fenretinide and Lichen-Planus--Oral

fenretinide has been researched along with Lichen-Planus--Oral* in 1 studies

Trials

1 trial(s) available for fenretinide and Lichen-Planus--Oral

Article	Year
Successful topical treatment of oral lichen planus and leukoplakias with fenretinide (4-HPR). Cancer letters, 1994, Jan-30, Volume: 76, Issue:2-3 Eight patients with diffuse (non-operable) pre-cancerous lesions (oral lichen or leukoplakias) were treated with fenretinidec (4-HPR) applied topically twice daily. After one month of therapy two patients had complete remission and the other six had a greater than 75% response. 4-HPR was well tolerated, and no local or distant side effects were observed. Topical treatment may be combined with oral administration at lower doses to obtain therapeutic results with less toxicity than observed with oral administration alone. A study to further evaluate the efficacy of topical treatment is in progress at our institute. Topics: Administration, Oral; Fenretinide; Humans; Leukoplakia, Oral; Lichen Planus, Oral; Precancerous Conditions	1994

Article

Year

Successful topical treatment of oral lichen planus and leukoplakias with fenretinide (4-HPR).

Cancer letters, 1994, Jan-30, Volume: 76, Issue:2-3

Eight patients with diffuse (non-operable) pre-cancerous lesions (oral lichen or leukoplakias) were treated with fenretinidec (4-HPR) applied topically twice daily. After one month of therapy two patients had complete remission and the other six had a greater than 75% response. 4-HPR was well tolerated, and no local or distant side effects were observed. Topical treatment may be combined with oral administration at lower doses to obtain therapeutic results with less toxicity than observed with oral administration alone. A study to further evaluate the efficacy of topical treatment is in progress at our institute.

Topics: Administration, Oral; Fenretinide; Humans; Leukoplakia, Oral; Lichen Planus, Oral; Precancerous Conditions

1994