fentanyl has been researched along with Agitated Emergence in 12 studies
Fentanyl: A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078)
fentanyl : A monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of N-phenyl-1-(2-phenylethyl)piperidin-4-amine with propanoic acid.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Lidocaine-based regimen for induction of anesthesia reduced the risk of postinduction hypotension in older patients compared to the fentanyl-based regimen." | 5.69 | Comparison of the hemodynamic effects of opioid-based versus lidocaine-based induction of anesthesia with propofol in older adults: a randomized controlled trial. ( Amin, SM; Arafa, AS; ElSayed, OS; Hasanin, A; Hassan, A; Khaled, D; Mostafa, M, 2023) |
| "Sevoflurane or fentanyl was titrated immediately according to monitor thresholds." | 3.11 | Emergence agitation in paediatric day case surgery: A randomised, single-blinded study comparing narcotrend and heart rate variability with standard monitoring. ( Erngaard, L; Hansen, TG; Larsen, LG; Lé Greves, S; Wegger, M, 2022) |
| "The incidence of emergence delirium was lower in the dexmedetomidine group than in the melatonin group (17 versus 37%, relative risk 0." | 3.11 | Atomised intranasal dexmedetomidine versus oral melatonin in prevention of emergence delirium in children undergoing ophthalmic surgery with sevoflurane: A randomised double-blind study. ( Ashok, V; Jangra, S; Ram, J; Sethi, S, 2022) |
| "Remifentanil has a significant effect on reducing the occurrence of delirium (P = 0." | 2.84 | The influence of analgesic-based sedation protocols on delirium and outcomes in critically ill patients: A randomized controlled trial. ( An, Y; Liu, D; Lyu, J; Zhao, H, 2017) |
| "Incidence of EA and postoperative pain scores were recorded at 10-min intervals in the postanaesthetic care unit (PACU)." | 2.82 | Comparison of effects of intravenous midazolam and ketamine on emergence agitation in children: Randomized controlled trial. ( Jung, JW; Kang, E; Kim, KM; Kim, YH; Ko, MJ; Lee, KH, 2016) |
| "Fentanyl dose response was evidenced by oxycodone administration differences ( P ≤ 0." | 1.91 | Middle Ear Condition at the Time of Pediatric Myringotomy Tube Placement: Pain Associations Following Intraoperative Fentanyl/Ketorolac and Seasonal Variation. ( Ampah, SB; Cohen, WG; Cook-Sather, SD; Lee, DR; Sobol, SE; Zhang, B, 2023) |
| "Postoperative pain was evaluated using the Children's Hospital of Eastern Ontario Pain Scale (CHEOPS) and the rescue fentanyl requirement in post anesthesia care unit (PACU) was analyzed." | 1.72 | Association between ABO blood groups and postoperative pain in children after adenotonsillectomy: a prospective cohort study. ( Guo, G; Hong, M; Lian, J; Lin, X; Luo, Q; Shen, L; Wang, J; Wang, S; Wu, J; Xiao, Q; Xu, Y, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 6 (50.00) | 24.3611 |
| 2020's | 6 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sun, M | 1 |
| Peng, T | 1 |
| Sun, Y | 2 |
| Huang, Z | 1 |
| Jiang, J | 1 |
| Wang, C | 1 |
| Li, Y | 2 |
| Zhang, Y | 1 |
| Kong, W | 1 |
| Fan, L | 1 |
| Sun, X | 1 |
| Zhao, X | 1 |
| Larsen, LG | 1 |
| Wegger, M | 1 |
| Lé Greves, S | 1 |
| Erngaard, L | 1 |
| Hansen, TG | 1 |
| Jangra, S | 1 |
| Ashok, V | 1 |
| Sethi, S | 1 |
| Ram, J | 1 |
| Cohen, WG | 2 |
| Zhang, B | 2 |
| Lee, DR | 2 |
| Ampah, SB | 2 |
| Sobol, SE | 2 |
| Cook-Sather, SD | 2 |
| Shen, L | 1 |
| Wu, J | 2 |
| Xiao, Q | 1 |
| Hong, M | 1 |
| Wang, S | 1 |
| Wang, J | 1 |
| Luo, Q | 1 |
| Lin, X | 1 |
| Lian, J | 1 |
| Xu, Y | 1 |
| Guo, G | 1 |
| Amin, SM | 1 |
| Hasanin, A | 1 |
| ElSayed, OS | 1 |
| Mostafa, M | 1 |
| Khaled, D | 1 |
| Arafa, AS | 1 |
| Hassan, A | 1 |
| Liu, D | 1 |
| Lyu, J | 1 |
| Zhao, H | 1 |
| An, Y | 1 |
| Zhong, Q | 1 |
| Qu, X | 1 |
| Xu, C | 1 |
| Liu, J | 1 |
| Yuan, X | 1 |
| Kim, KM | 1 |
| Lee, KH | 1 |
| Kim, YH | 1 |
| Ko, MJ | 1 |
| Jung, JW | 1 |
| Kang, E | 1 |
| Ydemann, M | 1 |
| Nielsen, BN | 1 |
| Wetterslev, J | 1 |
| Henneberg, S | 1 |
| Lauritsen, T | 1 |
| Steen, N | 1 |
| Edström, B | 1 |
| Afshari, A | 1 |
| Moore, AD | 1 |
| Anghelescu, DL | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Midazolam Effect on Agitation Postnasal Surgery: A Double Blinded Randomized Controlled Trial[NCT05165914] | 100 participants (Actual) | Interventional | 2021-05-27 | Completed | |||
| Does Intraoperative Clonidine Reduce Post Operative Agitation in Children Anaesthetised With Sevoflurane? A RCT Including Pharmacokinetic Investigation.[NCT02361476] | Phase 4 | 379 participants (Actual) | Interventional | 2015-01-31 | Completed | ||
| Clonidine for Tourniquet-related Pain in Children: A Pilot Study[NCT04564430] | Phase 4 | 20 participants (Anticipated) | Interventional | 2021-03-01 | Recruiting | ||
| Effect of Different Administrations of Propofol on Emergence Agitation in Preschool Children Undergoing Ambulatory Surgery[NCT05420402] | 168 participants (Anticipated) | Interventional | 2022-08-01 | Active, not recruiting | |||
| Investigation of the DNA Methylation Profile in Children Who Presented Emergence Delirium[NCT03787849] | 175 participants (Actual) | Interventional | 2018-09-24 | Completed | |||
| Effectivity of 0.5 mg/kg Propofol in the End of Anesthesia to Reduce the Incidence of Postanesthetic Emergence Agitation in Pediatric Patients Under General Inhalation Anesthesia[NCT03528954] | 54 participants (Actual) | Interventional | 2018-05-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Amount used (NCT02361476)
Timeframe: Recorded during the stay in the postoperative recovery room
| Intervention | mg morphine equivalents (Mean) |
|---|---|
| Intervention | 0.46 |
| Placebo | 0.7 |
Time to administration (NCT02361476)
Timeframe: recovery room
| Intervention | MEDIAN time (min) to administration (Median) |
|---|---|
| Intervention | 105 |
| Placebo | 60 |
"Pain score used:~FLACC score = Face, Legs, Activity, Cry, Consolability Score ranges from 0 to 10 (severity increases with increasing score) Pain is FLACC score more than 3" (NCT02361476)
Timeframe: recovery room - hours
| Intervention | Pain Score (Mean) |
|---|---|
| Intervention | 1.57 |
| Placebo | 2.45 |
Measured by Watchae Scale (score 1-4), scores 1-2 = no agitation and scores 3-4 = agitated (NCT02361476)
Timeframe: 1 day
| Intervention | participants with agitation (Number) |
|---|---|
| Intervention | 46 |
| Placebo | 86 |
(NCT02361476)
Timeframe: from intervention to discharge from the recovery room
| Intervention | participants (Number) | ||
|---|---|---|---|
| adverse events | serious adverse events | Treated for low blood pressure | |
| Intervention | 0 | 2 | 0 |
| Placebo | 5 | 2 | 0 |
1 review available for fentanyl and Agitated Emergence
| Article | Year |
|---|---|
Emergence Delirium in Pediatric Anesthesia.
Topics: Anesthetics, Inhalation; Child; Child, Preschool; Clonidine; Desflurane; Dexmedetomidine; Emergence | 2017 |
Emergence Delirium in Pediatric Anesthesia.
Topics: Anesthetics, Inhalation; Child; Child, Preschool; Clonidine; Desflurane; Dexmedetomidine; Emergence | 2017 |
Emergence Delirium in Pediatric Anesthesia.
Topics: Anesthetics, Inhalation; Child; Child, Preschool; Clonidine; Desflurane; Dexmedetomidine; Emergence | 2017 |
Emergence Delirium in Pediatric Anesthesia.
Topics: Anesthetics, Inhalation; Child; Child, Preschool; Clonidine; Desflurane; Dexmedetomidine; Emergence | 2017 |
Emergence Delirium in Pediatric Anesthesia.
Topics: Anesthetics, Inhalation; Child; Child, Preschool; Clonidine; Desflurane; Dexmedetomidine; Emergence | 2017 |
Emergence Delirium in Pediatric Anesthesia.
Topics: Anesthetics, Inhalation; Child; Child, Preschool; Clonidine; Desflurane; Dexmedetomidine; Emergence | 2017 |
Emergence Delirium in Pediatric Anesthesia.
Topics: Anesthetics, Inhalation; Child; Child, Preschool; Clonidine; Desflurane; Dexmedetomidine; Emergence | 2017 |
Emergence Delirium in Pediatric Anesthesia.
Topics: Anesthetics, Inhalation; Child; Child, Preschool; Clonidine; Desflurane; Dexmedetomidine; Emergence | 2017 |
Emergence Delirium in Pediatric Anesthesia.
Topics: Anesthetics, Inhalation; Child; Child, Preschool; Clonidine; Desflurane; Dexmedetomidine; Emergence | 2017 |
Emergence Delirium in Pediatric Anesthesia.
Topics: Anesthetics, Inhalation; Child; Child, Preschool; Clonidine; Desflurane; Dexmedetomidine; Emergence | 2017 |
Emergence Delirium in Pediatric Anesthesia.
Topics: Anesthetics, Inhalation; Child; Child, Preschool; Clonidine; Desflurane; Dexmedetomidine; Emergence | 2017 |
Emergence Delirium in Pediatric Anesthesia.
Topics: Anesthetics, Inhalation; Child; Child, Preschool; Clonidine; Desflurane; Dexmedetomidine; Emergence | 2017 |
Emergence Delirium in Pediatric Anesthesia.
Topics: Anesthetics, Inhalation; Child; Child, Preschool; Clonidine; Desflurane; Dexmedetomidine; Emergence | 2017 |
Emergence Delirium in Pediatric Anesthesia.
Topics: Anesthetics, Inhalation; Child; Child, Preschool; Clonidine; Desflurane; Dexmedetomidine; Emergence | 2017 |
Emergence Delirium in Pediatric Anesthesia.
Topics: Anesthetics, Inhalation; Child; Child, Preschool; Clonidine; Desflurane; Dexmedetomidine; Emergence | 2017 |
Emergence Delirium in Pediatric Anesthesia.
Topics: Anesthetics, Inhalation; Child; Child, Preschool; Clonidine; Desflurane; Dexmedetomidine; Emergence | 2017 |
9 trials available for fentanyl and Agitated Emergence
| Article | Year |
|---|---|
Intraoperative use of low-dose dexmedetomidine for the prevention of emergence agitation following general anaesthesia in elderly patients: a randomized controlled trial.
Topics: Aged; Anesthesia Recovery Period; Anesthesia, General; Dexmedetomidine; Double-Blind Method; Emergen | 2022 |
Emergence agitation in paediatric day case surgery: A randomised, single-blinded study comparing narcotrend and heart rate variability with standard monitoring.
Topics: Anesthesia Recovery Period; Anesthetics, Inhalation; Child; Child, Preschool; Emergence Delirium; Fe | 2022 |
Atomised intranasal dexmedetomidine versus oral melatonin in prevention of emergence delirium in children undergoing ophthalmic surgery with sevoflurane: A randomised double-blind study.
Topics: Child; Dexmedetomidine; Double-Blind Method; Emergence Delirium; Fentanyl; Humans; Hypnotics and Sed | 2022 |
Comparison of the hemodynamic effects of opioid-based versus lidocaine-based induction of anesthesia with propofol in older adults: a randomized controlled trial.
Topics: Aged; Analgesics, Opioid; Anesthesia, General; Anesthetics, Intravenous; Emergence Delirium; Fentany | 2023 |
The influence of analgesic-based sedation protocols on delirium and outcomes in critically ill patients: A randomized controlled trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Critical Illness; Deep Sedation; Emergence Delirium; Fem | 2017 |
Effect of preoperative visiting operation room on emergence agitation in preschool children under sevoflurane anesthesia.
Topics: Anesthesia Recovery Period; Anesthesia, General; Anesthetics, Inhalation; Child; Child, Preschool; E | 2018 |
Effects of dexmedetomidine on emergence delirium in pediatric cardiac surgery.
Topics: Anesthesia, General; Anesthetics, Inhalation; Cardiac Surgical Procedures; Child; Child, Preschool; | 2017 |
Comparison of effects of intravenous midazolam and ketamine on emergence agitation in children: Randomized controlled trial.
Topics: Anesthesia Recovery Period; Anesthesia, General; Anesthetics, Dissociative; Anesthetics, Inhalation; | 2016 |
Effect of clonidine to prevent agitation in children after sevoflurane anaesthesia: a randomised placebo controlled multicentre trial.
Topics: Adjuvants, Anesthesia; Adrenergic alpha-2 Receptor Agonists; Anesthesia; Anesthetics, Inhalation; Ch | 2016 |
Effect of clonidine to prevent agitation in children after sevoflurane anaesthesia: a randomised placebo controlled multicentre trial.
Topics: Adjuvants, Anesthesia; Adrenergic alpha-2 Receptor Agonists; Anesthesia; Anesthetics, Inhalation; Ch | 2016 |
Effect of clonidine to prevent agitation in children after sevoflurane anaesthesia: a randomised placebo controlled multicentre trial.
Topics: Adjuvants, Anesthesia; Adrenergic alpha-2 Receptor Agonists; Anesthesia; Anesthetics, Inhalation; Ch | 2016 |
Effect of clonidine to prevent agitation in children after sevoflurane anaesthesia: a randomised placebo controlled multicentre trial.
Topics: Adjuvants, Anesthesia; Adrenergic alpha-2 Receptor Agonists; Anesthesia; Anesthetics, Inhalation; Ch | 2016 |
2 other studies available for fentanyl and Agitated Emergence
| Article | Year |
|---|---|
Middle Ear Condition at the Time of Pediatric Myringotomy Tube Placement: Pain Associations Following Intraoperative Fentanyl/Ketorolac and Seasonal Variation.
Topics: Child; Double-Blind Method; Ear, Middle; Emergence Delirium; Fentanyl; Humans; Ketorolac; Oxycodone; | 2023 |
Middle Ear Condition at the Time of Pediatric Myringotomy Tube Placement: Pain Associations Following Intraoperative Fentanyl/Ketorolac and Seasonal Variation.
Topics: Child; Double-Blind Method; Ear, Middle; Emergence Delirium; Fentanyl; Humans; Ketorolac; Oxycodone; | 2023 |
Middle Ear Condition at the Time of Pediatric Myringotomy Tube Placement: Pain Associations Following Intraoperative Fentanyl/Ketorolac and Seasonal Variation.
Topics: Child; Double-Blind Method; Ear, Middle; Emergence Delirium; Fentanyl; Humans; Ketorolac; Oxycodone; | 2023 |
Middle Ear Condition at the Time of Pediatric Myringotomy Tube Placement: Pain Associations Following Intraoperative Fentanyl/Ketorolac and Seasonal Variation.
Topics: Child; Double-Blind Method; Ear, Middle; Emergence Delirium; Fentanyl; Humans; Ketorolac; Oxycodone; | 2023 |
Association between ABO blood groups and postoperative pain in children after adenotonsillectomy: a prospective cohort study.
Topics: ABO Blood-Group System; Analgesics, Opioid; Double-Blind Method; Emergence Delirium; Fentanyl; Human | 2022 |