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fenofibrate and Left Ventricular Hypertrophy

fenofibrate has been researched along with Left Ventricular Hypertrophy in 10 studies

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Research Excerpts

ExcerptRelevanceReference
"To investigate the effect of PPAR alpha activator fenofibrate on left ventricular hypertrophy and myocardium PPAR alpha (peroxisome proliferator-activated receptor-alpha) expression in spontaneously hypertensive rats (SHR)."7.74[PPAR alpha activator fenofibrate regressed left ventricular hypertrophy and increased myocardium PPAR alpha expression in spontaneously hypertensive rats]. ( Chen, HJ; Chen, JZ; Wang, XX; Yu, M, 2007)
"To investigate the effect of PPAR alpha activator fenofibrate on left ventricular hypertrophy and myocardium PPAR alpha (peroxisome proliferator-activated receptor-alpha) expression in spontaneously hypertensive rats (SHR)."3.74[PPAR alpha activator fenofibrate regressed left ventricular hypertrophy and increased myocardium PPAR alpha expression in spontaneously hypertensive rats]. ( Chen, HJ; Chen, JZ; Wang, XX; Yu, M, 2007)
"Treatment with fenofibrate, a PPARĪ± agonist, normalized both FA and glucose uptake while reducing LV dilation caused by AR."1.42Transcriptional Changes Associated with Long-Term Left Ventricle Volume Overload in Rats: Impact on Enzymes Related to Myocardial Energy Metabolism. ( Arsenault, M; Couet, J; Dhahri, W; Drolet, MC; Gascon, S; Lachance, D; Lecomte, R; Rousseau, JA; Roussel, E; Sarrhini, O; Walsh-Wilkinson, E, 2015)
"Fenofibrate was used as the PPARĪ± agonist."1.37Reactivation of peroxisome proliferator-activated receptor alpha in spontaneously hypertensive rat: age-associated paradoxical effect on the heart. ( Nair, RR; Purushothaman, S; Sathik, MM, 2011)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (50.00)29.6817
2010's5 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dhyani, N1
Saidullah, B1
Fahim, M1
Omanwar, S1
Roussel, E1
Drolet, MC1
Walsh-Wilkinson, E1
Dhahri, W1
Lachance, D1
Gascon, S1
Sarrhini, O1
Rousseau, JA1
Lecomte, R1
Couet, J1
Arsenault, M1
Zhang, J1
Cheng, Y1
Gu, J1
Wang, S1
Zhou, S1
Wang, Y1
Tan, Y1
Feng, W1
Fu, Y1
Mellen, N1
Cheng, R1
Ma, J1
Zhang, C1
Li, Z1
Cai, L1
Baraka, A1
AbdelGawad, H1
Purushothaman, S1
Sathik, MM1
Nair, RR1
Irukayama-Tomobe, Y1
Miyauchi, T1
Sakai, S1
Kasuya, Y1
Ogata, T1
Takanashi, M1
Iemitsu, M1
Sudo, T1
Goto, K1
Yamaguchi, I1
Erol, A1
Ichihara, S1
Obata, K1
Yamada, Y1
Nagata, K1
Noda, A1
Ichihara, G1
Yamada, A1
Kato, T1
Izawa, H1
Murohara, T1
Yokota, M1
Lebrasseur, NK1
Duhaney, TA1
De Silva, DS1
Cui, L1
Ip, PC1
Joseph, L1
Sam, F1
Chen, HJ1
Chen, JZ1
Wang, XX1
Yu, M1

Other Studies

10 other studies available for fenofibrate and Left Ventricular Hypertrophy

ArticleYear
Fenofibrate ameliorates neural, mechanical, chemical, and electrical alterations in the murine model of heart failure.
    Human & experimental toxicology, 2019, Volume: 38, Issue:10

    Topics: Animals; Baroreflex; Blood Pressure; Disease Models, Animal; Electrocardiography; Energy Metabolism;

2019
Transcriptional Changes Associated with Long-Term Left Ventricle Volume Overload in Rats: Impact on Enzymes Related to Myocardial Energy Metabolism.
    BioMed research international, 2015, Volume: 2015

    Topics: Animals; Aortic Valve Insufficiency; Cardiac Volume; Disease Models, Animal; Energy Metabolism; Feno

2015
Fenofibrate increases cardiac autophagy via FGF21/SIRT1 and prevents fibrosis and inflammation in the hearts of Type 1 diabetic mice.
    Clinical science (London, England : 1979), 2016, Volume: 130, Issue:8

    Topics: Animals; Autophagy; Blood Glucose; Cell Line; Diabetes Mellitus, Experimental; Diabetes Mellitus, Ty

2016
Targeting apoptosis in the heart of streptozotocin-induced diabetic rats.
    Journal of cardiovascular pharmacology and therapeutics, 2010, Volume: 15, Issue:2

    Topics: Animals; Apoptosis; Cardiomyopathies; Diabetes Complications; Diabetes Mellitus, Experimental; Fenof

2010
Reactivation of peroxisome proliferator-activated receptor alpha in spontaneously hypertensive rat: age-associated paradoxical effect on the heart.
    Journal of cardiovascular pharmacology, 2011, Volume: 58, Issue:3

    Topics: Aging; Animals; Azo Compounds; Blood Pressure; Body Weight; Cholesterol; Disease Models, Animal; Ene

2011
Endothelin-1-induced cardiac hypertrophy is inhibited by activation of peroxisome proliferator-activated receptor-alpha partly via blockade of c-Jun NH2-terminal kinase pathway.
    Circulation, 2004, Feb-24, Volume: 109, Issue:7

    Topics: Animals; Animals, Newborn; Aorta; Cells, Cultured; Disease Models, Animal; Endothelin-1; Fenofibrate

2004
PPARalpha activators may play role for the regression of ventricular hypertrophy in hypertensive and hyperlipidemic patients.
    Medical hypotheses, 2006, Volume: 66, Issue:5

    Topics: Clinical Trials as Topic; Evidence-Based Medicine; Fenofibrate; Humans; Hyperlipidemias; Hypertensio

2006
Attenuation of cardiac dysfunction by a PPAR-alpha agonist is associated with down-regulation of redox-regulated transcription factors.
    Journal of molecular and cellular cardiology, 2006, Volume: 41, Issue:2

    Topics: Animals; Cytokines; Down-Regulation; Fenofibrate; Glucose; Heart Ventricles; Hypertension; Hypertrop

2006
Effects of fenofibrate on cardiac remodeling in aldosterone-induced hypertension.
    Hypertension (Dallas, Tex. : 1979), 2007, Volume: 50, Issue:3

    Topics: Aldosterone; Animals; Blood Pressure; Extracellular Matrix; Fenofibrate; Fibrosis; Heart; Heart Rate

2007
[PPAR alpha activator fenofibrate regressed left ventricular hypertrophy and increased myocardium PPAR alpha expression in spontaneously hypertensive rats].
    Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences, 2007, Volume: 36, Issue:5

    Topics: Animals; Blood Pressure; Blotting, Western; Fenofibrate; Hypertension; Hypertrophy, Left Ventricular

2007