Page last updated: 2024-10-27

fenofibrate and Weight Loss

fenofibrate has been researched along with Weight Loss in 11 studies

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Weight Loss: Decrease in existing BODY WEIGHT.

Research Excerpts

ExcerptRelevanceReference
"In subjects with obesity, diabetes and coronary artery disease, circulating levels of leptin increased while that of adiponectin is decreased."7.74The effects of physiological and pharmacological weight loss on adiponectin and leptin mRNA levels in the rat epididymal adipose tissue. ( Fatani, S; Hunter, L; Naderali, EK; Telles, M, 2008)
" We assessed the effects of rimonabant, alone and in combination with fenofibrate or ezetimibe, on adipokine levels in obese/overweight patients with dyslipidemia."5.14Effects of rimonabant, as monotherapy and in combination with fenofibrate or ezetimibe, on plasma adipokine levels: a pilot study. ( Derdemezis, CS; Elisaf, M; Florentin, M; Liberopoulos, EN; Tellis, CC; Tselepis, A, 2010)
" Fenofibrate, a selective peroxisome proliferator-activated receptor α (PPAR-α) agonist, elicits weight loss in animal models."3.81PPAR-α agonist elicits metabolically active brown adipocytes and weight loss in diet-induced obese mice. ( Aguila, MB; Bringhenti, I; Mandarim-de-Lacerda, CA; Penna-de-Carvalho, A; Rachid, TL; Souza-Mello, V, 2015)
"In subjects with obesity, diabetes and coronary artery disease, circulating levels of leptin increased while that of adiponectin is decreased."3.74The effects of physiological and pharmacological weight loss on adiponectin and leptin mRNA levels in the rat epididymal adipose tissue. ( Fatani, S; Hunter, L; Naderali, EK; Telles, M, 2008)
"The attenuation of diabetic kidney disease (DKD) by metabolic surgery is enhanced by pharmacotherapy promoting renal fatty acid oxidation (FAO)."1.72Dietary restriction and medical therapy drives PPARα-regulated improvements in early diabetic kidney disease in male rats. ( Abdelaal, M; Abrahamsson, S; Brennan, EP; Chuah, YHD; Docherty, NG; Eckhardt, H; Elliott, JA; Fändriks, L; Fearon, N; Godson, C; Hutter, M; le Roux, CW; Malmodin, D; Martin, WP; Nair, M; Pedersen, A, 2022)
"Amiodarone treated PPARα(-/-) mice exhibited significantly greater weight loss and higher serum aspartate aminotransferase (AST) compared to PPARα(+/+) mice."1.36Influence of peroxisome proliferator-activated receptor-alpha (PPARα) activity on adverse effects associated with amiodarone exposure in mice. ( Ernst, MC; Pollak, PT; Sinal, CJ, 2010)
"Fenofibrate treatment markedly increased circulating resistin levels on both diets and adiponectin levels in chow-fed mice only."1.33Improvement of insulin sensitivity after peroxisome proliferator-activated receptor-alpha agonist treatment is accompanied by paradoxical increase of circulating resistin levels. ( Dolinkova, M; Haluzik, M; Haluzik, MM; Haluzikova, D; Horinek, A; Housa, D; Kumstyrova, T; Lacinova, Z; Vernerova, Z, 2006)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (9.09)18.2507
2000's5 (45.45)29.6817
2010's4 (36.36)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Sashidhara, KV1
Kumar, M1
Sonkar, R1
Singh, BS1
Khanna, AK1
Bhatia, G1
Martin, WP1
Nair, M1
Chuah, YHD1
Malmodin, D1
Pedersen, A1
Abrahamsson, S1
Hutter, M1
Abdelaal, M1
Elliott, JA1
Fearon, N1
Eckhardt, H1
Godson, C1
Brennan, EP1
Fändriks, L1
le Roux, CW1
Docherty, NG1
Rachid, TL1
Penna-de-Carvalho, A1
Bringhenti, I1
Aguila, MB1
Mandarim-de-Lacerda, CA1
Souza-Mello, V1
Florentin, M1
Liberopoulos, EN2
Tellis, CC1
Derdemezis, CS1
Elisaf, M1
Tselepis, A1
Ernst, MC1
Sinal, CJ1
Pollak, PT1
Vikramadithyan, RK1
Hiriyan, J1
Suresh, J1
Gershome, C1
Babu, RK1
Misra, P1
Rajagopalan, R1
Chakrabarti, R1
Iglesias, P1
Alvarez Fidalgo, P1
Codoceo, R1
Díez, JJ1
Athyros, VG1
Mikhailidis, DP1
Didangelos, TP1
Giouleme, OI1
Karagiannis, A1
Kakafika, AI1
Tziomalos, K1
Burroughs, AK1
Elisaf, MS1
Haluzik, MM1
Lacinova, Z1
Dolinkova, M1
Haluzikova, D1
Housa, D1
Horinek, A1
Vernerova, Z1
Kumstyrova, T1
Haluzik, M1
Naderali, EK1
Fatani, S1
Telles, M1
Hunter, L1
Muls, E1
Van Gaal, L1
Autier, P1
Vansant, G1

Trials

2 trials available for fenofibrate and Weight Loss

ArticleYear
Effects of rimonabant, as monotherapy and in combination with fenofibrate or ezetimibe, on plasma adipokine levels: a pilot study.
    Angiology, 2010, Volume: 61, Issue:4

    Topics: Adipokines; Adult; Aged; Azetidines; Body Mass Index; Diet, Reducing; Drug Therapy, Combination; Dys

2010
Effect of multifactorial treatment on non-alcoholic fatty liver disease in metabolic syndrome: a randomised study.
    Current medical research and opinion, 2006, Volume: 22, Issue:5

    Topics: Anti-Obesity Agents; Atorvastatin; Diet, Fat-Restricted; Drug Therapy, Combination; Dyslipidemias; F

2006

Other Studies

9 other studies available for fenofibrate and Weight Loss

ArticleYear
Indole-based fibrates as potential hypolipidemic and antiobesity agents.
    Journal of medicinal chemistry, 2012, Mar-22, Volume: 55, Issue:6

    Topics: Animals; Anti-Obesity Agents; Bile Acids and Salts; Butyrates; Dietary Fats; Fatty Liver; Feces; Fee

2012
Dietary restriction and medical therapy drives PPARα-regulated improvements in early diabetic kidney disease in male rats.
    Clinical science (London, England : 1979), 2022, 11-11, Volume: 136, Issue:21

    Topics: Animals; Diabetes Mellitus; Diabetic Nephropathies; Fenofibrate; Kidney; Male; Niacinamide; PPAR alp

2022
PPAR-α agonist elicits metabolically active brown adipocytes and weight loss in diet-induced obese mice.
    Cell biochemistry and function, 2015, Volume: 33, Issue:4

    Topics: Adipocytes, Brown; Adipose Tissue; Animals; Biomarkers; Diet; Energy Metabolism; Fenofibrate; Hypoli

2015
Influence of peroxisome proliferator-activated receptor-alpha (PPARα) activity on adverse effects associated with amiodarone exposure in mice.
    Pharmacological research, 2010, Volume: 62, Issue:5

    Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Aspartate Aminotransferases; Dose-Response Relationship

2010
DRF 2655: a unique molecule that reduces body weight and ameliorates metabolic abnormalities.
    Obesity research, 2003, Volume: 11, Issue:2

    Topics: 3T3 Cells; Adipocytes; Animals; Anti-Obesity Agents; Cell Differentiation; Cell Line; Cholesterol; C

2003
Lipoatrophic diabetes in an elderly woman: clinical course and serum adipocytokine concentrations.
    Endocrine journal, 2004, Volume: 51, Issue:3

    Topics: Adiponectin; Aged; Blood Glucose; Cytokines; Diabetes Mellitus, Lipoatrophic; Diabetes Mellitus, Typ

2004
Improvement of insulin sensitivity after peroxisome proliferator-activated receptor-alpha agonist treatment is accompanied by paradoxical increase of circulating resistin levels.
    Endocrinology, 2006, Volume: 147, Issue:9

    Topics: Adiponectin; Adipose Tissue; Animals; Blood Glucose; Diet; Dietary Carbohydrates; Fatty Acids, Nones

2006
The effects of physiological and pharmacological weight loss on adiponectin and leptin mRNA levels in the rat epididymal adipose tissue.
    European journal of pharmacology, 2008, Jan-28, Volume: 579, Issue:1-3

    Topics: Adiponectin; Adipose Tissue; Animals; Epididymis; Fatty Acids, Nonesterified; Fenofibrate; Gene Expr

2008
Effects of initial BMI and on-treatment weight change on the lipid-lowering efficacy of fibrates.
    International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity, 1997, Volume: 21, Issue:2

    Topics: Body Mass Index; Clofibric Acid; Female; Fenofibrate; Fibric Acids; Gemfibrozil; Humans; Hypercholes

1997