Page last updated: 2024-10-27

fentanyl and Acidosis

fentanyl has been researched along with Acidosis in 12 studies

Fentanyl: A potent narcotic analgesic, abuse of which leads to habituation or addiction. It is primarily a mu-opioid agonist. Fentanyl is also used as an adjunct to general anesthetics, and as an anesthetic for induction and maintenance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1078)
fentanyl : A monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of N-phenyl-1-(2-phenylethyl)piperidin-4-amine with propanoic acid.

Acidosis: A pathologic condition of acid accumulation or depletion of base in the body. The two main types are RESPIRATORY ACIDOSIS and metabolic acidosis, due to metabolic acid build up.

Research Excerpts

ExcerptRelevanceReference
"Patients receiving midazolam had a more than doubled risk of respiratory depression as mirrored by hypercapnia and acidosis, but not hypoxemia."7.88Midazolam addition to analgosedation for pulmonary vein isolation may increase risk of hypercapnia and acidosis. ( Bürkle, G; Ehrlich, JR; Feurich, F; Kaess, BM, 2018)
"Patients receiving midazolam had a more than doubled risk of respiratory depression as mirrored by hypercapnia and acidosis, but not hypoxemia."3.88Midazolam addition to analgosedation for pulmonary vein isolation may increase risk of hypercapnia and acidosis. ( Bürkle, G; Ehrlich, JR; Feurich, F; Kaess, BM, 2018)
"Neuroleptanalgesia was induced in late pregnancy in guinea pigs with diazepam and fentanyl-fluanisone."3.66Acid-base status of pregnant guinea pigs during neuroleptanalgesia with diazepam and fentanyl-fluanisone. ( Carter, AM, 1983)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19905 (41.67)18.7374
1990's3 (25.00)18.2507
2000's2 (16.67)29.6817
2010's2 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kaess, BM1
Feurich, F1
Bürkle, G1
Ehrlich, JR1
Agrafiotis, M1
Tryfon, S1
Siopi, D1
Chassapidou, G1
Galanou, A1
Tsara, V1
Awab, A1
Alilou, M1
El Moussaoui, R1
El Hijri, A1
Azzouzi, A1
Bedrick, AD1
Banner, W1
Balcom, RJ1
Bifano, EM1
Hakanson, DO1
Flecknell, PA1
John, M1
Mitchell, M1
Shurey, C1
Simpkin, S1
Carter, AM1
Stayer, SA1
Steven, JM1
Nicolson, SC1
Jobes, DR1
Stanley, C1
Baumgart, S1
Darvas, K1
Molnár, Z1
Irtó, I1
Tarjányi, M1
Flautner, L1
Raveau, A1
Noble, WH1
Baker, A1
Cavagna, R1
Vallini, A1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Prospective Study Comparing the Efficacy and Safety of 100 mcg and 200 mcg of Intranasal Fentanyl Pectin Spray as an Analgesic in Adult Males Undergoing Outpatient Cystoscopic Procedures[NCT01756651]Phase 120 participants (Actual)Interventional2013-02-28Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for fentanyl and Acidosis

ArticleYear
The metabolic effects of surface cooling neonates prior to cardiac surgery.
    Anesthesia and analgesia, 1994, Volume: 79, Issue:5

    Topics: Acidosis; Cardiac Surgical Procedures; Female; Fentanyl; Hemodynamics; Humans; Hypothermia, Induced;

1994

Other Studies

11 other studies available for fentanyl and Acidosis

ArticleYear
Midazolam addition to analgosedation for pulmonary vein isolation may increase risk of hypercapnia and acidosis.
    International journal of cardiology, 2018, 05-15, Volume: 259

    Topics: Acidosis; Aged; Anesthetics, Intravenous; Drug Therapy, Combination; Female; Fentanyl; Follow-Up Stu

2018
Successful management of drug-induced hypercapnic acidosis with naloxone and noninvasive positive pressure ventilation.
    The American journal of emergency medicine, 2015, Volume: 33, Issue:2

    Topics: Acidosis; Aged; Analgesics, Opioid; Combined Modality Therapy; Fentanyl; Humans; Hypercapnia; Male;

2015
[Rhabdomyolysis in severe acute asthma].
    Annales francaises d'anesthesie et de reanimation, 2009, Volume: 28, Issue:2

    Topics: Acidosis; Acute Disease; Adult; Albuterol; Anti-Asthmatic Agents; Asthma; Biomarkers; Combined Modal

2009
Pediatric emergency medicine: legal briefs.
    Pediatric emergency care, 2007, Volume: 23, Issue:3

    Topics: Acidosis; Administration, Cutaneous; Adult; Asphyxia; Brain Damage, Chronic; Burns, Chemical; Child;

2007
Alert: perioperative neonatal methemoglobinemia.
    American journal of diseases of children (1960), 1984, Volume: 138, Issue:9

    Topics: Acidosis; Anesthesia; Benzocaine; Female; Fentanyl; Humans; Infant, Newborn; Intraoperative Complica

1984
Neuroleptanalgesia in the rabbit.
    Laboratory animals, 1983, Volume: 17, Issue:2

    Topics: Acidosis; Animals; Butyrophenones; Diazepam; Drug Combinations; Etorphine; Fentanyl; Hypercapnia; Me

1983
Acid-base status of pregnant guinea pigs during neuroleptanalgesia with diazepam and fentanyl-fluanisone.
    Laboratory animals, 1983, Volume: 17, Issue:2

    Topics: Acid-Base Equilibrium; Acidosis; Animals; Blood Pressure; Butyrophenones; Diazepam; Drug Combination

1983
Anaesthesiological indications and contraindications of minimally invasive surgery.
    Acta chirurgica Hungarica, 1997, Volume: 36, Issue:1-4

    Topics: Acid-Base Equilibrium; Acidosis; Anesthesia, General; Anesthesia, Inhalation; Anesthesia, Intravenou

1997
Open heart surgery in infancy under deep hypothermia.
    Acta anaesthesiologica Belgica, 1977, Volume: 28, Issue:4

    Topics: Acidosis; Anesthesia, General; Arrhythmias, Cardiac; Dextrans; Evaluation Studies as Topic; Fentanyl

1977
MAO inhibitors and coronary artery surgery: a patient death.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1992, Volume: 39, Issue:10

    Topics: Acidosis; Anesthesia, Intravenous; Angina, Unstable; Cause of Death; Coronary Artery Bypass; Fentany

1992
[Changes in acid-base equilibrium induced by neuroleptoanalgesia].
    Minerva anestesiologica, 1968, Volume: 34, Issue:5

    Topics: Acid-Base Equilibrium; Acidosis; Adult; Aged; Benperidol; Epinephrine; Female; Fentanyl; Humans; Mal

1968