Page last updated: 2024-10-27

fentanyl and Arm Injuries

fentanyl has been researched along with Arm Injuries in 9 studies

Fentanyl: A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078)
fentanyl : A monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of N-phenyl-1-(2-phenylethyl)piperidin-4-amine with propanoic acid.

Arm Injuries: General or unspecified injuries involving the UPPER ARM and the FOREARM.

Research Excerpts

ExcerptRelevanceReference
"The use of OTFC can provide improved pain control when compared with IV morphine."9.12A randomized clinical trial of oral transmucosal fentanyl citrate versus intravenous morphine sulfate for initial control of pain in children with extremity injuries. ( Christopher, NC; Kennedy, CS; Mahar, PJ; Rana, JA, 2007)
"5 μg/kg intranasal fentanyl in children 4 to 17 years old with acute pain from suspected isolated extremity fractures presenting to an urban Level II pediatric trauma center from December 2015 to November 2016."5.24Randomized Controlled Feasibility Trial of Intranasal Ketamine Compared to Intranasal Fentanyl for Analgesia in Children with Suspected Extremity Fractures. ( Bryant, KK; Dunn, C; Hogg, M; Moore, CG; Reynolds, SL; Runyon, MS; Studnek, JR; Templin, MA; Walker, KR; Young, JR, 2017)
"The use of OTFC can provide improved pain control when compared with IV morphine."5.12A randomized clinical trial of oral transmucosal fentanyl citrate versus intravenous morphine sulfate for initial control of pain in children with extremity injuries. ( Christopher, NC; Kennedy, CS; Mahar, PJ; Rana, JA, 2007)
"A 26-year-old man presented with severe complex regional pain syndrome type I of the affected limb after a work-related electrical injury."1.31Complex regional pain syndrome (type I) after electrical injury: a case report of treatment with continuous epidural block. ( Bryant, P; Kim, CT, 2001)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19901 (11.11)18.7374
1990's0 (0.00)18.2507
2000's3 (33.33)29.6817
2010's5 (55.56)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Reynolds, SL1
Bryant, KK1
Studnek, JR1
Hogg, M1
Dunn, C1
Templin, MA1
Moore, CG1
Young, JR1
Walker, KR1
Runyon, MS1
Graudins, A1
Meek, R1
Egerton-Warburton, D1
Seith, R1
Furness, T1
Chapman, R1
Alimohammadi, H1
Azizi, MR1
Safari, S1
Amini, A1
Kariman, H1
Hatamabadi, HR1
Farahmand, S1
Shiralizadeh, S1
Talebian, MT1
Bagheri-Hariri, S1
Arbab, M1
Basirghafouri, H1
Saeedi, M1
Sedaghat, M1
Mirzababai, H1
Borland, ML1
Clark, LJ1
Esson, A1
Crellin, D1
Ling, RX1
Babl, FE1
Mahar, PJ1
Rana, JA1
Kennedy, CS1
Christopher, NC1
Kim, CT1
Bryant, P1
Oseev, VV1
Timofeev, VV1
Tsybuliak, GN1
Meshcheriakov, AV1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Comparison of Sub-dissociative Dose Intranasal Ketamine to Intranasal Fentanyl for Treatment of Moderate to Severe Pain in Pediatric Patients Presenting to the Emergency Department: a Prospective, Randomized, Double-blind Study[NCT02388321]Phase 422 participants (Actual)Interventional2015-05-01Terminated (stopped due to Patients meeting inclusion criteria was low, and PI went to another institution.)
Prehospital Analgesia With Intra-Nasal Ketamine[NCT02753114]Phase 4120 participants (Actual)Interventional2017-11-06Completed
Intranasal Sufentanil for Analgesia of Severe Sickle Cell Vaso-occlusive Pain Crisis in the Pediatric Emergency Department: a Double Blind Randomized Versus Placebo Controlled Trial[NCT06181695]Phase 3182 participants (Anticipated)Interventional2024-05-02Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Adverse Events at 30 Minutes

The patient were asked at 30 minutes post administration of analgesia if they experienced any side effects like nausea, vomiting, headache etc. (NCT02388321)
Timeframe: 30 minutes

InterventionParticipants (Count of Participants)
Ketamine0
Fentanyl0

Pain Score at 30 Minutes

An 11 point Likert Visual Analog Scale with 0 being no pain, 5 being moderate pain and 10 being very severe pain was verbally administered to the patient at 30 minutes post administration of analgesia. (NCT02388321)
Timeframe: 30 minutes

Interventionunits on a scale (Mean)
Ketamine3.36
Fentanyl2.09

Trials

5 trials available for fentanyl and Arm Injuries

ArticleYear
Randomized Controlled Feasibility Trial of Intranasal Ketamine Compared to Intranasal Fentanyl for Analgesia in Children with Suspected Extremity Fractures.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2017, Volume: 24, Issue:12

    Topics: Acute Pain; Administration, Intranasal; Adolescent; Analgesics; Arm Injuries; Child; Child, Preschoo

2017
The PICHFORK (Pain InCHildren Fentanyl OR Ketamine) trial comparing the efficacy of intranasal ketamine and fentanyl in the relief of moderate to severe pain in children with limb injuries: study protocol for a randomized controlled trial.
    Trials, 2013, Jul-10, Volume: 14

    Topics: Administration, Intranasal; Adolescent; Age Factors; Analgesics; Analgesics, Opioid; Arm Injuries; C

2013
Axillary nerve block in comparison with intravenous midazolam/fentanyl for painless reduction of upper extremity fractures.
    Acta medica Iranica, 2014, Volume: 52, Issue:2

    Topics: Analgesics, Opioid; Arm Injuries; Axilla; Drug Therapy, Combination; Fentanyl; Fractures, Bone; Huma

2014
Nebulized fentanyl vs intravenous morphine for ED patients with acute limb pain: a randomized clinical trial.
    The American journal of emergency medicine, 2014, Volume: 32, Issue:9

    Topics: Acute Pain; Administration, Inhalation; Adult; Analgesics, Opioid; Arm Injuries; Double-Blind Method

2014
A randomized clinical trial of oral transmucosal fentanyl citrate versus intravenous morphine sulfate for initial control of pain in children with extremity injuries.
    Pediatric emergency care, 2007, Volume: 23, Issue:8

    Topics: Administration, Oral; Adolescent; Analgesics, Opioid; Arm Injuries; Child; Female; Fentanyl; Humans;

2007

Other Studies

4 other studies available for fentanyl and Arm Injuries

ArticleYear
Comparative review of the clinical use of intranasal fentanyl versus morphine in a paediatric emergency department.
    Emergency medicine Australasia : EMA, 2008, Volume: 20, Issue:6

    Topics: Abdominal Pain; Administration, Intranasal; Analgesics, Opioid; Arm Injuries; Child; Child, Preschoo

2008
Comparative review of the clinical use of intranasal fentanyl versus morphine in a paediatric emergency department.
    Emergency medicine Australasia : EMA, 2008, Volume: 20, Issue:6

    Topics: Abdominal Pain; Administration, Intranasal; Analgesics, Opioid; Arm Injuries; Child; Child, Preschoo

2008
Comparative review of the clinical use of intranasal fentanyl versus morphine in a paediatric emergency department.
    Emergency medicine Australasia : EMA, 2008, Volume: 20, Issue:6

    Topics: Abdominal Pain; Administration, Intranasal; Analgesics, Opioid; Arm Injuries; Child; Child, Preschoo

2008
Comparative review of the clinical use of intranasal fentanyl versus morphine in a paediatric emergency department.
    Emergency medicine Australasia : EMA, 2008, Volume: 20, Issue:6

    Topics: Abdominal Pain; Administration, Intranasal; Analgesics, Opioid; Arm Injuries; Child; Child, Preschoo

2008
Does the standard intravenous solution of fentanyl (50 microg/mL) administered intranasally have analgesic efficacy?
    Emergency medicine Australasia : EMA, 2010, Volume: 22, Issue:1

    Topics: Administration, Intranasal; Adolescent; Analgesics, Opioid; Arm Injuries; Child; Child, Preschool; E

2010
Complex regional pain syndrome (type I) after electrical injury: a case report of treatment with continuous epidural block.
    Archives of physical medicine and rehabilitation, 2001, Volume: 82, Issue:7

    Topics: Adult; Analgesics, Opioid; Anesthetics, Local; Arm Injuries; Burns, Electric; Complex Regional Pain

2001
[Initial experience in neuroleptoanalgesia in the surgery of injuries].
    Vestnik khirurgii imeni I. I. Grekova, 1968, Volume: 100, Issue:6

    Topics: Adolescent; Adult; Amputation, Surgical; Arm Injuries; Benperidol; Female; Fentanyl; Fractures, Bone

1968