fentanyl has been researched along with Acute Pain in 48 studies
Fentanyl: A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078)
fentanyl : A monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of N-phenyl-1-(2-phenylethyl)piperidin-4-amine with propanoic acid.
Acute Pain: Intensely discomforting, distressful, or agonizing sensation associated with trauma or disease, with well-defined location, character, and timing.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We aim to establish whether non-invasive methods such as inhalation of methoxyflurane is non-inferior to intranasal fentanyl or non-inferior to the well-known IV morphine in the pre-hospital treatment of acute pain." | 9.69 | Comparison of three regimens with inhalational methoxyflurane versus intranasal fentanyl versus intravenous morphine in pre-hospital acute pain management: study protocol for a randomized controlled trial (PreMeFen). ( Fjose, LO; Hagemo, J; Heyerdahl, F; Rehn, M; Simensen, R; Thorsen, K, 2023) |
| " Due to the reduction of this symptom with Haloperidol, we decided to design a randomized clinical trial to compare the analgesic effect of Ketamine with Haloperidol and Fentanyl in reducing acute pain and its complications." | 9.51 | Sub dissociative dose of ketamine with haloperidol versus fentanyl on pain reduction in patients with acute pain in the emergency department; a randomized clinical trial. ( Baratloo, A; Moradi, MM; Payandemehr, P; Safaie, A, 2022) |
| "The first objective of this systematic review was to investigate the effectiveness of ketamine compared to opioid analgesics for pain management in children aged two months to 18 years who have acute pain in the emergency department." | 9.22 | The Effectiveness of Ketamine Compared to Opioid Analgesics for management of acute pain in Children in The Emergency Department: systematic Review. ( Alanazi, E, 2022) |
| "We found that combining a single dose of IV parecoxib 40 mg with PCA fentanyl is an easy and effective method of acute pain control after major liver resection." | 9.22 | Effects of Pre-Existing Liver Disease on Acute Pain Management Using Patient-Controlled Analgesia Fentanyl With Parecoxib After Major Liver Resection: A Retrospective, Pragmatic Study. ( Chen, CL; Cheng, KW; Chiu, YC; Huang, CE; Huang, CJ; Jawan, B; Juang, SE; Lee, YE; Lim, KI; Shih, TH; Wang, CH; Wu, SC; Yang, SC, 2016) |
| "To assess the efficacy and safety of intranasal analgesic-dose ketamine as compared to intranasal fentanyl for pediatric acute pain." | 9.05 | Intranasal ketamine for acute pain management in children: A systematic review and meta-analysis. ( Anderson, JL; Bellolio, F; Homme, JL; Lee, JY; Oliveira J E Silva, L, 2020) |
| "The sufentanil 30 μg sublingual tablet (hereafter referred to as the sufentanil ST) is approved in the EU for acute moderate to severe pain in adults (Dzuveo™) and in the USA for acute pain severe enough to require an opioid analgesic and for which alternative treatments are inadequate (Dsuvia™)." | 9.01 | Sufentanil 30 µg Sublingual Tablet: A Review in Acute Pain. ( Deeks, ED, 2019) |
| "Our primary aim was to determine the analgesic efficacy and opioid-sparing effect of perioperative dexmedetomidine for acute pain after abdominal surgery in adults." | 8.93 | Perioperative dexmedetomidine for acute pain after abdominal surgery in adults. ( Jessen Lundorf, L; Korvenius Nedergaard, H; Møller, AM, 2016) |
| "Evidence suggests that nebulized fentanyl is as effective as IV opioids in the treatment of acute pain, with relatively few adverse effects." | 8.93 | Nebulized Fentanyl in Acute Pain: A Systematic Review. ( Thompson, DF; Thompson, JP, 2016) |
| "We identified and evaluated all randomized controlled trials (RCTs) and quasi-randomized trials to assess the effects of intranasal fentanyl (INF) versus alternative analgesic interventions in children with acute pain, with respect to reduction in pain score, occurrence of adverse events, patient tolerability, use of "rescue analgesia," patient/parental satisfaction and patient mortality." | 8.90 | Intranasal fentanyl for the management of acute pain in children. ( Barrett, MJ; Cronin, J; Grant, TS; Hom, J; Kandamany, N; McCoy, SC; Murphy, A; O'Sullivan, R; Wakai, A, 2014) |
| "The purpose of this article is to systematically review the use of fentanyl as an analgesic for breakthrough pain." | 8.87 | Fentanyl for breakthrough pain: a systematic review. ( Davis, MP, 2011) |
| "This study aimed to assess physician comfort, knowledge, and implementation barriers regarding the use of intranasal fentanyl (INF) for pain management in patients with long-bone fractures in a pediatric emergency department (ED) with an INF pain pathway." | 7.88 | Evaluating the Implementation Barriers of an Intranasal Fentanyl Pain Pathway for Pediatric Long-Bone Fractures. ( Arnautovic, T; Frazier, SB; Mullan, PC; Ramirez, DE; Sommese, K; Vazifedan, T, 2018) |
| "Remifentanil has been associated with increased acute and potentially chronic postoperative pain." | 6.87 | Randomized Controlled Trial on the Influence of Intraoperative Remifentanil versus Fentanyl on Acute and Chronic Pain after Cardiac Surgery. ( Ahlers, SJGM; Daeter, EJ; Dahan, A; de Hoogd, S; Knibbe, CAJ; Tibboel, D; van de Garde, EMW; van Dongen, EPA, 2018) |
| "Acute pain is one of the most common presenting complaints in pediatric patients presenting to the emergency department." | 6.58 | Analgesia for Children in Acute Pain in the Post-codeine Era. ( Poonai, N; Zhu, R, 2018) |
| "Hyperalgesia has been described following remifentanil and morphine use, but the question remains about the associated risk with acute fentanyl exposure." | 6.52 | Fentanyl-induced hyperalgesia in acute pain management. ( Kane-Gill, SL; Lyons, PJ; Nery, JP; Rivosecchi, RM, 2015) |
| "Ketamine is a well-known anesthetic with its use trailing back to the 1960s." | 6.52 | The use of subdissociative-dose ketamine for acute pain in the emergency department. ( Motov, SM; Sin, B; Ternas, T, 2015) |
| "If fentanyl does cause more hyperalgesia compared to other opioids, it does not seem to have a significant impact on opioid consumption after ED discharge." | 5.72 | Association between fentanyl treatment for acute pain in the emergency department and opioid use two weeks after discharge. ( Chauny, JM; Choinière, M; Cournoyer, A; Daoust, R; Emond, M; Gosselin, S; Huard, V; Lang, E; Lavigne, G; Paquet, J; Perry, JJ; Williamson, D; Yan, JW, 2022) |
| "Acute pain is the most common symptom in the emergency setting and its optimal management continues to challenge prehospital emergency care practitioners, particularly in the paediatric population." | 5.46 | Intranasal fentanyl for the prehospital management of acute pain in children. ( Crispino, G; Hughes, M; Mccoy, S; Murphy, AP; O'Sullivan, R; Wakai, A, 2017) |
| "Fentanyl ITS, in the management of acute postoperative pain, offered safety advantages in terms of ORADEs compared with morphine iv." | 5.43 | A comparison of opioid-related adverse events with fentanyl iontophoretic transdermal system versus morphine intravenous patient-controlled analgesia in acute postoperative pain. ( Danesi, H; Ding, L; Grond, S; Jones, JB; Sinatra, RS; Viscusi, ER, 2016) |
| "5 μg/kg intranasal fentanyl in children 4 to 17 years old with acute pain from suspected isolated extremity fractures presenting to an urban Level II pediatric trauma center from December 2015 to November 2016." | 5.24 | Randomized Controlled Feasibility Trial of Intranasal Ketamine Compared to Intranasal Fentanyl for Analgesia in Children with Suspected Extremity Fractures. ( Bryant, KK; Dunn, C; Hogg, M; Moore, CG; Reynolds, SL; Runyon, MS; Studnek, JR; Templin, MA; Walker, KR; Young, JR, 2017) |
| "We found that combining a single dose of IV parecoxib 40 mg with PCA fentanyl is an easy and effective method of acute pain control after major liver resection." | 5.22 | Effects of Pre-Existing Liver Disease on Acute Pain Management Using Patient-Controlled Analgesia Fentanyl With Parecoxib After Major Liver Resection: A Retrospective, Pragmatic Study. ( Chen, CL; Cheng, KW; Chiu, YC; Huang, CE; Huang, CJ; Jawan, B; Juang, SE; Lee, YE; Lim, KI; Shih, TH; Wang, CH; Wu, SC; Yang, SC, 2016) |
| "The first objective of this systematic review was to investigate the effectiveness of ketamine compared to opioid analgesics for pain management in children aged two months to 18 years who have acute pain in the emergency department." | 5.22 | The Effectiveness of Ketamine Compared to Opioid Analgesics for management of acute pain in Children in The Emergency Department: systematic Review. ( Alanazi, E, 2022) |
| "To assess the efficacy and safety of intranasal analgesic-dose ketamine as compared to intranasal fentanyl for pediatric acute pain." | 5.05 | Intranasal ketamine for acute pain management in children: A systematic review and meta-analysis. ( Anderson, JL; Bellolio, F; Homme, JL; Lee, JY; Oliveira J E Silva, L, 2020) |
| "The sufentanil 30 μg sublingual tablet (hereafter referred to as the sufentanil ST) is approved in the EU for acute moderate to severe pain in adults (Dzuveo™) and in the USA for acute pain severe enough to require an opioid analgesic and for which alternative treatments are inadequate (Dsuvia™)." | 5.01 | Sufentanil 30 µg Sublingual Tablet: A Review in Acute Pain. ( Deeks, ED, 2019) |
| "The primary objective of this review is to provide an updated, comprehensive overview on the efficacy of intranasal fentanyl (INF) for acute pain relief in the pediatric population." | 4.98 | Treatment of pain with intranasal fentanyl in pediatric patients in an acute care setting: a systematic review. ( Friedland, H; Setlur, A, 2018) |
| "Our primary aim was to determine the analgesic efficacy and opioid-sparing effect of perioperative dexmedetomidine for acute pain after abdominal surgery in adults." | 4.93 | Perioperative dexmedetomidine for acute pain after abdominal surgery in adults. ( Jessen Lundorf, L; Korvenius Nedergaard, H; Møller, AM, 2016) |
| "This review aims at describing the technology, pharmacology and clinical efficacy of fentanyl iontophoretic transdermal system (ITS) in the treatment of acute pain." | 4.93 | Iontophoretic transdermal fentanyl for the management of acute perioperative pain in hospitalized patients. ( Chelly, JE; Fanelli, A; Sorella, MC, 2016) |
| "We identified and evaluated all randomized controlled trials (RCTs) and quasi-randomized trials to assess the effects of intranasal fentanyl (INF) versus alternative analgesic interventions in children with acute pain, with respect to reduction in pain score, occurrence of adverse events, patient tolerability, use of "rescue analgesia," patient/parental satisfaction and patient mortality." | 4.90 | Intranasal fentanyl for the management of acute pain in children. ( Barrett, MJ; Cronin, J; Grant, TS; Hom, J; Kandamany, N; McCoy, SC; Murphy, A; O'Sullivan, R; Wakai, A, 2014) |
| "The purpose of this article is to systematically review the use of fentanyl as an analgesic for breakthrough pain." | 4.87 | Fentanyl for breakthrough pain: a systematic review. ( Davis, MP, 2011) |
| " Cases were categorized based on adherence to a dosing strategy and LDI indication, including OUD and acute pain, non-prescribed fentanyl exposure, and transition from methadone." | 4.12 | Development of an intravenous low-dose buprenorphine initiation protocol. ( Bodnar, AR; Jablonski, LA; Stewart, RW, 2022) |
| "This study aimed to assess physician comfort, knowledge, and implementation barriers regarding the use of intranasal fentanyl (INF) for pain management in patients with long-bone fractures in a pediatric emergency department (ED) with an INF pain pathway." | 3.88 | Evaluating the Implementation Barriers of an Intranasal Fentanyl Pain Pathway for Pediatric Long-Bone Fractures. ( Arnautovic, T; Frazier, SB; Mullan, PC; Ramirez, DE; Sommese, K; Vazifedan, T, 2018) |
| "In this prospective observational study, we administered intranasal fentanyl in the out-of-hospital setting to adults and children older than 8 years with severe pain resulting from orthopedic conditions, abdominal pain, or acute coronary syndrome refractory to nitroglycerin spray." | 3.80 | Safety of intranasal fentanyl in the out-of-hospital setting: a prospective observational study. ( Dahl, JB; Hansen, MS; Karlsen, AP; Pedersen, DM; Trautner, S, 2014) |
| "A protocol for administering intranasal fentanyl for children age 1-15 years with acute pain was introduced to the ED Nursing staff by an educational session conducted by a clinical pharmacist." | 3.79 | The impact of interprofessional collaboration on nurses' satisfaction and comfort with intranasal fentanyl. ( Kwan, F; Moadebi, S; Reddekopp, L; Stackhouse, S, 2013) |
| "Remifentanil has been associated with increased acute and potentially chronic postoperative pain." | 2.87 | Randomized Controlled Trial on the Influence of Intraoperative Remifentanil versus Fentanyl on Acute and Chronic Pain after Cardiac Surgery. ( Ahlers, SJGM; Daeter, EJ; Dahan, A; de Hoogd, S; Knibbe, CAJ; Tibboel, D; van de Garde, EMW; van Dongen, EPA, 2018) |
| " The main outcomes were (1) measurable pain reduction (effectiveness) and (2) no occurrence of any serious adverse events." | 2.72 | The effectiveness and safety of paediatric prehospital pain management: a systematic review. ( Abebe, Y; Hetmann, F; Holland, M; Staff, T; Sumera, K, 2021) |
| "Acute pain is one of the most common presenting complaints in pediatric patients presenting to the emergency department." | 2.58 | Analgesia for Children in Acute Pain in the Post-codeine Era. ( Poonai, N; Zhu, R, 2018) |
| "Ketamine is a well-known anesthetic with its use trailing back to the 1960s." | 2.52 | The use of subdissociative-dose ketamine for acute pain in the emergency department. ( Motov, SM; Sin, B; Ternas, T, 2015) |
| "Hyperalgesia has been described following remifentanil and morphine use, but the question remains about the associated risk with acute fentanyl exposure." | 2.52 | Fentanyl-induced hyperalgesia in acute pain management. ( Kane-Gill, SL; Lyons, PJ; Nery, JP; Rivosecchi, RM, 2015) |
| "BACKGROUND: Treatment of acute pain is an essential element of pre-hospital care for injured and critically ill patients." | 1.91 | Application of analgesics in emergency services in Germany: a survey of the medical directors. ( Scharonow, M; Scharonow, O; Vilcane, S; Weilbach, C, 2023) |
| "Acetaminophen was mixed with all 18 solutions and was examined at time 0, 15, 30, and 60 min." | 1.72 | Compatibility of intravenous acetaminophen with morphine, fentanyl and ketamine in acute pediatric pain setting. ( Chan, MTV; Cheaib, A; O'Loughlin, E; Peng, YG; Williams, R, 2022) |
| "If fentanyl does cause more hyperalgesia compared to other opioids, it does not seem to have a significant impact on opioid consumption after ED discharge." | 1.72 | Association between fentanyl treatment for acute pain in the emergency department and opioid use two weeks after discharge. ( Chauny, JM; Choinière, M; Cournoyer, A; Daoust, R; Emond, M; Gosselin, S; Huard, V; Lang, E; Lavigne, G; Paquet, J; Perry, JJ; Williamson, D; Yan, JW, 2022) |
| "Fentanyl was most frequently used for APT (n = 19)." | 1.51 | Intranasal Analgesia and Sedation in Pediatric Emergency Care-A Prospective Observational Study on the Implementation of an Institutional Protocol in a Tertiary Children's Hospital. ( Bantel, C; Eich, C; Fieler, M; Jacobsen, N; Nemeth, M; Sümpelmann, R, 2019) |
| "Acute pain is a frequent symptom, but little is known about the frequency and causes of acute pain in the prehospital population." | 1.48 | Acute pain in the prehospital setting: a register-based study of 41.241 patients. ( Christensen, EF; Friesgaard, KD; Kirkegaard, H; Nikolajsen, L; Riddervold, IS, 2018) |
| "Fentanyl ITS, in the management of acute postoperative pain, offered safety advantages in terms of ORADEs compared with morphine iv." | 1.43 | A comparison of opioid-related adverse events with fentanyl iontophoretic transdermal system versus morphine intravenous patient-controlled analgesia in acute postoperative pain. ( Danesi, H; Ding, L; Grond, S; Jones, JB; Sinatra, RS; Viscusi, ER, 2016) |
| "Carrageenan-induced hyperalgesia is a widely used pain model in rodents." | 1.40 | Differential effects of opioid-related ligands and NSAIDs in nonhuman primate models of acute and inflammatory pain. ( Ko, MC; Lee, H; Rice, KC; Sukhtankar, DD, 2014) |
| "Patient records of conscious adult trauma victims transported by our air rescue helicopter service over 10 yr were reviewed retrospectively." | 1.39 | Undertreatment of acute pain (oligoanalgesia) and medical practice variation in prehospital analgesia of adult trauma patients: a 10 yr retrospective study. ( Albrecht, E; Decosterd, I; Hugli, O; Schoettker, P; Taffe, P; Yersin, B, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 34 (70.83) | 24.3611 |
| 2020's | 14 (29.17) | 2.80 |
| Authors | Studies |
|---|---|
| Abebe, Y | 1 |
| Hetmann, F | 1 |
| Sumera, K | 1 |
| Holland, M | 1 |
| Staff, T | 1 |
| Daoust, R | 1 |
| Paquet, J | 1 |
| Huard, V | 1 |
| Chauny, JM | 1 |
| Lavigne, G | 1 |
| Williamson, D | 1 |
| Choinière, M | 1 |
| Lang, E | 1 |
| Yan, JW | 1 |
| Perry, JJ | 1 |
| Emond, M | 1 |
| Gosselin, S | 1 |
| Cournoyer, A | 1 |
| Lindbeck, G | 1 |
| Shah, MI | 1 |
| Braithwaite, S | 1 |
| Powell, JR | 1 |
| Panchal, AR | 1 |
| Browne, LR | 1 |
| Lang, ES | 1 |
| Burton, B | 1 |
| Coughenour, J | 1 |
| Crowe, RP | 1 |
| Degn, H | 1 |
| Hedges, M | 1 |
| Gasper, J | 1 |
| Guild, K | 1 |
| Mattera, C | 1 |
| Nasca, S | 1 |
| Taillac, P | 1 |
| Warth, M | 1 |
| Moradi, MM | 2 |
| Safaie, A | 1 |
| Baratloo, A | 1 |
| Payandemehr, P | 1 |
| O'Loughlin, E | 1 |
| Peng, YG | 1 |
| Cheaib, A | 1 |
| Chan, MTV | 1 |
| Williams, R | 1 |
| Jablonski, LA | 1 |
| Bodnar, AR | 1 |
| Stewart, RW | 1 |
| Alanazi, E | 1 |
| Berke, MS | 1 |
| Colding-Jørgensen, P | 1 |
| Pedersen, LG | 1 |
| Hestehave, S | 1 |
| Kalliokoski, O | 1 |
| Jensen, HE | 1 |
| Sørensen, DB | 1 |
| Hau, J | 1 |
| Abelson, KS | 1 |
| Oni, MO | 1 |
| Archer, NM | 1 |
| Simensen, R | 1 |
| Fjose, LO | 1 |
| Rehn, M | 1 |
| Hagemo, J | 1 |
| Thorsen, K | 1 |
| Heyerdahl, F | 1 |
| Vilcane, S | 1 |
| Scharonow, O | 1 |
| Weilbach, C | 1 |
| Scharonow, M | 1 |
| Shin, HJ | 1 |
| Do, SH | 1 |
| Lee, JS | 1 |
| Kim, TK | 1 |
| Na, HS | 1 |
| Macintyre, PE | 1 |
| Roberts, LJ | 1 |
| Huxtable, CA | 1 |
| Oliveira J E Silva, L | 1 |
| Lee, JY | 1 |
| Bellolio, F | 1 |
| Homme, JL | 1 |
| Anderson, JL | 1 |
| Myrick, R | 1 |
| Blakemore, S | 1 |
| Waite, E | 1 |
| Pernell, B | 1 |
| Madan-Swain, A | 1 |
| Hilliard, L | 1 |
| Lebensburger, J | 1 |
| Katz, P | 2 |
| Takyar, S | 2 |
| Palmer, P | 2 |
| Liedgens, H | 2 |
| de Hoogd, S | 1 |
| Ahlers, SJGM | 1 |
| van Dongen, EPA | 1 |
| van de Garde, EMW | 1 |
| Daeter, EJ | 1 |
| Dahan, A | 1 |
| Tibboel, D | 1 |
| Knibbe, CAJ | 1 |
| Poonai, N | 1 |
| Zhu, R | 1 |
| Reynolds, SL | 1 |
| Bryant, KK | 1 |
| Studnek, JR | 1 |
| Hogg, M | 1 |
| Dunn, C | 1 |
| Templin, MA | 1 |
| Moore, CG | 1 |
| Young, JR | 1 |
| Walker, KR | 1 |
| Runyon, MS | 1 |
| Arnautovic, T | 1 |
| Sommese, K | 1 |
| Mullan, PC | 1 |
| Frazier, SB | 1 |
| Vazifedan, T | 1 |
| Ramirez, DE | 1 |
| Friesgaard, KD | 1 |
| Riddervold, IS | 1 |
| Kirkegaard, H | 1 |
| Christensen, EF | 1 |
| Nikolajsen, L | 1 |
| Setlur, A | 1 |
| Friedland, H | 1 |
| Deeks, ED | 1 |
| Podolsky, AT | 1 |
| Sandweiss, A | 1 |
| Hu, J | 1 |
| Bilsky, EJ | 1 |
| Cain, JP | 1 |
| Kumirov, VK | 1 |
| Lee, YS | 1 |
| Hruby, VJ | 1 |
| Vardanyan, RS | 1 |
| Vanderah, TW | 1 |
| Sukhtankar, DD | 1 |
| Lee, H | 1 |
| Rice, KC | 1 |
| Ko, MC | 1 |
| Karlsen, AP | 1 |
| Pedersen, DM | 1 |
| Trautner, S | 2 |
| Dahl, JB | 2 |
| Hansen, MS | 2 |
| Farahmand, S | 1 |
| Shiralizadeh, S | 1 |
| Talebian, MT | 1 |
| Bagheri-Hariri, S | 1 |
| Arbab, M | 1 |
| Basirghafouri, H | 1 |
| Saeedi, M | 1 |
| Sedaghat, M | 1 |
| Mirzababai, H | 1 |
| Murphy, A | 1 |
| O'Sullivan, R | 2 |
| Wakai, A | 2 |
| Grant, TS | 1 |
| Barrett, MJ | 1 |
| Cronin, J | 1 |
| McCoy, SC | 1 |
| Hom, J | 1 |
| Kandamany, N | 1 |
| Sin, B | 1 |
| Ternas, T | 1 |
| Motov, SM | 1 |
| Lyons, PJ | 1 |
| Rivosecchi, RM | 1 |
| Nery, JP | 1 |
| Kane-Gill, SL | 1 |
| Viscusi, ER | 2 |
| Grond, S | 1 |
| Ding, L | 1 |
| Danesi, H | 1 |
| Jones, JB | 1 |
| Sinatra, RS | 1 |
| Fanelli, A | 1 |
| Sorella, MC | 1 |
| Chelly, JE | 1 |
| Jessen Lundorf, L | 1 |
| Korvenius Nedergaard, H | 1 |
| Møller, AM | 1 |
| Song, IK | 1 |
| Park, YH | 1 |
| Lee, JH | 1 |
| Kim, JT | 1 |
| Choi, IH | 1 |
| Kim, HS | 1 |
| Ruest, S | 1 |
| Anderson, A | 1 |
| Murphy, AP | 1 |
| Hughes, M | 1 |
| Mccoy, S | 1 |
| Crispino, G | 1 |
| Lim, KI | 1 |
| Chiu, YC | 1 |
| Chen, CL | 1 |
| Wang, CH | 1 |
| Huang, CJ | 1 |
| Cheng, KW | 1 |
| Wu, SC | 1 |
| Shih, TH | 1 |
| Yang, SC | 1 |
| Juang, SE | 1 |
| Huang, CE | 1 |
| Jawan, B | 1 |
| Lee, YE | 1 |
| Thompson, JP | 1 |
| Thompson, DF | 1 |
| Lemke, J | 1 |
| Sardariani, E | 1 |
| Phipps, JB | 1 |
| Patel, N | 1 |
| Itri, LM | 1 |
| Caravelli, J | 1 |
| Nemeth, M | 1 |
| Jacobsen, N | 1 |
| Bantel, C | 1 |
| Fieler, M | 1 |
| Sümpelmann, R | 1 |
| Eich, C | 1 |
| Spahn, V | 1 |
| Del Vecchio, G | 1 |
| Labuz, D | 1 |
| Rodriguez-Gaztelumendi, A | 1 |
| Massaly, N | 1 |
| Temp, J | 1 |
| Durmaz, V | 1 |
| Sabri, P | 1 |
| Reidelbach, M | 1 |
| Machelska, H | 1 |
| Weber, M | 1 |
| Stein, C | 1 |
| Davis, MP | 1 |
| Mathiesen, O | 1 |
| Paech, MJ | 1 |
| Bloor, M | 1 |
| Schug, SA | 1 |
| Engelman, E | 1 |
| Marsala, C | 1 |
| Albrecht, E | 1 |
| Taffe, P | 1 |
| Yersin, B | 1 |
| Schoettker, P | 1 |
| Decosterd, I | 1 |
| Hugli, O | 1 |
| Moadebi, S | 1 |
| Kwan, F | 1 |
| Stackhouse, S | 1 |
| Reddekopp, L | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomised Clinical Trial Evaluating the Effect of Remifentanil vs Fentanyl During Cardiac Surgery on the Incidence of Chronic Thoracic Pain[NCT02031016] | Phase 4 | 126 participants (Actual) | Interventional | 2014-02-28 | Completed | ||
| Intranasal Sufentanil for Analgesia of Severe Sickle Cell Vaso-occlusive Pain Crisis in the Pediatric Emergency Department: a Double Blind Randomized Versus Placebo Controlled Trial[NCT06181695] | Phase 3 | 182 participants (Anticipated) | Interventional | 2024-05-02 | Not yet recruiting | ||
| The Impact of Sublingual Sufentanil on Postoperative Pain and Analgesic[NCT04263909] | Phase 4 | 30 participants (Anticipated) | Interventional | 2020-12-01 | Active, not recruiting | ||
| Prehospital Analgesia With Intra-Nasal Ketamine[NCT02753114] | Phase 4 | 120 participants (Actual) | Interventional | 2017-11-06 | Completed | ||
| Comparison of Sub-dissociative Dose Intranasal Ketamine to Intranasal Fentanyl for Treatment of Moderate to Severe Pain in Pediatric Patients Presenting to the Emergency Department: a Prospective, Randomized, Double-blind Study[NCT02388321] | Phase 4 | 22 participants (Actual) | Interventional | 2015-05-01 | Terminated (stopped due to Patients meeting inclusion criteria was low, and PI went to another institution.) | ||
| A Combination Study With Sub-Dissociative Ketamine and Fentanyl to Treat Moderate to Severe Pain in the Emergency Department[NCT03959852] | Phase 4 | 6 participants (Actual) | Interventional | 2019-11-18 | Terminated (stopped due to Residency completed.) | ||
| Patient Satisfaction With Subdissociative Dose Ketamine Versus Morphine for Emergency Department Pain Control[NCT04698772] | 32 participants (Actual) | Observational | 2019-12-19 | Completed | |||
| ED Treatment of Suicidal Patients With Ketamine Infusion[NCT03502551] | Phase 2 | 0 participants (Actual) | Interventional | 2019-04-01 | Withdrawn (stopped due to Trial never received funding.) | ||
| Effect of Dexmedetomidine Combined With Dezocine and Flubiprofen for Postoperative Intravenous Patient Controlled Analgesia After Colorectal Surgery[NCT03014713] | Phase 4 | 50 participants (Anticipated) | Interventional | 2016-09-30 | Recruiting | ||
| A Prospective Study Comparing the Efficacy and Safety of 100 mcg and 200 mcg of Intranasal Fentanyl Pectin Spray as an Analgesic in Adult Males Undergoing Outpatient Cystoscopic Procedures[NCT01756651] | Phase 1 | 20 participants (Actual) | Interventional | 2013-02-28 | Completed | ||
| Dexmedetomidine Comme Adjuvant à la rachianesthésie Lors de césariennes électives : Une étude Pilote[NCT05099055] | Phase 3 | 42 participants (Actual) | Interventional | 2022-03-15 | Completed | ||
| Pain Management in Adults in Primary Intervention of the Mobile Emergency and Resuscitation Service of Pontoise[NCT05791253] | 365 participants (Actual) | Observational | 2023-03-09 | Completed | |||
| Determination of Analgesic Equipotent Doses of Inhaled Metoxyflurane vs. Intravenous Fentanyl Using Cold Pressor Test (CPT) in Volunteers: A Randomized, Double Blind, Placebo-controlled Crossover Study.[NCT03894800] | Phase 4 | 12 participants (Actual) | Interventional | 2019-04-23 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
The patient were asked at 30 minutes post administration of analgesia if they experienced any side effects like nausea, vomiting, headache etc. (NCT02388321)
Timeframe: 30 minutes
| Intervention | Participants (Count of Participants) |
|---|---|
| Ketamine | 0 |
| Fentanyl | 0 |
An 11 point Likert Visual Analog Scale with 0 being no pain, 5 being moderate pain and 10 being very severe pain was verbally administered to the patient at 30 minutes post administration of analgesia. (NCT02388321)
Timeframe: 30 minutes
| Intervention | units on a scale (Mean) |
|---|---|
| Ketamine | 3.36 |
| Fentanyl | 2.09 |
19 reviews available for fentanyl and Acute Pain
| Article | Year |
|---|---|
The effectiveness and safety of paediatric prehospital pain management: a systematic review.
Topics: Acute Pain; Analgesics; Analgesics, Opioid; Child; Emergency Medical Services; Fentanyl; Humans | 2021 |
The Effectiveness of Ketamine Compared to Opioid Analgesics for management of acute pain in Children in The Emergency Department: systematic Review.
Topics: Acute Pain; Analgesics; Analgesics, Opioid; Child; Emergency Service, Hospital; Fentanyl; Humans; Ke | 2022 |
Management of Opioid-Tolerant Patients with Acute Pain: Approaching the Challenges.
Topics: Acute Pain; Analgesics; Analgesics, Opioid; Animals; Drug Tolerance; Fentanyl; Humans; Pain Measurem | 2020 |
Intranasal ketamine for acute pain management in children: A systematic review and meta-analysis.
Topics: Acute Pain; Administration, Intranasal; Analgesics; Child; Fentanyl; Humans; Ketamine; Pain Manageme | 2020 |
Sublingual, transdermal and intravenous patient-controlled analgesia for acute post-operative pain: systematic literature review and mixed treatment comparison.
Topics: Acute Pain; Administration, Cutaneous; Administration, Sublingual; Analgesia, Patient-Controlled; An | 2017 |
Analgesia for Children in Acute Pain in the Post-codeine Era.
Topics: Acute Pain; Analgesics, Opioid; Child; Codeine; Emergency Service, Hospital; Fentanyl; Humans; Morph | 2018 |
Treatment of pain with intranasal fentanyl in pediatric patients in an acute care setting: a systematic review.
Topics: Acute Pain; Administration, Intranasal; Analgesics, Opioid; Child; Fentanyl; Humans | 2018 |
Sufentanil 30 µg Sublingual Tablet: A Review in Acute Pain.
Topics: Acute Pain; Administration, Intravenous; Administration, Sublingual; Analgesia, Patient-Controlled; | 2019 |
Intranasal fentanyl for the management of acute pain in children.
Topics: Acute Pain; Administration, Intranasal; Analgesics, Opioid; Child; Fentanyl; Humans; Morphine; Pain | 2014 |
The use of subdissociative-dose ketamine for acute pain in the emergency department.
Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Child; Emergency Service, Hospital; Female; Fenta | 2015 |
The use of subdissociative-dose ketamine for acute pain in the emergency department.
Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Child; Emergency Service, Hospital; Female; Fenta | 2015 |
The use of subdissociative-dose ketamine for acute pain in the emergency department.
Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Child; Emergency Service, Hospital; Female; Fenta | 2015 |
The use of subdissociative-dose ketamine for acute pain in the emergency department.
Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Child; Emergency Service, Hospital; Female; Fenta | 2015 |
The use of subdissociative-dose ketamine for acute pain in the emergency department.
Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Child; Emergency Service, Hospital; Female; Fenta | 2015 |
The use of subdissociative-dose ketamine for acute pain in the emergency department.
Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Child; Emergency Service, Hospital; Female; Fenta | 2015 |
The use of subdissociative-dose ketamine for acute pain in the emergency department.
Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Child; Emergency Service, Hospital; Female; Fenta | 2015 |
The use of subdissociative-dose ketamine for acute pain in the emergency department.
Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Child; Emergency Service, Hospital; Female; Fenta | 2015 |
The use of subdissociative-dose ketamine for acute pain in the emergency department.
Topics: Acute Pain; Adult; Analgesics; Analgesics, Opioid; Child; Emergency Service, Hospital; Female; Fenta | 2015 |
Fentanyl-induced hyperalgesia in acute pain management.
Topics: Acute Pain; Analgesics, Opioid; Fentanyl; Humans; Hyperalgesia; Pain Management | 2015 |
Iontophoretic transdermal fentanyl for the management of acute perioperative pain in hospitalized patients.
Topics: Acute Pain; Administration, Cutaneous; Analgesia, Patient-Controlled; Analgesics, Opioid; Clinical T | 2016 |
Perioperative dexmedetomidine for acute pain after abdominal surgery in adults.
Topics: Abdomen; Acute Pain; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Dexmedetomidine; Fentanyl; | 2016 |
Management of acute pediatric pain in the emergency department.
Topics: Acute Pain; Administration, Intranasal; Analgesics; Breast Feeding; Child; Conscious Sedation; Emerg | 2016 |
Nebulized Fentanyl in Acute Pain: A Systematic Review.
Topics: Acute Pain; Administration, Inhalation; Analgesics, Opioid; Child; Clinical Trials as Topic; Fentany | 2016 |
Fentanyl for breakthrough pain: a systematic review.
Topics: Acute Pain; Administration, Buccal; Administration, Intranasal; Administration, Mucosal; Administrat | 2011 |
Intranasal fentanyl in the treatment of acute pain--a systematic review.
Topics: Acute Pain; Administration, Intranasal; Analgesics, Opioid; Breakthrough Pain; Fentanyl; Humans; Pai | 2012 |
New formulations of fentanyl for acute pain management.
Topics: Acute Pain; Administration, Cutaneous; Administration, Intranasal; Administration, Oral; Analgesics, | 2012 |
Efficacy of adding clonidine to intrathecal morphine in acute postoperative pain: meta-analysis.
Topics: Acute Pain; Adrenergic alpha-Agonists; Analgesics, Opioid; Clonidine; Endpoint Determination; Fentan | 2013 |
8 trials available for fentanyl and Acute Pain
| Article | Year |
|---|---|
Sub dissociative dose of ketamine with haloperidol versus fentanyl on pain reduction in patients with acute pain in the emergency department; a randomized clinical trial.
Topics: Acute Pain; Adult; Analgesics; Double-Blind Method; Emergency Service, Hospital; Fentanyl; Haloperid | 2022 |
Comparison of three regimens with inhalational methoxyflurane versus intranasal fentanyl versus intravenous morphine in pre-hospital acute pain management: study protocol for a randomized controlled trial (PreMeFen).
Topics: Acute Pain; Fentanyl; Hospitals; Humans; Methoxyflurane; Morphine; Randomized Controlled Trials as T | 2023 |
Comparison of Intraoperative Sedation With Dexmedetomidine Versus Propofol on Acute Postoperative Pain in Total Knee Arthroplasty Under Spinal Anesthesia: A Randomized Trial.
Topics: Acute Pain; Adrenergic alpha-2 Receptor Agonists; Adult; Aged; Aged, 80 and over; Analgesia, Patient | 2019 |
Randomized Controlled Trial on the Influence of Intraoperative Remifentanil versus Fentanyl on Acute and Chronic Pain after Cardiac Surgery.
Topics: Acute Pain; Adult; Aged; Analgesics, Opioid; Cardiac Surgical Procedures; Chronic Pain; Female; Fent | 2018 |
Randomized Controlled Feasibility Trial of Intranasal Ketamine Compared to Intranasal Fentanyl for Analgesia in Children with Suspected Extremity Fractures.
Topics: Acute Pain; Administration, Intranasal; Adolescent; Analgesics; Arm Injuries; Child; Child, Preschoo | 2017 |
Nebulized fentanyl vs intravenous morphine for ED patients with acute limb pain: a randomized clinical trial.
Topics: Acute Pain; Administration, Inhalation; Adult; Analgesics, Opioid; Arm Injuries; Double-Blind Method | 2014 |
Randomized controlled trial on preemptive analgesia for acute postoperative pain management in children.
Topics: Acute Pain; Administration, Intravenous; Analgesia; Analgesia, Patient-Controlled; Analgesics, Opioi | 2016 |
Effects of Pre-Existing Liver Disease on Acute Pain Management Using Patient-Controlled Analgesia Fentanyl With Parecoxib After Major Liver Resection: A Retrospective, Pragmatic Study.
Topics: Acute Pain; Adult; Aged; Analgesia, Patient-Controlled; Analgesics; Drug Therapy, Combination; Femal | 2016 |
21 other studies available for fentanyl and Acute Pain
| Article | Year |
|---|---|
Association between fentanyl treatment for acute pain in the emergency department and opioid use two weeks after discharge.
Topics: Acute Pain; Adult; Aged; Analgesics, Opioid; Case-Control Studies; Emergency Service, Hospital; Fema | 2022 |
Evidence-Based Guidelines for Prehospital Pain Management: Recommendations.
Topics: Acetaminophen; Acute Pain; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; | 2023 |
Compatibility of intravenous acetaminophen with morphine, fentanyl and ketamine in acute pediatric pain setting.
Topics: Acetaminophen; Acute Pain; Analgesics, Opioid; Child; Double-Blind Method; Fentanyl; Humans; Ketamin | 2022 |
Development of an intravenous low-dose buprenorphine initiation protocol.
Topics: Acute Pain; Analgesics, Opioid; Buprenorphine; Fentanyl; Humans; Methadone; Opiate Substitution Trea | 2022 |
Effects of Transdermal Fentanyl Treatment on Acute Pain and Inflammation in Rats with Adjuvant-induced Monoarthritis.
Topics: Acute Pain; Adjuvants, Immunologic; Analgesics, Opioid; Animals; Female; Fentanyl; Freund's Adjuvant | 2022 |
Intranasal fentanyl works-Why are we not using it more to treat acute pain in sickle cell disease?
Topics: Acute Pain; Administration, Intranasal; Analgesics, Opioid; Anemia, Sickle Cell; Fentanyl; Humans | 2023 |
Application of analgesics in emergency services in Germany: a survey of the medical directors.
Topics: Acetaminophen; Acute Pain; Adult; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Butylsco | 2023 |
Outpatient pain clinic and intranasal fentanyl to improve sickle cell disease outcomes.
Topics: Acute Pain; Administration, Intranasal; Adolescent; Analgesics, Opioid; Anemia, Sickle Cell; Child; | 2020 |
Evaluating the Implementation Barriers of an Intranasal Fentanyl Pain Pathway for Pediatric Long-Bone Fractures.
Topics: Acute Pain; Administration, Intranasal; Adolescent; Analgesics, Opioid; Child; Child, Preschool; Eme | 2018 |
Acute pain in the prehospital setting: a register-based study of 41.241 patients.
Topics: Acute Pain; Adult; Ambulances; Analgesics, Opioid; Denmark; Female; Fentanyl; Hospitalization; Human | 2018 |
Novel fentanyl-based dual μ/δ-opioid agonists for the treatment of acute and chronic pain.
Topics: Acute Pain; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Chronic Pain; Dise | 2013 |
Differential effects of opioid-related ligands and NSAIDs in nonhuman primate models of acute and inflammatory pain.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Acute Pain | 2014 |
Safety of intranasal fentanyl in the out-of-hospital setting: a prospective observational study.
Topics: Abdominal Pain; Acute Coronary Syndrome; Acute Pain; Administration, Intranasal; Adolescent; Adult; | 2014 |
Safety of intranasal fentanyl in the out-of-hospital setting: a prospective observational study.
Topics: Abdominal Pain; Acute Coronary Syndrome; Acute Pain; Administration, Intranasal; Adolescent; Adult; | 2014 |
Safety of intranasal fentanyl in the out-of-hospital setting: a prospective observational study.
Topics: Abdominal Pain; Acute Coronary Syndrome; Acute Pain; Administration, Intranasal; Adolescent; Adult; | 2014 |
Safety of intranasal fentanyl in the out-of-hospital setting: a prospective observational study.
Topics: Abdominal Pain; Acute Coronary Syndrome; Acute Pain; Administration, Intranasal; Adolescent; Adult; | 2014 |
A comparison of opioid-related adverse events with fentanyl iontophoretic transdermal system versus morphine intravenous patient-controlled analgesia in acute postoperative pain.
Topics: Acetamides; Acute Pain; Administration, Cutaneous; Administration, Intravenous; Analgesia, Patient-C | 2016 |
Intranasal fentanyl for the prehospital management of acute pain in children.
Topics: Acute Pain; Administration, Intranasal; Age Factors; Analgesics, Opioid; Child; Child, Preschool; Co | 2017 |
Fentanyl Iontophoretic Transdermal System (IONSYS(®)) can be Safely used in the Hospital Environment with X-Rays, Computerized Tomography and Radiofrequency Identification Devices.
Topics: Acute Pain; Administration, Cutaneous; Analgesia, Patient-Controlled; Analgesics, Opioid; Drug Deliv | 2016 |
Intranasal Analgesia and Sedation in Pediatric Emergency Care-A Prospective Observational Study on the Implementation of an Institutional Protocol in a Tertiary Children's Hospital.
Topics: Acute Pain; Administration, Intranasal; Adolescent; Analgesia; Child; Child, Preschool; Conscious Se | 2019 |
A nontoxic pain killer designed by modeling of pathological receptor conformations.
Topics: Acute Pain; Adenosine Monophosphate; Analgesia; Analgesics, Opioid; Animals; Computer Simulation; Co | 2017 |
Indirect treatment comparison of two non-invasive patient-controlled analgesia treatments for acute post-operative pain management.
Topics: Acute Pain; Adult; Analgesia, Patient-Controlled; Analgesics, Opioid; Fentanyl; Humans; Iontophoresi | 2017 |
Undertreatment of acute pain (oligoanalgesia) and medical practice variation in prehospital analgesia of adult trauma patients: a 10 yr retrospective study.
Topics: Acute Pain; Adolescent; Adult; Aged; Aged, 80 and over; Aircraft; Analgesia; Analgesics, Opioid; Eme | 2013 |
Undertreatment of acute pain (oligoanalgesia) and medical practice variation in prehospital analgesia of adult trauma patients: a 10 yr retrospective study.
Topics: Acute Pain; Adolescent; Adult; Aged; Aged, 80 and over; Aircraft; Analgesia; Analgesics, Opioid; Eme | 2013 |
Undertreatment of acute pain (oligoanalgesia) and medical practice variation in prehospital analgesia of adult trauma patients: a 10 yr retrospective study.
Topics: Acute Pain; Adolescent; Adult; Aged; Aged, 80 and over; Aircraft; Analgesia; Analgesics, Opioid; Eme | 2013 |
Undertreatment of acute pain (oligoanalgesia) and medical practice variation in prehospital analgesia of adult trauma patients: a 10 yr retrospective study.
Topics: Acute Pain; Adolescent; Adult; Aged; Aged, 80 and over; Aircraft; Analgesia; Analgesics, Opioid; Eme | 2013 |
The impact of interprofessional collaboration on nurses' satisfaction and comfort with intranasal fentanyl.
Topics: Acute Pain; Administration, Intranasal; Analgesics, Opioid; Emergency Nursing; Fentanyl; Humans; Ins | 2013 |