fentanyl has been researched along with Adrenal Insufficiency in 7 studies
Fentanyl: A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078)
fentanyl : A monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of N-phenyl-1-(2-phenylethyl)piperidin-4-amine with propanoic acid.
Adrenal Insufficiency: Conditions in which the production of adrenal CORTICOSTEROIDS falls below the requirement of the body. Adrenal insufficiency can be caused by defects in the ADRENAL GLANDS, the PITUITARY GLAND, or the HYPOTHALAMUS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We retrospectively studied the clinical characteristics of infants (<29 weeks' gestation) before (n=26) and after (n=35) implementing the following practice changes: stress reduction, conservative replacement of thyroid hormone, positive antenatal glucocorticoid administration, sedation with fentanyl (<7 days after birth), and hydrocortisone therapy for hypotension." | 3.81 | Increased Incidence of Late-Onset Circulatory Collapse after Changing Clinical Practice: A Retrospective Investigation of Causative Factors. ( Akaba, K; Saito, E; Shimokaze, T, 2015) |
| "We report on a 64-year-old patient in whom fentanyl therapy was found to be responsible for the induction of secondary adrenal insufficiency as clearly demonstrated by re-exposure." | 3.75 | Secondary adrenal insufficiency due to opiate therapy - another differential diagnosis worth consideration. ( Brändle, M; Greminger, P; Schimke, KE, 2009) |
| "Opioid-induced hypoadrenalism is likely an under-recognised clinical entity with potentially serious adverse patient outcomes." | 1.51 | Opioid-induced hypoadrenalism resulting in fasting hypoglycaemia. ( Clarke, AJ; Tabet, EJ; Twigg, SM, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (42.86) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Kondo, A | 1 |
| Murakami, T | 1 |
| Fujii, T | 1 |
| Tatsumi, M | 1 |
| Ueda-Sakane, Y | 1 |
| Ueda, Y | 1 |
| Yamauchi, I | 1 |
| Ogura, M | 1 |
| Taura, D | 1 |
| Inagaki, N | 1 |
| Tabet, EJ | 1 |
| Clarke, AJ | 1 |
| Twigg, SM | 1 |
| Shimokaze, T | 1 |
| Saito, E | 1 |
| Akaba, K | 1 |
| Schimke, KE | 1 |
| Greminger, P | 1 |
| Brändle, M | 1 |
| Mazul-Sunko, B | 1 |
| Resetic, J | 1 |
| Solter, M | 1 |
| Ivanec, Z | 1 |
| Oltmanns, KM | 1 |
| Fehm, HL | 1 |
| Peters, A | 1 |
| Wanscher, M | 1 |
| Tønnesen, E | 1 |
| Hüttel, M | 1 |
| Larsen, K | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Anesthesia for Upper Endoscopy and Colonoscopy in Cardiac Patients With Acute Anemia: Pretreatment With Low-dose Ketamine Can Reduce the Dose of Etomidate. A Randomized Clinical Trial.[NCT04857450] | 60 participants (Anticipated) | Interventional | 2020-11-20 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
7 other studies available for fentanyl and Adrenal Insufficiency
| Article | Year |
|---|---|
Opioid-induced adrenal insufficiency in transdermal fentanyl treatment: a revisited diagnosis in clinical setting.
Topics: Adrenal Insufficiency; Analgesics, Opioid; Constipation; Female; Fentanyl; Humans; Middle Aged; Neop | 2022 |
Opioid-induced hypoadrenalism resulting in fasting hypoglycaemia.
Topics: Adolescent; Adrenal Insufficiency; Analgesics, Opioid; Female; Fentanyl; Humans; Hypoglycemia; Trama | 2019 |
Increased Incidence of Late-Onset Circulatory Collapse after Changing Clinical Practice: A Retrospective Investigation of Causative Factors.
Topics: Adrenal Insufficiency; Female; Fentanyl; Gestational Age; Humans; Hydrocortisone; Hyponatremia; Hypo | 2015 |
Secondary adrenal insufficiency due to opiate therapy - another differential diagnosis worth consideration.
Topics: Adrenal Cortex Hormones; Adrenal Insufficiency; Analgesics, Opioid; Diagnosis, Differential; Fentany | 2009 |
Postoperative adrenal crisis in a patient with Schmidt syndrome (autoimmune polyglandular endocrinopathy type II).
Topics: Adrenal Insufficiency; Adult; Anesthetics, Intravenous; Anti-Inflammatory Agents; Antithyroid Agents | 2004 |
Chronic fentanyl application induces adrenocortical insufficiency.
Topics: Administration, Cutaneous; Adrenal Insufficiency; Anti-Inflammatory Agents; Drug Administration Sche | 2005 |
Etomidate infusion and adrenocortical function. A study in elective surgery.
Topics: Adrenal Cortex; Adrenal Insufficiency; Anesthetics; Cosyntropin; Drug Tolerance; Etomidate; Female; | 1985 |