Page last updated: 2024-10-27

fenofibrate and Overweight

fenofibrate has been researched along with Overweight in 8 studies

Pharmavit: a polyvitamin product, comprising vitamins A, D2, B1, B2, B6, C, E, nicotinamide, & calcium pantothene; may be a promising agent for application to human populations exposed to carcinogenic and genetic hazards of ionizing radiation; RN from CHEMLINE

Overweight: A status with BODY WEIGHT that is above certain standards. In the scale of BODY MASS INDEX, overweight is defined as having a BMI of 25.0-29.9 kg/m2. Overweight may or may not be due to increases in body fat (ADIPOSE TISSUE), hence overweight does not equal over fat.

Research Excerpts

ExcerptRelevanceReference
"To compare the effects of n-3 long chain polyunsaturated fatty acids (n-3 LCPUFA), with those of fenofibrate, on markers of inflammation and vascular function, and on the serum lipoprotein profile in overweight and obese subjects."9.16Comparison of the effects of n-3 long chain polyunsaturated fatty acids and fenofibrate on markers of inflammation and vascular function, and on the serum lipoprotein profile in overweight and obese subjects. ( Bragt, MC; Mensink, RP, 2012)
"To assess the effect of rimonabant, micronised fenofibrate and their combination on anthropometric and metabolic parameters in overweight/obese patients with dyslipidaemia."9.13Effect of rimonabant, micronised fenofibrate and their combination on cardiometabolic risk factors in overweight/obese patients: a pilot study. ( Elisaf, M; Filippatos, TD; Florentin, M; Kostara, C; Liberopoulos, EN; Mikhailidis, DP; Tselepis, A, 2008)
"We assessed the effect of orlistat and fenofibrate, alone or in combination, on plasma high-density lipoprotein (HDL) subfractions and plasma pre-beta1-HDL levels in overweight and obese subjects with metabolic syndrome (MetS)."9.13The effects of orlistat and fenofibrate, alone or in combination, on high-density lipoprotein subfractions and pre-beta1-HDL levels in obese patients with metabolic syndrome. ( Elisaf, MS; Filippatos, TD; Gazi, IF; Kiortsis, DN; Kostapanos, M; Liberopoulos, EN; Papavasiliou, EC; Tselepis, AD, 2008)
"The primary endpoint of this study was the effect of orlistat and fenofibrate, alone or in combination, on Lp-PLA(2) activity and LDL phenotype in overweight and obese patients (body mass index>28 kg/m(2)) with MetS."9.12The effect of orlistat and fenofibrate, alone or in combination, on small dense LDL and lipoprotein-associated phospholipase A2 in obese patients with metabolic syndrome. ( Athyros, VG; Elisaf, MS; Filippatos, TD; Gazi, IF; Kiortsis, DN; Liberopoulos, EN; Tselepis, AD, 2007)
"In an open-label randomised study (the FenOrli study) we assessed the effect of orlistat and fenofibrate treatment, alone or in combination on reversing the diagnosis of the MetS (primary end-point) as well as on anthropometric and metabolic parameters (secondary end-points) in overweight and obese patients with MetS but no diabetes."9.11Effect of orlistat, micronised fenofibrate and their combination on metabolic parameters in overweight and obese patients with the metabolic syndrome: the FenOrli study. ( Elisaf, MS; Filippatos, TD; Georgoula, M; Kiortsis, DN; Liberopoulos, EN; Mikhailidis, DP, 2005)
"Insulin sensitivity was unaffected by fenofibrate (P ≥ ."5.37Fenofibrate administration does not affect muscle triglyceride concentration or insulin sensitivity in humans. ( Bergman, BC; Eckel, RH; Howard, DJ; Hunerdosse, DM; Perreault, L, 2011)
"To compare the effects of n-3 long chain polyunsaturated fatty acids (n-3 LCPUFA), with those of fenofibrate, on markers of inflammation and vascular function, and on the serum lipoprotein profile in overweight and obese subjects."5.16Comparison of the effects of n-3 long chain polyunsaturated fatty acids and fenofibrate on markers of inflammation and vascular function, and on the serum lipoprotein profile in overweight and obese subjects. ( Bragt, MC; Mensink, RP, 2012)
"To assess the effect of rimonabant, micronised fenofibrate and their combination on anthropometric and metabolic parameters in overweight/obese patients with dyslipidaemia."5.13Effect of rimonabant, micronised fenofibrate and their combination on cardiometabolic risk factors in overweight/obese patients: a pilot study. ( Elisaf, M; Filippatos, TD; Florentin, M; Kostara, C; Liberopoulos, EN; Mikhailidis, DP; Tselepis, A, 2008)
"We assessed the effect of orlistat and fenofibrate, alone or in combination, on plasma high-density lipoprotein (HDL) subfractions and plasma pre-beta1-HDL levels in overweight and obese subjects with metabolic syndrome (MetS)."5.13The effects of orlistat and fenofibrate, alone or in combination, on high-density lipoprotein subfractions and pre-beta1-HDL levels in obese patients with metabolic syndrome. ( Elisaf, MS; Filippatos, TD; Gazi, IF; Kiortsis, DN; Kostapanos, M; Liberopoulos, EN; Papavasiliou, EC; Tselepis, AD, 2008)
"The primary endpoint of this study was the effect of orlistat and fenofibrate, alone or in combination, on Lp-PLA(2) activity and LDL phenotype in overweight and obese patients (body mass index>28 kg/m(2)) with MetS."5.12The effect of orlistat and fenofibrate, alone or in combination, on small dense LDL and lipoprotein-associated phospholipase A2 in obese patients with metabolic syndrome. ( Athyros, VG; Elisaf, MS; Filippatos, TD; Gazi, IF; Kiortsis, DN; Liberopoulos, EN; Tselepis, AD, 2007)
"In an open-label randomised study (the FenOrli study) we assessed the effect of orlistat and fenofibrate treatment, alone or in combination on reversing the diagnosis of the MetS (primary end-point) as well as on anthropometric and metabolic parameters (secondary end-points) in overweight and obese patients with MetS but no diabetes."5.11Effect of orlistat, micronised fenofibrate and their combination on metabolic parameters in overweight and obese patients with the metabolic syndrome: the FenOrli study. ( Elisaf, MS; Filippatos, TD; Georgoula, M; Kiortsis, DN; Liberopoulos, EN; Mikhailidis, DP, 2005)
"Insulin sensitivity was unaffected by fenofibrate (P ≥ ."1.37Fenofibrate administration does not affect muscle triglyceride concentration or insulin sensitivity in humans. ( Bergman, BC; Eckel, RH; Howard, DJ; Hunerdosse, DM; Perreault, L, 2011)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (50.00)29.6817
2010's3 (37.50)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Michielsen, CCJR1
Hangelbroek, RWJ1
Bragt, MCE1
Verheij, ER1
Wopereis, S1
Mensink, RP2
Afman, LA1
Montagner, A1
Polizzi, A1
Fouché, E1
Ducheix, S1
Lippi, Y1
Lasserre, F1
Barquissau, V1
Régnier, M1
Lukowicz, C1
Benhamed, F1
Iroz, A1
Bertrand-Michel, J1
Al Saati, T1
Cano, P1
Mselli-Lakhal, L1
Mithieux, G1
Rajas, F1
Lagarrigue, S1
Pineau, T1
Loiseau, N1
Postic, C1
Langin, D1
Wahli, W1
Guillou, H1
Florentin, M1
Liberopoulos, EN4
Filippatos, TD4
Kostara, C1
Tselepis, A1
Mikhailidis, DP2
Elisaf, M1
Perreault, L1
Bergman, BC1
Hunerdosse, DM1
Howard, DJ1
Eckel, RH1
Bragt, MC1
Kiortsis, DN3
Georgoula, M1
Elisaf, MS3
Gazi, IF2
Athyros, VG1
Tselepis, AD2
Kostapanos, M1
Papavasiliou, EC1

Trials

6 trials available for fenofibrate and Overweight

ArticleYear
Comparative Analysis of the Effects of Fish Oil and Fenofibrate on Plasma Metabolomic Profiles in Overweight and Obese Individuals.
    Molecular nutrition & food research, 2022, Volume: 66, Issue:2

    Topics: Double-Blind Method; Fatty Acids, Omega-3; Fenofibrate; Fish Oils; Humans; Obesity; Overweight; Trig

2022
Effect of rimonabant, micronised fenofibrate and their combination on cardiometabolic risk factors in overweight/obese patients: a pilot study.
    Expert opinion on pharmacotherapy, 2008, Volume: 9, Issue:16

    Topics: Blood Pressure; Body Mass Index; Body Weight; Cardiovascular System; Female; Fenofibrate; Heart; Hum

2008
Comparison of the effects of n-3 long chain polyunsaturated fatty acids and fenofibrate on markers of inflammation and vascular function, and on the serum lipoprotein profile in overweight and obese subjects.
    Nutrition, metabolism, and cardiovascular diseases : NMCD, 2012, Volume: 22, Issue:11

    Topics: Adult; Aged; Biomarkers; Cardiovascular Diseases; Chemokine CCL2; Cholesterol, HDL; Cholesterol, LDL

2012
Effect of orlistat, micronised fenofibrate and their combination on metabolic parameters in overweight and obese patients with the metabolic syndrome: the FenOrli study.
    Current medical research and opinion, 2005, Volume: 21, Issue:12

    Topics: Adult; Aged; Cholesterol, HDL; Cholesterol, LDL; Drug Therapy, Combination; Female; Fenofibrate; Hum

2005
The effect of orlistat and fenofibrate, alone or in combination, on small dense LDL and lipoprotein-associated phospholipase A2 in obese patients with metabolic syndrome.
    Atherosclerosis, 2007, Volume: 193, Issue:2

    Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Adult; Anti-Obesity Agents; Cardiovascular Diseases;

2007
The effects of orlistat and fenofibrate, alone or in combination, on high-density lipoprotein subfractions and pre-beta1-HDL levels in obese patients with metabolic syndrome.
    Diabetes, obesity & metabolism, 2008, Volume: 10, Issue:6

    Topics: Anti-Obesity Agents; Body Mass Index; Cholesterol, HDL; Drug Therapy, Combination; Female; Fenofibra

2008

Other Studies

2 other studies available for fenofibrate and Overweight

ArticleYear
Liver PPARα is crucial for whole-body fatty acid homeostasis and is protective against NAFLD.
    Gut, 2016, Volume: 65, Issue:7

    Topics: Adipocytes; Aging; Animals; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 4; Disease Models

2016
Fenofibrate administration does not affect muscle triglyceride concentration or insulin sensitivity in humans.
    Metabolism: clinical and experimental, 2011, Volume: 60, Issue:8

    Topics: Aged; Blood Glucose; Body Composition; Female; Fenofibrate; Glucose Tolerance Test; Humans; Hypolipi

2011