fenofibrate has been researched along with Osteoarthritis in 3 studies
Pharmavit: a polyvitamin product, comprising vitamins A, D2, B1, B2, B6, C, E, nicotinamide, & calcium pantothene; may be a promising agent for application to human populations exposed to carcinogenic and genetic hazards of ionizing radiation; RN from CHEMLINE
Osteoarthritis: A progressive, degenerative joint disease, the most common form of arthritis, especially in older persons. The disease is thought to result not from the aging process but from biochemical changes and biomechanical stresses affecting articular cartilage. In the foreign literature it is often called osteoarthrosis deformans.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Fenofibrate treatment was associated with significant decreases in pain score, tender joint count, duration of morning stiffness, disease activity score, Cochin index, and ESR." | 5.40 | Treatment of erosive osteoarthritis with peroxisome proliferator-activated receptor alpha agonist fenofibrate: a pilot study. ( Shirinsky, IV; Shirinsky, VS, 2014) |
| " Fenofibrate treated mice gained less body weight (BW) and had lower serum amyloid A (SAA) levels, but higher Interleukin (IL)-1α and MIP1α than other mice." | 3.80 | Statins and fibrates do not affect development of spontaneous cartilage damage in STR/Ort mice. ( Bastiaansen-Jenniskens, YM; Bierma-Zeinstra, SM; Botter, SM; Clockaerts, S; Gierman, LM; Kloppenburg, M; van Osch, GJ; Verhaar, JA; Wei, W; Weinans, H; Zuurmond, AM, 2014) |
| "Fenofibrate treatment was associated with significant decreases in pain score, tender joint count, duration of morning stiffness, disease activity score, Cochin index, and ESR." | 1.40 | Treatment of erosive osteoarthritis with peroxisome proliferator-activated receptor alpha agonist fenofibrate: a pilot study. ( Shirinsky, IV; Shirinsky, VS, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nogueira-Recalde, U | 1 |
| Lorenzo-Gómez, I | 1 |
| Blanco, FJ | 1 |
| Loza, MI | 1 |
| Grassi, D | 1 |
| Shirinsky, V | 1 |
| Shirinsky, I | 1 |
| Lotz, M | 1 |
| Robbins, PD | 1 |
| Domínguez, E | 1 |
| Caramés, B | 1 |
| Shirinsky, IV | 1 |
| Shirinsky, VS | 1 |
| Wei, W | 1 |
| Clockaerts, S | 1 |
| Bastiaansen-Jenniskens, YM | 1 |
| Gierman, LM | 1 |
| Botter, SM | 1 |
| Bierma-Zeinstra, SM | 1 |
| Weinans, H | 1 |
| Verhaar, JA | 1 |
| Kloppenburg, M | 1 |
| Zuurmond, AM | 1 |
| van Osch, GJ | 1 |
3 other studies available for fenofibrate and Osteoarthritis
| Article | Year |
|---|---|
Fibrates as drugs with senolytic and autophagic activity for osteoarthritis therapy.
Topics: Aging; Animals; Apoptosis; Autophagy; Cartilage Diseases; Cartilage, Articular; Cells, Cultured; Cel | 2019 |
Treatment of erosive osteoarthritis with peroxisome proliferator-activated receptor alpha agonist fenofibrate: a pilot study.
Topics: Analgesics, Non-Narcotic; Anti-Inflammatory Agents; Biomarkers; Female; Fenofibrate; Hand Joints; Hu | 2014 |
Statins and fibrates do not affect development of spontaneous cartilage damage in STR/Ort mice.
Topics: Animals; Arthritis, Experimental; Biomarkers; Body Weight; Cartilage, Articular; Diet; Drug Evaluati | 2014 |