fentanyl has been researched along with Adrenal Gland Hypofunction in 7 studies
Fentanyl: A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078)
fentanyl : A monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of N-phenyl-1-(2-phenylethyl)piperidin-4-amine with propanoic acid.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We retrospectively studied the clinical characteristics of infants (<29 weeks' gestation) before (n=26) and after (n=35) implementing the following practice changes: stress reduction, conservative replacement of thyroid hormone, positive antenatal glucocorticoid administration, sedation with fentanyl (<7 days after birth), and hydrocortisone therapy for hypotension." | 3.81 | Increased Incidence of Late-Onset Circulatory Collapse after Changing Clinical Practice: A Retrospective Investigation of Causative Factors. ( Akaba, K; Saito, E; Shimokaze, T, 2015) |
| "We report on a 64-year-old patient in whom fentanyl therapy was found to be responsible for the induction of secondary adrenal insufficiency as clearly demonstrated by re-exposure." | 3.75 | Secondary adrenal insufficiency due to opiate therapy - another differential diagnosis worth consideration. ( Brändle, M; Greminger, P; Schimke, KE, 2009) |
| "Opioid-induced hypoadrenalism is likely an under-recognised clinical entity with potentially serious adverse patient outcomes." | 1.51 | Opioid-induced hypoadrenalism resulting in fasting hypoglycaemia. ( Clarke, AJ; Tabet, EJ; Twigg, SM, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (42.86) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Kondo, A | 1 |
| Murakami, T | 1 |
| Fujii, T | 1 |
| Tatsumi, M | 1 |
| Ueda-Sakane, Y | 1 |
| Ueda, Y | 1 |
| Yamauchi, I | 1 |
| Ogura, M | 1 |
| Taura, D | 1 |
| Inagaki, N | 1 |
| Tabet, EJ | 1 |
| Clarke, AJ | 1 |
| Twigg, SM | 1 |
| Shimokaze, T | 1 |
| Saito, E | 1 |
| Akaba, K | 1 |
| Schimke, KE | 1 |
| Greminger, P | 1 |
| Brändle, M | 1 |
| Mazul-Sunko, B | 1 |
| Resetic, J | 1 |
| Solter, M | 1 |
| Ivanec, Z | 1 |
| Oltmanns, KM | 1 |
| Fehm, HL | 1 |
| Peters, A | 1 |
| Wanscher, M | 1 |
| Tønnesen, E | 1 |
| Hüttel, M | 1 |
| Larsen, K | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Anesthesia for Upper Endoscopy and Colonoscopy in Cardiac Patients With Acute Anemia: Pretreatment With Low-dose Ketamine Can Reduce the Dose of Etomidate. A Randomized Clinical Trial.[NCT04857450] | 60 participants (Anticipated) | Interventional | 2020-11-20 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
7 other studies available for fentanyl and Adrenal Gland Hypofunction
| Article | Year |
|---|---|
Opioid-induced adrenal insufficiency in transdermal fentanyl treatment: a revisited diagnosis in clinical setting.
Topics: Adrenal Insufficiency; Analgesics, Opioid; Constipation; Female; Fentanyl; Humans; Middle Aged; Neop | 2022 |
Opioid-induced hypoadrenalism resulting in fasting hypoglycaemia.
Topics: Adolescent; Adrenal Insufficiency; Analgesics, Opioid; Female; Fentanyl; Humans; Hypoglycemia; Trama | 2019 |
Increased Incidence of Late-Onset Circulatory Collapse after Changing Clinical Practice: A Retrospective Investigation of Causative Factors.
Topics: Adrenal Insufficiency; Female; Fentanyl; Gestational Age; Humans; Hydrocortisone; Hyponatremia; Hypo | 2015 |
Secondary adrenal insufficiency due to opiate therapy - another differential diagnosis worth consideration.
Topics: Adrenal Cortex Hormones; Adrenal Insufficiency; Analgesics, Opioid; Diagnosis, Differential; Fentany | 2009 |
Postoperative adrenal crisis in a patient with Schmidt syndrome (autoimmune polyglandular endocrinopathy type II).
Topics: Adrenal Insufficiency; Adult; Anesthetics, Intravenous; Anti-Inflammatory Agents; Antithyroid Agents | 2004 |
Chronic fentanyl application induces adrenocortical insufficiency.
Topics: Administration, Cutaneous; Adrenal Insufficiency; Anti-Inflammatory Agents; Drug Administration Sche | 2005 |
Etomidate infusion and adrenocortical function. A study in elective surgery.
Topics: Adrenal Cortex; Adrenal Insufficiency; Anesthetics; Cosyntropin; Drug Tolerance; Etomidate; Female; | 1985 |