Page last updated: 2024-10-27

fentanyl and Adverse Drug Event

fentanyl has been researched along with Adverse Drug Event in 36 studies

Fentanyl: A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078)
fentanyl : A monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of N-phenyl-1-(2-phenylethyl)piperidin-4-amine with propanoic acid.

Research Excerpts

ExcerptRelevanceReference
" We evaluated the efficacy of sublingual fentanyl tablet (SLF) for the treatment of BTP in opioid-tolerant patients with chronic musculoskeletal pain with neuropathic component in terms of relief of pain intensity and assessed whether hypothetical pain relief impacts on quality of life (QoL)."9.20Efficacy and safety of sublingual fentanyl tablets for the management of breakthrough pain in patients with chronic musculoskeletal pain with neuropathic component: multicenter prospective study. ( Camba-Rodríguez, A; Cánovas-Martínez, L; Carceller-Ruiz, JJ; De la Iglesia-López, A; Díaz-Parada, P; Domínguez-Suárez, E; Freire-Vila, E; Iglesias, BG; Illodo-Miramontes, G; López-Ulloa, B, 2015)
"We performed a systematic review to evaluate the current evidence for the use of fentanyl for the relief of breathlessness."8.89Fentanyl for the relief of refractory breathlessness: a systematic review. ( Gaertner, J; Köskeroglu, P; Simon, ST; Voltz, R, 2013)
" placebo in the first 30 minutes after dosing (FBT provided an 83% probability of superior pain relief, ODT 66%, and OTFC 73% vs."6.49Efficacy of rapid-onset oral fentanyl formulations vs. oral morphine for cancer-related breakthrough pain: a meta-analysis of comparative trials. ( Bennett, MI; Fullarton, JR; Jandhyala, R, 2013)
"Adverse drug reactions were registered in 3%."5.48Fentanyl buccal tablet for breakthrough cancer pain in clinical practice: results of the non-interventional prospective study ErkentNIS. ( Gneist, M; Landthaler, R; Masel, EK; Watzke, HH, 2018)
"Guidelines tend to consider morphine and morphine-like opioids comparable and interchangeable in the treatment of chronic cancer pain, but individual responses can vary."5.22Are strong opioids equally effective and safe in the treatment of chronic cancer pain? A multicenter randomized phase IV 'real life' trial on the variability of response to opioids. ( Apolone, G; Azzarello, G; Bandieri, E; Caraceni, A; Cavanna, L; Corli, O; Crispino, C; Di Gregorio, R; Dragani, TA; Floriani, I; Galli, F; Gamucci, T; Greco, MT; Iorno, V; Kaasa, S; Lipari, G; Luzzani, M; Montanari, M; Pacchioni, M; Pavesi, L; Reale, C; Roberto, A; Valenti, D, 2016)
" We evaluated the efficacy of sublingual fentanyl tablet (SLF) for the treatment of BTP in opioid-tolerant patients with chronic musculoskeletal pain with neuropathic component in terms of relief of pain intensity and assessed whether hypothetical pain relief impacts on quality of life (QoL)."5.20Efficacy and safety of sublingual fentanyl tablets for the management of breakthrough pain in patients with chronic musculoskeletal pain with neuropathic component: multicenter prospective study. ( Camba-Rodríguez, A; Cánovas-Martínez, L; Carceller-Ruiz, JJ; De la Iglesia-López, A; Díaz-Parada, P; Domínguez-Suárez, E; Freire-Vila, E; Iglesias, BG; Illodo-Miramontes, G; López-Ulloa, B, 2015)
"We performed a systematic review to evaluate the current evidence for the use of fentanyl for the relief of breathlessness."4.89Fentanyl for the relief of refractory breathlessness: a systematic review. ( Gaertner, J; Köskeroglu, P; Simon, ST; Voltz, R, 2013)
"Adjusting for covariates, both the total number of drug seizures and amount of cocaine seized (in dosage units per capita) positively predicted next-year opioid- and fentanyl-involved fatal overdose rates."4.12Supply-side predictors of fatal drug overdose in the Washington/Baltimore HIDTA region: 2016-2020. ( Bates, R; Carr, T; Lowder, EM; Peppard, L; Zhou, W, 2022)
"The incidence of delirium was compared among 114 patients who had started morphine, oxycodone, or fentanyl injection at Shizuoka Cancer Center between June 2012 and September 2014."3.85Incidence of Delirium Among Patients Having Cancer Injected With Different Opioids for the First Time. ( Ishikawa, H; Matsumoto, T; Mori, K; Omae, K; Osaka, I; Sato, T; Shino, M; Tanaka, R, 2017)
"The incidence of myoclonus was significantly lower in the nalmefene group (8."3.30Low-dose nalmefene pretreatment reduces etomidate-induced myoclonus: A randomized, double-blind controlled trial. ( Cao, H; Dai, F; Liu, Y; Lu, H; Shan, G; Yin, D, 2023)
"Naloxone is the primary opioid overdose reversal agent, but concern has been raised that naloxone is not efficacious against the pervasive illicit high potency opioids (i."2.82Treatment of opioid overdose: current approaches and recent advances. ( Britch, SC; Walsh, SL, 2022)
" Since information about potency and lethal dosage are frequently unknown, it is important to identify the new trends for further investigation on therapeutic use, toxicity and fatal doses, and implement public health measures."2.72A 2017-2019 Update on Acute Intoxications and Fatalities from Illicit Fentanyl and Analogs. ( Brunetti, P; Busardò, FP; Carlier, J; Giorgetti, R; Lo Faro, AF; Pirani, F, 2021)
" placebo in the first 30 minutes after dosing (FBT provided an 83% probability of superior pain relief, ODT 66%, and OTFC 73% vs."2.49Efficacy of rapid-onset oral fentanyl formulations vs. oral morphine for cancer-related breakthrough pain: a meta-analysis of comparative trials. ( Bennett, MI; Fullarton, JR; Jandhyala, R, 2013)
" Safe supply programs are required now more than ever to address the high rate of drug toxicity overdose deaths caused by illicit fentanyl and its analogues."1.72Investigating opioid preference to inform safe supply services: A cross sectional study. ( Buxton, JA; Ferguson, M; Lock, K; Papamihali, K; Parmar, A; Weng, A, 2022)
"Main adverse drug events were nausea and vomiting, somnolence, and confusion."1.72Tolerance of Fentanyl Pectin Nasal Spray for Procedural Pain in Geriatric Patients. ( Baudrant, M; Bedouch, P; Cracowski, JL; Drevet, S; Gavazzi, G; Gibert, P; Grevy, A; Maindet, C; Maljean, L; Mitha, N; Payen, M; Tiffet, T; Zerhouni, N, 2022)
" We sought to determine the risk of serious adverse events (SAEs) when oral azithromycin or intravenous/intramuscular fentanyl are used off-label compared to on-label in pediatric intensive care units (ICUs)."1.51Serious Adverse Events Associated with Off-Label Use of Azithromycin or Fentanyl in Children in Intensive Care Units: A Retrospective Chart Review. ( Avant, D; Doe, E; Fenn, NE; Lardieri, A; Lieu, P; McMahon, AW; Oshikoya, KA; Sood, BG; Taketomo, C; Van Driest, SL; Wharton, GT; Yen, L, 2019)
"Adverse drug reactions were registered in 3%."1.48Fentanyl buccal tablet for breakthrough cancer pain in clinical practice: results of the non-interventional prospective study ErkentNIS. ( Gneist, M; Landthaler, R; Masel, EK; Watzke, HH, 2018)
"57% of patients having complications (52 patients having 60 adverse events)."1.37Safety of intravenous sedation administered by the operating oral surgeon: the second 7 years of office practice. ( Rodgers, MS; Rodgers, SF, 2011)
"5 million adverse drug reaction (ADR) reports for 8620 drugs/biologics that are listed for 1191 Coding Symbols for Thesaurus of Adverse Reaction (COSTAR) terms of adverse effects."1.32Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. ( Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL, 2004)

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-19901 (2.78)18.7374
1990's0 (0.00)18.2507
2000's4 (11.11)29.6817
2010's18 (50.00)24.3611
2020's13 (36.11)2.80

Authors

AuthorsStudies
Matthews, EJ1
Kruhlak, NL1
Weaver, JL1
Benz, RD1
Contrera, JF1
Liu, Z1
Shi, Q1
Ding, D1
Kelly, R1
Fang, H1
Tong, W1
Del Pozo, B1
Rich, JD1
Carroll, JJ1
Yeo, Y1
Johnson, R1
Heng, C1
Ferguson, M1
Parmar, A1
Papamihali, K1
Weng, A1
Lock, K1
Buxton, JA1
Britch, SC1
Walsh, SL1
Maljean, L1
Gavazzi, G1
Gibert, P1
Grevy, A1
Payen, M1
Zerhouni, N1
Tiffet, T1
Cracowski, JL1
Mitha, N1
Maindet, C1
Baudrant, M1
Bedouch, P1
Drevet, S1
Dyer, O1
Palamar, JJ1
Cottler, LB1
Goldberger, BA1
Severtson, SG1
Grundy, DJ1
Iwanicki, JL1
Ciccarone, D1
Lowder, EM1
Zhou, W1
Peppard, L1
Bates, R1
Carr, T1
Ellefsen, KN1
Smith, CR1
Taylor, EA1
Hall, BJ1
Chatterton, CN1
Handy, RP1
Shan, G1
Lu, H1
Dai, F1
Liu, Y1
Yin, D1
Cao, H1
Zhong, L1
Li, H1
Zhao, B1
Brunetti, P1
Pirani, F1
Carlier, J1
Giorgetti, R1
Busardò, FP1
Lo Faro, AF1
Fleet, JA1
Jones, M1
Belan, I1
Masel, EK1
Landthaler, R1
Gneist, M1
Watzke, HH1
Breivik, H1
Karila, L1
Marillier, M1
Chaumette, B1
Billieux, J1
Franchitto, N1
Benyamina, A1
Oshikoya, KA1
Wharton, GT1
Avant, D1
Van Driest, SL1
Fenn, NE1
Lardieri, A1
Doe, E1
Sood, BG1
Taketomo, C1
Lieu, P1
Yen, L1
McMahon, AW1
Simon, ST1
Köskeroglu, P1
Gaertner, J1
Voltz, R1
Cuervo Pinna, MÁ1
Cánovas-Martínez, L1
Carceller-Ruiz, JJ1
Díaz-Parada, P1
Illodo-Miramontes, G1
Freire-Vila, E1
De la Iglesia-López, A1
Iglesias, BG1
López-Ulloa, B1
Domínguez-Suárez, E1
Camba-Rodríguez, A1
Shastay, A1
Corli, O1
Floriani, I1
Roberto, A1
Montanari, M1
Galli, F1
Greco, MT1
Caraceni, A1
Kaasa, S1
Dragani, TA1
Azzarello, G1
Luzzani, M1
Cavanna, L1
Bandieri, E1
Gamucci, T1
Lipari, G1
Di Gregorio, R1
Valenti, D1
Reale, C1
Pavesi, L1
Iorno, V1
Crispino, C1
Pacchioni, M1
Apolone, G1
Tanaka, R1
Ishikawa, H1
Sato, T1
Shino, M1
Matsumoto, T1
Mori, K1
Omae, K1
Osaka, I1
Mora, AG1
Ganem, VJ1
Ervin, AT1
Maddry, JK1
Bebarta, VS1
Sande, TA1
Laird, BJ1
Fallon, MT1
Chrysostomou, C1
Sanchez De Toledo, J1
Avolio, T1
Motoa, MV1
Berry, D1
Morell, VO1
Orr, R1
Munoz, R1
Jacobsen, R1
Møldrup, C1
Christrup, L1
Stammschulte, T1
Brune, K1
Rodgers, SF1
Rodgers, MS1
Jenerowicz, D1
Polańska, A1
Olek-Hrab, K1
Silny, W1
Jandhyala, R1
Fullarton, JR1
Bennett, MI1
Stuerenburg, HJ1
Claassen, J1
Eggers, C1
Hansen, HC1
Ndiritu, CG1
Enos, LR1

Clinical Trials (5)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Morphine or Fentanyl for Refractory Dyspnea in COPD[NCT03834363]Phase 460 participants (Anticipated)Interventional2019-11-15Recruiting
An Observational Study to Assess the Efficacy, Safety, and Tolerability of Abstral Oral Disintegrating Tablet (ODT) for the Management of Breakthrough Cancer Pain in Korean Cancer Patients[NCT03895762]143 participants (Actual)Observational2017-07-04Completed
RCT Comparing the Analgesic Efficacy of 4 Therapeutic Strategies Based on 4 Different Major Opioids (Fentanyl, Oxycodone, Buprenorphine vs Morphine) in Cancer Patients With Moderate/Severe Pain, at the Moment of Starting 3rd Step of WHO Analgesic Ladder.[NCT01809106]Phase 4518 participants (Actual)Interventional2011-04-30Completed
Pharmacokinetic-pharmacodynamic Analysis for Dosing Strategy and Evaluation of Safety and Efficacy of Dexmedetomidine in Children[NCT04027829]Phase 213 participants (Actual)Interventional2019-08-14Completed
Efficacy of Injectable Fentanyl in Sublingual Route Versus Oral Morphine Syrup for Breakthrough Pain in Gynecologic Cancer Patients With Chronic Cancer Pain : A Randomized Double Blind Controlled Trial[NCT05037539]Phase 1/Phase 220 participants (Actual)Interventional2021-06-15Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Proportion of Full-responder

Evaluation of the proportion of subjects who report full analgesia (full responders: FR). FR is operationally defined as a patient with a P.I.D. =/> 30% from visit 6 and visit 1 (NRS 0 to 10). (NCT01809106)
Timeframe: 28 days

Interventionparticipants (Number)
Morphine89
Oxycodone90
Buprenorphine95
Fentanyl88

Proportion of Non-Responder (NR) Participants

"Evaluation of the proportion of Non-Responder (NR) participants. NR correspond to the subjects who do not report any analgesic effects, with a P.I.D. (pain intensity difference) from visit 6 and visit 1 =/< 0%, (using a 0-10 NRS ). It includes the situations of average pain intensity stable or worsened at day 28 compared with baseline values." (NCT01809106)
Timeframe: 28 days

Interventionparticipants (Number)
Morphine14
Oxycodone18
Buprenorphine14
Fentanyl11

The Opioid Escalation Index

The proportion of subjects with an increase of opioid daily dose > 5% compared with the basal dosage (OEI%). (NCT01809106)
Timeframe: 28 days

Interventionparticipants (Number)
Morphine13
Oxycodone24
Buprenorphine18
Fentanyl45

Reviews

8 reviews available for fentanyl and Adverse Drug Event

ArticleYear
Treatment of opioid overdose: current approaches and recent advances.
    Psychopharmacology, 2022, Volume: 239, Issue:7

    Topics: Analgesics, Opioid; Drug Overdose; Drug-Related Side Effects and Adverse Reactions; Fentanyl; Humans

2022
Fentanyl concentrations in ligated femoral blood in the presence and absence of NPS benzodiazepine drugs. A review of over 1250 benzo-dope / fentanyl toxicity cases in Alberta, Canada.
    Forensic science international, 2023, Volume: 350

    Topics: Alberta; Analgesics, Opioid; Autopsy; Drug Overdose; Drug-Related Side Effects and Adverse Reactions

2023
A 2017-2019 Update on Acute Intoxications and Fatalities from Illicit Fentanyl and Analogs.
    Journal of analytical toxicology, 2021, Jul-10, Volume: 45, Issue:6

    Topics: Analgesics, Opioid; Drug-Related Side Effects and Adverse Reactions; Fentanyl; Humans; Substance-Rel

2021
New synthetic opioids: Part of a new addiction landscape.
    Neuroscience and biobehavioral reviews, 2019, Volume: 106

    Topics: Analgesics, Opioid; Behavioral Symptoms; Drug-Related Side Effects and Adverse Reactions; Fentanyl;

2019
Fentanyl for the relief of refractory breathlessness: a systematic review.
    Journal of pain and symptom management, 2013, Volume: 46, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Chronic Disease; Drug-Related Side E

2013
The use of opioids in cancer patients with renal impairment-a systematic review.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2017, Volume: 25, Issue:2

    Topics: Analgesics, Opioid; Drug-Related Side Effects and Adverse Reactions; Fentanyl; Humans; Neoplasms; Pa

2017
Skin hypersensitivity reactions to transdermal therapeutic systems--still an important clinical problem.
    Ginekologia polska, 2012, Volume: 83, Issue:1

    Topics: Administration, Cutaneous; Dermatitis, Contact; Drug Delivery Systems; Drug Eruptions; Drug-Related

2012
Efficacy of rapid-onset oral fentanyl formulations vs. oral morphine for cancer-related breakthrough pain: a meta-analysis of comparative trials.
    Journal of pain and symptom management, 2013, Volume: 46, Issue:4

    Topics: Administration, Oral; Analgesics, Opioid; Breakthrough Pain; Causality; Comorbidity; Controlled Clin

2013

Trials

4 trials available for fentanyl and Adverse Drug Event

ArticleYear
Low-dose nalmefene pretreatment reduces etomidate-induced myoclonus: A randomized, double-blind controlled trial.
    Medicine, 2023, Sep-08, Volume: 102, Issue:36

    Topics: Anesthesia, General; Cough; Drug-Related Side Effects and Adverse Reactions; Etomidate; Fentanyl; Hu

2023
Taking the alternative route: Women's experience of intranasal fentanyl, subcutaneous fentanyl or intramuscular pethidine for labour analgesia.
    Midwifery, 2017, Volume: 53

    Topics: Administration, Intranasal; Adult; Analgesics; Drug-Related Side Effects and Adverse Reactions; Fema

2017
Efficacy and safety of sublingual fentanyl tablets for the management of breakthrough pain in patients with chronic musculoskeletal pain with neuropathic component: multicenter prospective study.
    Clinical drug investigation, 2015, Volume: 35, Issue:3

    Topics: Administration, Sublingual; Adult; Aged; Aged, 80 and over; Breakthrough Pain; Drug-Related Side Eff

2015
Are strong opioids equally effective and safe in the treatment of chronic cancer pain? A multicenter randomized phase IV 'real life' trial on the variability of response to opioids.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2016, Volume: 27, Issue:6

    Topics: Adult; Aged; Analgesics, Opioid; Cancer Pain; Drug-Related Side Effects and Adverse Reactions; Femal

2016
Are strong opioids equally effective and safe in the treatment of chronic cancer pain? A multicenter randomized phase IV 'real life' trial on the variability of response to opioids.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2016, Volume: 27, Issue:6

    Topics: Adult; Aged; Analgesics, Opioid; Cancer Pain; Drug-Related Side Effects and Adverse Reactions; Femal

2016
Are strong opioids equally effective and safe in the treatment of chronic cancer pain? A multicenter randomized phase IV 'real life' trial on the variability of response to opioids.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2016, Volume: 27, Issue:6

    Topics: Adult; Aged; Analgesics, Opioid; Cancer Pain; Drug-Related Side Effects and Adverse Reactions; Femal

2016
Are strong opioids equally effective and safe in the treatment of chronic cancer pain? A multicenter randomized phase IV 'real life' trial on the variability of response to opioids.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2016, Volume: 27, Issue:6

    Topics: Adult; Aged; Analgesics, Opioid; Cancer Pain; Drug-Related Side Effects and Adverse Reactions; Femal

2016

Other Studies

24 other studies available for fentanyl and Adverse Drug Event

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Dru

2004
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
    PLoS computational biology, 2011, Volume: 7, Issue:12

    Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da

2011
Reports of accidental fentanyl overdose among police in the field: Toward correcting a harmful culture-bound syndrome.
    The International journal on drug policy, 2022, Volume: 100

    Topics: Analgesics, Opioid; Drug Overdose; Drug-Related Side Effects and Adverse Reactions; Fentanyl; Humans

2022
The Public Health Approach to the Worsening Opioid Crisis in the United States Calls for Harm Reduction Strategies to Mitigate the Harm From Opioid Addiction and Overdose Deaths.
    Military medicine, 2022, 08-25, Volume: 187, Issue:9-10

    Topics: Analgesics, Opioid; Drug Overdose; Drug-Related Side Effects and Adverse Reactions; Fentanyl; Harm R

2022
Investigating opioid preference to inform safe supply services: A cross sectional study.
    The International journal on drug policy, 2022, Volume: 101

    Topics: Adult; Analgesics, Opioid; British Columbia; Cross-Sectional Studies; Drug Overdose; Drug-Related Si

2022
Tolerance of Fentanyl Pectin Nasal Spray for Procedural Pain in Geriatric Patients.
    Journal of the American Medical Directors Association, 2022, Volume: 23, Issue:6

    Topics: Aged; Analgesics, Opioid; Drug-Related Side Effects and Adverse Reactions; Fentanyl; Humans; Nasal S

2022
Ohio doctor is acquitted of murdering 14 intensive care patients with fentanyl overdoses.
    BMJ (Clinical research ed.), 2022, 04-25, Volume: 377

    Topics: Critical Care; Drug Overdose; Drug-Related Side Effects and Adverse Reactions; Fentanyl; Humans; Ohi

2022
Trends in characteristics of fentanyl-related poisonings in the United States, 2015-2021.
    The American journal of drug and alcohol abuse, 2022, 07-04, Volume: 48, Issue:4

    Topics: Adolescent; Adult; Analgesics, Opioid; Drug Overdose; Drug-Related Side Effects and Adverse Reaction

2022
Supply-side predictors of fatal drug overdose in the Washington/Baltimore HIDTA region: 2016-2020.
    The International journal on drug policy, 2022, Volume: 110

    Topics: Analgesics, Opioid; Drug Overdose; Drug Trafficking; Drug-Related Side Effects and Adverse Reactions

2022
Emergence of fentanyl-related deaths in Travis County, Texas and surrounding areas: A retrospective review of postmortem fentanyl-related drug toxicities from 2020 to 2022.
    Journal of forensic sciences, 2023, Volume: 68, Issue:5

    Topics: Alprazolam; Analgesics, Opioid; Drug Overdose; Drug-Related Side Effects and Adverse Reactions; Fent

2023
Comparison of Ketamine Alone and Subanesthetic Dose of Ketamine-Fentanyl for Regional Anesthesia in Children.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2020, Volume: 30, Issue:1

    Topics: Administration, Intravenous; Analgesia; Anesthesia, Intravenous; Child; Child, Preschool; Drug-Relat

2020
Fentanyl buccal tablet for breakthrough cancer pain in clinical practice: results of the non-interventional prospective study ErkentNIS.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2018, Volume: 26, Issue:2

    Topics: Administration, Buccal; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Breakthrough Pain; Cance

2018
A case-history illustrates importance of knowledge of drug-interactions when pain-patients are prescribed non-pain drugs for co-morbidities.
    Scandinavian journal of pain, 2017, Volume: 17

    Topics: Aged; Comorbidity; Diclofenac; Drug Interactions; Drug-Related Side Effects and Adverse Reactions; F

2017
Serious Adverse Events Associated with Off-Label Use of Azithromycin or Fentanyl in Children in Intensive Care Units: A Retrospective Chart Review.
    Paediatric drugs, 2019, Volume: 21, Issue:1

    Topics: Administration, Intravenous; Administration, Oral; Adolescent; Analgesics, Opioid; Anti-Bacterial Ag

2019
A randomized crossover clinical trial to evaluate the efficacy of oral transmucosal fentanyl citrate in the treatment of dyspnea on exertion in patients with advanced cancer.
    Journal of pain and symptom management, 2014, Volume: 47, Issue:6

    Topics: Drug-Related Side Effects and Adverse Reactions; Dyspnea; Female; Fentanyl; Humans; Male; Patient Sa

2014
Actiq Is Not for Sore Throats!
    Home healthcare now, 2016, Volume: 34, Issue:3

    Topics: Administration, Topical; Drug-Related Side Effects and Adverse Reactions; Female; Fentanyl; Humans;

2016
Incidence of Delirium Among Patients Having Cancer Injected With Different Opioids for the First Time.
    The American journal of hospice & palliative care, 2017, Volume: 34, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Cancer Pain; Delirium; Drug-Related Side Effects

2017
En Route Use of Analgesics in Nonintubated, Critically Ill Patients Transported by U.S. Air Force Critical Care Air Transport Teams.
    Military medicine, 2016, Volume: 181, Issue:5 Suppl

    Topics: Adult; Aerospace Medicine; Afghan Campaign 2001-; Air Ambulances; Analgesics; Critical Care; Critica

2016
Dexmedetomidine use in a pediatric cardiac intensive care unit: can we use it in infants after cardiac surgery?
    Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2009, Volume: 10, Issue:6

    Topics: Age Factors; Analgesics, Non-Narcotic; Analgesics, Opioid; Dexmedetomidine; Dose-Response Relationsh

2009
Danish pain specialists' rationales behind the choice of fentanyl transdermal patches and oral transmucosal systems--a delphi study.
    Pain medicine (Malden, Mass.), 2009, Volume: 10, Issue:8

    Topics: Administration, Cutaneous; Administration, Oral; Analgesics, Opioid; Data Collection; Decision Suppo

2009
[Drug safety problems in association with the use of opioid containing patches for the management of pain].
    Deutsche medizinische Wochenschrift (1946), 2010, Volume: 135, Issue:17

    Topics: Administration, Cutaneous; Adult; Aged, 80 and over; Analgesics, Opioid; Drug Overdose; Drug-Related

2010
Safety of intravenous sedation administered by the operating oral surgeon: the second 7 years of office practice.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2011, Volume: 69, Issue:10

    Topics: Adult; Aged; Ambulatory Surgical Procedures; Anesthesia, Dental; Anesthetics, Intravenous; Conscious

2011
Acute adverse reaction to fentanyl in a 55 year old man.
    Journal of neurology, neurosurgery, and psychiatry, 2000, Volume: 69, Issue:2

    Topics: Cerebral Angiography; Chest Pain; Coma; Confusion; Diagnosis, Differential; Drug-Related Side Effect

2000
Adverse reactions to drugs in a veterinary hospital.
    Journal of the American Veterinary Medical Association, 1977, Aug-15, Volume: 171, Issue:4

    Topics: Amphotericin B; Anaphylaxis; Animals; Cat Diseases; Cats; Cattle; Cattle Diseases; Chloral Hydrate;

1977