Page last updated: 2024-10-27

fenoldopam and Anesthesia

fenoldopam has been researched along with Anesthesia in 15 studies

Fenoldopam: A dopamine D1 receptor agonist that is used as an antihypertensive agent. It lowers blood pressure through arteriolar vasodilation.

Anesthesia: A state characterized by loss of feeling or sensation. This depression of nerve function is usually the result of pharmacologic action and is induced to allow performance of surgery or other painful procedures.

Research Excerpts

ExcerptRelevanceReference
" After the administration of SK&F R-83566, the renal vasodilator responses to fenoldopam were antagonized markedly with an approximate 30-fold rightward shift in the log dose-response curve, whereas the renal vasodilator responses to dopamine were abolished completely and converted into small vasoconstrictor responses."1.27Comparison of the effects of the novel inotropic agent, ibopamine, with epinine, dopamine and fenoldopam on renal vascular dopamine receptors in the anesthetized dog. ( Nichols, AJ; Ruffolo, RR; Shebuski, RJ; Smith, JM, 1987)
"Fenoldopam (SK&F 82526) is a potent agonist at DA1 receptors, with much less agonist activity at the DA2 subtype or at alpha and beta adrenoceptors."1.27Hemodynamic effects of selective dopamine receptor agonists in the rat and dog. ( Blumberg, AL; DeMarinis, RM; Harvey, CA; Hieble, JP; Owen, DA; Valocik, RE, 1987)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19908 (53.33)18.7374
1990's4 (26.67)18.2507
2000's3 (20.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Oliver, WC1
Nuttall, GA1
Cherry, KJ1
Decker, PA1
Bower, T1
Ereth, MH1
Salomone, LJ1
Howell, NL1
McGrath, HE1
Kemp, BA1
Keller, SR1
Gildea, JJ1
Felder, RA1
Carey, RM1
Seymour, AA1
Blaine, EH1
Damase-Michel, C1
Montastruc, JL1
Tran, MA1
Halpenny, M1
Lakshmi, S1
O'Donnell, A1
O'Callaghan-Enright, S1
O'Connell, D1
Shorten, G1
Clark, KL1
Robertson, MJ1
Drew, GM1
Pellissier, G1
Demenge, P1
Brooks, DP1
DePalma, PD1
Cyronak, MJ1
Karpinski, K1
Weinstock, J1
Hegde, SS1
Lokhandwala, MF2
Kopia, GA1
Valocik, RE2
Shebuski, RJ2
Fujita, T1
Smith, JM2
Kopaciewicz, LJ1
Blumberg, AL2
Hieble, JP2
Sengupta, S1
Nichols, AJ1
Ruffolo, RR1
Owen, DA1
Harvey, CA1
DeMarinis, RM1
Cavero, I1
Thiry, C1
Pratz, J1
Lawson, K1

Trials

2 trials available for fenoldopam and Anesthesia

ArticleYear
A comparison of fenoldopam with dopamine and sodium nitroprusside in patients undergoing cross-clamping of the abdominal aorta.
    Anesthesia and analgesia, 2006, Volume: 103, Issue:4

    Topics: Aged; Aged, 80 and over; Anesthesia; Antihypertensive Agents; Aorta, Abdominal; Blood Pressure; Dopa

2006
The effects of fenoldopam on coronary conduit blood flow after coronary artery bypass graft surgery.
    Journal of cardiothoracic and vascular anesthesia, 2001, Volume: 15, Issue:1

    Topics: Aged; Anesthesia; Blood Pressure; Coronary Artery Bypass; Coronary Circulation; Double-Blind Method;

2001

Other Studies

13 other studies available for fenoldopam and Anesthesia

ArticleYear
Intrarenal dopamine D1-like receptor stimulation induces natriuresis via an angiotensin type-2 receptor mechanism.
    Hypertension (Dallas, Tex. : 1979), 2007, Volume: 49, Issue:1

    Topics: Anesthesia; Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Benzazepines; Diuresis

2007
A comparison of some renal and cardiovascular effects of a prostaglandin analog, SKF 82526 and ibopamine in anesthetized dogs.
    Archives internationales de pharmacodynamie et de therapie, 1984, Volume: 269, Issue:2

    Topics: Anesthesia; Animals; Benzazepines; Blood Pressure; Deoxyepinephrine; Dogs; Dopamine; Electrolytes; F

1984
Effects of dopaminergic drugs on the sympathoadrenal system.
    Hypertension research : official journal of the Japanese Society of Hypertension, 1995, Volume: 18 Suppl 1

    Topics: Adrenal Glands; Anesthesia; Animals; Cisterna Magna; Dogs; Dopamine Agents; Dopamine Agonists; Dopam

1995
Do renal tubular dopamine receptors mediate dopamine-induced diuresis in the anesthetized cat?
    Journal of cardiovascular pharmacology, 1991, Volume: 17, Issue:2

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Anesthesia; Animals; Benzazepines; Cats;

1991
Hypotensive and bradycardic effects elicited by spinal dopamine receptor stimulation: effects of D1 and D2 receptor agonists and antagonists.
    Journal of cardiovascular pharmacology, 1991, Volume: 18, Issue:4

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Anesthesia; Animals; Antipsychotic Agent

1991
Pharmacology of SK&F R-105058 and R-106114, N-ethyl carbamate ester prodrugs of fenoldopam.
    Pharmacology, 1990, Volume: 41, Issue:5

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Anesthesia; Animals; Benzazepines; Biotr

1990
Involvement of cyclic-AMP in the hypotensive response to fenoldopam but not to quinpirole in the anaesthetized rat.
    Journal of autonomic pharmacology, 1988, Volume: 8, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Acetylcholine; Anesthesia; Animals; Benzazepines; Blood Pressure; Cycli

1988
Demonstration of specific dopamine-1 receptor-mediated coronary vasodilation in the anesthetized dog.
    The Journal of pharmacology and experimental therapeutics, 1989, Volume: 248, Issue:1

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Anesthesia; Angina Pectoris; Animals; Be

1989
Suppression of sympathetic ganglionic neurotransmission by the selective dopamine-1 receptor agonist fenoldopam (SK&F 82526) in the anesthetized dog.
    The Journal of pharmacology and experimental therapeutics, 1985, Volume: 235, Issue:3

    Topics: Anesthesia; Animals; Azepines; Benzazepines; Blood Pressure; Dogs; Electric Stimulation; Female; Fen

1985
Characterization of the hypotensive action of dopamine receptor agonists fenoldopam and quinpirole in anaesthetized rats.
    Journal of autonomic pharmacology, 1985, Volume: 5, Issue:4

    Topics: Anesthesia; Animals; Antihypertensive Agents; Benzazepines; Blood Pressure; Ergolines; Fenoldopam; H

1985
Comparison of the effects of the novel inotropic agent, ibopamine, with epinine, dopamine and fenoldopam on renal vascular dopamine receptors in the anesthetized dog.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 242, Issue:2

    Topics: Anesthesia; Animals; Benzazepines; Blood Vessels; Cardiotonic Agents; Deoxyepinephrine; Dogs; Dopami

1987
Hemodynamic effects of selective dopamine receptor agonists in the rat and dog.
    Clinical and experimental hypertension. Part A, Theory and practice, 1987, Volume: 9, Issue:5-6

    Topics: Anesthesia; Animals; Antihypertensive Agents; Benzazepines; Dogs; Female; Fenoldopam; Hemodynamics;

1987
Cardiovascular characterization of DA-1 and DA-2 dopamine receptor agonists in anesthetized rats.
    Clinical and experimental hypertension. Part A, Theory and practice, 1987, Volume: 9, Issue:5-6

    Topics: Anesthesia; Animals; Benzazepines; Blood Pressure; Drug Interactions; Electric Stimulation; Ergoline

1987