Page last updated: 2024-10-27

fentanyl and Asthma

fentanyl has been researched along with Asthma in 14 studies

Fentanyl: A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078)
fentanyl : A monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of N-phenyl-1-(2-phenylethyl)piperidin-4-amine with propanoic acid.

Asthma: A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).

Research Excerpts

ExcerptRelevanceReference
"Sixty patients aged 18-75 yr taking bronchodilators chronically for asthma were anesthetized with midazolam, fentanyl, nitrous oxide, and isoflurane; the trachea was intubated without paralysis."9.08Atracurium versus vecuronium in asthmatic patients. A blinded, randomized comparison of adverse events. ( Caldwell, JE; Fisher, DM; Lau, M, 1995)
" The aim of the single-centre, evaluator-blinded, randomised clinical trial study was to evaluate whether continuous infusion of ketamine is associated with improvement in respiratory mechanics correlated with bronchospasm relief, as compared with continuous infusion of fentanyl."7.96Negative results for ketamine use in severe acute bronchospasm: a randomised controlled trial. ( Costa, R; Marin, L; Marques, L; Mendez, G; Nedel, W; Vargas, T, 2020)
"To determine how the probability of fentanyl-induced cough is affected by patient characteristics and/or anesthetic technique."7.73Identification of independent risk factors for fentanyl-induced cough. ( Dohi, S; Kasuya, Y; Murakami, T; Okumura, Y; Oshima, T, 2006)
"The use of etomidate and fentanyl infusions to sedate four asthmatics who required artificial ventilation and were receiving high dose steroids is described."7.67Sedating ventilated asthmatics: etomidate reconsidered. ( Eason, JR; Hanson, GC; Sebel, PS; Waldman, CS, 1988)
" We found a large heterogeneity regarding sample size, age and gender distribution, inclusion criteria (different severity scores, if any) and ketamine dosing (bolus and/or continuous infusion)."6.82Use of ketamine in patients with refractory severe asthma exacerbations: systematic review of prospective studies. ( Astuto, M; Brancati, S; Crimi, C; Cuttone, G; Dezio, V; Falcone, M; La Via, L; Sanfilippo, F, 2022)
"Sixty patients aged 18-75 yr taking bronchodilators chronically for asthma were anesthetized with midazolam, fentanyl, nitrous oxide, and isoflurane; the trachea was intubated without paralysis."5.08Atracurium versus vecuronium in asthmatic patients. A blinded, randomized comparison of adverse events. ( Caldwell, JE; Fisher, DM; Lau, M, 1995)
" The aim of the single-centre, evaluator-blinded, randomised clinical trial study was to evaluate whether continuous infusion of ketamine is associated with improvement in respiratory mechanics correlated with bronchospasm relief, as compared with continuous infusion of fentanyl."3.96Negative results for ketamine use in severe acute bronchospasm: a randomised controlled trial. ( Costa, R; Marin, L; Marques, L; Mendez, G; Nedel, W; Vargas, T, 2020)
"To determine how the probability of fentanyl-induced cough is affected by patient characteristics and/or anesthetic technique."3.73Identification of independent risk factors for fentanyl-induced cough. ( Dohi, S; Kasuya, Y; Murakami, T; Okumura, Y; Oshima, T, 2006)
"The use of etomidate and fentanyl infusions to sedate four asthmatics who required artificial ventilation and were receiving high dose steroids is described."3.67Sedating ventilated asthmatics: etomidate reconsidered. ( Eason, JR; Hanson, GC; Sebel, PS; Waldman, CS, 1988)
" We found a large heterogeneity regarding sample size, age and gender distribution, inclusion criteria (different severity scores, if any) and ketamine dosing (bolus and/or continuous infusion)."2.82Use of ketamine in patients with refractory severe asthma exacerbations: systematic review of prospective studies. ( Astuto, M; Brancati, S; Crimi, C; Cuttone, G; Dezio, V; Falcone, M; La Via, L; Sanfilippo, F, 2022)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19904 (28.57)18.7374
1990's2 (14.29)18.2507
2000's6 (42.86)29.6817
2010's0 (0.00)24.3611
2020's2 (14.29)2.80

Authors

AuthorsStudies
La Via, L1
Sanfilippo, F1
Cuttone, G1
Dezio, V1
Falcone, M1
Brancati, S1
Crimi, C1
Astuto, M1
Nedel, W1
Costa, R1
Mendez, G1
Marin, L1
Vargas, T1
Marques, L1
Awab, A1
Alilou, M1
El Moussaoui, R1
El Hijri, A1
Azzouzi, A1
Uvelin, A1
Rakic, G1
Hidano, G1
Nagata, O1
Narushima, M1
Ozaki, M1
Oshima, T1
Kasuya, Y1
Okumura, Y1
Murakami, T1
Dohi, S1
Gómez Ayechu, M1
Castañeda Pascual, M1
Zaballos Barcala, N1
Unzué Rico, P1
Caldwell, JE1
Lau, M1
Fisher, DM1
Kuwahara, B1
Goresky, GV1
Gerson, JI1
Eason, JR1
Waldman, CS1
Sebel, PS1
Hanson, GC1
Younker, D1
Clark, R1
Tessem, J1
Joyce, TH1
Kubicek, M1
Zeller, K1

Reviews

1 review available for fentanyl and Asthma

ArticleYear
Use of ketamine in patients with refractory severe asthma exacerbations: systematic review of prospective studies.
    European journal of clinical pharmacology, 2022, Volume: 78, Issue:10

    Topics: Adrenal Cortex Hormones; Adult; Aminophylline; Anti-Asthmatic Agents; Asthma; Child; Cholinergic Ant

2022

Trials

1 trial available for fentanyl and Asthma

ArticleYear
Atracurium versus vecuronium in asthmatic patients. A blinded, randomized comparison of adverse events.
    Anesthesiology, 1995, Volume: 83, Issue:5

    Topics: Adult; Aged; Anesthesia, General; Asthma; Atracurium; Female; Fentanyl; Hemodynamics; Humans; Male;

1995

Other Studies

12 other studies available for fentanyl and Asthma

ArticleYear
Negative results for ketamine use in severe acute bronchospasm: a randomised controlled trial.
    Anaesthesiology intensive therapy, 2020, Volume: 52, Issue:3

    Topics: Aged; Airway Resistance; Analgesics, Opioid; Anesthetics, Dissociative; Asthma; Bronchial Spasm; Bro

2020
[Rhabdomyolysis in severe acute asthma].
    Annales francaises d'anesthesie et de reanimation, 2009, Volume: 28, Issue:2

    Topics: Acidosis; Acute Disease; Adult; Albuterol; Anti-Asthmatic Agents; Asthma; Biomarkers; Combined Modal

2009
Guidelines for prevention of fentanyl-induced cough.
    Acta anaesthesiologica Scandinavica, 2009, Volume: 53, Issue:9

    Topics: Anesthesia, Intravenous; Anesthetics, Intravenous; Asthma; Cough; Fentanyl; Humans

2009
[Transient increase of bispectral index in a patient with bronchoconstriction after endotracheal intubation].
    Masui. The Japanese journal of anesthesiology, 2004, Volume: 53, Issue:1

    Topics: Anesthesia, General; Appendectomy; Asthma; Bronchial Diseases; Constriction, Pathologic; Female; Fen

2004
Identification of independent risk factors for fentanyl-induced cough.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2006, Volume: 53, Issue:8

    Topics: Adult; Age Factors; Anesthesia, Epidural; Anesthetics, Intravenous; Anesthetics, Local; Angiotensin-

2006
[Anesthetic implications of Swyer-James syndrome].
    Revista espanola de anestesiologia y reanimacion, 2006, Volume: 53, Issue:10

    Topics: Adolescent; Anesthesia, Intravenous; Asthma; Atracurium; Atropine; Bronchiectasis; Drainage; Fentany

2006
Anaesthetic management of an asthmatic child for appendicectomy.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1994, Volume: 41, Issue:6

    Topics: Adolescent; Albuterol; Anesthesia, Epidural; Appendectomy; Asthma; Beclomethasone; Bupivacaine; Fent

1994
Drugs for pain.
    The Medical letter on drugs and therapeutics, 2000, Aug-21, Volume: 42, Issue:1085

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal

2000
Intravenous fentanyl for the treatment of status asthmaticus.
    Critical care medicine, 1989, Volume: 17, Issue:4

    Topics: Asthma; Fentanyl; Humans; Injections, Intravenous; Status Asthmaticus

1989
Sedating ventilated asthmatics: etomidate reconsidered.
    Acta anaesthesiologica Belgica, 1988, Volume: 39, Issue:2

    Topics: Adolescent; Adult; Aged; Alfentanil; Asthma; Etomidate; Female; Fentanyl; Humans; Hydrocortisone; Hy

1988
Bupivacaine-fentanyl epidural analgesia for a parturient in status asthmaticus.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1987, Volume: 34, Issue:6

    Topics: Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Asthma; Bupivacaine; Female; Fentanyl; Humans;

1987
[Anesthesia in chronic patients].
    Bibliotheca tuberculosea, 1969, Volume: 25

    Topics: Adult; Aged; Anesthesia; Anesthetics; Anti-Bacterial Agents; Asthma; Benperidol; Chronic Disease; Fe

1969