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fentanyl and Airflow Obstruction, Chronic

fentanyl has been researched along with Airflow Obstruction, Chronic in 13 studies

Fentanyl: A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078)
fentanyl : A monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of N-phenyl-1-(2-phenylethyl)piperidin-4-amine with propanoic acid.

Research Excerpts

ExcerptRelevanceReference
" The aim of the single-centre, evaluator-blinded, randomised clinical trial study was to evaluate whether continuous infusion of ketamine is associated with improvement in respiratory mechanics correlated with bronchospasm relief, as compared with continuous infusion of fentanyl."7.96Negative results for ketamine use in severe acute bronchospasm: a randomised controlled trial. ( Costa, R; Marin, L; Marques, L; Mendez, G; Nedel, W; Vargas, T, 2020)
"To evaluate the efficacy and safety of oral transmucosal fentanyl citrate (OTFC) in terminally ill patients experiencing dyspnea."7.74Oral transmucosal fentanyl citrate for dyspnea in terminally ill patients: an observational case series. ( Gauna, AA; Kang, SK; Swatko, ER; Triano, ML; Vanston, VJ, 2008)
"To determine how the probability of fentanyl-induced cough is affected by patient characteristics and/or anesthetic technique."7.73Identification of independent risk factors for fentanyl-induced cough. ( Dohi, S; Kasuya, Y; Murakami, T; Okumura, Y; Oshima, T, 2006)
" Low dosed opioids have been investigated for refractory dyspnea in COPD and other life-limiting conditions, and some positive effects were demonstrated."6.72Opioids in patients with COPD and refractory dyspnea: literature review and design of a multicenter double blind study of low dosed morphine and fentanyl (MoreFoRCOPD). ( de Hosson, SM; Heller-Baan, R; Kerstjens, HAM; Lam-Wong, WY; Mooren, KJM; Peters, L; Pool, K; van Beurden-Moeskops, WJC; van den Berg, JK; van Dijk, M, 2021)
"Fentanyl is an appropriate drug because of its fast onset and short duration of action."6.45[Nasal application of fentanyl citrate as symptom control against breathlessness in palliative care--overview and case report]. ( Sitte, T, 2009)
" The aim of the single-centre, evaluator-blinded, randomised clinical trial study was to evaluate whether continuous infusion of ketamine is associated with improvement in respiratory mechanics correlated with bronchospasm relief, as compared with continuous infusion of fentanyl."3.96Negative results for ketamine use in severe acute bronchospasm: a randomised controlled trial. ( Costa, R; Marin, L; Marques, L; Mendez, G; Nedel, W; Vargas, T, 2020)
"We aim to describe management of a patient receiving renal transplantation for chronic renal failure due to Alport syndrome with low dose of intrathecal bupivacaine and continuous epidural infusion of local anesthetic."3.83Low-dose Spinal Block With Continuous Epidural Infusion for Renal Transplantation in a Patient With Alport Syndrome: A Case Report. ( Brazzi, L; Bretto, P; Donadio, PP; Gobbi, F; Sales, G, 2016)
"To evaluate the efficacy and safety of oral transmucosal fentanyl citrate (OTFC) in terminally ill patients experiencing dyspnea."3.74Oral transmucosal fentanyl citrate for dyspnea in terminally ill patients: an observational case series. ( Gauna, AA; Kang, SK; Swatko, ER; Triano, ML; Vanston, VJ, 2008)
"To determine how the probability of fentanyl-induced cough is affected by patient characteristics and/or anesthetic technique."3.73Identification of independent risk factors for fentanyl-induced cough. ( Dohi, S; Kasuya, Y; Murakami, T; Okumura, Y; Oshima, T, 2006)
"Nevertheless, many patients with COPD remain incapacitated by dyspnea and exercise intolerance despite optimal therapy."2.77Inhaled fentanyl citrate improves exercise endurance during high-intensity constant work rate cycle exercise in chronic obstructive pulmonary disease. ( Alsuhail, A; Dudgeon, DJ; Jensen, D; O'Donnell, DE; Viola, R; Webb, KA, 2012)
" Low dosed opioids have been investigated for refractory dyspnea in COPD and other life-limiting conditions, and some positive effects were demonstrated."2.72Opioids in patients with COPD and refractory dyspnea: literature review and design of a multicenter double blind study of low dosed morphine and fentanyl (MoreFoRCOPD). ( de Hosson, SM; Heller-Baan, R; Kerstjens, HAM; Lam-Wong, WY; Mooren, KJM; Peters, L; Pool, K; van Beurden-Moeskops, WJC; van den Berg, JK; van Dijk, M, 2021)
"Fentanyl is an appropriate drug because of its fast onset and short duration of action."2.45[Nasal application of fentanyl citrate as symptom control against breathlessness in palliative care--overview and case report]. ( Sitte, T, 2009)
"In patients with chronic obstructive pulmonary disease (COPD), IF also elicits sustained decreases in the exercise ventilatory response but with little or no resultant CO2 retention due to concomitant decreases in physiological VD/VT (dead space-to-ventilation ratio)."1.42Type III-IV muscle afferents are not required for steady-state exercise hyperpnea in healthy subjects and patients with COPD or heart failure. ( Poon, CS; Song, G, 2015)
"In high-risk patients (severe COPD), open surgical repair of infrarenal AAA may be done with CSEA alone without intubation when, because of the patient's health, general anesthesia would pose too high a risk or when EVAR is unfeasible."1.36Combined spinal and epidural anesthesia for open abdominal aortic aneurysm surgery in vigil patients with severe chronic obstructive pulmonary disease ineligible for endovascular aneurysm repair. Analysis of results and description of the technique. ( Berardi, G; Bianchi, A; Cumbo, P; Fadde, M; Ferrero, E; Ferri, M; Gaggiano, A; Ganzaroli, M; Lamorgese, V; Lojacono, N; Maggio, D; Nessi, F; Piazza, S; Verdecchia, C; Viazzo, A, 2010)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (38.46)29.6817
2010's6 (46.15)24.3611
2020's2 (15.38)2.80

Authors

AuthorsStudies
van Dijk, M1
Mooren, KJM1
van den Berg, JK1
van Beurden-Moeskops, WJC1
Heller-Baan, R1
de Hosson, SM1
Lam-Wong, WY1
Peters, L1
Pool, K1
Kerstjens, HAM1
Nedel, W1
Costa, R1
Mendez, G1
Marin, L1
Vargas, T1
Marques, L1
Poon, CS1
Song, G1
Gobbi, F1
Sales, G1
Bretto, P1
Donadio, PP1
Brazzi, L1
Parras Maldonado, MT1
Ramos Lozano, R1
García Saura, PL1
Lorite Rascón, A1
Martínez Gámez, J1
Horton, R1
Barber, C1
Sitte, T1
Berardi, G1
Ferrero, E1
Fadde, M1
Lojacono, N1
Ferri, M1
Viazzo, A1
Gaggiano, A1
Bianchi, A1
Maggio, D1
Ganzaroli, M1
Piazza, S1
Cumbo, P1
Lamorgese, V1
Verdecchia, C1
Nessi, F1
Jensen, D1
Alsuhail, A1
Viola, R1
Dudgeon, DJ1
Webb, KA1
O'Donnell, DE1
Gagnon, P1
Bussières, JS1
Ribeiro, F1
Gagnon, SL1
Saey, D1
Gagné, N1
Provencher, S1
Maltais, F1
Kapoor, S1
Oshima, T1
Kasuya, Y1
Okumura, Y1
Murakami, T1
Dohi, S1
Gauna, AA1
Kang, SK1
Triano, ML1
Swatko, ER1
Vanston, VJ1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Morphine or Fentanyl for Refractory Dyspnea in COPD[NCT03834363]Phase 460 participants (Anticipated)Interventional2019-11-15Recruiting
Impact of Somatosensory Feedback on Peripheral Muscle Fatigue and Exercise Tolerance in Patients With COPD[NCT01522729]8 participants (Actual)Interventional2010-10-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for fentanyl and Airflow Obstruction, Chronic

ArticleYear
Opioids in patients with COPD and refractory dyspnea: literature review and design of a multicenter double blind study of low dosed morphine and fentanyl (MoreFoRCOPD).
    BMC pulmonary medicine, 2021, Sep-10, Volume: 21, Issue:1

    Topics: Analgesics, Opioid; Dose-Response Relationship, Drug; Double-Blind Method; Dyspnea; Fentanyl; Health

2021
[Nasal application of fentanyl citrate as symptom control against breathlessness in palliative care--overview and case report].
    Wiener medizinische Wochenschrift (1946), 2009, Volume: 159, Issue:23-24

    Topics: Acute Disease; Administration, Cutaneous; Administration, Intranasal; Aged, 80 and over; Ambulatory

2009

Trials

2 trials available for fentanyl and Airflow Obstruction, Chronic

ArticleYear
Inhaled fentanyl citrate improves exercise endurance during high-intensity constant work rate cycle exercise in chronic obstructive pulmonary disease.
    Journal of pain and symptom management, 2012, Volume: 43, Issue:4

    Topics: Administration, Inhalation; Aged; Analgesics, Opioid; Cross-Over Studies; Double-Blind Method; Exerc

2012
Influences of spinal anesthesia on exercise tolerance in patients with chronic obstructive pulmonary disease.
    American journal of respiratory and critical care medicine, 2012, Oct-01, Volume: 186, Issue:7

    Topics: Afferent Pathways; Aged; Analgesics, Opioid; Anesthesia, Spinal; Cross-Over Studies; Double-Blind Me

2012

Other Studies

9 other studies available for fentanyl and Airflow Obstruction, Chronic

ArticleYear
Negative results for ketamine use in severe acute bronchospasm: a randomised controlled trial.
    Anaesthesiology intensive therapy, 2020, Volume: 52, Issue:3

    Topics: Aged; Airway Resistance; Analgesics, Opioid; Anesthetics, Dissociative; Asthma; Bronchial Spasm; Bro

2020
Type III-IV muscle afferents are not required for steady-state exercise hyperpnea in healthy subjects and patients with COPD or heart failure.
    Respiratory physiology & neurobiology, 2015, Sep-15, Volume: 216

    Topics: Analgesics, Opioid; Electromyography; Exercise; Female; Fentanyl; Heart Failure; Heart Rate; Humans;

2015
Low-dose Spinal Block With Continuous Epidural Infusion for Renal Transplantation in a Patient With Alport Syndrome: A Case Report.
    Transplantation proceedings, 2016, Volume: 48, Issue:9

    Topics: Adult; Analgesia, Epidural; Anesthesia, Epidural; Anesthesia, General; Anesthesia, Spinal; Anestheti

2016
[Endovascular treatment of a ruptured abdominal aorta aneurysm with local anesthesia, sedation and analgesia].
    Revista espanola de anestesiologia y reanimacion, 2009, Volume: 56, Issue:3

    Topics: Acetaminophen; Analgesics; Anesthesia, General; Anesthesia, Local; Aortic Aneurysm, Abdominal; Aorti

2009
Opioid-induced respiratory depression resulting from transdermal fentanyl-clarithromycin drug interaction in a patient with advanced COPD.
    Journal of pain and symptom management, 2009, Volume: 37, Issue:6

    Topics: Administration, Cutaneous; Aged, 80 and over; Analgesics, Opioid; Anti-Bacterial Agents; Clarithromy

2009
Combined spinal and epidural anesthesia for open abdominal aortic aneurysm surgery in vigil patients with severe chronic obstructive pulmonary disease ineligible for endovascular aneurysm repair. Analysis of results and description of the technique.
    International angiology : a journal of the International Union of Angiology, 2010, Volume: 29, Issue:3

    Topics: Adjuvants, Anesthesia; Aged; Aged, 80 and over; Anesthesia, Epidural; Anesthesia, Spinal; Anesthetic

2010
Emerging opioid alternatives to nebulized fentanyl for improving exercise capacity in patients with COPD.
    Journal of pain and symptom management, 2012, Volume: 44, Issue:4

    Topics: Exercise Tolerance; Female; Fentanyl; Humans; Male; Physical Exertion; Pulmonary Disease, Chronic Ob

2012
Identification of independent risk factors for fentanyl-induced cough.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2006, Volume: 53, Issue:8

    Topics: Adult; Age Factors; Anesthesia, Epidural; Anesthetics, Intravenous; Anesthetics, Local; Angiotensin-

2006
Oral transmucosal fentanyl citrate for dyspnea in terminally ill patients: an observational case series.
    Journal of palliative medicine, 2008, Volume: 11, Issue:4

    Topics: Aged; Aged, 80 and over; Analgesics, Opioid; Dyspnea; Female; Fentanyl; Heart Failure; Humans; Lung

2008