Page last updated: 2024-10-27

fentanyl and Anoxia, Brain

fentanyl has been researched along with Anoxia, Brain in 7 studies

Fentanyl: A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078)
fentanyl : A monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of N-phenyl-1-(2-phenylethyl)piperidin-4-amine with propanoic acid.

Research Excerpts

ExcerptRelevanceReference
"These findings suggest that xylazine exacerbates the life-threatening effects of opioids, proposing worsened brain hypoxia as the mechanism contributing to xylazine-positive opioid-overdose deaths."8.31Xylazine effects on opioid-induced brain hypoxia. ( Choi, S; Irwin, MR; Kiyatkin, EA, 2023)
"Fentanyl is a potent synthetic opioid used extensively in humans for general anesthesia and analgesia."5.48Fentanyl-Induced Brain Hypoxia Triggers Brain Hyperglycemia and Biphasic Changes in Brain Temperature. ( Cameron-Burr, KT; Kiyatkin, EA; Shaham, Y; Solis, E, 2018)
" Here, we focused on the basic physiological effects of ketamine as a recreational drug and its possible interactions with fentanyl-a highly potent opioid that induces strong respiratory depression and robust brain hypoxia."4.31Basic metabolic and vascular effects of ketamine and its interaction with fentanyl. ( Choi, S; Curay, CM; Irwin, MR; Kiyatkin, EA, 2023)
"These findings suggest that xylazine exacerbates the life-threatening effects of opioids, proposing worsened brain hypoxia as the mechanism contributing to xylazine-positive opioid-overdose deaths."4.31Xylazine effects on opioid-induced brain hypoxia. ( Choi, S; Irwin, MR; Kiyatkin, EA, 2023)
"Respiratory depression that leads to brain hypoxia is perhaps the most dangerous symptom of acute intoxication with opioids, and it could result in lethality."2.61Respiratory depression and brain hypoxia induced by opioid drugs: Morphine, oxycodone, heroin, and fentanyl. ( Kiyatkin, EA, 2019)
" While low dosing is thought to be a factor limiting naloxone's efficacy, the timing between fentanyl exposure and initiation of naloxone treatment may be another important factor."1.91The pattern of brain oxygen response induced by intravenous fentanyl limits the time window of therapeutic efficacy of naloxone. ( Curay, CM; Irwin, MR; Kiyatkin, EA, 2023)
"Fentanyl is a potent synthetic opioid used extensively in humans for general anesthesia and analgesia."1.48Fentanyl-Induced Brain Hypoxia Triggers Brain Hyperglycemia and Biphasic Changes in Brain Temperature. ( Cameron-Burr, KT; Kiyatkin, EA; Shaham, Y; Solis, E, 2018)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (28.57)29.6817
2010's2 (28.57)24.3611
2020's3 (42.86)2.80

Authors

AuthorsStudies
Irwin, MR3
Curay, CM2
Choi, S2
Kiyatkin, EA5
Solis, E1
Cameron-Burr, KT1
Shaham, Y1
Shprecher, DR1
Flanigan, KM1
Smith, AG1
Smith, SM1
Schenkenberg, T1
Steffens, J1
Ammon-Treiber, S1
Stolze, D1
Höllt, V1

Reviews

1 review available for fentanyl and Anoxia, Brain

ArticleYear
Respiratory depression and brain hypoxia induced by opioid drugs: Morphine, oxycodone, heroin, and fentanyl.
    Neuropharmacology, 2019, Volume: 151

    Topics: Analgesics, Opioid; Animals; Brain; Fentanyl; Heroin; Humans; Hypoxia, Brain; Morphine; Oxycodone; R

2019

Other Studies

6 other studies available for fentanyl and Anoxia, Brain

ArticleYear
Basic metabolic and vascular effects of ketamine and its interaction with fentanyl.
    Neuropharmacology, 2023, 05-01, Volume: 228

    Topics: Analgesics, Opioid; Animals; Fentanyl; Humans; Hypoxia; Hypoxia, Brain; Ketamine; Oxygen; Rats

2023
The pattern of brain oxygen response induced by intravenous fentanyl limits the time window of therapeutic efficacy of naloxone.
    Neuropharmacology, 2023, 06-15, Volume: 231

    Topics: Analgesics, Opioid; Animals; Brain; Fentanyl; Hypoxia; Hypoxia, Brain; Naloxone; Narcotic Antagonist

2023
Xylazine effects on opioid-induced brain hypoxia.
    Psychopharmacology, 2023, Volume: 240, Issue:7

    Topics: Analgesics, Opioid; Animals; Drug Overdose; Fentanyl; Heroin; Humans; Hypothermia; Hypoxia; Hypoxia,

2023
Fentanyl-Induced Brain Hypoxia Triggers Brain Hyperglycemia and Biphasic Changes in Brain Temperature.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2018, Volume: 43, Issue:4

    Topics: Analgesics, Opioid; Animals; Body Temperature; Brain; Fentanyl; Glucose; Hyperglycemia; Hypoxia, Bra

2018
Clinical and diagnostic features of delayed hypoxic leukoencephalopathy.
    The Journal of neuropsychiatry and clinical neurosciences, 2008,Fall, Volume: 20, Issue:4

    Topics: Adult; Analgesics, Opioid; Benzodiazepines; Brain; Cocaine; Cognition Disorders; Depressive Disorder

2008
Differential effects of mu-opioid receptor agonists in a hippocampal hypoxia/hypoglycemia model.
    Brain research, 2007, Dec-05, Volume: 1183

    Topics: Analgesics, Opioid; Animals; Data Interpretation, Statistical; Electrophysiology; Enkephalin, Ala(2)

2007