fenoldopam has been researched along with Hypotension in 3 studies
Fenoldopam: A dopamine D1 receptor agonist that is used as an antihypertensive agent. It lowers blood pressure through arteriolar vasodilation.
Hypotension: Abnormally low BLOOD PRESSURE that can result in inadequate blood flow to the brain and other vital organs. Common symptom is DIZZINESS but greater negative impacts on the body occur when there is prolonged depravation of oxygen and nutrients.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Among patients with acute kidney injury after cardiac surgery, fenoldopam infusion, compared with placebo, did not reduce the need for renal replacement therapy or risk of 30-day mortality but was associated with an increased rate of hypotension." | 9.19 | Effect of fenoldopam on use of renal replacement therapy among patients with acute kidney injury after cardiac surgery: a randomized clinical trial. ( Alvaro, G; Amantea, B; Baldassarri, R; Bellomo, R; Bove, T; Calabrò, MG; Camata, A; Caramelli, F; Cariello, C; Comis, M; Conte, M; Dal Checco, E; Faita, L; Frontini, M; Galdieri, N; Guarracino, F; Landoni, G; Lembo, R; Maglioni, E; Martinez, B; Pala, G; Pappalardo, F; Pasero, DC; Paternoster, G; Persi, B; Pinelli, F; Pisano, A; Renzini, M; Saleh, O; Scandroglio, AM; Verdecchia, C; Zangrillo, A; Zucchetti, MC, 2014) |
| "Fenoldopam, a selective dopamine1 receptor agonist, has been recommended for induced hypotension because it effectively lowers arterial blood pressure and improves renal perfusion." | 7.68 | Cardiovascular function during induced hypotension by fenoldopam or sodium nitroprusside in anesthetized dogs. ( Jaffe, RS; Kien, ND; Moore, PG, 1992) |
| "Among patients with acute kidney injury after cardiac surgery, fenoldopam infusion, compared with placebo, did not reduce the need for renal replacement therapy or risk of 30-day mortality but was associated with an increased rate of hypotension." | 5.19 | Effect of fenoldopam on use of renal replacement therapy among patients with acute kidney injury after cardiac surgery: a randomized clinical trial. ( Alvaro, G; Amantea, B; Baldassarri, R; Bellomo, R; Bove, T; Calabrò, MG; Camata, A; Caramelli, F; Cariello, C; Comis, M; Conte, M; Dal Checco, E; Faita, L; Frontini, M; Galdieri, N; Guarracino, F; Landoni, G; Lembo, R; Maglioni, E; Martinez, B; Pala, G; Pappalardo, F; Pasero, DC; Paternoster, G; Persi, B; Pinelli, F; Pisano, A; Renzini, M; Saleh, O; Scandroglio, AM; Verdecchia, C; Zangrillo, A; Zucchetti, MC, 2014) |
| "Fenoldopam, a selective dopamine1 receptor agonist, has been recommended for induced hypotension because it effectively lowers arterial blood pressure and improves renal perfusion." | 3.68 | Cardiovascular function during induced hypotension by fenoldopam or sodium nitroprusside in anesthetized dogs. ( Jaffe, RS; Kien, ND; Moore, PG, 1992) |
| "Fenoldopam is a dopamine receptor alpha1-specific agonist that increases renal blood flow in patients with kidney failure." | 2.71 | Fenoldopam mesylate in early acute tubular necrosis: a randomized, double-blind, placebo-controlled clinical trial. ( Cotsonis, G; Finkel, KW; Murray, PT; Samuels, J; Shaw, AD; Tumlin, JA, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bove, T | 1 |
| Zangrillo, A | 1 |
| Guarracino, F | 1 |
| Alvaro, G | 1 |
| Persi, B | 1 |
| Maglioni, E | 1 |
| Galdieri, N | 1 |
| Comis, M | 1 |
| Caramelli, F | 1 |
| Pasero, DC | 1 |
| Pala, G | 1 |
| Renzini, M | 1 |
| Conte, M | 1 |
| Paternoster, G | 1 |
| Martinez, B | 1 |
| Pinelli, F | 1 |
| Frontini, M | 1 |
| Zucchetti, MC | 1 |
| Pappalardo, F | 1 |
| Amantea, B | 1 |
| Camata, A | 1 |
| Pisano, A | 1 |
| Verdecchia, C | 1 |
| Dal Checco, E | 1 |
| Cariello, C | 1 |
| Faita, L | 1 |
| Baldassarri, R | 1 |
| Scandroglio, AM | 1 |
| Saleh, O | 1 |
| Lembo, R | 1 |
| Calabrò, MG | 1 |
| Bellomo, R | 1 |
| Landoni, G | 1 |
| Tumlin, JA | 1 |
| Finkel, KW | 1 |
| Murray, PT | 1 |
| Samuels, J | 1 |
| Cotsonis, G | 1 |
| Shaw, AD | 1 |
| Kien, ND | 1 |
| Moore, PG | 1 |
| Jaffe, RS | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Efficacy of Fenoldopam in Reducing the Need for Renal Replacement Therapy After Cardiac Surgery. A Randomized Controlled Study.[NCT00621790] | Phase 3 | 667 participants (Actual) | Interventional | 2008-02-29 | Completed | ||
| Combination Fenoldopam Mesylate and Intravenous MESNA (2-mercaptoethane Sulphonate)in Early Acute Kidney Injury (AKD): A Randomized, Double-Blind Placebo Controlled Clinical Trial[NCT00286403] | Phase 2/Phase 3 | 0 participants (Actual) | Interventional | 2008-08-31 | Withdrawn (stopped due to The study was terminated due to logistics at a local hospital.) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for fenoldopam and Hypotension
| Article | Year |
|---|---|
Effect of fenoldopam on use of renal replacement therapy among patients with acute kidney injury after cardiac surgery: a randomized clinical trial.
Topics: Acute Kidney Injury; Aged; Cardiac Surgical Procedures; Creatinine; Critical Illness; Double-Blind M | 2014 |
Fenoldopam mesylate in early acute tubular necrosis: a randomized, double-blind, placebo-controlled clinical trial.
Topics: Creatinine; Diabetes Complications; Disease Progression; Dopamine Agonists; Double-Blind Method; Ear | 2005 |
1 other study available for fenoldopam and Hypotension
| Article | Year |
|---|---|
Cardiovascular function during induced hypotension by fenoldopam or sodium nitroprusside in anesthetized dogs.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Anesthesia, Inhalation; Animals; Dogs; F | 1992 |