Page last updated: 2024-08-24

fenofibric acid and Diabetic Retinopathy

fenofibric acid has been researched along with Diabetic Retinopathy in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's9 (90.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Bourne, PC; Dou, X; Duerfeldt, AS; Ma, JX; Nath, D; Nurmemmedov, E; Shin, H1
Chen, Q; Deng, G; Du, Y; Ma, JX; Ma, X; Matlock, G; Meng, T; Qiu, F; Shao, Y; Wang, X; Wu, W; Xu, Q; Zhou, K1
Bogdanov, P; Carvalho, AR; Corraliza, L; Hernández, C; Simó, R1
Ansquer, JC; Aubonnet, P; MacuFEN Study Investigators, FT; Massin, P; Peto, T1
Nie, J; Wang, F; Wang, H; Zhang, C1
Garcia-Ramírez, M; Hernández, C; Palomer, X; Simó, R; Vázquez-Carrera, M1
Hernández, C; Kim, D; Roy, S; Simó, R1
Bose, N; Kishan, AU; Modjtahedi, BS; Morse, L; Papakostas, TD; Vavvas, DG1
Liu, IM; Liu, WY; Tzeng, TF1
Corraliza, L; Garcia-Ramírez, M; Hernández, C; Simó, R; Villarroel, M1

Reviews

2 review(s) available for fenofibric acid and Diabetic Retinopathy

ArticleYear
Protective factors in diabetic retinopathy: focus on blood-retinal barrier.
    Discovery medicine, 2014, Volume: 18, Issue:98

    Topics: Animals; Blood-Retinal Barrier; Diabetic Retinopathy; Erythropoietin; Fenofibrate; Humans; Insulin-Like Growth Factor Binding Protein 3; Macular Edema; Protective Factors; Pyrazines; Sitagliptin Phosphate; Triazoles; Vascular Endothelial Growth Factor A

2014
Lipids and Diabetic Retinopathy.
    Seminars in ophthalmology, 2016, Volume: 31, Issue:1-2

    Topics: Diabetic Retinopathy; Fenofibrate; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Lipids

2016

Trials

1 trial(s) available for fenofibric acid and Diabetic Retinopathy

ArticleYear
Effects of fenofibric acid on diabetic macular edema: the MacuFen study.
    Ophthalmic epidemiology, 2014, Volume: 21, Issue:5

    Topics: Anticholesteremic Agents; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Double-Blind Method; Female; Fenofibrate; Humans; Macula Lutea; Macular Edema; Male; Middle Aged; Prospective Studies; Tomography, Optical Coherence; Triglycerides; Visual Acuity

2014

Other Studies

7 other study(ies) available for fenofibric acid and Diabetic Retinopathy

ArticleYear
Evolution of a 4-Benzyloxy-benzylamino Chemotype to Provide Efficacious, Potent, and Isoform Selective PPARα Agonists as Leads for Retinal Disorders.
    Journal of medicinal chemistry, 2020, 03-26, Volume: 63, Issue:6

    Topics: Animals; Benzylamines; Capillary Permeability; Cell Line; Diabetic Retinopathy; Disease Models, Animal; Drug Design; Drug Discovery; Humans; PPAR alpha; Rats; Retinal Diseases; Streptozocin

2020
Fenofibrate-Loaded Biodegradable Nanoparticles for the Treatment of Experimental Diabetic Retinopathy and Neovascular Age-Related Macular Degeneration.
    Molecular pharmaceutics, 2019, 05-06, Volume: 16, Issue:5

    Topics: Animals; Capillary Permeability; Choroidal Neovascularization; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Drug Delivery Systems; Drug Liberation; Fenofibrate; Hypolipidemic Agents; Intercellular Adhesion Molecule-1; Leukostasis; Mice; Mice, Knockout; Nanoparticles; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Inbred BN; Retina; Streptozocin; Tissue Distribution; Vascular Endothelial Growth Factor A; Wet Macular Degeneration

2019
Effect of fenofibrate on retinal neurodegeneration in an experimental model of type 2 diabetes.
    Acta diabetologica, 2015, Volume: 52, Issue:1

    Topics: Animals; Apoptosis; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Disease Models, Animal; Excitatory Amino Acid Transporter 1; Fenofibrate; Humans; Male; Mice; Retinal Degeneration

2015
Fenofibrate prevents the disruption of the outer blood retinal barrier through downregulation of NF-κB activity.
    Acta diabetologica, 2016, Volume: 53, Issue:1

    Topics: Blood-Retinal Barrier; Capillary Permeability; Cells, Cultured; Cytokines; Diabetic Retinopathy; Down-Regulation; Fenofibrate; Humans; Interleukin-1beta; Interleukin-6; Macular Edema; Retinal Pigment Epithelium; Signal Transduction; Transcription Factor RelA

2016
Beneficial effects of fenofibric acid on overexpression of extracellular matrix components, COX-2, and impairment of endothelial permeability associated with diabetic retinopathy.
    Experimental eye research, 2015, Volume: 140

    Topics: Animals; Anticholesteremic Agents; Blotting, Western; Capillary Permeability; Cells, Cultured; Collagen Type IV; Cyclooxygenase 2; Diabetic Retinopathy; Endothelium, Vascular; Fenofibrate; Fibronectins; Fluorescein-5-isothiocyanate; Fluorescent Antibody Technique, Indirect; Microscopy, Fluorescence; Rats; Retinal Vessels; Zonula Occludens-1 Protein

2015
Zerumbone, a Bioactive Sesquiterpene, Ameliorates Diabetes-Induced Retinal Microvascular Damage through Inhibition of Phospho-p38 Mitogen-Activated Protein Kinase and Nuclear Factor-κB Pathways.
    Molecules (Basel, Switzerland), 2016, Dec-11, Volume: 21, Issue:12

    Topics: Animals; Capillary Permeability; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Fenofibrate; Glycation End Products, Advanced; Male; Microvessels; p38 Mitogen-Activated Protein Kinases; Rats; Rats, Wistar; Retina; Retinal Vessels; Sesquiterpenes; Signal Transduction; Streptozocin; Transcription Factor RelA

2016
Fenofibric acid prevents retinal pigment epithelium disruption induced by interleukin-1β by suppressing AMP-activated protein kinase (AMPK) activation.
    Diabetologia, 2011, Volume: 54, Issue:6

    Topics: Aged; AMP-Activated Protein Kinases; Biological Transport; Blood-Retinal Barrier; Cell Line; Cell Membrane Permeability; Dextrans; Diabetic Retinopathy; Dose-Response Relationship, Drug; Fenofibrate; Fluorescein-5-isothiocyanate; Glucose; Humans; Hypolipidemic Agents; Interleukin-1beta; Macular Edema; Retinal Pigment Epithelium; Tight Junctions

2011