fentanyl has been researched along with Acute Post-Traumatic Stress Disorder in 9 studies
Fentanyl: A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078)
fentanyl : A monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of N-phenyl-1-(2-phenylethyl)piperidin-4-amine with propanoic acid.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Fentanyl was found at a high rate, even in the absence of other opioids, which suggests that some veterans might be consuming fentanyl with cocaine." | 1.62 | Brief Report: Rates of Fentanyl Use Among Psychiatric Emergency Room Patients. ( Campbell, S; Elmarasi, M; Fuehrlein, B; Garcia-Vassallo, G, 2021) |
| "Relative to healthy controls, both trauma-exposed groups had lower micro-opioid receptor BP2 in extended amygdala, nucleus accumbens, and dorsal frontal and insular cortex but had higher BP2 in the orbitofrontal cortex." | 1.34 | Altered central micro-opioid receptor binding after psychological trauma. ( Britton, JC; Bueller, JA; Fig, LM; Koeppe, RA; Liberzon, I; Phan, KL; Taylor, SF; Zubieta, JK, 2007) |
| "Ohmefentanyl (OMF) is a new mu opioid receptor agonist with high affinity and selectivity, and possesses anesthetic activity." | 1.30 | [Effects of ohmefentanyl at anesthetic dose on plasma levels of corticosterone, cortisol and antidiuretic hormone in rats]. ( Chi, ZQ; Jin, WQ; Jin, XL; Li, GF; Zhou, DH, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 4 (44.44) | 24.3611 |
| 2020's | 2 (22.22) | 2.80 |
| Authors | Studies |
|---|---|
| Bardo, MT | 1 |
| Chandler, CM | 1 |
| Denehy, ED | 1 |
| Carper, BA | 1 |
| Prendergast, MA | 1 |
| Nolen, TL | 1 |
| Elmarasi, M | 1 |
| Garcia-Vassallo, G | 1 |
| Campbell, S | 1 |
| Fuehrlein, B | 1 |
| Melcer, T | 2 |
| Walker, J | 2 |
| Sechriest, VF | 1 |
| Lebedda, M | 2 |
| Quinn, K | 2 |
| Galarneau, M | 2 |
| Bhatnagar, V | 1 |
| Richard, E | 1 |
| Han, P | 1 |
| Sechriest, V | 1 |
| Wallace, S | 1 |
| Mecklenburg, B | 1 |
| Hanling, S | 1 |
| Schofield, J | 1 |
| Johnston, AM | 1 |
| de Mello, WF | 1 |
| Roffey, P | 1 |
| Thangathurai, D | 1 |
| Liberzon, I | 1 |
| Taylor, SF | 1 |
| Phan, KL | 1 |
| Britton, JC | 1 |
| Fig, LM | 1 |
| Bueller, JA | 1 |
| Koeppe, RA | 1 |
| Zubieta, JK | 1 |
| Jin, XL | 1 |
| Jin, WQ | 1 |
| Zhou, DH | 1 |
| Li, GF | 1 |
| Chi, ZQ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Dexmedetomidine Compared to Midazolam for Symptom Control in Advanced Cancer Patients: A Pilot Randomized Controlled Trial (RCT)[NCT01687751] | Phase 2 | 0 participants (Actual) | Interventional | 2012-11-30 | Withdrawn (stopped due to Study design determined to be not likely feasible) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
9 other studies available for fentanyl and Acute Post-Traumatic Stress Disorder
| Article | Year |
|---|---|
Effect of the glucocorticoid receptor antagonist PT150 on acquisition and escalation of fentanyl self-administration following early-life stress.
Topics: Animals; Corticosterone; Female; Fentanyl; Male; Rats; Rats, Sprague-Dawley; Receptors, Glucocortico | 2023 |
Brief Report: Rates of Fentanyl Use Among Psychiatric Emergency Room Patients.
Topics: Adult; Alcoholism; Cocaine; Depressive Disorder; Drug Contamination; Drug Overdose; Emergency Servic | 2021 |
Glasgow Coma Scores, early opioids, and posttraumatic stress disorder among combat amputees.
Topics: Afghan Campaign 2001-; Amnesia; Amputees; Analgesics, Opioid; Comorbidity; Drug Therapy, Combination | 2014 |
Glasgow Coma Scale scores, early opioids, and 4-year psychological outcomes among combat amputees.
Topics: Adult; Afghan Campaign 2001-; Amputation, Surgical; Amputation, Traumatic; Amputees; Analgesics, Opi | 2014 |
Profound reduction in sedation and analgesic requirements using extended dexmedetomidine infusions in a patient with an open abdomen.
Topics: Abdominal Injuries; Analgesics, Non-Narcotic; Dexmedetomidine; Fentanyl; Humans; Infusions, Intraven | 2009 |
Morphine after combat injury and post-traumatic stress disorder.
Topics: Analgesia; Analgesics, Opioid; Benzodiazepines; Fentanyl; Humans; Iraq War, 2003-2011; Ketamine; Mid | 2010 |
Posttraumatic stress disorder in cancer ICUs.
Topics: Anesthetics, Dissociative; Drug Therapy, Combination; Fentanyl; Humans; Intensive Care Units; Ketami | 2010 |
Altered central micro-opioid receptor binding after psychological trauma.
Topics: Adaptation, Physiological; Adult; Amygdala; Analgesics, Opioid; Cerebral Cortex; Fentanyl; Functiona | 2007 |
[Effects of ohmefentanyl at anesthetic dose on plasma levels of corticosterone, cortisol and antidiuretic hormone in rats].
Topics: Analgesics; Animals; Corticosterone; Fentanyl; Male; Rats; Stress Disorders, Post-Traumatic; Vasopre | 1997 |