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fenoldopam and Ischemia

fenoldopam has been researched along with Ischemia in 8 studies

Fenoldopam: A dopamine D1 receptor agonist that is used as an antihypertensive agent. It lowers blood pressure through arteriolar vasodilation.

Ischemia: A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.

Research Excerpts

ExcerptRelevanceReference
"1 microg/kg/min of fenoldopam, unilateral renal ischemia (1 hour, left renal artery cross-clamping) followed by 4 hours of reperfusion, and unilateral renal I/R with fenoldopam infusion."3.73Fenoldopam inhibits nuclear translocation of nuclear factor kappa B in a rat model of surgical ischemic acute renal failure. ( Aravindan, N; Natarajan, M; Shaw, AD, 2006)
"Vasoactive compounds are known to affect intrarenal hemodynamics and gene transcription, but specific effects of fenoldopam in the setting of acute renal ischemia are not known."3.73Fenoldopam improves corticomedullary oxygen delivery and attenuates angiogenesis gene expression in acute ischemic renal injury. ( Aravindan, N; Riedel, B; Samuels, J; Shaw, A, 2006)
"The effects of fenoldopam, a dopamine-1 (DA-1) receptor agonist, were studied in two groups of anesthetized dogs before and after induction of splanchnic ischemia by way of hemorrhage."3.71Dopamine-1 receptor stimulation attenuates the vasoconstrictive response to gut ischemia. ( Guzman, JA; Kruse, JA; Rosado, AE, 2001)
"The present studies were conducted to: a) comparatively evaluate the effects of clevidipine, a new dihydropyridine calcium antagonist, and fenoldopam, a dopamine (D-1) receptor agonist on basal renal function, and b) to determine the efficacy of these agents in protecting renal function in an experimental model of ischemia/reperfusion (I/R) induced acute renal failure in rats."3.71Effects of fenoldopam, a dopamine D-1 agonist, and clevidipine, a calcium channel antagonist, in acute renal failure in anesthetized rats. ( Jandhyala, BS; Stephens, CT, 2002)
" Of seven prospective studies using various dosing regimens of N-acetylcysteine, four revealed beneficial results."2.42Fenoldopam and N-acetylcysteine for the prevention of radiographic contrast material-induced nephropathy: a review. ( Brokering, KL; Theobald, JC; Walker, PD, 2003)
"Fenoldopam has no dopamine-2, alpha or beta-adrenergic activity and is 3."2.41[Fenoldopam: potential clinical applications in heart surgery]. ( Shorten, GD, 2001)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's8 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lepor, NE1
Walker, PD1
Brokering, KL1
Theobald, JC1
Napolitano, LM1
Aravindan, N2
Natarajan, M1
Shaw, AD1
Samuels, J1
Riedel, B1
Shaw, A1
Guzman, JA1
Rosado, AE1
Kruse, JA1
Shorten, GD1
Stephens, CT1
Jandhyala, BS1

Reviews

3 reviews available for fenoldopam and Ischemia

ArticleYear
A review of contemporary prevention strategies for radiocontrast nephropathy: a focus on fenoldopam and N-acetylcysteine.
    Reviews in cardiovascular medicine, 2003, Volume: 4 Suppl 1

    Topics: Acetylcysteine; Animals; Contrast Media; Diabetes Complications; Dogs; Dopamine Agonists; Evaluation

2003
Fenoldopam and N-acetylcysteine for the prevention of radiographic contrast material-induced nephropathy: a review.
    Pharmacotherapy, 2003, Volume: 23, Issue:12

    Topics: Acetylcysteine; Contrast Media; Dopamine Agonists; Fenoldopam; Free Radical Scavengers; Humans; Isch

2003
[Fenoldopam: potential clinical applications in heart surgery].
    Revista espanola de anestesiologia y reanimacion, 2001, Volume: 48, Issue:10

    Topics: Acute Kidney Injury; Antihypertensive Agents; Coronary Artery Bypass; Diuretics; Dopamine Agonists;

2001

Other Studies

5 other studies available for fenoldopam and Ischemia

ArticleYear
Optimization of intestinal mucosal oxygenation in shock: a role for medical therapy?
    Critical care medicine, 2004, Volume: 32, Issue:1

    Topics: Animals; Cell Respiration; Disease Models, Animal; Dogs; Dopamine; Fenoldopam; Intestinal Mucosa; Is

2004
Fenoldopam inhibits nuclear translocation of nuclear factor kappa B in a rat model of surgical ischemic acute renal failure.
    Journal of cardiothoracic and vascular anesthesia, 2006, Volume: 20, Issue:2

    Topics: Acute Kidney Injury; Animals; Disease Models, Animal; DNA; Fenoldopam; Follow-Up Studies; Gene Expre

2006
Fenoldopam improves corticomedullary oxygen delivery and attenuates angiogenesis gene expression in acute ischemic renal injury.
    Kidney & blood pressure research, 2006, Volume: 29, Issue:3

    Topics: Acute Disease; Analysis of Variance; Angiogenesis Inducing Agents; Animals; Fenoldopam; Gene Express

2006
Dopamine-1 receptor stimulation attenuates the vasoconstrictive response to gut ischemia.
    Journal of applied physiology (Bethesda, Md. : 1985), 2001, Volume: 91, Issue:2

    Topics: Animals; Blood Pressure; Cardiac Output; Dogs; Dopamine Agonists; Fenoldopam; Heart Rate; Hemodynami

2001
Effects of fenoldopam, a dopamine D-1 agonist, and clevidipine, a calcium channel antagonist, in acute renal failure in anesthetized rats.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2002, Volume: 24, Issue:4

    Topics: Acute Kidney Injury; Animals; Disease Models, Animal; Dopamine Agonists; Fenoldopam; Glomerular Filt

2002