Page last updated: 2024-10-27

fenofibrate and Proteinuria

fenofibrate has been researched along with Proteinuria in 11 studies

Pharmavit: a polyvitamin product, comprising vitamins A, D2, B1, B2, B6, C, E, nicotinamide, & calcium pantothene; may be a promising agent for application to human populations exposed to carcinogenic and genetic hazards of ionizing radiation; RN from CHEMLINE

Proteinuria: The presence of proteins in the urine, an indicator of KIDNEY DISEASES.

Research Excerpts

ExcerptRelevanceReference
"Fenofibrate prevented the increase in BP in 4-5 week old SHRSP, reduced BP in 25 week old SHRSP, but had no effect on BP in normotensive SD rats."5.31Fenofibrate lowers blood pressure in two genetic models of hypertension. ( Quest, DW; Shatara, RK; Wilson, TW, 2000)
" In the salt-loaded spontaneously hypertensive stroke-prone rat (SHRSP), a model of cardiac hypertrophy and nephropathy that shows mitochondrial alterations in the myocardium, we evaluated the cardiorenal effects of fenofibrate, a peroxisome proliferator-activated receptor alpha (PPARα) agonist that acts by modulating mitochondrial and peroxisomal fatty acid oxidation."3.88Fenofibrate attenuates cardiac and renal alterations in young salt-loaded spontaneously hypertensive stroke-prone rats through mitochondrial protection. ( Abbate, M; Castiglioni, L; Crestani, M; Fiaschè, M; Fiordaliso, F; Foray, C; Gelosa, P; Giudici, M; Guerrini, U; Mitro, N; Pignieri, A; Rottoli, D; Sironi, L; Tremoli, E; Zoja, C, 2018)
"Inducing renal cytochrome P4504A (P4504A) activity with clofibrate prevents the development of hypertension in Dahl salt-sensitive (Dahl S) rats."3.70Effects of lipid-lowering agents in the Dahl salt-sensitive rat. ( Alonso-Galicia, M; Roman, RJ; Wilson, TW, 1998)
"The development of diabetic nephropathy was assessed biochemically and histologically."1.39Differential effects of low-dose fenofibrate treatment in diabetic rats with early onset nephropathy and established nephropathy. ( Balakumar, P; Kadian, S; Mahadevan, N, 2013)
"Treatment with fenofibrate (80 mg/kg/day, p."1.38The combined strategy with PPARα agonism and AT₁ receptor antagonism is not superior relative to their individual treatment approach in preventing the induction of nephropathy in the diabetic rat. ( Balakumar, P; Bishnoi, HK; Mahadevan, N, 2012)
"The development of diabetic nephropathy was assessed biochemically and histologically."1.36The low dose combination of fenofibrate and rosiglitazone halts the progression of diabetes-induced experimental nephropathy. ( Arora, MK; Balakumar, P; Reddy, K, 2010)
"Treatment with fenofibrate normalizes the altered lipid profile in diabetic rats, whereas benfotiamine treatment has no effect on lipid alteration in diabetic rats."1.35Ameliorative effect of combination of benfotiamine and fenofibrate in diabetes-induced vascular endothelial dysfunction and nephropathy in the rat. ( Balakumar, P; Chakkarwar, VA; Singh, M, 2009)
"Fenofibrate prevented the increase in BP in 4-5 week old SHRSP, reduced BP in 25 week old SHRSP, but had no effect on BP in normotensive SD rats."1.31Fenofibrate lowers blood pressure in two genetic models of hypertension. ( Quest, DW; Shatara, RK; Wilson, TW, 2000)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (9.09)18.2507
2000's3 (27.27)29.6817
2010's7 (63.64)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Castiglioni, L1
Pignieri, A1
Fiaschè, M1
Giudici, M1
Crestani, M1
Mitro, N1
Abbate, M1
Zoja, C1
Rottoli, D1
Foray, C1
Fiordaliso, F1
Guerrini, U1
Tremoli, E1
Sironi, L1
Gelosa, P1
Hu, Z1
Huang, S1
Wu, Y1
Liu, Y1
Liu, X1
Su, D1
Tao, Y1
Fu, P1
Zhang, X2
Peng, Z1
Zhang, S1
Yang, Y1
Balakumar, P4
Chakkarwar, VA1
Singh, M1
Arora, MK1
Reddy, K1
Zhou, Y1
Kong, X1
Zhao, P1
Yang, H1
Chen, L1
Miao, J1
Yang, J1
Ding, J1
Guan, Y1
Mori, K1
Mukoyama, M1
Nakao, K1
Bishnoi, HK1
Mahadevan, N2
Kadian, S1
Wilson, TW2
Alonso-Galicia, M1
Roman, RJ1
Shatara, RK1
Quest, DW1
Deighan, CJ1
Caslake, MJ1
McConnell, M1
Boulton-Jones, JM1
Packard, CJ1

Trials

1 trial available for fenofibrate and Proteinuria

ArticleYear
Comparative effects of cerivastatin and fenofibrate on the atherogenic lipoprotein phenotype in proteinuric renal disease.
    Journal of the American Society of Nephrology : JASN, 2001, Volume: 12, Issue:2

    Topics: Arteriosclerosis; Cholesterol, HDL; Cholesterol, LDL; Cholesterol, VLDL; Cross-Over Studies; Female;

2001

Other Studies

10 other studies available for fenofibrate and Proteinuria

ArticleYear
Fenofibrate attenuates cardiac and renal alterations in young salt-loaded spontaneously hypertensive stroke-prone rats through mitochondrial protection.
    Journal of hypertension, 2018, Volume: 36, Issue:5

    Topics: Acyl-CoA Dehydrogenase; Animals; Cardiomegaly; Cellular Senescence; Fenofibrate; Gene Expression; Hy

2018
Hereditary features, treatment, and prognosis of the lipoprotein glomerulopathy in patients with the APOE Kyoto mutation.
    Kidney international, 2014, Volume: 85, Issue:2

    Topics: Adolescent; Adult; Aged; Apolipoprotein E2; Biomarkers; Biopsy; Case-Control Studies; China; Creatin

2014
Ameliorative effect of combination of benfotiamine and fenofibrate in diabetes-induced vascular endothelial dysfunction and nephropathy in the rat.
    Molecular and cellular biochemistry, 2009, Volume: 320, Issue:1-2

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Glucose; Chelating Agents; Diabetes Mellitu

2009
The low dose combination of fenofibrate and rosiglitazone halts the progression of diabetes-induced experimental nephropathy.
    European journal of pharmacology, 2010, Jun-25, Volume: 636, Issue:1-3

    Topics: Animals; Blood Glucose; Blood Urea Nitrogen; Creatinine; Diabetic Nephropathies; Disease Models, Ani

2010
Peroxisome proliferator-activated receptor-α is renoprotective in doxorubicin-induced glomerular injury.
    Kidney international, 2011, Volume: 79, Issue:12

    Topics: Animals; Apoptosis; Caspase 3; Cell Line; Cytoprotection; Disease Models, Animal; Doxorubicin; Fenof

2011
PPAR-α transcriptional activity is required to combat doxorubicin-induced podocyte injury in mice.
    Kidney international, 2011, Volume: 79, Issue:12

    Topics: Animals; Apoptosis; Caspase 3; Cytoprotection; Disease Models, Animal; Doxorubicin; Fenofibrate; Kid

2011
The combined strategy with PPARα agonism and AT₁ receptor antagonism is not superior relative to their individual treatment approach in preventing the induction of nephropathy in the diabetic rat.
    Pharmacological research, 2012, Volume: 66, Issue:4

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Blood Glucose; Creatine

2012
Differential effects of low-dose fenofibrate treatment in diabetic rats with early onset nephropathy and established nephropathy.
    European journal of pharmacology, 2013, Jan-05, Volume: 698, Issue:1-3

    Topics: Animals; Blood Glucose; Blood Urea Nitrogen; Body Weight; Creatinine; Diabetic Nephropathies; Dose-R

2013
Effects of lipid-lowering agents in the Dahl salt-sensitive rat.
    Hypertension (Dallas, Tex. : 1979), 1998, Volume: 31, Issue:1 Pt 2

    Topics: Animals; Blood Pressure; Cholesterol; Clofibrate; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme Sy

1998
Fenofibrate lowers blood pressure in two genetic models of hypertension.
    Canadian journal of physiology and pharmacology, 2000, Volume: 78, Issue:5

    Topics: Animals; Blood Glucose; Blood Pressure; Fenofibrate; Hypertension; Hypolipidemic Agents; Male; Prote

2000