Page last updated: 2024-10-27

fentanyl and Arthritis, Degenerative

fentanyl has been researched along with Arthritis, Degenerative in 7 studies

Fentanyl: A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078)
fentanyl : A monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of N-phenyl-1-(2-phenylethyl)piperidin-4-amine with propanoic acid.

Research Excerpts

ExcerptRelevanceReference
"Sixty nonsmoking female patients scheduled for elective knee osteoarthritis surgery were randomly allocated to receive oral aprepitant 80 mg (aprepitant+dexamethasone group, N."9.20Antiemetic efficacy of combined aprepitant and dexamethasone in patients at high-risk of postoperative nausea and vomiting from epidural fentanyl analgesia. ( Fujimoto, M; Hamaguchi, E; Kawano, H; Manabe, S; Matsumoto, T; Nakagawa, M; Tada, F; Yamada, A, 2015)
"This study was designed to evaluate the utility of transdermal fentanyl (transdermal fentanyl, TDF) for the treatment of pain due to osteoarthritis (osteoarthritis, OA) of the knee and hip, which was not adequately controlled by nonopioid analgesics or weak opioids."7.80Pain management in the elderly: transdermal fentanyl for the treatment of pain caused by osteoarthritis of the knee and hip. ( Mordarski, S, 2014)
"Although common treatments for osteoarthritis (OA) pain, such as nonsteroidal antiinflammatory drugs (NSAIDs), simple analgesics, and weak opioids, provide relief in some cases, they fail to control pain or are poorly tolerated in many cases."6.72Transdermal fentanyl for improvement of pain and functioning in osteoarthritis: a randomized, placebo-controlled trial. ( Langford, R; McKenna, F; Ratcliffe, S; Richarz, U; Vojtassák, J, 2006)
"Sixty nonsmoking female patients scheduled for elective knee osteoarthritis surgery were randomly allocated to receive oral aprepitant 80 mg (aprepitant+dexamethasone group, N."5.20Antiemetic efficacy of combined aprepitant and dexamethasone in patients at high-risk of postoperative nausea and vomiting from epidural fentanyl analgesia. ( Fujimoto, M; Hamaguchi, E; Kawano, H; Manabe, S; Matsumoto, T; Nakagawa, M; Tada, F; Yamada, A, 2015)
"This study was designed to evaluate the utility of transdermal fentanyl (transdermal fentanyl, TDF) for the treatment of pain due to osteoarthritis (osteoarthritis, OA) of the knee and hip, which was not adequately controlled by nonopioid analgesics or weak opioids."3.80Pain management in the elderly: transdermal fentanyl for the treatment of pain caused by osteoarthritis of the knee and hip. ( Mordarski, S, 2014)
"Although common treatments for osteoarthritis (OA) pain, such as nonsteroidal antiinflammatory drugs (NSAIDs), simple analgesics, and weak opioids, provide relief in some cases, they fail to control pain or are poorly tolerated in many cases."2.72Transdermal fentanyl for improvement of pain and functioning in osteoarthritis: a randomized, placebo-controlled trial. ( Langford, R; McKenna, F; Ratcliffe, S; Richarz, U; Vojtassák, J, 2006)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19901 (14.29)18.7374
1990's0 (0.00)18.2507
2000's2 (28.57)29.6817
2010's4 (57.14)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mordarski, S1
Kawano, H1
Matsumoto, T1
Hamaguchi, E1
Manabe, S1
Nakagawa, M1
Yamada, A1
Fujimoto, M1
Tada, F1
Khanna, A1
Saxena, R1
Dutta, A1
Ganguly, N1
Sood, J1
Brune, K1
Stammschulte, T1
Langford, R1
McKenna, F1
Ratcliffe, S1
Vojtassák, J1
Richarz, U1
Bannwarth, B1
Stanton-Hicks, MD1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effectiveness of Spa Treatment in Patients With Spine Osteoarthritis in Comparison With Outpatient Physiotherapy and no Physiotherapy[NCT03974308]300 participants (Actual)Interventional2019-04-20Completed
Effect of the Association of Neurokinin-1 Receptor Antagonist Aprepitant to Dexamethasone/Ondansetron in the Incidence of Postoperative Nausea and Vomiting in High Risk Apfel Score Patients[NCT02357693]Phase 490 participants (Actual)Interventional2015-02-28Completed
Comparison of the Effect of Intra-articular Administration of 2% Ropivacaine vs. 7.5% Ropivacaine as an Analgesic in the Immediate Postoperative Period of Knee Arthroscopy in Acute Injuries at the ABC Medical Center[NCT05807945]Phase 468 participants (Actual)Interventional2020-04-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

3 trials available for fentanyl and Arthritis, Degenerative

ArticleYear
Antiemetic efficacy of combined aprepitant and dexamethasone in patients at high-risk of postoperative nausea and vomiting from epidural fentanyl analgesia.
    Minerva anestesiologica, 2015, Volume: 81, Issue:4

    Topics: Aged; Analgesia, Epidural; Analgesics, Opioid; Antiemetics; Aprepitant; Dexamethasone; Female; Fenta

2015
Comparison of ropivacaine with and without fentanyl vs bupivacaine with fentanyl for postoperative epidural analgesia in bilateral total knee replacement surgery.
    Journal of clinical anesthesia, 2017, Volume: 37

    Topics: Aged; Amides; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthetics, L

2017
Transdermal fentanyl for improvement of pain and functioning in osteoarthritis: a randomized, placebo-controlled trial.
    Arthritis and rheumatism, 2006, Volume: 54, Issue:6

    Topics: Administration, Cutaneous; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Female; Fentanyl; Hum

2006

Other Studies

4 other studies available for fentanyl and Arthritis, Degenerative

ArticleYear
Pain management in the elderly: transdermal fentanyl for the treatment of pain caused by osteoarthritis of the knee and hip.
    BioMed research international, 2014, Volume: 2014

    Topics: Administration, Cutaneous; Aged; Aged, 80 and over; Female; Fentanyl; Hip; Humans; Knee; Male; Middl

2014
[Transdermal fentanyl: what if doctor and pharmacist fail?].
    MMW Fortschritte der Medizin, 2010, Apr-15, Volume: 152, Issue:15

    Topics: Administration, Cutaneous; Analgesics, Opioid; Dose-Response Relationship, Drug; Female; Fentanyl; G

2010
Transdermal fentanyl in patients with osteoarthritis: comment on the article by Langford et al.
    Arthritis and rheumatism, 2007, Volume: 56, Issue:2

    Topics: Administration, Cutaneous; Analgesics, Opioid; Arthralgia; Dose-Response Relationship, Drug; Fentany

2007
A study using bupivacaine for continuous peridural analgesia in patients undergoing surgery of the hip.
    Acta anaesthesiologica Scandinavica, 1971, Volume: 15, Issue:2

    Topics: Adult; Age Factors; Aged; Anesthesia, Conduction; Anesthesia, Epidural; Anesthesia, Spinal; Anesthet

1971