurolept analgesia (author's transl)].
Topics: Body Height; Body Surface Area; Body Weight; Dose-Response Relationship, Drug; Evaluation Studies as | 1979 |
Multinational evaluation of etomidate for anesthesia induction. Conclusions and consequences.
Topics: Adolescent; Adult; Age Factors; Aged; Blood Pressure; Body Weight; Child; Child, Preschool; Etomidat | 1978 |
[Review of 1,177 cases of premedication with thalamonal in pediatric anesthesia].
Topics: Adolescent; Anesthesia, Inhalation; Body Weight; Child; Child, Preschool; Droperidol; Drug Combinati | 1975 |
Apparent pA2 value of naltrexone is not changed in rats following continuous exposure to morphine or naloxone.
Topics: Analysis of Variance; Animals; Body Weight; Dose-Response Relationship, Drug; Drug Interactions; Fen | 1992 |
Parker and Radow test of drug withdrawal aversion: opposite effect in rats chronically infused with sufentanil or amphetamine.
Topics: Analgesics, Opioid; Animals; Body Weight; Choice Behavior; Dextroamphetamine; Fentanyl; Infusion Pum | 1990 |
Occurrence of sexual maturation in chronic opiate-treated female rats.
Topics: Animals; Body Weight; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fentan | 1991 |
Pharmacokinetics of alfentanil during and after a fixed rate infusion.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Alfentanil; Anesthetics; Body Weight; Femal | 1989 |
Comparison of analgesic requirements after liver transplantation and cholecystectomy.
Topics: Adult; Body Weight; Cholecystectomy; Female; Fentanyl; Humans; Kidney; Liver Transplantation; Male; | 1989 |
Long-term blockade of mu-opioid receptors suggests a role in control of ingestive behaviour, body weight and core temperature in the rat.
Topics: Animals; Benzomorphans; Body Temperature Regulation; Body Weight; Circadian Rhythm; Drinking Behavio | 1988 |
Intravenous anaesthesia with propofol and alfentanil. The influence of age and weight.
Topics: Adult; Age Factors; Aged; Alfentanil; Anesthesia, Intravenous; Anesthetics; Blood Pressure; Body Wei | 1986 |
Population pharmacokinetics of alfentanil: the average dose-plasma concentration relationship and interindividual variability in patients.
Topics: Adult; Alfentanil; Anesthesia, General; Body Weight; Female; Fentanyl; Humans; Kinetics; Male; Mathe | 1987 |
The pharmacokinetics of alfentanil in children.
Topics: Adolescent; Aging; Alfentanil; Anesthesia, Intravenous; Anesthetics; Body Weight; Child; Child, Pres | 1987 |
Reproductive and teratogenic effects of nitrous oxide, fentanyl and their combination in Sprague-Dawley rats.
Topics: Abnormalities, Drug-Induced; Animals; Body Weight; Drug Synergism; Female; Fentanyl; Nitrous Oxide; | 1987 |
Constitutional factors promoting development of atelectasis during anaesthesia.
Topics: Adult; Aged; Anesthesia, General; Body Constitution; Body Height; Body Weight; Female; Fentanyl; Hal | 1987 |
Neurolept anaesthesia using etomidate as the hypnotic agent.
Topics: Adolescent; Adult; Age Factors; Aged; Anesthesia Recovery Period; Anesthesia, Intravenous; Body Weig | 1986 |
Dose-time curves of droperidol and fentanyl in relation to body surface and weight in man.
Topics: Adult; Age Factors; Aged; Anesthesia, General; Benperidol; Body Surface Area; Body Weight; Dose-Resp | 1972 |
Innovar as preoperative medication for cataract surgery.
Topics: Aged; Body Height; Body Weight; Cataract Extraction; Droperidol; Drug Combinations; Fentanyl; Humans | 1973 |
Awareness during anaesthesia: a comparison of anaesthesia with nitrous oxide-oxygen and nitrous oxide-oxygen with innovar.
Topics: Adult; Aged; Anesthesia; Body Weight; Cognition; Consciousness; Dreams; Droperidol; Female; Fentanyl | 1973 |
Problems for the anaesthetist in the care of the obese patient.
Topics: Anesthesia, General; Blood Pressure Determination; Body Height; Body Weight; Fentanyl; Halothane; Hu | 1968 |
[Liver circulation, cardiac output and other circulatory measurements under the effect of various anesthetics in dogs].
Topics: Anesthesia, Inhalation; Anesthesia, Intravenous; Animals; Benperidol; Blood Pressure; Blood Volume; | 1969 |