fentanyl has been researched along with Benign Supratentorial Neoplasms in 20 studies
Fentanyl: A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078)
fentanyl : A monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of N-phenyl-1-(2-phenylethyl)piperidin-4-amine with propanoic acid.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This prospective, randomized, placebo-controlled, double-blinded study was designed to evaluate the efficacy of tropisetron in preventing postoperative nausea and vomiting after elective supratentorial craniotomy in adult patients." | 9.10 | Randomized, double-blinded comparison of tropisetron and placebo for prevention of postoperative nausea and vomiting after supratentorial craniotomy. ( Boyaci, A; Dogru, K; Güler, G; Kurtsoy, A; Madenoglu, H; Yildiz, K, 2003) |
| "The study indicates that before as well as during hyperventilation, subdural ICP and AVDo2 are lower and CPP higher in propofol-anesthetized patients compared with patients anesthetized with isoflurane or sevoflurane." | 5.10 | Intracranial pressure and cerebral hemodynamic in patients with cerebral tumors: a randomized prospective study of patients subjected to craniotomy in propofol-fentanyl, isoflurane-fentanyl, or sevoflurane-fentanyl anesthesia. ( Cold, GE; Hauerberg, J; Holst, P; Landsfeldt, U; Mau, S; Olsen, KS; Petersen, CB; Petersen, KD, 2003) |
| "This prospective, randomized, placebo-controlled, double-blinded study was designed to evaluate the efficacy of tropisetron in preventing postoperative nausea and vomiting after elective supratentorial craniotomy in adult patients." | 5.10 | Randomized, double-blinded comparison of tropisetron and placebo for prevention of postoperative nausea and vomiting after supratentorial craniotomy. ( Boyaci, A; Dogru, K; Güler, G; Kurtsoy, A; Madenoglu, H; Yildiz, K, 2003) |
| "The study group included patients with supratentorial tumors undergoing craniotomy, and the control group consisted of patients undergoing spinal surgeries." | 2.77 | Fentanyl co-administration decreases the induction dose requirement of propofol in patients with supratentorial tumors and not in patients with spinal lesions. ( Bansal, S; Ramesh, VJ; Umamaheswara Rao, GS, 2012) |
| "Systemic hypertension is a major drawback associated with fast tracking, which may predispose to formation of intracranial hematoma." | 2.73 | Planning for early emergence in neurosurgical patients: a randomized prospective trial of low-dose anesthetics. ( Bhagat, H; Bithal, PK; Chouhan, RS; Dash, HH; Pandia, MP, 2008) |
| "Remifentanil hydrochloride is an ultra-short acting m-opioid receptor agonist." | 2.72 | Remifentanil vs fentanyl with a target controlled propofol infusion in patients undergoing craniotomy for supratentorial lesions. ( Ciritella, P; De Vivo, P; Del Gaudio, A; Lauta, E; Mastronardi, P; Perrotta, F; Puopolo, M, 2006) |
| "Remifentanil is a suitable alternative to fentanyl in supratentorial craniotomy." | 2.71 | Remifentanil with morphine transitional analgesia shortens neurological recovery compared to fentanyl for supratentorial craniotomy. ( Chung, F; Gelb, AW; Manninen, PH; McTaggart-Cowan, RM; Ringaert, K; Salevsky, F; Wong, T, 2003) |
| "Sevoflurane is a cerebral vasodilator in patients with cerebral tumours." | 2.69 | Effects of sevoflurane on intracranial pressure, cerebral blood flow and cerebral metabolism. A dose-response study in patients subjected to craniotomy for cerebral tumours. ( Bundgaard, H; Cold, GE; Jensen, KA; Landsfeldt, U; Larsen, KM; Nielsen, E; von Oettingen, G, 1998) |
| "Remifentanil hydrochloride is an ultra-short-acting, esterase-metabolized mu-opioid receptor agonist." | 2.68 | Comparison of remifentanil and fentanyl in patients undergoing craniotomy for supratentorial space-occupying lesions. ( Baker, KZ; Borel, CO; Fogarty-Mack, P; Guy, J; Hindman, BJ; Kirchner, J; Maktabi, M; McAllister, A; Ostapkovich, N; Roland, C; Sokoll, MD; Todd, MM; Warner, DS; Yancy, V; Young, WL, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 9 (45.00) | 18.2507 |
| 2000's | 8 (40.00) | 29.6817 |
| 2010's | 3 (15.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lin, N | 1 |
| Han, R | 1 |
| Zhou, J | 1 |
| Gelb, AW | 2 |
| Bhagat, H | 1 |
| Dash, HH | 1 |
| Bithal, PK | 1 |
| Chouhan, RS | 1 |
| Pandia, MP | 1 |
| Bansal, S | 1 |
| Ramesh, VJ | 1 |
| Umamaheswara Rao, GS | 1 |
| Chowdhury, T | 1 |
| Cappellani, RB | 1 |
| Petersen, KD | 1 |
| Landsfeldt, U | 3 |
| Cold, GE | 3 |
| Petersen, CB | 1 |
| Mau, S | 1 |
| Hauerberg, J | 1 |
| Holst, P | 1 |
| Olsen, KS | 1 |
| Madenoglu, H | 1 |
| Yildiz, K | 1 |
| Dogru, K | 1 |
| Kurtsoy, A | 1 |
| Güler, G | 1 |
| Boyaci, A | 1 |
| Salevsky, F | 1 |
| Chung, F | 1 |
| Ringaert, K | 1 |
| McTaggart-Cowan, RM | 1 |
| Wong, T | 1 |
| Manninen, PH | 1 |
| Tsai, HJ | 1 |
| Tsou, KF | 1 |
| Liu, HT | 1 |
| Chu, CC | 1 |
| Tsao, CM | 1 |
| Tsou, MY | 1 |
| Tsai, SK | 1 |
| Magni, G | 1 |
| Baisi, F | 1 |
| La Rosa, I | 1 |
| Imperiale, C | 1 |
| Fabbrini, V | 1 |
| Pennacchiotti, ML | 1 |
| Rosa, G | 1 |
| Del Gaudio, A | 1 |
| Ciritella, P | 1 |
| Perrotta, F | 1 |
| Puopolo, M | 1 |
| Lauta, E | 1 |
| Mastronardi, P | 1 |
| De Vivo, P | 1 |
| Bauer, C | 1 |
| Kreuer, S | 1 |
| Ketter, R | 1 |
| Grundmann, U | 1 |
| Wilhelm, W | 1 |
| Todd, MM | 3 |
| Warner, DS | 3 |
| Sokoll, MD | 3 |
| Maktabi, MA | 1 |
| Hindman, BJ | 2 |
| Scamman, FL | 1 |
| Kirschner, J | 1 |
| Jamali, S | 1 |
| Ravussin, P | 1 |
| Archer, D | 1 |
| Goutallier, D | 1 |
| Parker, F | 1 |
| Ecoffey, C | 1 |
| Guy, J | 1 |
| Baker, KZ | 1 |
| Borel, CO | 1 |
| Maktabi, M | 1 |
| Ostapkovich, N | 1 |
| Kirchner, J | 1 |
| Fogarty-Mack, P | 1 |
| Yancy, V | 1 |
| McAllister, A | 1 |
| Roland, C | 1 |
| Young, WL | 1 |
| Bundgaard, H | 2 |
| von Oettingen, G | 2 |
| Larsen, KM | 2 |
| Jensen, KA | 2 |
| Nielsen, E | 1 |
| Hogue, S | 1 |
| Reese, PR | 1 |
| Munshi, O | 1 |
| Young, T | 1 |
| Mutch, WA | 1 |
| Ringaert, KR | 1 |
| Ewert, FJ | 1 |
| White, IW | 1 |
| Donen, N | 1 |
| Hudson, RJ | 1 |
| From, RP | 1 |
| Jung, R | 1 |
| Shah, N | 1 |
| Reinsel, R | 1 |
| Marx, W | 1 |
| Marshall, W | 1 |
| Galicich, J | 1 |
| Bedford, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Influence of Vasopressors on Brain Oxygenation and Microcirculation in Anesthetized Patients With Cerebral Tumors[NCT02713087] | Phase 4 | 48 participants (Actual) | Interventional | 2015-09-30 | Completed | ||
| Cognitive Functions After TIVA With Dexmedetomidine[NCT02631135] | Phase 4 | 40 participants (Actual) | Interventional | 2008-01-31 | Completed | ||
| Anesthesiological Strategies in Elective Craniotomy: Randomized, Equivalence, Open Trial[NCT00741351] | Phase 3 | 411 participants (Actual) | Interventional | 2007-12-31 | Completed | ||
| Anaesthesia for Supratentorial Tumor Resection : a Double-blind Comparison of Target Plasma Concentration of Propofol-remifentanil and Sevoflurane-sufentanil[NCT00389883] | Phase 3 | 69 participants (Actual) | Interventional | 2006-11-30 | Completed | ||
| The Effect of Furosemide Versus Placebo on Brain Relaxation and Incidence of Significant Intravascular Volume Depletion in Human Subjects Receiving Mannitol[NCT01054404] | 23 participants (Actual) | Interventional | 2010-02-28 | Terminated (stopped due to Concern for volume depletion and electrolyte abnormalities in furosemide arm.) | |||
| Clinical Effectiveness of Hypertonic Sodium Lactate Infusion for Intraoperative Brain Relaxation in Patients Undergoing Scheduled Craniotomy for Supratentorial Brain Tumor Resection: Study Protocol of a Single Center Double-blind Randomized Controlled Pha[NCT04488874] | Phase 3 | 50 participants (Actual) | Interventional | 2020-09-29 | Completed | ||
| Comparison of Dexmedetomidine and Propofol-Remifentanil Conscious Sedation for Awake Craniotomy for Tumor Surgery: a Randomized Controlled Trial[NCT01545297] | 50 participants (Actual) | Interventional | 2012-11-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
"Rating of brain relaxation will be on a 4-point scale:~0 = brain very relaxed under dura, acceptable~= brain adequately relaxed under dura, acceptable~= brain slightly tense under dura, acceptable~= brain very tense under bulging dura, unacceptable" (NCT01054404)
Timeframe: just prior to dural opening for each subject
| Intervention | units on a scale 0-3 (Mean) |
|---|---|
| Furosemide | 1.5 |
| Placebo | 1.3 |
18 trials available for fentanyl and Benign Supratentorial Neoplasms
| Article | Year |
|---|---|
Mild Sedation Exacerbates or Unmasks Focal Neurologic Dysfunction in Neurosurgical Patients with Supratentorial Brain Mass Lesions in a Drug-specific Manner.
Topics: Adult; Dexmedetomidine; Female; Fentanyl; Follow-Up Studies; Humans; Hypnotics and Sedatives; Male; | 2016 |
Planning for early emergence in neurosurgical patients: a randomized prospective trial of low-dose anesthetics.
Topics: Adult; Anesthesia Recovery Period; Anesthetics, Inhalation; Anesthetics, Intravenous; Blood Pressure | 2008 |
Fentanyl co-administration decreases the induction dose requirement of propofol in patients with supratentorial tumors and not in patients with spinal lesions.
Topics: Adult; Anesthesia, Intravenous; Anesthetics, Intravenous; Craniotomy; Female; Fentanyl; Glasgow Coma | 2012 |
Intracranial pressure and cerebral hemodynamic in patients with cerebral tumors: a randomized prospective study of patients subjected to craniotomy in propofol-fentanyl, isoflurane-fentanyl, or sevoflurane-fentanyl anesthesia.
Topics: Adolescent; Adult; Aged; Anesthesia, General; Anesthesia, Inhalation; Anesthetics, Inhalation; Anest | 2003 |
Randomized, double-blinded comparison of tropisetron and placebo for prevention of postoperative nausea and vomiting after supratentorial craniotomy.
Topics: Adolescent; Adult; Aged; Analgesics, Opioid; Antiemetics; Craniotomy; Double-Blind Method; Female; F | 2003 |
Remifentanil with morphine transitional analgesia shortens neurological recovery compared to fentanyl for supratentorial craniotomy.
Topics: Adult; Analgesia; Analgesics, Opioid; Anesthesia Recovery Period; Brain; Canada; Craniotomy; Double- | 2003 |
Comparison of the recovery from isoflurane anesthesia with or without fentanyl infusion in patients undergoing elective supratentorial craniotomy.
Topics: Anesthesia Recovery Period; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; | 2003 |
No difference in emergence time and early cognitive function between sevoflurane-fentanyl and propofol-remifentanil in patients undergoing craniotomy for supratentorial intracranial surgery.
Topics: Adolescent; Adult; Aged; Anesthesia Recovery Period; Anesthesia, Inhalation; Anesthesia, Intravenous | 2005 |
No difference in emergence time and early cognitive function between sevoflurane-fentanyl and propofol-remifentanil in patients undergoing craniotomy for supratentorial intracranial surgery.
Topics: Adolescent; Adult; Aged; Anesthesia Recovery Period; Anesthesia, Inhalation; Anesthesia, Intravenous | 2005 |
No difference in emergence time and early cognitive function between sevoflurane-fentanyl and propofol-remifentanil in patients undergoing craniotomy for supratentorial intracranial surgery.
Topics: Adolescent; Adult; Aged; Anesthesia Recovery Period; Anesthesia, Inhalation; Anesthesia, Intravenous | 2005 |
No difference in emergence time and early cognitive function between sevoflurane-fentanyl and propofol-remifentanil in patients undergoing craniotomy for supratentorial intracranial surgery.
Topics: Adolescent; Adult; Aged; Anesthesia Recovery Period; Anesthesia, Inhalation; Anesthesia, Intravenous | 2005 |
Remifentanil vs fentanyl with a target controlled propofol infusion in patients undergoing craniotomy for supratentorial lesions.
Topics: Adult; Aged; Anesthesia Recovery Period; Anesthesia, Intravenous; Anesthetics, Intravenous; Cranioto | 2006 |
A prospective, comparative trial of three anesthetics for elective supratentorial craniotomy. Propofol/fentanyl, isoflurane/nitrous oxide, and fentanyl/nitrous oxide.
Topics: Adult; Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Craniotomy; Female; Fentanyl; Glioma; | 1993 |
A prospective, comparative trial of three anesthetics for elective supratentorial craniotomy. Propofol/fentanyl, isoflurane/nitrous oxide, and fentanyl/nitrous oxide.
Topics: Adult; Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Craniotomy; Female; Fentanyl; Glioma; | 1993 |
A prospective, comparative trial of three anesthetics for elective supratentorial craniotomy. Propofol/fentanyl, isoflurane/nitrous oxide, and fentanyl/nitrous oxide.
Topics: Adult; Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Craniotomy; Female; Fentanyl; Glioma; | 1993 |
A prospective, comparative trial of three anesthetics for elective supratentorial craniotomy. Propofol/fentanyl, isoflurane/nitrous oxide, and fentanyl/nitrous oxide.
Topics: Adult; Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Craniotomy; Female; Fentanyl; Glioma; | 1993 |
A prospective, comparative trial of three anesthetics for elective supratentorial craniotomy. Propofol/fentanyl, isoflurane/nitrous oxide, and fentanyl/nitrous oxide.
Topics: Adult; Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Craniotomy; Female; Fentanyl; Glioma; | 1993 |
A prospective, comparative trial of three anesthetics for elective supratentorial craniotomy. Propofol/fentanyl, isoflurane/nitrous oxide, and fentanyl/nitrous oxide.
Topics: Adult; Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Craniotomy; Female; Fentanyl; Glioma; | 1993 |
A prospective, comparative trial of three anesthetics for elective supratentorial craniotomy. Propofol/fentanyl, isoflurane/nitrous oxide, and fentanyl/nitrous oxide.
Topics: Adult; Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Craniotomy; Female; Fentanyl; Glioma; | 1993 |
A prospective, comparative trial of three anesthetics for elective supratentorial craniotomy. Propofol/fentanyl, isoflurane/nitrous oxide, and fentanyl/nitrous oxide.
Topics: Adult; Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Craniotomy; Female; Fentanyl; Glioma; | 1993 |
A prospective, comparative trial of three anesthetics for elective supratentorial craniotomy. Propofol/fentanyl, isoflurane/nitrous oxide, and fentanyl/nitrous oxide.
Topics: Adult; Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Craniotomy; Female; Fentanyl; Glioma; | 1993 |
A prospective, comparative trial of three anesthetics for elective supratentorial craniotomy. Propofol/fentanyl, isoflurane/nitrous oxide, and fentanyl/nitrous oxide.
Topics: Adult; Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Craniotomy; Female; Fentanyl; Glioma; | 1993 |
A prospective, comparative trial of three anesthetics for elective supratentorial craniotomy. Propofol/fentanyl, isoflurane/nitrous oxide, and fentanyl/nitrous oxide.
Topics: Adult; Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Craniotomy; Female; Fentanyl; Glioma; | 1993 |
A prospective, comparative trial of three anesthetics for elective supratentorial craniotomy. Propofol/fentanyl, isoflurane/nitrous oxide, and fentanyl/nitrous oxide.
Topics: Adult; Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Craniotomy; Female; Fentanyl; Glioma; | 1993 |
A prospective, comparative trial of three anesthetics for elective supratentorial craniotomy. Propofol/fentanyl, isoflurane/nitrous oxide, and fentanyl/nitrous oxide.
Topics: Adult; Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Craniotomy; Female; Fentanyl; Glioma; | 1993 |
A prospective, comparative trial of three anesthetics for elective supratentorial craniotomy. Propofol/fentanyl, isoflurane/nitrous oxide, and fentanyl/nitrous oxide.
Topics: Adult; Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Craniotomy; Female; Fentanyl; Glioma; | 1993 |
A prospective, comparative trial of three anesthetics for elective supratentorial craniotomy. Propofol/fentanyl, isoflurane/nitrous oxide, and fentanyl/nitrous oxide.
Topics: Adult; Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Craniotomy; Female; Fentanyl; Glioma; | 1993 |
A prospective, comparative trial of three anesthetics for elective supratentorial craniotomy. Propofol/fentanyl, isoflurane/nitrous oxide, and fentanyl/nitrous oxide.
Topics: Adult; Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Craniotomy; Female; Fentanyl; Glioma; | 1993 |
The effects of bolus administration of opioids on cerebrospinal fluid pressure in patients with supratentorial lesions.
Topics: Adult; Aged; Anesthetics, Inhalation; Anti-Arrhythmia Agents; Atropine; Blood Pressure; Bradycardia; | 1996 |
Comparison of remifentanil and fentanyl in patients undergoing craniotomy for supratentorial space-occupying lesions.
Topics: Adult; Anesthesia, General; Anesthetics, Intravenous; Blood Pressure; Craniotomy; Double-Blind Metho | 1997 |
Effects of sevoflurane on intracranial pressure, cerebral blood flow and cerebral metabolism. A dose-response study in patients subjected to craniotomy for cerebral tumours.
Topics: Adult; Aged; Anesthetics, Combined; Anesthetics, Inhalation; Blood Pressure; Brain; Carbon Dioxide; | 1998 |
ICP during anaesthesia with sevoflurane: a dose-response study. Effect of hypocapnia.
Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Brain; Carbon Dioxide; Dose-Response Relationship, | 1998 |
Cost analysis of remifentanil and fentanyl for neurosurgical anesthesia.
Topics: Analgesics, Opioid; Anesthetics, Intravenous; Craniotomy; Double-Blind Method; Fentanyl; Hospital Co | 1999 |
Continuous opioid infusions for neurosurgical procedures: a double-blind comparison of alfentanil and fentanyl.
Topics: Adult; Aged; Alfentanil; Anesthesia Recovery Period; Anesthesia, Intravenous; Blood Pressure; Consci | 1991 |
Anesthesia for craniotomy: a double-blind comparison of alfentanil, fentanyl, and sufentanil.
Topics: Adult; Alfentanil; Analgesics, Opioid; Anesthesia; Blood Pressure; Craniotomy; Double-Blind Method; | 1990 |
Cerebrospinal fluid pressure in patients with brain tumors: impact of fentanyl versus alfentanil during nitrous oxide-oxygen anesthesia.
Topics: Adult; Alfentanil; Anesthesia, Inhalation; Blood Pressure; Carbon Dioxide; Cerebrospinal Fluid Press | 1990 |
2 other studies available for fentanyl and Benign Supratentorial Neoplasms
| Article | Year |
|---|---|
Role of fentanyl in supratentorial tumor: can it change the requirement of propofol?
Topics: Anesthesia, Intravenous; Anesthetics, Intravenous; Female; Fentanyl; Humans; Male; Propofol; Spinal | 2013 |
[Remifentanil-propofol versus fentanyl-midazolam combinations for intracranial surgery: influence of anaesthesia technique and intensive sedation on ventilation times and duration of stay in the ICU].
Topics: Anesthetics, Intravenous; Conscious Sedation; Critical Care; Databases, Factual; Fentanyl; Length of | 2007 |