fentanyl has been researched along with Acute Coronary Syndrome in 4 studies
Fentanyl: A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078)
fentanyl : A monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of N-phenyl-1-(2-phenylethyl)piperidin-4-amine with propanoic acid.
Acute Coronary Syndrome: An episode of MYOCARDIAL ISCHEMIA that generally lasts longer than a transient anginal episode that ultimately may lead to MYOCARDIAL INFARCTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Dual antiplatelet therapy (DAPT) remains the cornerstone of acute coronary syndrome (ACS) management, and ticagrelor is one of the commonly used second antiplatelet agents." | 9.41 | Comparison of the effect of Morphine and Fentanyl in patients with acute coronary syndrome receiving Ticagrelor - The COMET (Comparison Morphine, Fentayl and Ticagrelor) randomized controlled trial. ( Baber, U; Badimela, P; Balasubramaniyan, JV; Iyer, M; Jebaraj, R; Karthikeyan, G; Krishnamoorthy, P; Krishnamurthy, P; Malepati, B; Manokar, P; Muralidharan, TR; Murthy, JS; Paneerselvam, T; Ramadoss, M; Ramesh, S; Sadhanandham, S; Senguttuvan, NB; Suman, F; Thanikachalam, S; Vallivedu, MV; Vinod Kumar, B, 2021) |
| "In this prospective observational study, we administered intranasal fentanyl in the out-of-hospital setting to adults and children older than 8 years with severe pain resulting from orthopedic conditions, abdominal pain, or acute coronary syndrome refractory to nitroglycerin spray." | 3.80 | Safety of intranasal fentanyl in the out-of-hospital setting: a prospective observational study. ( Dahl, JB; Hansen, MS; Karlsen, AP; Pedersen, DM; Trautner, S, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 2 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Senguttuvan, NB | 1 |
| Suman, F | 1 |
| Paneerselvam, T | 1 |
| Malepati, B | 1 |
| Ramesh, S | 1 |
| Vallivedu, MV | 1 |
| Badimela, P | 1 |
| Ramadoss, M | 1 |
| Iyer, M | 1 |
| Krishnamurthy, P | 1 |
| Vinod Kumar, B | 1 |
| Balasubramaniyan, JV | 1 |
| Sadhanandham, S | 1 |
| Jebaraj, R | 1 |
| Manokar, P | 1 |
| Muralidharan, TR | 1 |
| Murthy, JS | 1 |
| Thanikachalam, S | 1 |
| Krishnamoorthy, P | 1 |
| Baber, U | 1 |
| Karthikeyan, G | 1 |
| Buckley, JP | 1 |
| Mylotte, D | 1 |
| McEvoy, JW | 1 |
| Karlsen, AP | 1 |
| Pedersen, DM | 1 |
| Trautner, S | 1 |
| Dahl, JB | 1 |
| Hansen, MS | 1 |
| Kucuk, HO | 1 |
| Kucuk, U | 1 |
| Kolcu, Z | 1 |
| Balta, S | 1 |
| Demirkol, S | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Prehospital Analgesia With Intra-Nasal Ketamine[NCT02753114] | Phase 4 | 120 participants (Actual) | Interventional | 2017-11-06 | Completed | ||
| Comparison of Sub-dissociative Dose Intranasal Ketamine to Intranasal Fentanyl for Treatment of Moderate to Severe Pain in Pediatric Patients Presenting to the Emergency Department: a Prospective, Randomized, Double-blind Study[NCT02388321] | Phase 4 | 22 participants (Actual) | Interventional | 2015-05-01 | Terminated (stopped due to Patients meeting inclusion criteria was low, and PI went to another institution.) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
The patient were asked at 30 minutes post administration of analgesia if they experienced any side effects like nausea, vomiting, headache etc. (NCT02388321)
Timeframe: 30 minutes
| Intervention | Participants (Count of Participants) |
|---|---|
| Ketamine | 0 |
| Fentanyl | 0 |
An 11 point Likert Visual Analog Scale with 0 being no pain, 5 being moderate pain and 10 being very severe pain was verbally administered to the patient at 30 minutes post administration of analgesia. (NCT02388321)
Timeframe: 30 minutes
| Intervention | units on a scale (Mean) |
|---|---|
| Ketamine | 3.36 |
| Fentanyl | 2.09 |
1 trial available for fentanyl and Acute Coronary Syndrome
| Article | Year |
|---|---|
Comparison of the effect of Morphine and Fentanyl in patients with acute coronary syndrome receiving Ticagrelor - The COMET (Comparison Morphine, Fentayl and Ticagrelor) randomized controlled trial.
Topics: Acute Coronary Syndrome; Fentanyl; Humans; Morphine; Percutaneous Coronary Intervention; Platelet Ag | 2021 |
3 other studies available for fentanyl and Acute Coronary Syndrome
| Article | Year |
|---|---|
Platelets and poppies: Do morphine and fentanyl differ?
Topics: Acute Coronary Syndrome; Analgesics, Opioid; Blood Platelets; Fentanyl; Humans; Morphine; Papaver; T | 2021 |
Safety of intranasal fentanyl in the out-of-hospital setting: a prospective observational study.
Topics: Abdominal Pain; Acute Coronary Syndrome; Acute Pain; Administration, Intranasal; Adolescent; Adult; | 2014 |
Safety of intranasal fentanyl in the out-of-hospital setting: a prospective observational study.
Topics: Abdominal Pain; Acute Coronary Syndrome; Acute Pain; Administration, Intranasal; Adolescent; Adult; | 2014 |
Safety of intranasal fentanyl in the out-of-hospital setting: a prospective observational study.
Topics: Abdominal Pain; Acute Coronary Syndrome; Acute Pain; Administration, Intranasal; Adolescent; Adult; | 2014 |
Safety of intranasal fentanyl in the out-of-hospital setting: a prospective observational study.
Topics: Abdominal Pain; Acute Coronary Syndrome; Acute Pain; Administration, Intranasal; Adolescent; Adult; | 2014 |
Misuse of fentanyl transdermal patch mixed with acute coronary syndrome.
Topics: Acute Coronary Syndrome; Adult; Analgesics, Opioid; Drug Overdose; Female; Fentanyl; Humans; Prescri | 2016 |