fentanyl has been researched along with Back Pain in 31 studies
Fentanyl: A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078)
fentanyl : A monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of N-phenyl-1-(2-phenylethyl)piperidin-4-amine with propanoic acid.
Back Pain: Acute or chronic pain located in the posterior regions of the THORAX; LUMBOSACRAL REGION; or the adjacent regions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chloroprocaine has been associated with severe back pain after epidural anesthesia." | 9.07 | Back pain after epidural anesthesia with chloroprocaine. ( Kao, TC; Stevens, RA; Urmey, WF; Urquhart, BL, 1993) |
| "TIDD using a low-dose fentanyl admixture with bupivacaine in patients with postlaminectomy syndrome and refractory chronic low back pain results in similar pain relief to TIDD with hydromorphone and bupivacaine." | 7.96 | Comparative Effectiveness of Targeted Intrathecal Drug Delivery Using a Combination of Bupivacaine with Either Low-Dose Fentanyl or Hydromorphone in Chronic Back Pain Patients with Lumbar Postlaminectomy Syndrome. ( Ade, T; DeLozier, SJ; Hayek, SM; Janes, JL; Mohan, M; Roh, J; Sharma, G, 2020) |
| " Although this article focuses on serotonin syndrome as a result of an adverse interaction of selective serotonin reuptake inhibitors (SSRI) and fentanyl, it is important for not only anesthesia professionals, but all clinicians--such as those in emergency medicine and critical care--to be aware of this syndrome and its management." | 7.80 | Serotonin syndrome: fentanyl and selective serotonin reuptake inhibitor interactions. ( Greenier, E; Lukyanova, V; Reede, L, 2014) |
| "1 micrograms/kg fentanyl in low back pain patients reduced both sensory intensity and unpleasantness visual analogue scale (VAS) responses to experimental pain evoked by graded 5-sec nociceptive temperature stimuli (45-51 degrees C) as well as VAS-sensory and VAS-affective responses to clinical pain." | 7.67 | A simultaneous comparison of fentanyl's analgesic effects on experimental and clinical pain. ( Harkins, SW; Price, C; Price, DD; Rafii, A, 1986) |
| "Addition of dexamethasone to local lidocaine infiltration effectively decreases the incidence and severity of back pain after combined spinal-epidural anesthesia implemented for gynecological surgery." | 5.20 | Dexamethasone added to local lidocaine for infiltration along the spinal-epidural needle pathway decreases incidence and severity of backache after gynecological surgery. ( Cui, GX; Gao, W; Ren, Y, 2015) |
| "Chloroprocaine has been associated with severe back pain after epidural anesthesia." | 5.07 | Back pain after epidural anesthesia with chloroprocaine. ( Kao, TC; Stevens, RA; Urmey, WF; Urquhart, BL, 1993) |
| " Demographic data, visual analog scale (VAS) and Quebec Back Pain Disability Scale (QBPDS) scores, mean arterial pressure (MAP) and heart rate (HR), total dosage of fentanyl, satisfaction rate of anesthesia and complications were collected at different timepoints." | 4.31 | Effect of intradiscal local anesthetic injection on intraoperative pain during percutaneous transforaminal endoscopic discectomy: A retrospective study. ( Duan, L; Kang, JY; Zhang, JH; Zhang, JY; Zhou, HC, 2023) |
| "TIDD using a low-dose fentanyl admixture with bupivacaine in patients with postlaminectomy syndrome and refractory chronic low back pain results in similar pain relief to TIDD with hydromorphone and bupivacaine." | 3.96 | Comparative Effectiveness of Targeted Intrathecal Drug Delivery Using a Combination of Bupivacaine with Either Low-Dose Fentanyl or Hydromorphone in Chronic Back Pain Patients with Lumbar Postlaminectomy Syndrome. ( Ade, T; DeLozier, SJ; Hayek, SM; Janes, JL; Mohan, M; Roh, J; Sharma, G, 2020) |
| " The most common ER opioids prescribed were oxycodone (26%) and fentanyl (23%), and the most common noncancer pain diagnoses were back pain (65%) and arthritis (48%)." | 3.96 | Medical Use of Long-term Extended-release Opioid Analgesics in Commercially Insured Adults in the United States. ( Dasgupta, N; Jonsson Funk, M; Young, JC, 2020) |
| " Although this article focuses on serotonin syndrome as a result of an adverse interaction of selective serotonin reuptake inhibitors (SSRI) and fentanyl, it is important for not only anesthesia professionals, but all clinicians--such as those in emergency medicine and critical care--to be aware of this syndrome and its management." | 3.80 | Serotonin syndrome: fentanyl and selective serotonin reuptake inhibitor interactions. ( Greenier, E; Lukyanova, V; Reede, L, 2014) |
| "The authors treated 9 patients receiving intradiscal electrothermal therapy who were unable to tolerate the latter portion of their heating protocol secondary to axial low back pain despite high doses of opioids, with low dose ketamine." | 3.72 | Sedation with ketamine during intradiscal electrothermal therapy. ( Cohen, SP; Larkin, T, 2004) |
| "1 micrograms/kg fentanyl in low back pain patients reduced both sensory intensity and unpleasantness visual analogue scale (VAS) responses to experimental pain evoked by graded 5-sec nociceptive temperature stimuli (45-51 degrees C) as well as VAS-sensory and VAS-affective responses to clinical pain." | 3.67 | A simultaneous comparison of fentanyl's analgesic effects on experimental and clinical pain. ( Harkins, SW; Price, C; Price, DD; Rafii, A, 1986) |
| "Spinal epidural lipomatosis is a rare condition of adipose tissue hypertrophy in the epidural space." | 1.38 | Epidural lipomatosis causing new debilitating back pain in a patient with human immunodeficiency virus on highly active antiretroviral therapy. ( Billings, F; Hoyt, MR, 2012) |
| "Fentanyl 20 micrograms was added for procedures anticipated to last longer than 45 minutes (but less than 90 min)." | 1.30 | Procaine spinal anesthesia: a pilot study of the incidence of transient neurologic symptoms. ( Alexander, GD; Axelrod, EH; Brown, M; Schork, MA, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (12.90) | 18.7374 |
| 1990's | 5 (16.13) | 18.2507 |
| 2000's | 9 (29.03) | 29.6817 |
| 2010's | 10 (32.26) | 24.3611 |
| 2020's | 3 (9.68) | 2.80 |
| Authors | Studies |
|---|---|
| Duan, L | 1 |
| Zhang, JY | 1 |
| Zhang, JH | 1 |
| Kang, JY | 1 |
| Zhou, HC | 1 |
| Ade, T | 1 |
| Roh, J | 1 |
| Sharma, G | 1 |
| Mohan, M | 1 |
| DeLozier, SJ | 1 |
| Janes, JL | 1 |
| Hayek, SM | 1 |
| Young, JC | 1 |
| Jonsson Funk, M | 1 |
| Dasgupta, N | 1 |
| Martikainen, IK | 2 |
| Peciña, M | 2 |
| Love, TM | 2 |
| Nuechterlein, EB | 2 |
| Cummiford, CM | 2 |
| Green, CR | 2 |
| Harris, RE | 1 |
| Stohler, CS | 2 |
| Zubieta, JK | 2 |
| Gao, W | 1 |
| Ren, Y | 1 |
| Cui, GX | 1 |
| Greenier, E | 1 |
| Lukyanova, V | 1 |
| Reede, L | 1 |
| Naik, BI | 1 |
| Nemergut, EC | 1 |
| Kazemi, A | 1 |
| Fernández, L | 1 |
| Cederholm, SK | 1 |
| McMurry, TL | 1 |
| Durieux, ME | 1 |
| Trist, AJ | 1 |
| Sahota, H | 1 |
| Williams, L | 1 |
| Gross, DP | 1 |
| Bhambhani, Y | 1 |
| Haykowsky, MJ | 1 |
| Rashiq, S | 1 |
| Williams, BS | 1 |
| Wong, D | 1 |
| Amin, S | 1 |
| Billings, F | 1 |
| Hoyt, MR | 1 |
| Hannon, B | 1 |
| Zimmermann, C | 1 |
| Bryson, JR | 1 |
| Ringe, JD | 1 |
| Faber, H | 1 |
| Bock, O | 1 |
| Valentine, S | 1 |
| Felsenberg, D | 1 |
| Pfeifer, M | 1 |
| Minne, HW | 1 |
| Schwalen, S | 1 |
| Cohen, SP | 1 |
| Larkin, T | 1 |
| Davies, AN | 1 |
| Vriens, J | 1 |
| Manchikanti, L | 1 |
| Manchikanti, KN | 1 |
| Manchukonda, R | 1 |
| Pampati, V | 1 |
| Cash, KA | 1 |
| D'Arcy, Y | 1 |
| Rees, SG | 1 |
| Collis, RE | 1 |
| Davis, MP | 1 |
| Shaiova, LA | 1 |
| Angst, MS | 1 |
| McQuay, HJ | 1 |
| Bullingham, RE | 1 |
| Evans, PJ | 1 |
| Lloyd, JW | 1 |
| Moore, RA | 1 |
| Hannallah, M | 1 |
| Stevens, RA | 1 |
| Urmey, WF | 1 |
| Urquhart, BL | 1 |
| Kao, TC | 1 |
| Axelrod, EH | 1 |
| Alexander, GD | 1 |
| Brown, M | 1 |
| Schork, MA | 1 |
| Sigg, TR | 1 |
| Leikin, JB | 1 |
| Boucher, C | 1 |
| Girard, M | 1 |
| Drolet, P | 1 |
| Grenier, Y | 1 |
| Bergeron, L | 1 |
| Le Truong, HH | 1 |
| Hunt, TM | 1 |
| Plantevin, OM | 1 |
| Gilbert, JR | 1 |
| Iudel'son, IaB | 1 |
| Malkina, DN | 1 |
| Vas'kin, VZ | 1 |
| Price, DD | 1 |
| Harkins, SW | 1 |
| Rafii, A | 1 |
| Price, C | 1 |
| Cherry, DA | 1 |
| Gourlay, GK | 1 |
| McLachlan, M | 1 |
| Cousins, MJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Endogenous Opioid Systems and Symptom Change in Fibromyalgia[NCT02866461] | 0 participants (Actual) | Observational | 2021-11-30 | Withdrawn (stopped due to It was not possible to conduct this study at the University of Utah due to the inability of the PET research facility to synthesize the radiotracer central to this project. Project was transferred to another institution.) | |||
| The Role of Endogenous Opioids in Mindfulness-based Chronic Pain Relief[NCT04034004] | Early Phase 1 | 88 participants (Actual) | Interventional | 2021-01-01 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
(NCT04034004)
Timeframe: Delivered after completion of each of the 4 meditation intervention sessions. Up to 8 weeks.
| Intervention | units on a scale (Mean) | |||
|---|---|---|---|---|
| intervention 1 effectiveness | intervention 2 effectiveness | intervention 3 effectiveness | intervention 4 effectiveness | |
| Mindfulness Meditation | 4.83 | 4.05 | 4.21 | 4.51 |
| Non-mindfulness Meditation | 5.13 | 5.17 | 5.21 | 5.40 |
Pain severity and interference: impact of pain on daily function, location of pain, pain medications and amount of pain relief in the past 24 hours or the past week. Higher scores indicate higher chronic pain. BPI severity and interference scales are used and collected before and after each intervention. Higher BPI severity indicate higher chronic pain severity. Higher BPI interference scores indicate higher chronic pain interference.The scoring scale for severity and interference range from 0 - 10, respectively. (NCT04034004)
Timeframe: Administered at the baseline, post-intervention session 6 and post-intervention session 7. Outcome measurements will compare in BPI severity and interference from baseline to session 7.
| Intervention | units on a scale (Mean) | |||
|---|---|---|---|---|
| baseline BPI severity | session 7 BPI severity | baseline BPI interference | session 7 BPI interference | |
| Mindfulness Meditation | 4.47 | 3.94 | 4.40 | 3.38 |
| Non-mindfulness Meditation | 5.22 | 5.15 | 5.17 | 4.57 |
This is a 13-item questionnaire with 3 subscales assessing rumination, magnification, and helplessness in patients. A numeric value between 0 (not at all) and 4 (all the time) is provided in response to each statement. Scores on this assessment range from 0 to 52, with higher values reflecting more salient impacts of pain on one's day to day experience. The total range is from 0 - 52. (NCT04034004)
Timeframe: The Pain Catastrophizing Scale was administered at the baseline, post-intervention session 6 and session 7. Outcome measurements will compare change in Pain Catastrophizing Scale from baseline to session 7.
| Intervention | units on a scale (Mean) | |
|---|---|---|
| Baseline PCS | Session 7 PCS | |
| Mindfulness Meditation | 18.57 | 15.33 |
| Non-mindfulness Meditation | 20.83 | 18.48 |
"Numerical pain ratings (NRS) will be assessed while lying on the back and in response to the straight leg raise test (SLR). Pain ratings will be collected during SLR 1 and SLR 2 in the baseline, saline and naloxone sessions, respectively. The 11 point scan will include a minimum rating of 0 which is characterized as no pain whereas the maximum (10) is labeled as most intense imaginable. Higher numbers correspond to higher pain." (NCT04034004)
Timeframe: Pain ratings were collected while lying supine and in response to the straight leg raise test. Collected twice, once in the first half and one in the second half of the baseline, saline infusion and naloxone infusion sessions. Up to 8 weeks total.
| Intervention | units on a scale (Mean) | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| baseline session: supine 1 | baseline session: straight leg raise test 1 | baseline session: supine 2 | baseline session: straight leg raise test 2 | saline session: supine 1 | saline session: straight leg raise test 1 | saline session: supine 2 | saline session: straight leg raise 2 | naloxone session: supine 1 | naloxone session: straight leg raise 1 | naloxone session: supine 2 | naloxone session: straight leg raise 2 | |
| Mindfulness Meditation | 3.60 | 4.83 | 4.13 | 5.15 | 3.23 | 4.37 | 3.90 | 3.67 | 3.30 | 4.30 | 3.73 | 3.45 |
| Non Mindfulness Meditation | 4.69 | 5.41 | 4.76 | 5.78 | 4.62 | 5.75 | 4.37 | 5.32 | 4.82 | 6.10 | 5.18 | 5.52 |
This is a 12-item version of the SF-12 item Health Survey designed to assess general mental and physical functioning, and overall health-related quality of life. We used the physical functioning SF-12 scale and collected this information before and after each intervention and by group. The total range of scores is from 0 - 100. The minimum total score is 0 and the maximum score is 100. Higher scores indicate better functioning. (NCT04034004)
Timeframe: Up to 8 weeks. Administered at visit 1, 6 and 7. Outcome measurements will compare SF-12 health survey from baseline to session 7.
| Intervention | units on a scale (Mean) | |
|---|---|---|
| baseline SF physical functioning | session 7 SF physical functioning | |
| Mindfulness Meditation | 52.50 | 39.66 |
| Non-mindfulness Meditation | 49.17 | 44.83 |
The Roland-Morris Questionnaire (RMDQ) is a self-administered disability measure in which greater levels of disability are reflected by higher numbers on a 24-point scale. The RMDQ has been shown to yield reliable measurements, which are valid for inferring the level of disability, and to be sensitive to change over time for groups of patients with low back pain. Higher scores indicate greater disability. Total RMDQ scores are used before and after each intervention by group. The range of scores is from 0 - 24. (NCT04034004)
Timeframe: The Roland-Morris Disability Questionnaire was administered at the baseline, post-intervention session 6 and session 7. Outcome measurements will compare RMDQ from baseline to session 7.
| Intervention | units on a scale (Mean) | |
|---|---|---|
| baseline RMDQ | session 7 RMDQ | |
| Mindfulness Meditation | 12.86 | 12.03 |
| Non-mindfulness Meditation | 13.85 | 14.02 |
7 trials available for fentanyl and Back Pain
| Article | Year |
|---|---|
Dexamethasone added to local lidocaine for infiltration along the spinal-epidural needle pathway decreases incidence and severity of backache after gynecological surgery.
Topics: Adult; Anesthesia, Epidural; Anesthesia, Spinal; Anesthetics, Local; Back Pain; Dexamethasone; Femal | 2015 |
The Effect of Dexmedetomidine on Postoperative Opioid Consumption and Pain After Major Spine Surgery.
Topics: Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; Back Pain; Chi-Sq | 2016 |
Acute opioid administration improves work-related exercise performance in patients with chronic back pain.
Topics: Adult; Analgesics, Opioid; Back Pain; Chronic Disease; Cross-Over Studies; Double-Blind Method; Exer | 2008 |
Evaluation of therapeutic thoracic medial branch block effectiveness in chronic thoracic pain: a prospective outcome study with minimum 1-year follow up.
Topics: Adult; Back Pain; Chronic Disease; Disability Evaluation; Employment; Female; Fentanyl; Follow-Up St | 2006 |
Back pain after epidural anesthesia with chloroprocaine.
Topics: Adolescent; Adult; Aged; Analgesia, Epidural; Anesthesia, Epidural; Anesthetics, Local; Back Pain; D | 1993 |
Intrathecal fentanyl does not modify the duration of spinal procaine block.
Topics: Adolescent; Adult; Aged; Analgesics, Opioid; Anesthesia, Spinal; Anesthetics, Local; Back Pain; Bloo | 2001 |
Morbidity in gynaecological day-case surgery. A comparison of two anaesthetic techniques.
Topics: Abdomen; Ambulatory Surgical Procedures; Anesthesia, General; Back Pain; Dilatation and Curettage; F | 1979 |
24 other studies available for fentanyl and Back Pain
| Article | Year |
|---|---|
Effect of intradiscal local anesthetic injection on intraoperative pain during percutaneous transforaminal endoscopic discectomy: A retrospective study.
Topics: Anesthetics, Local; Back Pain; Diskectomy, Percutaneous; Fentanyl; Humans; Intervertebral Disc Displ | 2023 |
Comparative Effectiveness of Targeted Intrathecal Drug Delivery Using a Combination of Bupivacaine with Either Low-Dose Fentanyl or Hydromorphone in Chronic Back Pain Patients with Lumbar Postlaminectomy Syndrome.
Topics: Analgesics, Opioid; Anesthetics, Local; Back Pain; Bupivacaine; Fentanyl; Humans; Hydromorphone; Inj | 2020 |
Medical Use of Long-term Extended-release Opioid Analgesics in Commercially Insured Adults in the United States.
Topics: Adult; Aged; Analgesics, Opioid; Arthritis; Back Pain; Cancer Pain; Chronic Pain; Delayed-Action Pre | 2020 |
Alterations in endogenous opioid functional measures in chronic back pain.
Topics: Adult; Analgesics, Opioid; Analysis of Variance; Back Pain; Brain; Brain Mapping; Carbon Radioisotop | 2013 |
Alterations in endogenous opioid functional measures in chronic back pain.
Topics: Adult; Analgesics, Opioid; Analysis of Variance; Back Pain; Brain; Brain Mapping; Carbon Radioisotop | 2013 |
Alterations in endogenous opioid functional measures in chronic back pain.
Topics: Adult; Analgesics, Opioid; Analysis of Variance; Back Pain; Brain; Brain Mapping; Carbon Radioisotop | 2013 |
Alterations in endogenous opioid functional measures in chronic back pain.
Topics: Adult; Analgesics, Opioid; Analysis of Variance; Back Pain; Brain; Brain Mapping; Carbon Radioisotop | 2013 |
Serotonin syndrome: fentanyl and selective serotonin reuptake inhibitor interactions.
Topics: Adult; Anesthesia; Back Pain; Carpal Tunnel Syndrome; Depression; Drug Interactions; Female; Fentany | 2014 |
Chronic Back Pain Is Associated with Alterations in Dopamine Neurotransmission in the Ventral Striatum.
Topics: Adult; Analgesics, Opioid; Back Pain; Brain Mapping; Carbon Radioisotopes; Chronic Disease; Dopamine | 2015 |
Not so patchy story of attempted suicide…leading to 24 hours of deep sleep and survival!
Topics: Aged; Analgesics, Opioid; Back Pain; Chronic Pain; Drug Overdose; Female; Fentanyl; Humans; Suicide, | 2017 |
Case scenario: self-extraction of intrathecal pump medication with a concomitant intrathecal granulomatous mass.
Topics: Acetaminophen; Administration, Cutaneous; Adult; Analgesics; Analgesics, Non-Narcotic; Analgesics, O | 2011 |
Epidural lipomatosis causing new debilitating back pain in a patient with human immunodeficiency virus on highly active antiretroviral therapy.
Topics: Adult; Amines; Analgesics; Analgesics, Opioid; Anesthetics, Intravenous; Anti-Inflammatory Agents, N | 2012 |
I just started using a fentanyl patch for chronic back pain. What special precautions should I take?
Topics: Administration, Cutaneous; Analgesics, Opioid; Back Pain; Chronic Disease; Fentanyl; Humans; Patient | 2012 |
The role of fentanyl in refractory opioid-related acute colonic pseudo-obstruction.
Topics: Aged, 80 and over; Back Pain; Colonic Pseudo-Obstruction; Drug Substitution; Female; Fentanyl; Human | 2013 |
Transdermal fentanyl for the treatment of back pain caused by vertebral osteoporosis.
Topics: Administration, Cutaneous; Aged; Aged, 80 and over; Analgesics, Opioid; Back Pain; Female; Fentanyl; | 2002 |
Sedation with ketamine during intradiscal electrothermal therapy.
Topics: Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Back Pain; Conscious Sedation; Dose-Response Re | 2004 |
Oral transmucosal fentanyl citrate and xerostomia.
Topics: Administration, Buccal; Analgesics, Opioid; Back Pain; Bethanechol; Colonic Neoplasms; Drug Combinat | 2005 |
New pain management options: delivery systems and techniques.
Topics: Administration, Buccal; Administration, Cutaneous; Administration, Inhalation; Analgesia; Analgesia, | 2007 |
Spinal cord injury after accidental dural puncture for labour analgesia.
Topics: Adult; Analgesia, Epidural; Analgesia, Obstetrical; Anesthetics, Intravenous; Anesthetics, Local; Ba | 2007 |
When opioids cause pain.
Topics: Analgesics, Opioid; Back Pain; Carcinoma, Hepatocellular; Drug Therapy, Combination; Fentanyl; Human | 2007 |
Demand analgesia to assess pain relief from epidural opiates.
Topics: Anesthesia, Caudal; Anesthesia, Epidural; Back Pain; Computers; Fentanyl; Heroin; Humans; Injections | 1980 |
Back pain associated with the epidural injection of fentanyl.
Topics: Analgesia, Epidural; Back Pain; Fentanyl; Humans | 1995 |
Procaine spinal anesthesia: a pilot study of the incidence of transient neurologic symptoms.
Topics: Adult; Aged; Aged, 80 and over; Anesthesia Recovery Period; Anesthesia, Spinal; Anesthetics, Intrave | 1998 |
Inadvertent epidural gentamicin administration.
Topics: Adult; Analgesia, Epidural; Analgesics, Opioid; Back Pain; Female; Fentanyl; Gentamicins; Humans; Me | 1999 |
[Peridural analgesia in the combined treatment of neurologic syndromes in lumbar osteochondrosis].
Topics: Analgesia, Epidural; Analgesics, Opioid; Back Pain; Fentanyl; Humans; Injections, Spinal; Lumbar Ver | 1990 |
A simultaneous comparison of fentanyl's analgesic effects on experimental and clinical pain.
Topics: Affect; Back Pain; Fentanyl; Hot Temperature; Humans; Pain; Perception; Sensation | 1986 |
Diagnostic epidural opioid blockade and chronic pain: preliminary report.
Topics: Adult; Aged; Anesthesia, Epidural; Back Pain; Chronic Disease; Diagnosis, Differential; Female; Fent | 1985 |