fenofibrate has been researched along with Parkinson Disease in 2 studies
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Parkinson Disease: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Parkinson's disease is a neurodegenerative disease, the etiology of which remains unknown, but some likely causes include oxidative stress, mitochondrial dysfunction and neuroinflammation." | 1.72 | Fenofibrate promotes neuroprotection in a model of rotenone-induced Parkinson's disease. ( Barbiero, JK; Bassani, T; Boschen, S; Da Cunha, C; Ramos, DC; Vital, MABF, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barbiero, JK | 1 |
| Ramos, DC | 1 |
| Boschen, S | 1 |
| Bassani, T | 1 |
| Da Cunha, C | 1 |
| Vital, MABF | 1 |
| Ferrazoli, EG | 1 |
| de Souza, HD | 1 |
| Nascimento, IC | 1 |
| Oliveira-Giacomelli, Á | 1 |
| Schwindt, TT | 1 |
| Britto, LR | 1 |
| Ulrich, H | 1 |
2 other studies available for fenofibrate and Parkinson Disease
| Article | Year |
|---|---|
Fenofibrate promotes neuroprotection in a model of rotenone-induced Parkinson's disease.
Topics: alpha-Synuclein; Animals; Disease Models, Animal; Dopamine; Dopaminergic Neurons; Fenofibrate; Male; | 2022 |
Brilliant Blue G, But Not Fenofibrate, Treatment Reverts Hemiparkinsonian Behavior and Restores Dopamine Levels in an Animal Model of Parkinson's Disease.
Topics: Animals; Blotting, Western; Disease Models, Animal; Dopamine; Fenofibrate; Male; Parkinson Disease; | 2017 |