fenoldopam has been researched along with Ischemia in 8 studies
Fenoldopam: A dopamine D1 receptor agonist that is used as an antihypertensive agent. It lowers blood pressure through arteriolar vasodilation.
Ischemia: A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "1 microg/kg/min of fenoldopam, unilateral renal ischemia (1 hour, left renal artery cross-clamping) followed by 4 hours of reperfusion, and unilateral renal I/R with fenoldopam infusion." | 3.73 | Fenoldopam inhibits nuclear translocation of nuclear factor kappa B in a rat model of surgical ischemic acute renal failure. ( Aravindan, N; Natarajan, M; Shaw, AD, 2006) |
| "Vasoactive compounds are known to affect intrarenal hemodynamics and gene transcription, but specific effects of fenoldopam in the setting of acute renal ischemia are not known." | 3.73 | Fenoldopam improves corticomedullary oxygen delivery and attenuates angiogenesis gene expression in acute ischemic renal injury. ( Aravindan, N; Riedel, B; Samuels, J; Shaw, A, 2006) |
| "The effects of fenoldopam, a dopamine-1 (DA-1) receptor agonist, were studied in two groups of anesthetized dogs before and after induction of splanchnic ischemia by way of hemorrhage." | 3.71 | Dopamine-1 receptor stimulation attenuates the vasoconstrictive response to gut ischemia. ( Guzman, JA; Kruse, JA; Rosado, AE, 2001) |
| "The present studies were conducted to: a) comparatively evaluate the effects of clevidipine, a new dihydropyridine calcium antagonist, and fenoldopam, a dopamine (D-1) receptor agonist on basal renal function, and b) to determine the efficacy of these agents in protecting renal function in an experimental model of ischemia/reperfusion (I/R) induced acute renal failure in rats." | 3.71 | Effects of fenoldopam, a dopamine D-1 agonist, and clevidipine, a calcium channel antagonist, in acute renal failure in anesthetized rats. ( Jandhyala, BS; Stephens, CT, 2002) |
| " Of seven prospective studies using various dosing regimens of N-acetylcysteine, four revealed beneficial results." | 2.42 | Fenoldopam and N-acetylcysteine for the prevention of radiographic contrast material-induced nephropathy: a review. ( Brokering, KL; Theobald, JC; Walker, PD, 2003) |
| "Fenoldopam has no dopamine-2, alpha or beta-adrenergic activity and is 3." | 2.41 | [Fenoldopam: potential clinical applications in heart surgery]. ( Shorten, GD, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 8 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lepor, NE | 1 |
| Walker, PD | 1 |
| Brokering, KL | 1 |
| Theobald, JC | 1 |
| Napolitano, LM | 1 |
| Aravindan, N | 2 |
| Natarajan, M | 1 |
| Shaw, AD | 1 |
| Samuels, J | 1 |
| Riedel, B | 1 |
| Shaw, A | 1 |
| Guzman, JA | 1 |
| Rosado, AE | 1 |
| Kruse, JA | 1 |
| Shorten, GD | 1 |
| Stephens, CT | 1 |
| Jandhyala, BS | 1 |
3 reviews available for fenoldopam and Ischemia
| Article | Year |
|---|---|
A review of contemporary prevention strategies for radiocontrast nephropathy: a focus on fenoldopam and N-acetylcysteine.
Topics: Acetylcysteine; Animals; Contrast Media; Diabetes Complications; Dogs; Dopamine Agonists; Evaluation | 2003 |
Fenoldopam and N-acetylcysteine for the prevention of radiographic contrast material-induced nephropathy: a review.
Topics: Acetylcysteine; Contrast Media; Dopamine Agonists; Fenoldopam; Free Radical Scavengers; Humans; Isch | 2003 |
[Fenoldopam: potential clinical applications in heart surgery].
Topics: Acute Kidney Injury; Antihypertensive Agents; Coronary Artery Bypass; Diuretics; Dopamine Agonists; | 2001 |
5 other studies available for fenoldopam and Ischemia
| Article | Year |
|---|---|
Optimization of intestinal mucosal oxygenation in shock: a role for medical therapy?
Topics: Animals; Cell Respiration; Disease Models, Animal; Dogs; Dopamine; Fenoldopam; Intestinal Mucosa; Is | 2004 |
Fenoldopam inhibits nuclear translocation of nuclear factor kappa B in a rat model of surgical ischemic acute renal failure.
Topics: Acute Kidney Injury; Animals; Disease Models, Animal; DNA; Fenoldopam; Follow-Up Studies; Gene Expre | 2006 |
Fenoldopam improves corticomedullary oxygen delivery and attenuates angiogenesis gene expression in acute ischemic renal injury.
Topics: Acute Disease; Analysis of Variance; Angiogenesis Inducing Agents; Animals; Fenoldopam; Gene Express | 2006 |
Dopamine-1 receptor stimulation attenuates the vasoconstrictive response to gut ischemia.
Topics: Animals; Blood Pressure; Cardiac Output; Dogs; Dopamine Agonists; Fenoldopam; Heart Rate; Hemodynami | 2001 |
Effects of fenoldopam, a dopamine D-1 agonist, and clevidipine, a calcium channel antagonist, in acute renal failure in anesthetized rats.
Topics: Acute Kidney Injury; Animals; Disease Models, Animal; Dopamine Agonists; Fenoldopam; Glomerular Filt | 2002 |