Page last updated: 2024-10-27

fenoldopam and Chronic Kidney Failure

fenoldopam has been researched along with Chronic Kidney Failure in 10 studies

Fenoldopam: A dopamine D1 receptor agonist that is used as an antihypertensive agent. It lowers blood pressure through arteriolar vasodilation.

Research Excerpts

ExcerptRelevanceReference
"These results show that for advanced chronic renal failure, fenoldopam has diuretic and natriuretic properties that could be of clinical relevance."1.28Diuretic and natriuretic properties of fenoldopam in chronic renal failure. ( Alcázar, JM; Alvarez, C; Andrés, A; García-Robles, R; Martínez, J; Oliet, A; Rodicio, JL; Ruilope, LM; Sancho, J, 1989)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19901 (10.00)18.7374
1990's4 (40.00)18.2507
2000's5 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Stone, GW1
McCullough, PA1
Tumlin, JA1
Lepor, NE1
Madyoon, H1
Murray, P1
Wang, A1
Chu, AA1
Schaer, GL1
Stevens, M1
Wilensky, RL1
O'Neill, WW1
Cohen, MG1
Ng, MK1
Tremmel, J1
Fitzgerald, PJ1
Fearon, WF1
Barr, LF1
Kolodner, K1
Robles, RG1
Villa, E1
Andres, A2
Martinez, J2
Ruilope, LM2
Sancho, JM1
Kini, AS1
Mitre, CA1
Kamran, M1
Suleman, J1
Kim, M1
Duffy, ME1
Marmur, JD1
Sharma, SK1
Girbes, AR1
van Veldhuisen, DJ1
Smit, AJ2
de Fijter, CW1
Comans, EF1
de Vries, PM1
Oe, PL1
Roos, JC1
Streurman, O1
Donker, AJ1
Brooks, DP1
Goldstein, R1
Koster, PF1
DePalma, PD1
DiCristo, M1
Karpinski, K1
Hyneck, M1
García-Robles, R1
Alcázar, JM1
Alvarez, C1
Oliet, A1
Sancho, J1
Rodicio, JL1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Renal Insufficiency Following Contrast Media Administration Trial II (Remedial II): The RenalGuard System in High-Risk Patients for Contrast-Induced Acute Kidney Injury[NCT01098032]Phase 3294 participants (Actual)Interventional2009-01-31Completed
N-acetylcysteine and Fenoldopam Protect the Renal Function of Patients With Chronic Renal Insufficiency Undergoing Cardiac Surgery.[NCT00122018]Phase 280 participants Interventional2002-05-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Number of Participants With Contrast-induced Acute Kidney Injury

The primary outcome measure will be the rate of development of CI-AKI in the 2 study arms (number of participants). CI-AKI is defined as an increase in the serum creatinine concentration >=0.3 mg/dL from the baseline value at 48 hours after administration of the contrast media or the need for dialysis. (NCT01098032)
Timeframe: at 48 hours following contrast exposure

Interventionparticipants (Number)
Systemic Alone Therapy Group146
RenalGuard System Group146

Trials

2 trials available for fenoldopam and Chronic Kidney Failure

ArticleYear
Fenoldopam mesylate for the prevention of contrast-induced nephropathy: a randomized controlled trial.
    JAMA, 2003, Nov-05, Volume: 290, Issue:17

    Topics: Adult; Aged; Angiography; Angioplasty, Balloon, Coronary; Contrast Media; Creatinine; Dopamine Agoni

2003
N-acetylcysteine and fenoldopam protect the renal function of patients with chronic renal insufficiency undergoing cardiac surgery.
    Critical care medicine, 2008, Volume: 36, Issue:5

    Topics: Acetylcysteine; Aged; Cardiac Surgical Procedures; Dopamine Agonists; Double-Blind Method; Female; F

2008

Other Studies

8 other studies available for fenoldopam and Chronic Kidney Failure

ArticleYear
First experience with intra-renal fenoldopam in a patient with heart failure.
    The Journal of invasive cardiology, 2005, Volume: 17, Issue:5

    Topics: Aged; Cardiac Catheterization; Catheterization; Electrocardiography; Equipment Design; Equipment Saf

2005
Selective renal arterial infusion of fenoldopam for the prevention of contrast-induced nephropathy.
    Journal of interventional cardiology, 2006, Volume: 19, Issue:1

    Topics: Acute Kidney Injury; Catheterization; Contrast Media; Fenoldopam; Humans; Kidney Failure, Chronic; M

2006
Natriuretic effects of dopamine agonist drugs in models of reduced renal mass.
    Journal of cardiovascular pharmacology, 1993, Volume: 22 Suppl 2

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adult; Aged; Animals; Blood Pressure; Di

1993
Changing trends in incidence and predictors of radiographic contrast nephropathy after percutaneous coronary intervention with use of fenoldopam.
    The American journal of cardiology, 2002, Apr-15, Volume: 89, Issue:8

    Topics: Aged; Atherectomy, Coronary; Cardiac Catheterization; Contrast Media; Diabetic Nephropathies; Dopami

2002
Dopamine agonists, a new perspective in cardiovascular therapy?
    The Netherlands journal of medicine, 1991, Volume: 39, Issue:1-2

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Deoxyepinephrine; Dopamine Agents; Fenol

1991
The effect of fenoldopam on renal haemodynamics and natriuresis in chronic renal failure.
    The Netherlands journal of medicine, 1990, Volume: 36, Issue:5-6

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Administration, Oral; Adult; Aged; Aldos

1990
Effect of fenoldopam in dogs with spontaneous renal insufficiency.
    European journal of pharmacology, 1990, Aug-02, Volume: 184, Issue:1

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Administration, Oral; Animals; Creatinin

1990
Diuretic and natriuretic properties of fenoldopam in chronic renal failure.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1989, Volume: 7, Issue:6

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Blood Pressure; Diuresis; Dopamine Agent

1989