fenofibrate has been researched along with Melanoma in 3 studies
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Melanoma: A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Mice melanoma cells (B16F10) were treated with fenofibrate or LPS or LPS + fenofibrate or pre-treated with CLI-095 (a TLR4 inhibitor), followed by fenofibrate." | 7.96 | The effect of fenofibrate, a PPARα activator on toll-like receptor-4 signal transduction in melanoma both in vitro and in vivo. ( Dana, N; Haghjooy Javanmard, S; Vaseghi, G, 2020) |
| "Mice melanoma cells (B16F10) were treated with fenofibrate or LPS or LPS + fenofibrate or pre-treated with CLI-095 (a TLR4 inhibitor), followed by fenofibrate." | 3.96 | The effect of fenofibrate, a PPARα activator on toll-like receptor-4 signal transduction in melanoma both in vitro and in vivo. ( Dana, N; Haghjooy Javanmard, S; Vaseghi, G, 2020) |
| " We previously reported the antimetastatic activity of the PPARalpha ligand, fenofibrate, against melanoma tumors in vivo." | 3.73 | Peroxisome proliferator-activated receptor alpha activation decreases metastatic potential of melanoma cells in vitro via down-regulation of Akt. ( Grabacka, M; Plonka, PM; Reiss, K; Urbanska, K, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (66.67) | 2.80 |
| Authors | Studies |
|---|---|
| Chang, L | 1 |
| Fu, S | 1 |
| Gao, T | 1 |
| Sang, X | 1 |
| Yang, H | 2 |
| Liu, X | 1 |
| Liu, Y | 1 |
| Zhang, N | 1 |
| Dana, N | 1 |
| Haghjooy Javanmard, S | 1 |
| Vaseghi, G | 1 |
| Grabacka, M | 1 |
| Plonka, PM | 1 |
| Urbanska, K | 1 |
| Reiss, K | 1 |
3 other studies available for fenofibrate and Melanoma
| Article | Year |
|---|---|
Regulating T-cell metabolic reprogramming and blocking PD-1 co-promote personalized postoperative autologous nanovaccines.
Topics: Animals; Antibodies; Fenofibrate; Immunotherapy; Melanoma; Mice; Programmed Cell Death 1 Receptor; T | 2023 |
The effect of fenofibrate, a PPARα activator on toll-like receptor-4 signal transduction in melanoma both in vitro and in vivo.
Topics: Animals; Cell Line, Tumor; Fenofibrate; Melanoma; Mice; Mice, Inbred C57BL; Myeloid Differentiation | 2020 |
Peroxisome proliferator-activated receptor alpha activation decreases metastatic potential of melanoma cells in vitro via down-regulation of Akt.
Topics: Animals; Cell Movement; Cell Proliferation; Down-Regulation; Enzyme Inhibitors; Fenofibrate; Humans; | 2006 |