Page last updated: 2024-10-27

fenoldopam and Critical Illness

fenoldopam has been researched along with Critical Illness in 11 studies

Fenoldopam: A dopamine D1 receptor agonist that is used as an antihypertensive agent. It lowers blood pressure through arteriolar vasodilation.

Critical Illness: A disease or state in which death is possible or imminent.

Research Excerpts

ExcerptRelevanceReference
"Among patients with acute kidney injury after cardiac surgery, fenoldopam infusion, compared with placebo, did not reduce the need for renal replacement therapy or risk of 30-day mortality but was associated with an increased rate of hypotension."9.19Effect of fenoldopam on use of renal replacement therapy among patients with acute kidney injury after cardiac surgery: a randomized clinical trial. ( Alvaro, G; Amantea, B; Baldassarri, R; Bellomo, R; Bove, T; Calabrò, MG; Camata, A; Caramelli, F; Cariello, C; Comis, M; Conte, M; Dal Checco, E; Faita, L; Frontini, M; Galdieri, N; Guarracino, F; Landoni, G; Lembo, R; Maglioni, E; Martinez, B; Pala, G; Pappalardo, F; Pasero, DC; Paternoster, G; Persi, B; Pinelli, F; Pisano, A; Renzini, M; Saleh, O; Scandroglio, AM; Verdecchia, C; Zangrillo, A; Zucchetti, MC, 2014)
"Among patients with acute kidney injury after cardiac surgery, fenoldopam infusion, compared with placebo, did not reduce the need for renal replacement therapy or risk of 30-day mortality but was associated with an increased rate of hypotension."5.19Effect of fenoldopam on use of renal replacement therapy among patients with acute kidney injury after cardiac surgery: a randomized clinical trial. ( Alvaro, G; Amantea, B; Baldassarri, R; Bellomo, R; Bove, T; Calabrò, MG; Camata, A; Caramelli, F; Cariello, C; Comis, M; Conte, M; Dal Checco, E; Faita, L; Frontini, M; Galdieri, N; Guarracino, F; Landoni, G; Lembo, R; Maglioni, E; Martinez, B; Pala, G; Pappalardo, F; Pasero, DC; Paternoster, G; Persi, B; Pinelli, F; Pisano, A; Renzini, M; Saleh, O; Scandroglio, AM; Verdecchia, C; Zangrillo, A; Zucchetti, MC, 2014)
" Two unblinded reviewers selected randomized controlled trials that used fenoldopam in the prevention or treatment of acute kidney injury in postoperative or intensive care patients."4.84Beneficial impact of fenoldopam in critically ill patients with or at risk for acute renal failure: a meta-analysis of randomized clinical trials. ( Biondi-Zoccai, GG; Bove, T; Calabrò, MG; De Luca, M; Landoni, G; Ranucci, M; Tumlin, JA; Zangrillo, A, 2007)
"Acute kidney injury is a frequent problem among many critically ill patients, commonly in the context of multiple organ failure and decreased renal perfusion."2.76Fenoldopam in critically ill patients with early renal dysfunction. A crossover study. ( Barquist, E; Cobas, M; Cudemus, G; De La Pena, M; Paparcuri, G; Varon, A, 2011)
"Fenoldopam mesylate is a selective dopamine-1 agonist, with no effect on dopamine-2 and alpha1 receptors, producing a selective renal vasodilation."2.72A comparison between fenoldopam and low-dose dopamine in early renal dysfunction of critically ill patients. ( Ancona, G; Bortone, D; Brienza, N; Bruno, F; Dalfino, L; Faconda, G; Fiore, T; Guagliardi, C; Malcangi, V; Ribezzi, M; Trerotoli, P, 2006)
"Fenoldopam was administered at different doses (0."2.71Monitoring renal oxygen supply in critically-ill patients using urinary oxygen tension. ( Alberto De Blasi, R; Coluzzi, F; Conti, G; Morelli, A; Orecchioni, A; Pietropaoli, P; Rocco, M, 2003)
"D."1.33Effect of fenoldopam mesylate in critically ill patients at risk for acute renal failure is dose dependent. ( Finkel, K; Gubert, M; Johnson, T; Samuels, J; Shaw, A, 2005)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (9.09)18.2507
2000's8 (72.73)29.6817
2010's2 (18.18)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bove, T2
Zangrillo, A2
Guarracino, F1
Alvaro, G1
Persi, B1
Maglioni, E1
Galdieri, N1
Comis, M1
Caramelli, F1
Pasero, DC1
Pala, G1
Renzini, M1
Conte, M1
Paternoster, G1
Martinez, B1
Pinelli, F1
Frontini, M1
Zucchetti, MC1
Pappalardo, F1
Amantea, B1
Camata, A1
Pisano, A1
Verdecchia, C1
Dal Checco, E1
Cariello, C1
Faita, L1
Baldassarri, R1
Scandroglio, AM1
Saleh, O1
Lembo, R1
Calabrò, MG2
Bellomo, R1
Landoni, G2
Cobas, M1
Paparcuri, G1
De La Pena, M1
Cudemus, G1
Barquist, E1
Varon, A1
Mathur, VS1
Morelli, A1
Rocco, M1
Conti, G1
Orecchioni, A1
Alberto De Blasi, R1
Coluzzi, F1
Pietropaoli, P1
Samuels, J1
Finkel, K1
Gubert, M1
Johnson, T1
Shaw, A1
Brienza, N1
Malcangi, V1
Dalfino, L1
Trerotoli, P1
Guagliardi, C1
Bortone, D1
Faconda, G1
Ribezzi, M1
Ancona, G1
Bruno, F1
Fiore, T1
Murray, PT1
Ricci, Z1
Ronco, C1
Biondi-Zoccai, GG1
Tumlin, JA1
De Luca, M1
Ranucci, M1
Moffett, BS1
Mott, AR1
Nelson, DP1
Goldstein, SL1
Jefferies, JL1
Aurora, RN1
Milite, F1
Carlon, G1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Efficacy of Fenoldopam in Reducing the Need for Renal Replacement Therapy After Cardiac Surgery. A Randomized Controlled Study.[NCT00621790]Phase 3667 participants (Actual)Interventional2008-02-29Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for fenoldopam and Critical Illness

ArticleYear
The role of the DA1 receptor agonist fenoldopam in the management of critically ill, transplant, and hypertensive patients.
    Reviews in cardiovascular medicine, 2003, Volume: 4 Suppl 1

    Topics: Critical Illness; Dopamine Agonists; Fenoldopam; Humans; Hypertension; Kidney Diseases; Liver Transp

2003
Beneficial impact of fenoldopam in critically ill patients with or at risk for acute renal failure: a meta-analysis of randomized clinical trials.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2007, Volume: 49, Issue:1

    Topics: Acute Kidney Injury; Critical Illness; Fenoldopam; Humans; Randomized Controlled Trials as Topic; Ri

2007

Trials

5 trials available for fenoldopam and Critical Illness

ArticleYear
Effect of fenoldopam on use of renal replacement therapy among patients with acute kidney injury after cardiac surgery: a randomized clinical trial.
    JAMA, 2014, Dec-03, Volume: 312, Issue:21

    Topics: Acute Kidney Injury; Aged; Cardiac Surgical Procedures; Creatinine; Critical Illness; Double-Blind M

2014
Fenoldopam in critically ill patients with early renal dysfunction. A crossover study.
    Cardiovascular therapeutics, 2011, Volume: 29, Issue:4

    Topics: Acute Kidney Injury; Adult; Aged; Critical Illness; Cross-Over Studies; Dopamine Agonists; Double-Bl

2011
Monitoring renal oxygen supply in critically-ill patients using urinary oxygen tension.
    Anesthesia and analgesia, 2003, Volume: 97, Issue:6

    Topics: Adolescent; Blood Urea Nitrogen; Child; Creatinine; Critical Illness; Diuresis; Dopamine Agonists; E

2003
A comparison between fenoldopam and low-dose dopamine in early renal dysfunction of critically ill patients.
    Critical care medicine, 2006, Volume: 34, Issue:3

    Topics: Acute Kidney Injury; Aged; Critical Illness; Dopamine; Dopamine Agonists; Female; Fenoldopam; Humans

2006
'Renal-dose' fenoldopam for early-stage renal dysfunction in critically ill patients.
    Nature clinical practice. Nephrology, 2006, Volume: 2, Issue:10

    Topics: Adult; Critical Illness; Dopamine Agonists; Fenoldopam; Humans; Kidney Diseases; Prospective Studies

2006

Other Studies

4 other studies available for fenoldopam and Critical Illness

ArticleYear
Effect of fenoldopam mesylate in critically ill patients at risk for acute renal failure is dose dependent.
    Renal failure, 2005, Volume: 27, Issue:1

    Topics: Acute Kidney Injury; Adult; Aged; Critical Illness; Dopamine Agonists; Dose-Response Relationship, D

2005
Fenoldopam: renal-dose dopamine redux?
    Critical care medicine, 2006, Volume: 34, Issue:3

    Topics: Acute Kidney Injury; Critical Illness; Dopamine; Dopamine Agonists; Fenoldopam; Humans; Infusions, I

2006
Renal effects of fenoldopam in critically ill pediatric patients: A retrospective review.
    Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2008, Volume: 9, Issue:4

    Topics: Adolescent; Adult; Child; Child, Preschool; Creatinine; Critical Illness; Diuresis; Dopamine Agonist

2008
Preventing renal failure in critically ill patients.
    Critical care medicine, 1999, Volume: 27, Issue:9

    Topics: Acute Kidney Injury; Critical Illness; Dopamine Agonists; Fenoldopam; Humans; Renal Circulation

1999